J A Spertus

Summary

Affiliation: University of Missouri-Kansas City
Country: USA

Publications

  1. doi request reprint Effect of PCI on quality of life in patients with stable coronary disease
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    N Engl J Med 359:677-87. 2008
  2. pmc Factors associated with racial differences in myocardial infarction outcomes
    John A Spertus
    Mid America Heart Institute of Saint Luke s Hospital and University of Missouri Kansas City, Kansas City, Missouri, USA
    Ann Intern Med 150:314-24. 2009
  3. doi request reprint Frequency, predictors, and consequences of crossing over to revascularization within 12 months of randomization to optimal medical therapy in the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial
    John A Spertus
    Department of Cardiovascular Research, Saint Luke s Mid America Heart Institute, University of Missouri Kansas City, Kansas City, MO, USA
    Circ Cardiovasc Qual Outcomes 6:409-18. 2013
  4. pmc Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysis
    James B Wetmore
    Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS, USA
    BMC Res Notes 4:542. 2011
  5. pmc Assessing responsiveness of generic and specific health related quality of life measures in heart failure
    Dean T Eurich
    Institute of Health Economics, Edmonton, Alberta, Canada
    Health Qual Life Outcomes 4:89. 2006
  6. pmc Testing the performance of the ENRICHD Social Support Instrument in cardiac patients
    Joseph Vaglio
    Mid America Heart Institute at St Lukes Hospital, Kansas City, MO, USA
    Health Qual Life Outcomes 2:24. 2004
  7. pmc Factors influencing patient willingness to participate in genetic research after a myocardial infarction
    David E Lanfear
    Henry Ford Hospital, Heart and Vascular Institute, Detroit, Michigan, 48202, USA
    Genome Med 3:39. 2011
  8. pmc Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome
    Thomas M Morgan
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    BMC Med Genet 12:127. 2011
  9. pmc Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome
    Thomas M Morgan
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    BMC Med Genet 9:66. 2008
  10. pmc Increased mortality among survivors of myocardial infarction with kidney dysfunction: the contribution of gaps in the use of guideline-based therapies
    Pamela N Peterson
    Denver Health Medical Center, Denver, Colorado, USA
    BMC Cardiovasc Disord 9:29. 2009

Collaborators

Detail Information

Publications108 found, 100 shown here

  1. doi request reprint Effect of PCI on quality of life in patients with stable coronary disease
    William S Weintraub
    Christiana Care Health System, Newark, DE 19718, USA
    N Engl J Med 359:677-87. 2008
    ..It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease...
  2. pmc Factors associated with racial differences in myocardial infarction outcomes
    John A Spertus
    Mid America Heart Institute of Saint Luke s Hospital and University of Missouri Kansas City, Kansas City, Missouri, USA
    Ann Intern Med 150:314-24. 2009
    ..Little information is available about factors associated with racial differences across a broad spectrum of post-myocardial infarction outcomes, including patients' symptoms and quality of life...
  3. doi request reprint Frequency, predictors, and consequences of crossing over to revascularization within 12 months of randomization to optimal medical therapy in the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial
    John A Spertus
    Department of Cardiovascular Research, Saint Luke s Mid America Heart Institute, University of Missouri Kansas City, Kansas City, MO, USA
    Circ Cardiovasc Qual Outcomes 6:409-18. 2013
    ..The predictors and outcomes of patients who crossed over from OMT to revascularization are unknown...
  4. pmc Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysis
    James B Wetmore
    Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS, USA
    BMC Res Notes 4:542. 2011
    ..abstract:..
  5. pmc Assessing responsiveness of generic and specific health related quality of life measures in heart failure
    Dean T Eurich
    Institute of Health Economics, Edmonton, Alberta, Canada
    Health Qual Life Outcomes 4:89. 2006
    ..We compared the relative responsiveness of generic and heart failure specific HRQL instruments, as measured both by common psychometric indices and by external clinical criteria...
  6. pmc Testing the performance of the ENRICHD Social Support Instrument in cardiac patients
    Joseph Vaglio
    Mid America Heart Institute at St Lukes Hospital, Kansas City, MO, USA
    Health Qual Life Outcomes 2:24. 2004
    ..Validity and reliability of the ESSI, however, has not been formally tested in patients undergoing percutaneous coronary intervention (PCI)...
