Research Topics
| Anon SrikiatkhachornSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
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Detail Information
Publications
Dengue viral RNA levels in peripheral blood mononuclear cells are associated with disease severity and preexisting dengue immune statusAnon Srikiatkhachorn
Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
PLoS ONE 7:e51335. 2012..The in vivo targets of DENV and the relation between the viral burden in these cells and disease severity are not known...- Dengue--how best to classify itAnon Srikiatkhachorn
Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Clin Infect Dis 53:563-7. 2011..The 2009 classification differs significantly from the previous classification in both conceptual and practical levels. The impacts of the new classification on clinical practice, dengue research, and public health policy are discussed... - Virus-induced decline in soluble vascular endothelial growth receptor 2 is associated with plasma leakage in dengue hemorrhagic FeverAnon Srikiatkhachorn
Center for Infectious Diseases and Vaccine Research, Rm S5 326, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655 0002, USA
J Virol 81:1592-600. 2007..Dengue virus-induced changes in surface and soluble VEGFR2 expression may be an important mechanism of plasma leakage in DHF... - Dengue hemorrhagic fever: the sensitivity and specificity of the world health organization definition for identification of severe cases of dengue in Thailand, 1994-2005Anon Srikiatkhachorn
University of Massachusetts Medical School, Worcester, MA 01655, USA
Clin Infect Dis 50:1135-43. 2010..The ability of these guidelines to categorize severe dengue illness has recently been questioned... 
Plasma leakage in dengue haemorrhagic feverAnon Srikiatkhachorn
University of Massachusetts Medical School, Center for Infectious Diseases and Vaccine Research, Worcester, MA 01655 0002, USA
Thromb Haemost 102:1042-9. 2009..Insights into the mechanisms that confer protection or cause disease are critical in the development of prophylactic and therapeutic modalities for this important disease...- Markers of dengue disease severityAnon Srikiatkhachorn
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue, North, Worcester 01655, USA
Curr Top Microbiol Immunol 338:67-82. 2010..Ideally, clinical and laboratory predictive tools should be suitable for resource poor countries where dengue is endemic... 
Natural history of plasma leakage in dengue hemorrhagic fever: a serial ultrasonographic studyAnon Srikiatkhachorn
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Pediatr Infect Dis J 26:283-90; discussion 291-2. 2007..We employed serial ultrasound examination to delineate the locations and the timing of plasma leakage and to evaluate the usefulness of ultrasound in detecting plasma leakage in DHF...- Prediction of dengue disease severity among pediatric Thai patients using early clinical laboratory indicatorsJames A Potts
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA
PLoS Negl Trop Dis 4:e769. 2010..Earlier diagnosis of severe dengue illnesses would have a substantial impact on the allocation of health resources in endemic countries... - Classification of dengue illness based on readily available laboratory dataJames A Potts
Center for Infectious Disease and Vaccine Research and Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
Am J Trop Med Hyg 83:781-8. 2010..These models could be used to calculate a probability and classify patients based on readily available clinical laboratory data, and they will need to be validated in other dengue-endemic regions... - B-cell responses during primary and secondary dengue virus infections in humansAnuja Mathew
Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
J Infect Dis 204:1514-22. 2011..Our data suggest that the minor populations of serotype-cross-reactive B cells generated by primary DENV infection are preferentially expanded during secondary DENV infection... - Cross-reactivity and expansion of dengue-specific T cells during acute primary and secondary infections in humansHeather Friberg
Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01655, USA
Sci Rep 1:51. 2011..These data confirm marked T cell activation and serotype-cross-reactivity during the febrile phase of dengue; however, A11-NS3(133)-specific responses did not correlate with prior antigenic exposure or current disease severity... - Analysis of repeat hospital admissions for dengue to estimate the frequency of third or fourth dengue infections resulting in admissions and dengue hemorrhagic fever, and serotype sequencesRobert V Gibbons
Department of Virology, United States Army Medical Component Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
Am J Trop Med Hyg 77:910-3. 2007..We document new dengue serotype infection sequences leading to DHF of 1-4, 2-3, 3-1, and 3-4...