Research Topics
| Lawrence R StanberrySummaryAffiliation: University of Texas Medical Branch Country: USA Publications
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Detail Information
Publications
Genital herpes simplex virus infection in the adolescent: special considerations for managementLawrence R Stanberry
Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas 77555 0351, USA
Paediatr Drugs 4:291-7. 2002..All adolescents should have follow-up visits to complete education and counseling and to assess compliance with antiviral therapy...- Progress in vaccines for sexually transmitted diseasesLawrence R Stanberry
Department of Pediatrics and the Sealy Center for Vaccine Development, University of Texas Medical Branch, Children s Hospital, 301 University Boulevard, Galveston, TX 77555, USA
Infect Dis Clin North Am 19:477-90, xi. 2005..Behavioral research suggests that these vaccines will likely find acceptance among health care providers and consumers... - Longitudinal risk of herpes simplex virus (HSV) type 1, HSV type 2, and cytomegalovirus infections among young adolescent girlsLawrence R Stanberry
Department of Pediatrics, Children s Hospital Medical Center, Cincinnati, Ohio, USA
Clin Infect Dis 39:1433-8. 2004..Cross-sectional seroprevalence studies indicate that infections with herpes simplex virus (HSV) types 1 (HSV-1) and 2 (HSV-2) and cytomegalovirus (CMV) are common. However, data on the rates of acquisition of these infections are limited... - Glycoprotein-D-adjuvant vaccine to prevent genital herpesLawrence R Stanberry
Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston 77555 0351, USA
N Engl J Med 347:1652-61. 2002..An effective prophylactic vaccine would help control the spread of genital herpes... - Neonatal herpes in premature infants: a special problemLawrence R Stanberry
Department of Pediatrics and the Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, 301 University Blvd, Galveston, TX 77555-0351, USA
Pediatrics 118:2543-4. 2006 - Impact of immunization with glycoprotein D2/AS04 on herpes simplex virus type 2 shedding into the genital tract in guinea pigs that become infectedNigel Bourne
Department of Pediatrics, University of Texas Medical Branch, Galveston, 77555, USA
J Infect Dis 192:2117-23. 2005..However, the amount of virus shed was significantly reduced, as measured by qPCR. These data suggest that immunization could affect transmission by altering viral shedding patterns... 
Human monoclonal antibody AVP-21D9 to protective antigen reduces dissemination of the Bacillus anthracis Ames strain from the lungs in a rabbit modelJohnny W Peterson
Department of Microbiology and Immunology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1070, USA
Infect Immun 75:3414-24. 2007..Early treatment increased the efficacy progressively and in a dose-dependent manner. Thus, AVP-21D9 could offer an adjunct or alternative clinical treatment regimen against inhalation anthrax...- Herpes simplex virus (HSV) type 2 glycoprotein D subunit vaccines and protection against genital HSV-1 or HSV-2 disease in guinea pigsNigel Bourne
Division of Infectious Diseases, Children s Hospital Medical Center, Cincinnati, Ohio, USA
J Infect Dis 187:542-9. 2003.... - Benzalkonium chloride causes colposcopic changes and increased susceptibility to genital herpes infection in miceKathleen L Vincent
Department of Obstetrics and Gynecology, Center for Biomedical Engineering, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA
Sex Transm Dis 37:579-84. 2010..Endoscopic colposcopy could be employed in small animals allowing colposcopy to be used as one component in a multifactorial safety testing paradigm... - Parental acceptance of adolescent vaccines within school-based health centresMary B Short
Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, 77555, USA
Herpes 12:23-7. 2005..Efforts to enhance vaccine uptake for adolescents should focus on promoting positive perceptions of the location of vaccination and universal recommendations... - High resolution imaging of epithelial injury in the sheep cervicovaginal tract: a promising model for testing safety of candidate microbicidesKathleen L Vincent
Department of Obstetrics and Gynecology, Division of Gynecology, University of Texas Medical Branch, Galveston, TX 77555, USA
Sex Transm Dis 36:312-8. 2009..In addition, optical coherence tomography (OCT) could enable high resolution visualization of tissue morphology and noninvasive assessment of microbicide-induced epithelial injury... - Adolescent issues associated with knowledge of and access to topical microbicidesMary B Short
Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas 77555-0319, USA
J Womens Health (Larchmt) 13:1127-36. 2004..CONCLUSIONS: Consideration of the adolescent-specific issues in the design of microbicides and marketing strategies may be crucial for adolescent adoption of this female-controlled method... - Effects of candidate vaginally-applied microbicide compounds on innate immune cellsGregg N Milligan