  7. pmc Factors influencing patient willingness to participate in genetic research after a myocardial infarction
    David E Lanfear
    Henry Ford Hospital, Heart and Vascular Institute, Detroit, Michigan, 48202, USA
    Genome Med 3:39. 2011
    ..We sought to identify characteristics associated with genetic consent in a myocardial infarction (MI) registry...
  8. pmc Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome
    Thomas M Morgan
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    BMC Med Genet 12:127. 2011
    ..Genome-wide association studies (GWAS) have identified new candidate genes for the occurrence of acute coronary syndrome (ACS), but possible effects of such genes on survival following ACS have yet to be investigated...
  9. pmc Investigation of 89 candidate gene variants for effects on all-cause mortality following acute coronary syndrome
    Thomas M Morgan
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA
    BMC Med Genet 9:66. 2008
    ..Many candidate genes have been reported to be risk factors for acute coronary syndrome (ACS), but their impact on clinical prognosis following ACS is unknown...
  10. pmc Increased mortality among survivors of myocardial infarction with kidney dysfunction: the contribution of gaps in the use of guideline-based therapies
    Pamela N Peterson
    Denver Health Medical Center, Denver, Colorado, USA
    BMC Cardiovasc Disord 9:29. 2009
    ..We assessed the degree to which differences in guideline-based medical therapy for acute myocardial infarction (AMI) contribute to the higher mortality associated with kidney disease...
  11. pmc One-year health status outcomes of unstable angina versus myocardial infarction: a prospective, observational cohort study of ACS survivors
    Thomas M Maddox
    Denver VAMC University of Colorado Health Science Center, Denver, CO, USA
    BMC Cardiovasc Disord 7:28. 2007
    ..Little is known, however, about the health status outcomes (angina, physical function, and quality of life) of UA versus MI patients among survivors of an ACS hospitalization...
  12. pmc The impact of diabetes on one-year health status outcomes following acute coronary syndromes
    Pamela N Peterson
    Department of Medicine, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA
    BMC Cardiovasc Disord 6:41. 2006
    ..The objective of this study was to examine the association between diabetes and patients' health status outcomes one year after an acute coronary syndrome (ACS)...
  13. ncbi request reprint Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry
    John A Spertus
    MPH, Mid America Heart Institute, 4401 Wornall Rd, Kansas City, MO 64111
    Circulation 113:2803-9. 2006
    ..The rate and consequences of prematurely discontinuing thienopyridine therapy after DES placement for acute myocardial infarction (MI) are unknown...
  14. ncbi request reprint The Prospective Registry Evaluating Myocardial Infarction: Events and Recovery (PREMIER)--evaluating the impact of myocardial infarction on patient outcomes
    John A Spertus
    Mid America Heart Institute, Kansas City, MO 64111, USA
    Am Heart J 151:589-97. 2006
    ..More information on the longitudinal care and outcomes of patients after myocardial infarction (MI) is needed to further improve the quality of MI care. The PREMIER study was designed to meet this need...
  15. ncbi request reprint The peripheral artery questionnaire: a new disease-specific health status measure for patients with peripheral arterial disease
    John Spertus
    Mid America Heart Institute of Saint Luke s Hospital and the University of Missouri Kansas City, Kansas City, MO, USA
    Am Heart J 147:301-8. 2004
    ..The Peripheral Artery Questionnaire (PAQ) is a 20-item questionnaire developed to meet this need by quantifying patients' physical limitations, symptoms, social function, treatment satisfaction, and quality of life...
  16. ncbi request reprint Monitoring clinical changes in patients with heart failure: a comparison of methods
    John Spertus
    Mid America Heart Institute, Saint Luke s Hospital, Kansas City, MO, USA
    Am Heart J 150:707-15. 2005
    ..This study sought to describe changes in various measures of disease status associated with gradations of clinical change...
  17. ncbi request reprint Effect of difficulty affording health care on health status after coronary revascularization
    John Spertus
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, MO, USA
    Circulation 111:2572-8. 2005
    ..We assessed the effect of difficulty affording health care on the health status (symptoms, function, and quality of life) of patients treated with percutaneous coronary intervention or CABG...
