Hinrich Staecker

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi Oxidative stress in aging in the C57B16/J mouse cochlea
    H Staecker
    Division of Otolaryngology, University of Maryland Medical School, Baltimore, Maryland 21201 1619, USA
    Acta Otolaryngol 121:666-72. 2001
  2. ncbi Broadening the spectrum of treatment options for SNHL
    Hinrich Staecker
    Department of Otolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore 21201, USA
    Arch Otolaryngol Head Neck Surg 131:734. 2005
  3. ncbi Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer
    Hinrich Staecker
    Otolaryngology Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, Kansas 66160, USA
    Otol Neurotol 28:223-31. 2007
  4. ncbi Drug delivery to the inner ear using gene therapy
    Hinrich Staecker
    Division of Otolaryngology, University of Maryland School of Medicine, 16 S Eutaw Street, Suite 500, Baltimore, MD 21201, USA
    Otolaryngol Clin North Am 37:1091-108. 2004
  5. ncbi Topical steroid therapy using the Silverstein Microwick in sudden sensorineural hearing loss after failure of conventional treatment
    France Van Wijck
    Department of Otorhinolaryngology, University of Liege, Liege, Belgium
    Acta Otolaryngol 127:1012-7. 2007
  6. ncbi Vertigo and abacavir
    Lori E Fantry
    University of Maryland Medical School Institute of Human Virology, Baltimore, Maryland, USA
    AIDS Patient Care STDS 16:5-7. 2002
  7. ncbi Steroid perfusion of the inner ear for sudden sensorineural hearing loss after failure of conventional therapy: a pilot study
    Philippe P Lefebvre
    Department of Otorhinolaryngology, University of Liege, Liege, Belgium
    Acta Otolaryngol 122:698-702. 2002
  8. ncbi Transsynaptic delivery of nanoparticles to the central auditory nervous system
    Mark Praetorius
    Department of Otolaryngology, Head and Neck Surgery, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Acta Otolaryngol 127:486-90. 2007
  9. ncbi Vector-mediated delivery of bcl-2 prevents degeneration of auditory hair cells and neurons after injury
    Hinrich Staecker
    Department of Otolaryngology, University of Kansas, Kansas City, Kans 66160, USA
    ORL J Otorhinolaryngol Relat Spec 69:43-50. 2007
  10. ncbi Pharmacodynamics of adenovector distribution within the inner ear tissues of the mouse
    Mark Praetorius
    Department of Otolaryngology, University of Heidelberg Medical Center, Heidelberg, Germany
    Hear Res 227:53-8. 2007