Sealy Center for Vaccine Development, 301 University Boulevard, Galveston, TX 77555 0436, USA
J Reprod Immunol 66:103-16. 2005.... - Factors predicting the acceptance of herpes simplex virus type 2 antibody testing among adolescents and young adultsGregory D Zimet
Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA
Sex Transm Dis 31:665-9. 2004..The rates and determinants of acceptance of herpes simplex virus type 2 (HSV-2) testing have not been adequately studied... - Prevalence of herpes simplex virus types 1 and 2 among children and adolescents attending a sexual abuse clinicStephanie Ramos
Department of Pediatrics, University of Texas Medical Branch at Galveston, Galveston, TX 77555-0319, USA
Pediatr Infect Dis J 25:902-5. 2006..The Focus test has an unacceptably high rate of false-positive results in children; however, Biokit may be an acceptable substitute for WB in evaluating children for HSV-2 antibodies... - Application of optical coherence tomography for monitoring changes in cervicovaginal epithelial morphology in macaques: potential for assessment of microbicide safetyKathleen L Vincent
University of Texas Medical Branch, Galveston, Texas 77555 0319, USA
Sex Transm Dis 35:269-75. 2008..Optical coherence tomography (OCT), a high-resolution, in-depth cross-sectional imaging modality, was utilized in conjunction with colposcopy to assess induced cervicovaginal epithelial changes that may predict product safety... - Safety and immunogenicity of glycoprotein D-adjuvant genital herpes vaccineDavid I Bernstein
Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA
Clin Infect Dis 40:1271-81. 2005.... - Topical microbicide use by adolescent girls: concerns about timing, efficacy, and safetyMary B Short
Department of Pediatrics, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-0319, USA
Sex Transm Dis 30:854-8. 2003..CONCLUSION: This study demonstrated the importance of understanding the unique needs and perspectives of adolescent girls and the adults who have an influence on their use... - Modification of primary and recurrent genital herpes in guinea pigs by passive immunizationNigel Bourne
Children s Hospital Medical Center, Division of Infectious Diseases, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
J Gen Virol 83:2797-801. 2002..The amount of DNA in the ganglia of As+72-treated animals was not significantly lower than that of controls. These observations have implications for both the dynamics of latency establishment and desirable vaccine characteristics... - Non-exclusivity in adolescent girls' romantic relationshipsMary B Short
Department of Pediatrics, University of Texas Medical Branch, University of Texas Medical Branch at Galveston, Galveston, Texas 77555 0319, USA
Sex Transm Dis 30:752-5. 2003..As adolescents develop intimate relationships skills, they might change romantic partners often. Little is known about this developmental phenomenon... - Use of immunostimulatory sequence-containing oligonucleotides as topical therapy for genital herpes simplex virus type 2 infectionRichard B Pyles
Department of Pediatrics and the Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas 77555, USA
J Virol 76:11387-96. 2002..These data suggest that ISS may be useful in the treatment and control of genital herpes in humans... - VivaGel (SPL7013 Gel): a candidate dendrimer--microbicide for the prevention of HIV and HSV infectionRichard Rupp
Sealy Center for Vaccine Development and Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas 77555 1119, USA
Int J Nanomedicine 2:561-6. 2007..VivaGel appears to be well tolerated in both animals and humans. This review summarizes the studies of VivaGel and its active ingredient, SPL7013... - The relationship between STD locus of control and STD acquisition among adolescent girlsSusan L Rosenthal
Department of Pediatrics, University of Texas Medical Branch-Children's Hospital, Galveston 77555, USA
Adolescence 37:83-92. 2002..However, understanding an individual's locus of control may be helpful in providing appropriate counseling. Future research could examine how adolescent girls form their perceptions of control over STD acquisition... - Optical coherence tomography compared with colposcopy for assessment of vaginal epithelial damage: a randomized controlled trialKathleen L Vincent
University of Texas Medical Branch, Galveston, Texas 77555 1156, USA
Obstet Gynecol 118:1354-61. 2011..This randomized, double-blinded, clinical study compared optical coherence tomography to colposcopy for the evaluation of epithelial injury in women using placebo or nonoxynol-9... - Efficacy and toxicity of zinc salts as candidate topical microbicides against vaginal herpes simplex virus type 2 infectionNigel Bourne
Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd, Galveston, Texas, 77555 0436, USA
Antimicrob Agents Chemother 49:1181-3. 2005.... 