  18. ncbi request reprint The influence of race on health status outcomes one year after an acute coronary syndrome
    John Spertus
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, Missouri 64111, USA
    J Am Coll Cardiol 46:1838-44. 2005
    ..The goal of this study was to compare health status (symptoms, function, and quality of life) outcomes of whites and blacks one year after an acute coronary syndrome (ACS)...
  19. ncbi request reprint Risk of restenosis and health status outcomes for patients undergoing percutaneous coronary intervention versus coronary artery bypass graft surgery
    John A Spertus
    Mid America Heart Institute of Saint Luke s Hospital and the University of Missouri, 4401 Wornall Rd, Kansas City, MO 64111, USA
    Circulation 111:768-73. 2005
    ..No previous studies comparing the health status outcomes of PCI and CABG have examined differences in these outcomes as a function of patients' preprocedural risk for restenosis...
  20. ncbi request reprint Health status predicts long-term outcome in outpatients with coronary disease
    John A Spertus
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, MO 64111, USA
    Circulation 106:43-9. 2002
    ..Demonstrating that they independently predict mortality and hospitalizations among outpatients with coronary disease could emphasize their clinical value...
  21. pmc Validity, reliability, and responsiveness of the Kansas City Cardiomyopathy Questionnaire in anemic heart failure patients
    John A Spertus
    Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, USA
    Qual Life Res 17:291-8. 2008
    ....
  22. ncbi request reprint Integrating baseline health status data collection into the process of care
    J A Spertus
    Section of Cardiology, Department of Medicine, University of Missouri Kansas City, Missouri, USA
    Jt Comm J Qual Improv 27:369-80. 2001
    ..The Mid America Heart Institute of Saint Luke's Hospital (Kansas City, Mo), attempted to integrate the collection of health status assessments within the process of performing coronary revascularization...
  23. doi request reprint Evolving applications for patient-centered health status measures
    John A Spertus
    University of Missouri at Kansas City School of Medicine, Kansas City, MO, USA
    Circulation 118:2103-10. 2008
    ..By becoming aware of the evolving roles of health status measures, clinicians can help to accelerate the realization of the Institute of Medicine's vision for a more transparent, evidence-based, patient-centered healthcare system...
  24. ncbi request reprint Benefits of an "angina clinic" for patients with coronary artery disease: a demonstration of health status measures as markers of health care quality
    John A Spertus
    Department of Medicine, Section of Cardiology, Mid America Heart Institute, University of Missouri, Kansas City, MO 64111, USA
    Am Heart J 143:145-50. 2002
    ..Our purpose was to determine the efficacy of health status measurement in quantifying improvements in quality of care provided by an "angina clinic."..
  25. ncbi request reprint Expanding the outcomes in clinical trials of heart failure: the quality of life and economic components of EPHESUS (EPlerenone's neuroHormonal Efficacy and SUrvival Study)
    John A Spertus
    Mid America Heart Institute and the University of Missouri, Kansas City, MO, USA
    Am Heart J 143:636-42. 2002
    ....
  26. ncbi request reprint Predictors of quality-of-life benefit after percutaneous coronary intervention
    John A Spertus
    University of Missouri Kansas City, and Mid America Heart Institute of Saint Luke s Hospital, USA
    Circulation 110:3789-94. 2004
    ..This study was conducted to identify patient characteristics associated with quality-of-life benefit after PCI...
  27. ncbi request reprint A comparison of the recovery of health status after percutaneous coronary intervention and coronary artery bypass
    A Michael Borkon
    Mid America Heart Institute, Kansas City, Missouri, USA
    Ann Thorac Surg 74:1526-30; discussion 1530. 2002
    ..Selection of the optimum mode of coronary revascularization should not only be directed by technical outcomes, but should also consider patients' postprocedural health status, including symptoms, functionality, and quality of life...
  28. ncbi request reprint Relation of anemia at discharge to survival after acute coronary syndromes
    Joseph Vaglio
    Mid America Heart Institute of Saint Luke s Hospital, Missouri, USA
    Am J Cardiol 96:496-9. 2005
    ..5%, p < 0.001). In multivariable analyses, adjusted hazard ratios for all-cause mortality were 1.57 (95% confidence interval 0.82 to 2.96) for mild anemia and 2.46 (95% confidence interval 1.25 to 4.85) for moderate/severe anemia...
