Larry Squire

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Structure and function of declarative and nondeclarative memory systems
    L R Squire
    Veterans Affairs Medical Center, San Diego, La Jolla, CA 92161, USA
    Proc Natl Acad Sci U S A 93:13515-22. 1996
  2. ncbi request reprint The medial temporal lobe
    Larry R Squire
    Veterans Affairs Healthcare System, San Diego, California 92161, USA
    Annu Rev Neurosci 27:279-306. 2004
  3. pmc Recognition memory and the medial temporal lobe: a new perspective
    Larry R Squire
    Veterans Affairs Medical Center 116A, 3350 La Jolla Village Drive, San Diego, California 92161, USA
    Nat Rev Neurosci 8:872-83. 2007
  4. pmc Neuroscience. Rapid consolidation
    Larry R Squire
    VA Medical Center, San Diego, CA 92161, USA
    Science 316:57-8. 2007
  5. ncbi request reprint Memory systems of the brain: a brief history and current perspective
    Larry R Squire
    Veterans Affairs Healthcare System, San Diego, CA 92161, USA
    Neurobiol Learn Mem 82:171-7. 2004
  6. pmc Role of the hippocampus in remembering the past and imagining the future
    Larry R Squire
    Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    Proc Natl Acad Sci U S A 107:19044-8. 2010
  7. pmc The cognitive neuroscience of human memory since H.M
    Larry R Squire
    Veterans Affairs Healthcare System, San Diego, California 92161, USA
    Annu Rev Neurosci 34:259-88. 2011
  8. pmc The neuroscience of remote memory
    Larry R Squire
    Veterans Affairs Medical Center 116A, 3550 La Jolla Village Drive, San Diego, CA 92161, USA
    Curr Opin Neurobiol 17:185-96. 2007
  9. pmc Lost forever or temporarily misplaced? The long debate about the nature of memory impairment
    Larry R Squire
    Veterans Affairs Medical Center, Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
    Learn Mem 13:522-9. 2006
  10. pmc Impaired auditory recognition memory in amnesic patients with medial temporal lobe lesions
    L R Squire
    Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    Learn Mem 8:252-6. 2001

Research Grants

  1. MEMORY SYSTEMS OF THE MAMMALIAN BRAIN
    Larry Squire; Fiscal Year: 2004
  2. MEMORY AS AFFECTED BY AGING, DISEASE AND ECT
    Larry Squire; Fiscal Year: 1980
  3. MEMORY SYSTEMS OF THE MAMMALIAN BRAIN
    Larry Squire; Fiscal Year: 2009

Collaborators

Detail Information

Publications68

  1. pmc Structure and function of declarative and nondeclarative memory systems
    L R Squire
    Veterans Affairs Medical Center, San Diego, La Jolla, CA 92161, USA
    Proc Natl Acad Sci U S A 93:13515-22. 1996
    ....
  2. ncbi request reprint The medial temporal lobe
    Larry R Squire
    Veterans Affairs Healthcare System, San Diego, California 92161, USA
    Annu Rev Neurosci 27:279-306. 2004
    ....
  3. pmc Recognition memory and the medial temporal lobe: a new perspective
    Larry R Squire
    Veterans Affairs Medical Center 116A, 3350 La Jolla Village Drive, San Diego, California 92161, USA
    Nat Rev Neurosci 8:872-83. 2007
    ..We also indicate ways in which the functions of the medial temporal lobe structures are different, and suggest that these structures work together in a cooperative and complementary way...
  4. pmc Neuroscience. Rapid consolidation
    Larry R Squire
    VA Medical Center, San Diego, CA 92161, USA
    Science 316:57-8. 2007
  5. ncbi request reprint Memory systems of the brain: a brief history and current perspective
    Larry R Squire
    Veterans Affairs Healthcare System, San Diego, CA 92161, USA
    Neurobiol Learn Mem 82:171-7. 2004
    ..This article traces the development of these ideas and provides a current perspective on how these brain systems operate to support behavior...
  6. pmc Role of the hippocampus in remembering the past and imagining the future
    Larry R Squire
    Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    Proc Natl Acad Sci U S A 107:19044-8. 2010
    ..The findings suggest that the capacity for imagining the future, like the capacity for remembering the remote past, is independent of the hippocampus...
