Research Topics
| S R SponheimSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
A dimensional model of personality disorder: incorporating DSM Cluster A characteristicsJennifer L Tackett
Department of Psychology, University of Toronto, Toronto, Canada
J Abnorm Psychol 117:454-9. 2008..This study has implications for the consideration of a dimensional model of personality disorder in DSM-V by offering a more comprehensive structural model that builds on previous work in this area...
Anhedonia as a phenotype for the Val158Met COMT polymorphism in relatives of patients with schizophreniaAnna R Docherty
Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
J Abnorm Psychol 117:788-98. 2008..Findings suggest that anhedonia is manifest in individuals who carry genetic liability for schizophrenia and is associated with the Val(158)Met polymorphism of the COMT gene...
Sensitivity and specificity of select biological indices in characterizing psychotic patients and their relativesScott R Sponheim
Veterans Affairs Medical Center, 116B One Veterans Drive, Minneapolis, MN 55417, USA
Schizophr Res 63:27-38. 2003..Although studies have detailed biological abnormalities in schizophrenia patients and their first-degree biological relatives, few studies have directly compared the utility of biological indices in these individuals...
Evidence of disrupted functional connectivity in the brain after combat-related blast injuryScott R Sponheim
Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Neuroimage 54:S21-9. 2011..post-traumatic stress and depression) and commonly prescribed medications. Results provide evidence for poor coordination of frontal neural function after blast injury that may be the consequence of damaged anterior white matter tracts...
Proverb interpretation in schizophrenia: the significance of symptomatology and cognitive processesScott R Sponheim
Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Schizophr Res 65:117-23. 2003....
Verbal memory processes in schizophrenia patients and biological relatives of schizophrenia patients: intact implicit memory, impaired explicit recollectionScott R Sponheim
Veterans Affairs Medical Center, 116B, One Veterans Drive, Minneapolis, MN 55417, USA
Schizophr Res 71:339-48. 2004..Findings are consistent with impaired explicit recollection of verbal material, but intact implicit verbal memory in schizophrenia patients and biological relatives of schizophrenia patients...
Neural anomalies during sustained attention in first-degree biological relatives of schizophrenia patientsScott R Sponheim
Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
Biol Psychiatry 60:242-52. 2006..We sought to detail functional brain abnormalities associated with sustained attention (i.e., vigilance) in individuals with genetic liability for schizophrenia...
Cognitive deficits in recent-onset and chronic schizophreniaS R Sponheim
VA Medical Center, One Veterans Drive, Minneapolis, MN 55417, United States
J Psychiatr Res 44:421-8. 2010..Also, worse recall of material in episodic memory was associated with greater length of illness. Nevertheless, findings indicate that nearly all cognitive deficits are comparably impaired across recent-onset and chronic schizophrenia...
Using biological indices to classify schizophrenia and other psychotic patientsS R Sponheim
Department of Psychology, University of Minnesota, Minneapolis, MN, USA
Schizophr Res 50:139-50. 2001..Multivariate biologically defined clusters may offer an advantage over DSM-IV classification when examining nosology and etiology of psychotic disorders...
Neural anomalies during visual search in schizophrenia patients and unaffected siblings of schizophrenia patientsNicholas D Davenport
Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
Schizophr Res 82:15-26. 2006..While the latter may reflect neural mechanisms predisposing performance deficits on attentional tasks, the former may reflect compensatory processes present in unaffected relatives of schizophrenia patients...
The dot pattern expectancy task: reliability and replication of deficits in schizophreniaJessica A H Jones
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
Psychol Assess 22:131-41. 2010....
Genetic and disorder-specific aspects of resting state EEG abnormalities in schizophreniaNoah C Venables
Department of Psychology, University of Minnesota, Twin Cities, Minneapolis, MN, USA
Schizophr Bull 35:826-39. 2009..Low-frequency resting state EEG anomalies in schizophrenia may relate to disorder-specific pathophysiology in schizophrenia and the influence of the COMT gene on tonic dopamanergic function...
Elevated nailfold plexus visibility aggregates in families and is associated with a specific negative symptom pattern in schizophreniaJOHN P VUCHETICH
Department of Psychiatry, University of Minnesota, Minneapolis, MN, United States
Psychiatry Res 160:30-7. 2008..However, relatives of low NPV patients scored significantly higher on scales of positive symptom schizotypy. Overall, these results support the hypothesis that high NPV is a marker of risk for a distinct subtype of schizophrenia...
Personality in relation to genetic liability for schizophrenia and bipolar disorder: differential associations with the COMT Val 108/158 Met polymorphismAmy L Silberschmidt
Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, United States
Schizophr Res 100:316-24. 2008....
Evaluation context impacts neuropsychological performance of OEF/OIF veterans with reported combat-related concussionNathaniel W Nelson
Minneapolis VA Medical Center, MN, USA
Arch Clin Neuropsychol 25:713-23. 2010..Results highlight the importance of effort assessment among OEF/OIF and other veterans with concussion history, particularly in forensic contexts...
Synchronous neural interactions assessed by magnetoencephalography: a functional biomarker for brain disordersApostolos P Georgopoulos
Brain Sciences Center, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
J Neural Eng 4:349-55. 2007....
Predictors of emotional distress reported by soldiers in the combat zoneAmanda G Ferrier-Auerbach
Minneapolis VA Medical Center, Minneapolis, MN, United States
J Psychiatr Res 44:470-6. 2010....
An auditory processing abnormality specific to liability for schizophreniaRachel B Force
Department of Psychology, University of Minnesota, Twin Cities, United States
Schizophr Res 103:298-310. 2008..Reduced N1 responses reflective of early auditory processing abnormalities are suggestive of a marker of genetic liability for schizophrenia and may serve as an endophenotype for the disorder...
Differential association of the COMT Val158Met polymorphism with clinical phenotypes in schizophrenia and bipolar disorderVina M Goghari
Department of Psychology, University of Minnesota, Twin Cities, United States
Schizophr Res 103:186-91. 2008..Lifetime symptomatology may be particularly useful in determining the relationship between genes and clinical phenotypes across mental disorders...
Does cognition predict community function only in schizophrenia?: a study of schizophrenia patients, bipolar affective disorder patients, and community control subjectsJoAn R Laes
Department of Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN 55455 USA
Schizophr Res 84:121-31. 2006..Therefore, unlike schizophrenia patients who may fail to process verbally mediated material, bipolar patients' difficulty with logical approaches to problems in daily living may have the greatest impact on their community function...
Generalized cognitive dysfunction, symptomatology, and specific cognitive processes in relation to functioning of schizophrenia patientsScott R Sponheim
Schizophr Res 64:191-3. 2003
Divergent backward masking performance in schizophrenia and bipolar disorder: association with COMTVina M Goghari
Department of Psychology, University of Minnesota, Twin Cities, Minnesota, USA
Am J Med Genet B Neuropsychiatr Genet 147:223-7. 2008..The COMT Met allele may be associated with deficits in schizophrenia that are unrelated to neural systems supporting sustained attention or working memory...
Functional neuroanatomy of the human near/far response to blur cues: eye-lens accommodation/vergence to point targets varying in depthHans O Richter
Department of Ophthalmology, Karolinska Institute, Huddinge, Sweden
Eur J Neurosci 20:2722-32. 2004....