  29. ncbi request reprint Prognostic value of health status in patients with heart failure after acute myocardial infarction
    Gabriel E Soto
    Washington University School of Medicine, St Louis, MO, USA
    Circulation 110:546-51. 2004
    ..Understanding the relationship between KCCQ scores and prognosis may assist clinicians in both interpreting KCCQ scores and stratifying risk in patients...
  30. ncbi request reprint Association between depression and worse disease-specific functional status in outpatients with coronary artery disease
    J A Spertus
    Mid America Heart Institute and Section of Cardiology, Department of Medicine, University of Missouri Kansas City, USA
    Am Heart J 140:105-10. 2000
    ..The study was designed as a cross-sectional survey and 3-month longitudinal cohort...
  31. ncbi request reprint Review of available instruments and methods for assessing quality of life in anti-anginal trials
    B D Bliven
    University of Missouri, Kansas City, USA
    Drugs Aging 13:311-20. 1998
    ..In conclusion, a framework is provided for selecting the appropriate instruments and methodology in the context of the clinical trial...
  32. ncbi request reprint Transmyocardial CO(2) laser revascularization improves symptoms, function, and quality of life: 12-month results from a randomized controlled trial
    J A Spertus
    Section of Cardiology, Mid America Heart Institute/University of Missouri--Kansas City 64111, USA
    Am J Med 111:341-8. 2001
    ..CONCLUSIONS: Transmyocardial revascularization may offer a valuable palliative alternative to patients with severe limitations in health status for whom no standard revascularization options exist...
  33. ncbi request reprint Relative benefit of coronary artery bypass grafting versus stent-assisted percutaneous coronary intervention for angina pectoris and multivessel coronary disease in women versus men (one-year results from the Stent or Surgery trial)
    Zefeng Zhang
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    Am J Cardiol 93:404-9. 2004
    ..049 for the interaction among treatment, gender, and follow-up for the quality of life domain). Although CABG may be superior to PCI in men, in women, at 1 year after intervention, both procedures appear equally effective...
  34. doi request reprint Comparison of outcomes among moderate alcohol drinkers before acute myocardial infarction to effect of continued versus discontinuing alcohol intake after the infarct
    Maia D Carter
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, Missouri, USA
    Am J Cardiol 105:1651-4. 2010
    ..In conclusion, these data suggest that there are no adverse effects for moderate drinkers to continue consuming alcohol and that they may have better physical functioning compared to those who quit drinking after an AMI...
  35. ncbi request reprint Low-to-moderate alcohol intake and health status in heart failure patients
    Adam C Salisbury
    University of Missouri Kansas City, Missouri, USA
    J Card Fail 11:323-8. 2005
    ....
  36. ncbi request reprint Does health status differ between men and women in early recovery after myocardial infarction?
    Linda S Garavalia
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, Missouri, University of Missouri Kansas City, Kansas City, Missouri
    J Womens Health (Larchmt) 16:93-101. 2007
    ....
  37. ncbi request reprint Identifying heart failure patients at high risk for near-term cardiovascular events with serial health status assessments
    Mikhail Kosiborod
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, MO 64111, USA
    Circulation 115:1975-81. 2007
    ..We tested whether serial health status assessments with the Kansas City Cardiomyopathy Questionnaire (KCCQ) can identify patients at increased risk for mortality and hospitalization...
  38. ncbi request reprint Time course of depression and outcome of myocardial infarction
    Susmita Parashar
    Divisions of General Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Arch Intern Med 166:2035-43. 2006
    ..Our objective was to evaluate the prognostic importance of transient, new, or persistent depression on outcomes at 6 months after MI...
  39. doi request reprint The relationship between anemia, change in hematocrit over time and change in health status in patients with heart failure after myocardial infarction
    Mikhail Kosiborod
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, Missouri, USA
    J Card Fail 14:27-34. 2008
    ..However, whether changes in hematocrit are associated with changes in health status is unknown...