  7. pmc The cognitive neuroscience of human memory since H.M
    Larry R Squire
    Veterans Affairs Healthcare System, San Diego, California 92161, USA
    Annu Rev Neurosci 34:259-88. 2011
    ....
  8. pmc The neuroscience of remote memory
    Larry R Squire
    Veterans Affairs Medical Center 116A, 3550 La Jolla Village Drive, San Diego, CA 92161, USA
    Curr Opin Neurobiol 17:185-96. 2007
    ..The available evidence tells a coherent story and leads to some straightforward conclusions about the neuroscience of remote memory...
  9. pmc Lost forever or temporarily misplaced? The long debate about the nature of memory impairment
    Larry R Squire
    Veterans Affairs Medical Center, Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
    Learn Mem 13:522-9. 2006
    ..This work provides a straightforward and illuminating perspective on the question and confirms the view that first emerged from less direct evidence...
  10. pmc Impaired auditory recognition memory in amnesic patients with medial temporal lobe lesions
    L R Squire
    Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    Learn Mem 8:252-6. 2001
    ..The findings show that auditory recognition, like recognition memory in other sensory modalities, is dependent on the medial temporal lobe...
  11. ncbi request reprint Retrograde amnesia
    L R Squire
    Veterans Affairs Healthcare System, San Diego, California 92161, USA
    Hippocampus 11:50-5. 2001
    ..It is therefore encouraging that many opportunities exist for moving beyond purely descriptive studies to studies that involve treatments or manipulations directed toward yielding information about mechanisms...
  12. pmc The legacy of patient H.M. for neuroscience
    Larry R Squire
    Veterans Affairs Healthcare System, San Diego, CA 92161, USA
    Neuron 61:6-9. 2009
    ..Work with H.M. established fundamental principles about how memory functions are organized in the brain...
  13. pmc Experience-dependent eye movements reflect hippocampus-dependent (aware) memory
    Christine N Smith
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 28:12825-33. 2008
    ....
  14. pmc Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis
    Linda K McEvoy
    Department of Radiology, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
    Radiology 259:834-43. 2011
    ..To assess whether single-time-point and longitudinal volumetric magnetic resonance (MR) imaging measures provide predictive prognostic information in patients with amnestic mild cognitive impairment (MCI)...
  15. pmc Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats
    Sebastian Jessberger
    Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, California 92037, USA
    Learn Mem 16:147-54. 2009
    ....
  16. pmc Impaired remote spatial memory after hippocampal lesions despite extensive training beginning early in life
    Robert E Clark
    Veterans Affairs Medical Center, San Diego, California, USA
    Hippocampus 15:340-6. 2005
    ..Possible reasons for these findings are discussed in the context of the specific performance requirements of the water maze task...
  17. pmc Item memory, source memory, and the medial temporal lobe: concordant findings from fMRI and memory-impaired patients
    Jeffrey J Gold
    Veterans Affairs Medical Center, San Diego, CA 92161, USA
    Proc Natl Acad Sci U S A 103:9351-6. 2006
    ..Together, the findings suggest that medial temporal lobe structures broadly support recognition memory function and that item memory and source memory similarly depend on these structures...
  18. pmc The hippocampus and spatial memory: findings with a novel modification of the water maze
    Robert E Clark
    Veterans Affairs Medical Center, San Diego, California 92161, USA
    J Neurosci 27:6647-54. 2007
    ..These results indicate that impaired performance in the water maze after hippocampal damage reflects more than a loss of spatial information...
  19. pmc Reversible hippocampal lesions disrupt water maze performance during both recent and remote memory tests
    Nicola J Broadbent
    Department of Psychiatry, University of California, San Diego, California 92093, USA
    Learn Mem 13:187-91. 2006
    ..What determines whether remote spatial memory is preserved or impaired following disruption of hippocampal function appears to be the type of task used to assess spatial memory, not the method used to disrupt the hippocampus...
  20. pmc Single-item memory, associative memory, and the human hippocampus
    Jeffrey J Gold
    Veterans Affairs Medical Center, San Diego, California 92161, USA
    Learn Mem 13:644-9. 2006
    ....