Collaborators

Detail Information

Publications15

  1. ncbi Oxidative stress in aging in the C57B16/J mouse cochlea
    H Staecker
    Division of Otolaryngology, University of Maryland Medical School, Baltimore, Maryland 21201 1619, USA
    Acta Otolaryngol 121:666-72. 2001
    ....
  2. ncbi Broadening the spectrum of treatment options for SNHL
    Hinrich Staecker
    Department of Otolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore 21201, USA
    Arch Otolaryngol Head Neck Surg 131:734. 2005
  3. ncbi Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer
    Hinrich Staecker
    Otolaryngology Head and Neck Surgery, University of Kansas School of Medicine, Kansas City, Kansas 66160, USA
    Otol Neurotol 28:223-31. 2007
    ..Delivery of math1 using an adenovector (Admath1.11D) results in vestibular hair cell regeneration and recovery of balance function in ototoxin-treated adult mice...
  4. ncbi Drug delivery to the inner ear using gene therapy
    Hinrich Staecker
    Division of Otolaryngology, University of Maryland School of Medicine, 16 S Eutaw Street, Suite 500, Baltimore, MD 21201, USA
    Otolaryngol Clin North Am 37:1091-108. 2004
    ..As the understanding of gene therapy improves, investigators will be able to move toward targeted single-gene replacement to treat disorders such as connexin mutations and applying gene therapy to sensory cell replacement...
  5. ncbi Topical steroid therapy using the Silverstein Microwick in sudden sensorineural hearing loss after failure of conventional treatment
    France Van Wijck
    Department of Otorhinolaryngology, University of Liege, Liege, Belgium
    Acta Otolaryngol 127:1012-7. 2007
    ..Local administration of steroids to the inner ear through the round window route improves hearing in patients after failure of conventional therapy...
  6. ncbi Vertigo and abacavir
    Lori E Fantry
    University of Maryland Medical School Institute of Human Virology, Baltimore, Maryland, USA
    AIDS Patient Care STDS 16:5-7. 2002
    ..The mechanism by which abacavir appeared to be associated with vertigo in this patient is unknown...
  7. ncbi Steroid perfusion of the inner ear for sudden sensorineural hearing loss after failure of conventional therapy: a pilot study
    Philippe P Lefebvre
    Department of Otorhinolaryngology, University of Liege, Liege, Belgium
    Acta Otolaryngol 122:698-702. 2002
    ..In conclusion, methylprednisolone perfused at the level of the round window membrane resulted in significant recovery of hearing function after the failure of standard treatment of SSHL...
  8. ncbi Transsynaptic delivery of nanoparticles to the central auditory nervous system
    Mark Praetorius
    Department of Otolaryngology, Head and Neck Surgery, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Acta Otolaryngol 127:486-90. 2007
    ..Silica nanoparticles may serve as a nonviral delivery system to the sensory hair cells, spiral ganglion cells within the cochlea, and the vestibular organ, as well as the cochlear nucleus...
  9. ncbi Vector-mediated delivery of bcl-2 prevents degeneration of auditory hair cells and neurons after injury
    Hinrich Staecker
    Department of Otolaryngology, University of Kansas, Kansas City, Kans 66160, USA
    ORL J Otorhinolaryngol Relat Spec 69:43-50. 2007
    ..To test the hypothesis that bcl-2 prevents oxidative stress-induced apoptosis of auditory sensory cells in explants of the organ of Corti and dissociated cell cultures of the spiral ganglion...
  10. ncbi Pharmacodynamics of adenovector distribution within the inner ear tissues of the mouse
    Mark Praetorius
    Department of Otolaryngology, University of Heidelberg Medical Center, Heidelberg, Germany
    Hear Res 227:53-8. 2007
    ..Understanding these basic distribution patterns and parameters for delivery are important for the design of gene delivery vectors and vital for modeling dose responses to achieve safe efficacious delivery of a therapeutic agent...
  11. ncbi Advances in inner ear gene therapy: exploring cochlear protection and regeneration
    Carrie R Maiorana
    Department of Otolaryngology, University of Kansas, Kansas City, KS 66160, USA
    Curr Opin Otolaryngol Head Neck Surg 13:308-12. 2005
    ..Gene therapy can protect the inner ear from damage and even restore function through the regeneration of hair cells...
  12. ncbi Microperfusion of the inner ear
    Philippe P Lefebvre
    Dept. of Otorhinolaryngology, , Belgium
    Acta Otorhinolaryngol Belg 56:365-8. 2002
  13. ncbi Hearing preservation after inner ear gene therapy: the effect of vector and surgical approach
    Mark Praetorius
    Department of Otolaryngology, University Hospital of the Saarland, Homburg/Saar, Germany
    ORL J Otorhinolaryngol Relat Spec 65:211-4. 2003
    ..Injection of comparable doses of vector into a basal turn cochleostomy resulted in high-frequency hearing loss. Addition of a pancaspase inhibitor protected hearing when larger volumes of fluid were administered to the inner ear...
  14. ncbi Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation
    Ulysses Scarpidis
    Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, New York, USA
    Otol Neurotol 24:409-17. 2003
    ..CONCLUSION: Blocking the JNK/c-Jun cell death pathway is a feasible approach to treating oxidative stress-induced apoptosis within the cochlea and may have application as an otoprotective strategy during cochlear implantation...
  15. ncbi The effect of diabetes on sensorineural hearing loss
    Venkata Kakarlapudi
    Department of Otolaryngology, Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Otol Neurotol 24:382-6. 2003
    ..This may have been due to microangiopathic disease in the inner ear...