T C Squier

Summary

Affiliation: University of Kansas
Country: USA

Publications

  1. ncbi Protein oxidation and age-dependent alterations in calcium homeostasis
    T C Squier
    Biochemistry and Biophysics Section, Department of Molecular Bioscience, University of Kansas, Lawrence, KS 66045 2106, USA
    Front Biosci 5:D504-26. 2000
  2. ncbi Oxidative stress and protein aggregation during biological aging
    T C Squier
    Department of Molecular Biosciences, Biochemistry and Biophysics Section, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045 7534, USA
    Exp Gerontol 36:1539-50. 2001
  3. ncbi Phosphorylation of phospholamban by cAMP-dependent protein kinase enhances interactions between Ca-ATPase polypeptide chains in cardiac sarcoplasmic reticulum membranes
    S Negash
    Department of Biochemistry, University of Kansas, Lawrence 66045 2106, USA
    Biochemistry 35:11247-59. 1996
  4. ncbi Oxidatively modified calmodulin binds to the plasma membrane Ca-ATPase in a nonproductive and conformationally disordered complex
    J Gao
    Biochemistry and Biophysics Section, Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045, USA
    Biophys J 80:1791-801. 2001
  5. ncbi Age-related decrease in brain synaptic membrane Ca2+-ATPase in F344/BNF1 rats
    A Zaidi
    Department of Pharmacology and Toxicology, University of Kansas, Lawrence 66045, USA
    Neurobiol Aging 19:487-95. 1998
  6. ncbi Oligomeric interactions between phospholamban molecules regulate Ca-ATPase activity in functionally reconstituted membranes
    Q Yao
    Biochemistry and Biophysics Section, Department of Molecular Biosciences, University of Kansas, Lawrence 66045-2106, USA
    Biochemistry 40:6406-13. 2001
  7. ncbi Calcium-dependent stabilization of the central sequence between Met(76) and Ser(81) in vertebrate calmodulin
    Z Qin
    Biochemistry and Biophysics Section, Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045, USA
    Biophys J 81:2908-18. 2001
  8. ncbi Mutation of Tyr138 disrupts the structural coupling between the opposing domains in vertebrate calmodulin
    H Sun
    Department of Molecular Biosciences, University of Kansas, Lawrence 66045-2106, USA
    Biochemistry 40:9605-17. 2001
  9. ncbi Substrate binding stabilizes S-adenosylhomocysteine hydrolase in a closed conformation
    D Yin
    Department of Pharmaceutical Chemistry and Biochemistry and Biophysics Section, Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045, USA
    Biochemistry 39:9811-8. 2000

Collaborators

  • M L Michaelis
  • D Yin
  • J Li
  • J Gao
  • H Sun
  • Q Yao
  • Z Qin
  • D J Bigelow
  • L T Chen
  • A Zaidi
  • S Negash
  • L A Coffeen
  • M A Shea
  • K Brungardt
  • Y Yao

Detail Information

Publications9

  1. ncbi Protein oxidation and age-dependent alterations in calcium homeostasis
    T C Squier
    Biochemistry and Biophysics Section, Department of Molecular Bioscience, University of Kansas, Lawrence, KS 66045 2106, USA
    Front Biosci 5:D504-26. 2000
    ..Thus, a diminished ability to efficiently generate cellular ATP may ultimately underlie the loss of calcium homeostasis and cellular function during aging...
  2. ncbi Oxidative stress and protein aggregation during biological aging
    T C Squier
    Department of Molecular Biosciences, Biochemistry and Biophysics Section, University of Kansas, 1200 Sunnyside Avenue, Lawrence, KS 66045 7534, USA
    Exp Gerontol 36:1539-50. 2001
    ....
  3. ncbi Phosphorylation of phospholamban by cAMP-dependent protein kinase enhances interactions between Ca-ATPase polypeptide chains in cardiac sarcoplasmic reticulum membranes
    S Negash
    Department of Biochemistry, University of Kansas, Lawrence 66045 2106, USA
    Biochemistry 35:11247-59. 1996
    ..We suggest that altered interactions between Ca-ATPase polypeptide chains and PLB serves to modulate the activation barrier associated with calcium activation of the Ca-ATPase in cardiac SR membranes...
  4. ncbi Oxidatively modified calmodulin binds to the plasma membrane Ca-ATPase in a nonproductive and conformationally disordered complex
    J Gao
    Biochemistry and Biophysics Section, Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045, USA
    Biophys J 80:1791-801. 2001
    ....
  5. ncbi Age-related decrease in brain synaptic membrane Ca2+-ATPase in F344/BNF1 rats
    A Zaidi
    Department of Pharmacology and Toxicology, University of Kansas, Lawrence 66045, USA
    Neurobiol Aging 19:487-95. 1998
    ....
  6. ncbi Oligomeric interactions between phospholamban molecules regulate Ca-ATPase activity in functionally reconstituted membranes
    Q Yao
    Biochemistry and Biophysics Section, Department of Molecular Biosciences, University of Kansas, Lawrence 66045-2106, USA
    Biochemistry 40:6406-13. 2001
    ....
  7. ncbi Calcium-dependent stabilization of the central sequence between Met(76) and Ser(81) in vertebrate calmodulin
    Z Qin
    Biochemistry and Biophysics Section, Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045, USA
    Biophys J 81:2908-18. 2001
    ....
  8. ncbi Mutation of Tyr138 disrupts the structural coupling between the opposing domains in vertebrate calmodulin
    H Sun
    Department of Molecular Biosciences, University of Kansas, Lawrence 66045-2106, USA
    Biochemistry 40:9605-17. 2001
    ....
  9. ncbi Substrate binding stabilizes S-adenosylhomocysteine hydrolase in a closed conformation
    D Yin
    Department of Pharmaceutical Chemistry and Biochemistry and Biophysics Section, Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas 66045, USA
    Biochemistry 39:9811-8. 2000
    ..Thus, the catalytic and NAD(+) binding domains are stabilized to form a closed active site through interactions with the substrate prior to substrate oxidation...