  21. pmc Intact visual discrimination of complex and feature-ambiguous stimuli in the absence of perirhinal cortex
    Daniel A Levy
    Veterans Affairs Healthcare System, San Diego, California 92161, USA
    Learn Mem 12:61-6. 2005
    ..quot; These findings indicate that perirhinal cortex is not needed for visual perception across a wide range of visual perceptual tasks...
  22. pmc The fate of old memories after medial temporal lobe damage
    Peter J Bayley
    Department of Psychiatry, University of California, San Diego, California 92093, USA
    J Neurosci 26:13311-7. 2006
    ..The findings emphasize the difference in the extent of retrograde amnesia associated with hippocampal lesions and large MTL lesions...
  23. ncbi request reprint Anterograde amnesia and temporally graded retrograde amnesia for a nonspatial memory task after lesions of hippocampus and subiculum
    Robert E Clark
    Departments of Psychiatry, Neurosciences, and Psychology, University of California, La Jolla, California 92993, USA
    J Neurosci 22:4663-9. 2002
    ..The results show the importance of the hippocampus and related structures for nonspatial memory and also demonstrate the temporary role of these structures in long-term memory...
  24. pmc Medial temporal lobe amnesia: Gradual acquisition of factual information by nondeclarative memory
    Peter J Bayley
    Veterans Affairs Medical Center, San Diego, California 92161, USA
    J Neurosci 22:5741-8. 2002
    ..We suggest that E.P.'s learning depended on a process akin to perceptual learning and occurred directly within neocortex...
  25. pmc Quantifying medial temporal lobe damage in memory-impaired patients
    Jeffrey J Gold
    Department of Neurosciences, University of California, San Diego, California 92161, USA
    Hippocampus 15:79-85. 2005
    ..M. and W.H.), who also had reductions in hippocampal size of about 40%, we suggest that a volume reduction in this range likely indicates a nearly complete loss of hippocampal neurons...
  26. ncbi request reprint Semantic memory and the human hippocampus
    Joseph R Manns
    University of California, San Diego, La Jolla, California 92093, USA
    Neuron 38:127-33. 2003
    ..The results show that the hippocampal region supports semantic memory as well as episodic memory and that its role in the acquisition and storage of semantic knowledge is time limited...
  27. pmc Measuring recollection and familiarity in the medial temporal lobe
    John T Wixted
    Department of Psychology, University of California, San Diego, La Jolla, California 92093, USA
    Hippocampus 20:1195-205. 2010
    ..We suggest that an alternative method can be used to effectively investigate recollection and familiarity in the MTL, one that is valid whether recollection is a categorical or a continuous process...
  28. pmc The role of the human hippocampus in familiarity-based and recollection-based recognition memory
    John T Wixted
    Department of Psychology, University of California San Diego, La Jolla, CA 92093, USA
    Behav Brain Res 215:197-208. 2010
    ..These findings suggest that the functional organization of the medial temporal lobe is probably best understood in terms unrelated to the distinction between recollection and familiarity...
  29. pmc Functional amnesia: clinical description and neuropsychological profile of 10 cases
    Mark Kritchevsky
    Department of Neurosciences, University of California, San Diego, La Jolla, California 92093, USA
    Learn Mem 11:213-26. 2004
    ..The presentation of patients with functional amnesia is as variable as humankind's concept of what memory is and how it works...
  30. ncbi request reprint Recall and recognition are equally impaired in patients with selective hippocampal damage
    John T Wixted
    Department of Psychology, University of California at San Diego, La Jolla, California 92093, USA
    Cogn Affect Behav Neurosci 4:58-66. 2004
    ..Yonelinas et al. (2002) also analyzed remember/know judgments and ROC data in an effort to show that recollection is selectively impaired in patients, but these analyses also raise problems...
  31. pmc An animal model of recognition memory and medial temporal lobe amnesia: history and current issues
    Robert E Clark
    Veterans Affairs Medical Center, San Diego, 92161, USA
    Neuropsychologia 48:2234-44. 2010
    ..Attention is given to two prominent behavioral paradigms (delayed nonmatching to sample and tests of spontaneous novelty preference)...