  40. ncbi request reprint Electronic collection of health-related quality of life data: validity, time benefits, and patient preference
    B D Bliven
    Department of Medicine, Section of Cardiology, University of Missouri, Kansas City, USA
    Qual Life Res 10:15-22. 2001
    ..Data collected in this manner are valid and of comparable quality to self-reported, HRQOL data obtained via paper survey...
  41. doi request reprint Elevated admission glucose and mortality in elderly patients hospitalized with heart failure
    Mikhail Kosiborod
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, MO 64111, USA
    Circulation 119:1899-907. 2009
    ....
  42. doi request reprint Patient health status and costs in heart failure: insights from the eplerenone post-acute myocardial infarction heart failure efficacy and survival study (EPHESUS)
    Paul S Chan
    St Luke s Mid America Heart Institute, Kansas City, MO 64111, USA
    Circulation 119:398-407. 2009
    ..We assessed whether health status assessment with the Kansas City Cardiomyopathy Questionnaire (KCCQ) predicts future costs in stable heart failure outpatients with left ventricular dysfunction after myocardial infarction...
  43. ncbi request reprint Self-reported use of complementary and alternative medicine in patients with previous acute coronary syndrome
    Carole Decker
    Mid America Heart Institute of Saint Lukes Hospital, and School of Nursing, University of Missouri Kansas City, Kansas City, Missouri, USA
    Am J Cardiol 99:930-3. 2007
    ..05, 95% CI 0.87 to 1.28 for using statins). In conclusion, although CAM users with established CAD have worse socioeconomic status than nonusers, we found no evidence that they were less compliant with evidence-based therapies...
  44. ncbi request reprint Confirmation of a heart failure epidemic: findings from the Resource Utilization Among Congestive Heart Failure (REACH) study
    Peter A McCullough
    Department Internal Medicine, Cardiology Section, University of Missouri Kansas City School of Medicine, Truman Medical Center, Kansas City, Missouri 64108, USA
    J Am Coll Cardiol 39:60-9. 2002
    ..The purpose of this study was to create an automated surveillance tool for reporting the incidence, prevalence and processes of care for patients with heart failure...
  45. ncbi request reprint Comparison of quality of life after repeat versus initial coronary artery bypass grafting
    David M Safley
    Mid America Heart Institute of Saint Luke s Hospital, 4401 Wornall Road, Kansas City, MO 64111, USA
    Am J Cardiol 94:494-7. 2004
    ..30], Quality of Life score [SAQ-QoL: 34 +/- 24 vs 35 +/- 5; p = 0.87], and Angina Frequency score (SAQ-AF: 35 +/- 40 vs 25 +/- 24; p = 0.03])...
  46. doi request reprint Glucometrics in patients hospitalized with acute myocardial infarction: defining the optimal outcomes-based measure of risk
    Mikhail Kosiborod
    Mid America Heart Institute of Saint Luke s Hospital, 4401 Wornall Rd, Kansas City, MO 64111, USA
    Circulation 117:1018-27. 2008
    ..Whether metrics that incorporate multiple glucose assessments during acute myocardial infarction hospitalization are better predictors of mortality than admission glucose alone is not well defined...
  47. ncbi request reprint Assessment of and physician response to glycemic control in diabetic patients presenting with an acute coronary syndrome
    Darcy L Green Conaway
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, MO 64111, USA
    Am Heart J 152:1022-7. 2006
    ..The frequency with which physicians assess diabetic patients' glycemic control during an ACS hospitalization is not known and may represent an opportunity for quality improvement...
  48. ncbi request reprint Prevalence and predictors of angina pectoris one month after myocardial infarction
    John A Spertus
    Mid America Heart Institute and University of Missouri Kansas City, Kansas City, Missouri, USA
    Am J Cardiol 98:282-8. 2006
    ..86, 95% CI 1.45 to 2.41), weekly (OR 4.24, 95% CI 3.09 to 5.82), and daily (OR 6.12, 95% CI 3.62 to 10.3) were more likely to have AP 1 month later. In conclusion, > 1 in 4 patients reported AP 1 month after an MI...