Seroprevalence of cytomegalovirus (CMV) and risk factors for infection in adolescent malesLaura Patricia Stadler
Department of Pediatrics, Division of Infectious Diseases, University of Kentucky, Lexington, KY 40536 0284, USA
Clin Infect Dis 51:e76-81. 2010..Although the seroprevalence of CMV and associated exposure and behavioral risk factors have been reported in adolescent females, few data exist about males...- Pediatrics and herpes simplex virus vaccinesRichard Rupp
Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX 77555 1119, USA
Semin Pediatr Infect Dis 16:31-7. 2005..Further research is required to improve on and fully understand the implications of prophylactic herpes simplex vaccines... - Vaccines for sexually transmitted infectionsRichard E Rupp
Division of Adolescent and Behavioral Health, Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX, USA
Pediatr Ann 34:818-20, 822-4. 2005..As these vaccines become licensed, their successful implementation will require the support of professional organizations, families, and providers... - Clinical trials of prophylactic and therapeutic herpes simplex virus vaccinesLawrence R Stanberry
The Sealy Center for Vaccine Development, The University of Texas Medical Branch, Galveston, Texas 77555 0351, USA
Herpes 11:161A-169A. 2004..Further research is needed to define determinants of immunity to HSV-2, including identifying HSV-2 antigens, in order to design more effective vaccines... - Entry of inflammatory cells into the mouse vagina following application of candidate microbicides: comparison of detergent-based and sulfated polymer-based agentsGregg N Milligan
Department of Pediatrics and the Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas 77555 0436, USA
Sex Transm Dis 29:597-605. 2002..A murine model was developed to test for induction of inflammatory responses following application of candidate microbicides... - Parental reasons for utilization of an urban pediatric emergency department during the 2009 H1N1 influenza epidemicMelissa S Stockwell
Division of General Pediatrics, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, 622 W 168th St, VC 402, New York, NY 10032, USA
Pediatr Emerg Care 27:261-5. 2011..Children with a usual source of care presenting for influenza-like illness (ILI) symptoms were compared with those presenting with other symptoms... - New biomedical approaches for sexually transmitted infection prevention: vaccines and microbicidesRichard Rupp
Department of Pediatrics, University of Texas Medical Branch, Children s Hospital, 301 University Boulevard, Galveston, TX 77555 1119, USA
Adolesc Med Clin 15:393-407. 2004..It seems that young women and teenagers would be interested in using microbicides. Correct and consistent use of microbicides will require taking women's preferences into account during product development and marketing... - Reducing the stigma of herpes simplex virus infection: lessons from an online video contestLee S Shearer
Department of Pediatrics, Children s Hospital of New York at New York Presbyterian Hospital, New York, NY, USA
Sex Health 9:438-44. 2012..The aims of this study were to describe the range of destigmatising strategies used by the public in brief online videos, and to describe videos that were successful or unsuccessful in creating a destigmatising message... - Human monoclonal anti-protective antigen antibody completely protects rabbits and is synergistic with ciprofloxacin in protecting mice and guinea pigs against inhalation anthraxJohnny W Peterson
Sealy Center for Vaccine Development, Center for Biodefense and Emerging Infections, Department of Microbiology and Immunology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 1070, USA
Infect Immun 74:1016-24. 2006..Taken together, the effectiveness of human anti-PA antibody alone or in combination with low ciprofloxacin levels may provide the basis for an improved strategy for prophylaxis or treatment following inhalation anthrax infection... - Screening for neonatal herpes: physicians' descriptions of discussions with parentsSian Cotton
Division of Adolescent Medicine, Children s Hospital Medical Center, Cincinnati, OH, USA
Herpes 9:60-3. 2002..Future research can determine which strategies are most effective, which are associated with negative psychological outcomes, and how medical students and residents can be better trained to screen for this diagnosis... - Effect of candidate vaginally-applied microbicide compounds on recognition of antigen by CD4+ and CD8+ T lymphocytesGregg N Milligan
Sealy Center for Vaccine Development, 301 University Blvd, Galveston, Texas 77555 0436, USA
Biol Reprod 71:1638-45. 2004..The assays described in this study represent a useful means to screen candidate topical microbicide compounds for inappropriate interactions with immune cells and may be useful for prioritization of candidate microbicide compounds... - Randomized controlled trial of an adjuvanted human papillomavirus (HPV) type 6 L2E7 vaccine: infection of external anogenital warts with multiple HPV types and failure of therapeutic vaccinationPierre Vandepapeliere
GlaxoSmithKline Biologicals, Rixensart, Belgium
J Infect Dis 192:2099-107. 2005..A therapeutic vaccine composed of HPV-6 L2E7 fusion protein and AS02A adjuvant was evaluated in conjunction with conventional therapies in subjects with anogenital warts... - Predictors of herpes simplex virus type 2 antibody positivity among persons with no history of genital herpesKenneth H Fife
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
Sex Transm Dis 31:676-81. 2004..The demographic, historical, and behavioral factors that predict a positive herpes simplex virus type 2 (HSV-2) antibody test in persons without a history of genital herpes have not been well-defined... - Parental acceptability of vaccines for sexually transmitted infectionsSusan L Rosenthal
Arch Pediatr Adolesc Med 159:190-2. 2005 - Is herpes simplex virus type 1 (HSV-1) now more common than HSV-2 in first episodes of genital herpes?Gregory J Mertz
Sex Transm Dis 30:801-2. 2003 - Neonatal herpes should be a reportable diseaseH Hunter Handsfield
University of Washington, Center for AIDS and STD, Harborview Medical Center, Seattle, Washington 98104, USA
Sex Transm Dis 32:521-5. 2005..Neonatal herpes should be a reportable condition... - Estimating the population prevalence of HPVSusan C Weller
JAMA 297:876-8. 2007