  32. pmc Hippocampus and remote spatial memory in rats
    Robert E Clark
    Veterans Affairs Medical Center, San Diego, California, USA
    Hippocampus 15:260-72. 2005
    ..Alternatively, it is possible that in these tasks hippocampal lesions might produce an impairment in performance that prevents the expression of an otherwise intact spatial memory...
  33. pmc Object recognition memory and the rodent hippocampus
    Nicola J Broadbent
    Department of Psychiatry, University of California, La Jolla, California 92093, USA
    Learn Mem 17:5-11. 2010
    ..Hippocampal lesions produced moderate and reliable memory impairment. The results suggest that the hippocampus is important for object recognition memory...
  34. pmc Intact working memory for relational information after medial temporal lobe damage
    Annette Jeneson
    Department of Psychology, University of California, San Diego, California 92093, USA
    J Neurosci 30:13624-9. 2010
    ....
  35. pmc Recognition memory and the hippocampus: A test of the hippocampal contribution to recollection and familiarity
    Annette Jeneson
    Department of Psychology, University of California, San Diego, 92093, USA
    Learn Mem 17:63-70. 2010
    ..This pattern of performance suggests that the hippocampus supports both recollection and familiarity...
  36. pmc Activity in the medial temporal lobe predicts memory strength, whereas activity in the prefrontal cortex predicts recollection
    C Brock Kirwan
    Institute for Neural Computation, Department of Neurosciences, University of California, San Diego, San Diego, California 92093, USA
    J Neurosci 28:10541-8. 2008
    ..These findings suggest that activity in the medial temporal lobe is predictive of subsequent memory strength, whereas activity in prefrontal cortex is predictive of subsequent recollection...
  37. pmc In search of recollection and familiarity signals in the hippocampus
    Peter E Wais
    University of California, San Diego, La Jolla, CA, USA
    J Cogn Neurosci 22:109-23. 2010
    ..Similar results were obtained in the parahippocampal gyrus. Unlike in the medial temporal lobe, activation in prefrontal cortex increased differentially in association with source recollection...
  38. pmc Medial temporal lobe activity can distinguish between old and new stimuli independently of overt behavioral choice
    C Brock Kirwan
    Department of Psychiatry, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 106:14617-21. 2009
    ..Accordingly, activity in the medial temporal lobe can be modulated by the old/new status of stimuli and does not always track the behavioral response...
  39. pmc Robust habit learning in the absence of awareness and independent of the medial temporal lobe
    Peter J Bayley
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
    Nature 436:550-3. 2005
    ..The acquired knowledge was rigidly organized, and performance collapsed when the task format was altered...
  40. pmc Spatial memory, recognition memory, and the hippocampus
    Nicola J Broadbent
    Veterans Affairs Medical Center, San Diego, CA 92161, USA
    Proc Natl Acad Sci U S A 101:14515-20. 2004
    ..These findings show that the hippocampus is important for both spatial memory and recognition memory. However, spatial memory performance requires more hippocampal tissue than does recognition memory...
  41. pmc The hippocampus supports both the recollection and the familiarity components of recognition memory
    Peter E Wais
    Department of Psychology, University of California, San Diego, La Jolla, California 92093, USA
    Neuron 49:459-66. 2006
    ..These results suggest that the component processes that determine the shape of the ROC are operative in the absence of the hippocampus, and they argue against the idea that the hippocampus selectively supports the recollection process...
  42. pmc Failure to acquire new semantic knowledge in patients with large medial temporal lobe lesions
    Peter J Bayley
    Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
    Hippocampus 15:273-80. 2005
    ..Accordingly, the results raise the possibility that the acquisition of conscious (declarative) knowledge about the world cannot be supported by structures outside the MTL, even with extended exposure. Published 2004 Wiley-Liss, Inc...
  43. ncbi request reprint Successful recollection of remote autobiographical memories by amnesic patients with medial temporal lobe lesions
    Peter J Bayley
    University of California, San Diego, La Jolla, California 92093, USA
    Neuron 38:135-44. 2003
    ..A number of other considerations suggest that the neocortex ultimately supports the capacity for recollecting remote autobiographical memory...
  44. pmc Rats depend on habit memory for discrimination learning and retention
    Nicola J Broadbent
    Department of Psychiatry, University of California, La Jolla, California 92093, USA
    Learn Mem 14:145-51. 2007
    ..Considered together with related studies of humans and nonhuman primates, the findings suggest that different species will approach the same task in different ways...
