Research Topics
Species | Boryana StamovaSummaryAffiliation: University of California Country: USA Publications
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Publications
Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral bloodBoryana S Stamova
Department of Neurology and M, Institute, University of California at Davis Medical Center, Sacramento, CA 95817, USA
BMC Med Genomics 2:49. 2009..These genes should be useful as normalization genes for microarray and RT-PCR whole blood studies of human physiology, metabolism and disease...
The X-chromosome has a different pattern of gene expression in women compared with men with ischemic strokeBoryana Stamova
Departments of Neurology, University of California at Davis, MIND Institute and Department of Neurology, 2805 50th Street, Sacramento CA 95817, USA
Stroke 43:326-34. 2012..However, sex differences in immune response to ischemia may exist. We hypothesized that differential expression of X-chromosome genes in blood immune cells contribute to differences between men and women with ischemic stroke...- Correlations between gene expression and mercury levels in blood of boys with and without autismBoryana Stamova
Department of Neurology, University of California at Davis Medical Center, Sacramento, CA 95817, USA
Neurotox Res 19:31-48. 2011..These findings might suggest different genetic transcriptional programs associated with mercury in AU compared to TD children... - Gene expression profiling of blood for the prediction of ischemic strokeBoryana Stamova
Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, Calif 95817, USA
Stroke 41:2171-7. 2010..This study aimed to (1) replicate in a larger cohort our previous study using gene expression profiling to predict ischemic stroke; and (2) refine prediction of ischemic stroke by including control groups relevant to ischemic stroke... - Effects of gender on gene expression in the blood of ischemic stroke patientsYingfang Tian
Department of Neurology, The MIND Institute, University of California at Davis, Sacramento, CA, USA
J Cereb Blood Flow Metab 32:780-91. 2012..Gender affects gene expression in the blood of IS patients, which likely implies gender differences in immune, inflammatory, and cell death responses to stroke... - Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controlsYingfang Tian
Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, California 95817, USA
Gend Med 9:68-75.e3. 2012.... - Signatures of cardioembolic and large-vessel ischemic strokeGlen C Jickling
Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
Ann Neurol 68:681-92. 2010..We sought to determine whether gene expression signatures in blood can distinguish between cardioembolic and large-vessel causes of stroke, and whether these profiles can predict stroke etiology in the cryptogenic group... - Profiles of lacunar and nonlacunar strokeGlen C Jickling
Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
Ann Neurol 70:477-85. 2011..We sought to distinguish lacunar from nonlacunar causes of SDIs using a gene expression profile... - Correlations of gene expression with blood lead levels in children with autism compared to typically developing controlsYingfang Tian
Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
Neurotox Res 19:1-13. 2011..We postulate that this may relate to the underlying genetic differences between the two groups, though other explanations cannot be excluded... - Ischemic transient neurological events identified by immune response to cerebral ischemiaGlen C Jickling
University of California at Davis, MIND Institute, 2805 50th Street, Sacramento, CA 95817, USA
Stroke 43:1006-12. 2012..Ischemia of cerebral tissue elicits an immune response in stroke and transient ischemic attack (TIA). This response, as detected by RNA expressed in immune cells, could potentially distinguish ischemic from nonischemic TNE... - Prediction of cardioembolic, arterial, and lacunar causes of cryptogenic stroke by gene expression and infarct locationGlen C Jickling
Department of Neurology and MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
Stroke 43:2036-41. 2012..We demonstrate how gene expression profiles in blood can be used in conjunction with a measure of infarct location on neuroimaging to predict a probable cause in cryptogenic stroke... - RNA expression profiles from blood for the diagnosis of stroke and its causesFrank R Sharp
Department of Neurology, University of California at Davis, Sacramento, CA, USA
J Child Neurol 26:1131-6. 2011..These profiles will be useful for predicting the causes of cryptogenic stroke. The results in adults suggest that similar diagnostic tools could be developed for children... - Brief focal cerebral ischemia that simulates transient ischemic attacks in humans regulates gene expression in rat peripheral bloodXinhua Zhan
Department of Neurology and M I N D Institute, University of California at Davis, Sacramento, California 95817, USA
J Cereb Blood Flow Metab 30:110-8. 2010..We postulate that this will also occur in humans... - Molecular markers and mechanisms of stroke: RNA studies of blood in animals and humansFrank R Sharp
Department of Neurology, MIND Institute, University of California at Davis, Sacramento, California 95817, USA
J Cereb Blood Flow Metab 31:1513-31. 2011..New techniques to measure all coding and noncoding RNAs along with alternatively spliced transcripts will markedly advance molecular studies of human stroke... - Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brainHuichun Xu
Department of Neurology and M I N D Institute, University of California at Davis, Sacramento, CA 95817, USA
Stroke 41:2744-9. 2010..Thus, RNA expression was assessed in the blood of individuals with and without extensive WMH to search for evidence of oxidative stress, inflammation, and other abnormalities described in WMH lesions in brain... - Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cellsDa Zhi Liu
Department of Neurology and the M I N D Institute, University of California at Davis, Sacramento, CA 95817, USA
Gene 495:120-7. 2012..g., miR-370, miR-9, miR-672) in NBCs are associated with cancer pathways. These results provide a library of negative mRNAmiRNA networks that are likely involved in the cellular processes of differentiation and division... - Genome response to tissue plasminogen activator in experimental ischemic strokeGlen C Jickling
Department of Neurology and M, I, N, d, Institute, University of California at Davis, Sacramento, California 95817, USA
BMC Genomics 11:254. 2010..To further delineate tPA functions in the blood, we examined the gene expression profiles induced by tPA in a rat model of ischemic stroke... - Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot studyYingfang Tian
MIND Institute and Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
BMC Med Genomics 5:49. 2012..This study determined if gene expression in blood correlated significantly with IA and/or HI rating scale scores in participants with TS... - Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizuresDa Zhi Liu
Department of Neurology and the M I N D Institute, University of California at Davis Medical Center, Sacramento, California 95817, USA
J Cereb Blood Flow Metab 30:92-101. 2010.... - Catecholamine-related gene expression in blood correlates with tic severity in tourette syndromeJoan Gunther
Department of Neurology and MIND Institute, University of California at Davis, 2805 50th Street, Sacramento, CA 95817, USA
Psychiatry Res 200:593-601. 2012..Findings built on previous work suggest that at least some genes expressed peripherally are relevant for central nervous system (CNS) pathology in the brain of individuals with TS...