  49. ncbi request reprint Age, functional capacity, and health-related quality of life in patients with heart failure
    Frederick A Masoudi
    Department of Medicine, Denver Health Medical Center, Colorado 80204, USA
    J Card Fail 10:368-73. 2004
    ..We compared the relationship between functional limitation and HRQL between older and younger patients with heart failure...
  50. pmc Racial differences in survival after in-hospital cardiac arrest
    Paul S Chan
    Saint Luke s Mid America Heart Institute, Fifth Floor, 4401 Wornall Rd, Kansas City, MO 64111, USA
    JAMA 302:1195-201. 2009
    ..Racial differences in survival have not been previously studied after in-hospital cardiac arrest, an event for which access to care is not likely to influence treatment...
  51. ncbi request reprint Testing the effectiveness of converting patients to long-acting antianginal medications: The Quality of Life in Angina Research Trial (QUART)
    J A Spertus
    Department of Cardiology, University of Missouri Kansas City School of Medicine, Kansas City, MO 64111, USA
    Am Heart J 141:550-8. 2001
    ..Our purpose was to test the hypothesis that converting patients with stable angina to long-acting antianginal medications would improve their functional status, symptom control, treatment satisfaction, and quality of life...
  52. doi request reprint Prevalence and predictors of persistent health status impairment in patients referred to a vascular clinic with intermittent claudication
    D M Safley
    Saint Luke s Mid America Heart Institute, Kansas City, MO, United States
    Eur J Vasc Endovasc Surg 42:355-62. 2011
    ..The goal of treatment for lower extremity peripheral artery disease is often to improve health status. Factors associated with failure to improve are unknown...
  53. ncbi request reprint Depressive symptoms after acute myocardial infarction: evidence for highest rates in younger women
    Susmita Mallik
    Department of Medicine, Division of General Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Arch Intern Med 166:876-83. 2006
    ..In the community, younger women are uniquely prone to depression. Whether younger women are also more likely to have depression during hospitalization with AMI is unknown...
  54. ncbi request reprint Variability in the clinical status of patients with advanced heart failure
    Paul J Hauptman
    Department of Medicine, Saint Louis University School of Medicine, Missouri, USA
    J Card Fail 10:397-402. 2004
    ..The frequency of such follow-up is not established and is likely to depend on the natural history and variability of patients' health status and the availability and use of appropriate treatments...
  55. ncbi request reprint Depression predicts mortality and hospitalization in patients with myocardial infarction complicated by heart failure
    John S Rumsfeld
    Section of Cardiology, Denver VA Medical Center, Denver, Colorado 80220, USA
    Am Heart J 150:961-7. 2005
    ..To evaluate whether depressive symptoms are independently predictive of mortality and hospitalization among patients with acute myocardial infarction (AMI) complicated by heart failure...
  56. pmc Importance of measuring glycosylated hemoglobin in patients with myocardial infarction and known diabetes mellitus
    Joshua M Stolker
    St Luke s Mid America Heart Institute, Kansas City, Missouri, USA
    Am J Cardiol 105:1090-4. 2010
    ..Because much of this variability occurs at the hospital level, the evaluation of DM control could represent an additional quality indicator and an opportunity to advance patient-centered AMI care...
  57. doi request reprint The impact of dyspnea on health-related quality of life in patients with coronary artery disease: results from the PREMIER registry
    Suzanne V Arnold
    Saint Luke s Mid America Heart Institute, Kansas City, MO, USA
    Am Heart J 157:1042-9.e1. 2009
    ..Both angina and dyspnea are prevalent symptoms among post-myocardial infarction (MI) patients. Given their frequent overlap, little is known about the degree to which these symptoms provide independent information in this population...
  58. doi request reprint Drug-eluting stents and the use of percutaneous coronary intervention among patients with class I indications for coronary artery bypass surgery undergoing index revascularization: analysis from the NCDR (National Cardiovascular Data Registry)
    Andrew D Frutkin
    Mid America Heart Institute, University of Missouri Kansas City, Kansas City, MO 64111, USA
    JACC Cardiovasc Interv 2:614-21. 2009
    ..Our purpose was to evaluate percutaneous coronary intervention (PCI) attempt rates in patients with class I indications for coronary artery bypass graft (CABG) surgery after the introduction of drug-eluting stents (DES)...