  45. pmc Experience-dependent eye movements, awareness, and hippocampus-dependent memory
    Christine N Smith
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 26:11304-12. 2006
    ..The findings show that experience-dependent eye movements in response to altered scenes reflect conscious, declarative memory, and they support the link between aware memory, declarative memory, and hippocampus-dependent memory...
  46. pmc The anatomy of amnesia: neurohistological analysis of three new cases
    Jeffrey J Gold
    Veterans Affairs Medical Center, San Diego, California 92161, USA
    Learn Mem 13:699-710. 2006
    ..These findings illuminate several issues regarding the relation between diencephalic and medial temporal lobe amnesia, the status of recognition memory in amnesia, and the neuroanatomy of memory...
  47. pmc Impaired odor recognition memory in patients with hippocampal lesions
    Daniel A Levy
    Veterans Affairs Healthcare System, San Diego, California 92161, USA
    Learn Mem 11:794-6. 2004
    ..Olfactory recognition memory, similar to recognition memory in other sensory modalities, depends on the integrity of the hippocampal region...
  48. pmc Medial temporal lobe activity during retrieval of semantic memory is related to the age of the memory
    Christine N Smith
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 29:930-8. 2009
    ..The results support the idea that medial temporal lobe structures play a time-limited role in semantic memory...
  49. pmc Impaired visual and odor recognition memory span in patients with hippocampal lesions
    Daniel A Levy
    Veterans Affairs Healthcare System, San Diego, California 92161, USA
    Learn Mem 10:531-6. 2003
    ..The patients were impaired on all three tasks. We consider possible explanations for the difference between the findings for humans and rats, including the fact that olfactory function is particularly well-developed in rodents...
  50. pmc Losing memories overnight: a unique form of human amnesia
    Christine N Smith
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, United States
    Neuropsychologia 48:2833-40. 2010
    ....
  51. ncbi request reprint Recognition memory and the human hippocampus
    Joseph R Manns
    University of California, San Diego, La Jolla, CA 92093, USA
    Neuron 37:171-80. 2003
    ....
  52. pmc Neural correlates of knowledge: stable representation of stimulus associations across variations in behavioral performance
    Adam Messinger
    Systems Neurobiology Laboratories, Salk Institute, La Jolla, California 92037, USA
    Neuron 48:359-71. 2005
    ..These neurons appear to represent memorized stimulus associations that are stable across variations in behavioral performance. In addition, many neurons (74%) were modulated by the spatial arrangement of the stimuli in the display...
  53. pmc Declarative memory, awareness, and transitive inference
    Christine Smith
    Institute for Neural Computation, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 25:10138-46. 2005
    ..The findings indicate that awareness is critical for robust performance on tests of transitive inference and support the view that awareness of what is learned is a fundamental characteristic of declarative memory...
  54. pmc Spatial memory and the human hippocampus
    Yael Shrager
    Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 104:2961-6. 2007
    ..We conclude that damage to the hippocampus does not selectively impair viewpoint-independent spatial memory. Rather, hippocampal damage impairs memory as the memory load increases...
  55. pmc The neuroanatomy of remote memory
    Peter J Bayley
    University of California, San Diego, La Jolla, California 92093, USA
    Neuron 46:799-810. 2005
    ....
  56. pmc Intact visual perception in memory-impaired patients with medial temporal lobe lesions
    Yael Shrager
    Department of Neurosciences, University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 26:2235-40. 2006
    ..Furthermore, the results support the principle that the ability to acquire new memories is a distinct cerebral function, dissociable from other perceptual and cognitive functions...
  57. ncbi request reprint Semantic knowledge in patient H.M. and other patients with bilateral medial and lateral temporal lobe lesions
    Heike Schmolck
    Department of Psychiatry, University of California, La Jolla 92093, USA
    Hippocampus 12:520-33. 2002
    ..Considering that H.M.'s lesion, both medially and laterally, is less extensive than the lesions in these other patients, it appears unlikely that his shortcomings in language production are related to his temporal lobe lesion...
