Matthew Spite

Summary

Affiliation: University of Louisville
Country: USA

Publications

  1. pmc Proresolution therapy for the treatment of delayed healing of diabetic wounds
    Yunan Tang
    Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, Kentucky, USA
    Diabetes 62:618-27. 2013
  2. pmc Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity
    Matthew Spite
    Division of Cardiovascular Medicine, Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
    J Immunol 187:1942-9. 2011
  3. pmc Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese-diabetic mice
    Jason Hellmann
    Diabetes and Obesity Center, University of Louisville, Louisville, KY 40202, USA
    FASEB J 25:2399-407. 2011
  4. pmc Increased saturated fatty acids in obesity alter resolution of inflammation in part by stimulating prostaglandin production
    Jason Hellmann
    Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
    J Immunol 191:1383-92. 2013
  5. pmc Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype
    Brian E Sansbury
    Institute of Molecular Cardiology, Department of Medicine, University of Louisville, Louisville, KY 40202, USA
    Circ Res 111:1176-89. 2012
  6. pmc Proresolving lipid mediators and diabetic wound healing
    Jason Hellmann
    Division of Cardiovascular Medicine, Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Curr Opin Endocrinol Diabetes Obes 19:104-8. 2012
  7. pmc Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes
    Matthew Spite
    Institute of Molecular Cardiology, University of Louisville, Louisville, KY 40202, USA
    Biochem J 405:95-105. 2007
  8. pmc Deciphering the role of n-3 polyunsaturated fatty acid-derived lipid mediators in health and disease
    Matthew Spite
    Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Proc Nutr Soc 72:441-50. 2013
  9. doi Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids
    Michael J Zhang
    Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Annu Rev Nutr 32:203-27. 2012
  10. pmc Aldose reductase-catalyzed reduction of aldehyde phospholipids
    Sanjay Srivastava
    Institute of Molecular Cardiology, Department of Medicine, 580 S Preston St, University of Louisville, Louisville, KY 40202, USA
    J Biol Chem 279:53395-406. 2004

Collaborators

Detail Information

Publications12

  1. pmc Proresolution therapy for the treatment of delayed healing of diabetic wounds
    Yunan Tang
    Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, Kentucky, USA
    Diabetes 62:618-27. 2013
    ....
  2. pmc Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity
    Matthew Spite
    Division of Cardiovascular Medicine, Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
    J Immunol 187:1942-9. 2011
    ....
  3. pmc Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese-diabetic mice
    Jason Hellmann
    Diabetes and Obesity Center, University of Louisville, Louisville, KY 40202, USA
    FASEB J 25:2399-407. 2011
    ..These results suggest that stimulating resolution with the endogenous proresolving mediator RvD1 could provide a novel therapeutic strategy for treating obesity-induced diabetes...
  4. pmc Increased saturated fatty acids in obesity alter resolution of inflammation in part by stimulating prostaglandin production
    Jason Hellmann
    Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
    J Immunol 191:1383-92. 2013
    ....
  5. pmc Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype
    Brian E Sansbury
    Institute of Molecular Cardiology, Department of Medicine, University of Louisville, Louisville, KY 40202, USA
    Circ Res 111:1176-89. 2012
    ..Nevertheless, the metabolic effects of increasing eNOS levels have not been studied...
  6. pmc Proresolving lipid mediators and diabetic wound healing
    Jason Hellmann
    Division of Cardiovascular Medicine, Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Curr Opin Endocrinol Diabetes Obes 19:104-8. 2012
    ..Here, we review recent advances in the area of resolution and diabetes and highlight the potential of novel proresolving strategies for promoting wound healing in diabetes...
  7. pmc Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes
    Matthew Spite
    Institute of Molecular Cardiology, University of Louisville, Louisville, KY 40202, USA
    Biochem J 405:95-105. 2007
    ....
  8. pmc Deciphering the role of n-3 polyunsaturated fatty acid-derived lipid mediators in health and disease
    Matthew Spite
    Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Proc Nutr Soc 72:441-50. 2013
    ....
  9. doi Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids
    Michael J Zhang
    Diabetes and Obesity Center, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Annu Rev Nutr 32:203-27. 2012
    ..In this review, we describe the endogenous biosynthesis and immunomodulatory actions of resolvins and highlight their emerging roles in health and disease...
  10. pmc Aldose reductase-catalyzed reduction of aldehyde phospholipids
    Sanjay Srivastava
    Institute of Molecular Cardiology, Department of Medicine, 580 S Preston St, University of Louisville, Louisville, KY 40202, USA
    J Biol Chem 279:53395-406. 2004
    ..This metabolism may be a critical regulator of the pro-inflammatory and immunogenic effects of oxidized phospholipids...
  11. pmc Aldose reductase protects against early atherosclerotic lesion formation in apolipoprotein E-null mice
    Sanjay Srivastava
    Diabetes and Obesity Center, Institute of Molecular Cardiology, Division of Cardiovascular Medicine, Department of Medicine, University of Louisville, Louisville, KY 40202, USA
    Circ Res 105:793-802. 2009
    ..Products of lipid oxidation, particularly aldehydes, stimulate cytokine production and enhance monocyte adhesion; however, their contribution to atherosclerotic lesion formation remains unclear...
  12. pmc Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases
    Matthew Spite
    Diabetes and Obesity Center, Institute of Molecular Cardiology and Department of Microbiology and Immunology, University of Louisville, Louisville, KY 40202, USA
    Cell Metab 19:21-36. 2014
    ..Here, we review evidence that the failure of resolution programs contributes to metabolic diseases and that SPMs may play pivotal roles in their resolution...