  58. pmc Activity in both hippocampus and perirhinal cortex predicts the memory strength of subsequently remembered information
    Yael Shrager
    Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA
    Neuron 59:547-53. 2008
    ..This finding suggests that both structures cooperate during learning to determine the memory strength of what is being learned...
  59. pmc Neural basis of the cognitive map: path integration does not require hippocampus or entorhinal cortex
    Yael Shrager
    Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 105:12034-8. 2008
    ..When demands on long-term memory were increased, patients were impaired. Thus, in humans, the hippocampus and entorhinal cortex are not essential for path integration...
  60. pmc Working memory and the organization of brain systems
    Yael Shrager
    University of California, San Diego, La Jolla, California 92093, USA
    J Neurosci 28:4818-22. 2008
    ..These findings support the conclusion that working memory (active maintenance) is intact after medial temporal lobe damage...
  61. ncbi request reprint Genetics of childhood disorders: XLIX. Learning and memory, part 2: multiple memory systems
    Stuart Zola
    Department of Psychiatry, Emory University and VA Medical Center, Atlanta, GA, USA
    J Am Acad Child Adolesc Psychiatry 42:504-6. 2003
  62. pmc An analysis of calendar performance in two autistic calendar savants
    Daniel P Kennedy
    Department of Neurosciences, University of California San Diego, La Jolla, California 92093, USA
    Learn Mem 14:533-8. 2007
    ..In view of the fact that there are only 14 possible annual calendars, we suggest that both savants worked by memorizing these 14 possible calendar arrangements...
  63. ncbi request reprint The importance of awareness for eyeblink conditioning is conditional: theoretical comment on Bellebaum and Daum (2004)
    Robert E Clark
    Veterans Affairs Medical Center, San Diego, CA 92161, USA
    Behav Neurosci 118:1466-8. 2004
    ....
  64. pmc Acquisition of differential delay eyeblink classical conditioning is independent of awareness
    Christine N Smith
    Institute for Neural Computation, University of California, San Diego, CA, USA
    Behav Neurosci 119:78-86. 2005
    ..Awareness of stimulus contingencies is not required for differential delay eyeblink conditioning when simple conditioned stimuli are used...
  65. pmc Hippocampal damage equally impairs memory for single items and memory for conjunctions
    Craig E L Stark
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland, USA
    Hippocampus 13:281-92. 2003
    ..We discuss our findings in the light of the work by Kroll et al. (1996) and other recent neuropsychological, electrophysiological, and neuroimaging studies of hippocampal function and single-item and associative memory...
  66. pmc The neuroanatomy of very remote memory
    Larry R Squire
    Lancet Neurol 5:112-3. 2006
  67. pmc Recognition memory for single items and for associations is similarly impaired following damage to the hippocampal region
    Craig E L Stark
    Departments of Psychological and Brain Sciences and of Neuroscience, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Learn Mem 9:238-42. 2002
    ..Thus, the associative condition was not disproportionally difficult for the amnesic patients. These results are consistent with the idea that the hippocampus is similarly involved in single-item and associative memory...
  68. pmc Detailed recollection of remote autobiographical memory after damage to the medial temporal lobe
    C Brock Kirwan
    Institute for Neural Computation, Departments of Psychiatry, Neurosciences, and Psychology, University of California at San Diego, La Jolla, CA 92093
    Proc Natl Acad Sci U S A 105:2676-80. 2008
    ..Impaired remote autobiographical memory, which has sometimes been reported with this and other tests, is likely caused by significant damage outside the medial temporal lobe...

Research Grants17

  1. MEMORY SYSTEMS OF THE MAMMALIAN BRAIN
    Larry Squire; Fiscal Year: 2004
    ..A second key component of our program is our new work with rats, which is conceptually closely related to our work with humans. ..
  2. MEMORY AS AFFECTED BY AGING, DISEASE AND ECT
    Larry Squire; Fiscal Year: 1980
    ..A final objective is to determine in animal studies the relationship between current parameters of electroconvulsive shock (ECS) and amnesia...
  3. MEMORY SYSTEMS OF THE MAMMALIAN BRAIN
    Larry Squire; Fiscal Year: 2009
    ..A second key component of the work is the close conceptual relationship between the rodent program and the work with humans. ..