  59. doi request reprint Relationship between spontaneous and iatrogenic hypoglycemia and mortality in patients hospitalized with acute myocardial infarction
    Mikhail Kosiborod
    Mid America Heart Institute of Saint Luke s Hospital, 4401 Wornall Rd, Kansas City, MO 64111, USA
    JAMA 301:1556-64. 2009
    ..Yet, whether episodic hypoglycemia that occurs as a result of glucose-lowering therapy is harmful in patients with AMI is unknown...
  60. ncbi request reprint Usefulness of myocardial contrast echocardiography in predicting late mortality in patients with anterior wall acute myocardial infarction
    Taiyeb M Khumri
    The Mid America Heart Institute, Kansas City, Missouri, USA
    Am J Cardiol 98:1150-5. 2006
    ..Patients at very high and very low risk of mortality can be identified, and myocardial contrast echocardiographic data are incrementally useful compared with existing clinical and angiographic variables...
  61. ncbi request reprint Genotypes associated with myocardial infarction risk are more common in African Americans than in European Americans
    David E Lanfear
    Washington University School of Medicine, Department of Medicine, St Louis, Missouri 63110 1093, USA
    J Am Coll Cardiol 44:165-7. 2004
    ..This study was designed to describe the frequencies of multiple myocardial infarction (MI) risk-associated genotypes among different racial groups...
  62. doi request reprint Fragmented QRS and mortality risk in patients with left ventricular dysfunction
    Aamir Cheema
    Mid America Heart Institute and the University of Missouri, Kansas City, MO, USA
    Circ Arrhythm Electrophysiol 3:339-44. 2010
    ..Whether fQRS improves patient selection for primary prevention patients eligible for implantable cardioverter-defibrillator (ICD) therapy remains unknown...
  63. ncbi request reprint The elderly: health status benefits and recovery of function one year after coronary artery bypass surgery
    Darcy Green Conaway
    Mid America Heart Institute of Saint Luke s Hospital and the University of Missouri Kansas City, Kansas City, Missouri, USA
    J Am Coll Cardiol 42:1421-6. 2003
    ..The purpose of this study was to describe the health status (symptoms, function, and quality of life) changes of elderly patients undergoing coronary artery bypass grafting (CABG) and compare these to younger patients...
  64. pmc Interaction between PPARA genotype and beta-blocker treatment influences clinical outcomes following acute coronary syndromes
    Sharon Cresci
    Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8086, Saint Louis, MO 63110 1093, USA
    Pharmacogenomics 9:1403-17. 2008
    ....
  65. pmc Automated external defibrillators and survival after in-hospital cardiac arrest
    Paul S Chan
    Saint Luke s Mid America Heart Institute, 4401 Wornall Rd, Fifth Floor, Kansas City, MO 64111, USA
    JAMA 304:2129-36. 2010
    ..Automated external defibrillators (AEDs) improve survival from out-of-hospital cardiac arrests, but data on their effectiveness in hospitalized patients are limited...
  66. doi request reprint Impact of age and medical comorbidity on the effectiveness of implantable cardioverter-defibrillators for primary prevention
    Paul S Chan
    Mid America Heart Institute and University of Missouri, Kansas City, MO 64111, USA
    Circ Cardiovasc Qual Outcomes 2:16-24. 2009
    ....
  67. doi request reprint Association of early follow-up after acute myocardial infarction with higher rates of medication use
    Stacie L Daugherty
    Department of Medicine, Division of Cardiology, University of Colorado Denver Health Sciences Center, Denver, CO, USA
    Arch Intern Med 168:485-91; discussion 492. 2008
    ..Early outpatient follow-up after acute myocardial infarction (AMI) is recommended in guidelines, but its relationship with the use of evidence-based therapies is unknown...
  68. doi request reprint Glucose normalization and outcomes in patients with acute myocardial infarction
    Mikhail Kosiborod
    Department of Cardiovascular Research, Mid America Heart Institute of Saint Luke s Hospital, 4401 Wornall Rd, Kansas City, MO 64111, USA
    Arch Intern Med 169:438-46. 2009
    ..In addition, whether outcomes differ in patients who have spontaneous resolution of hyperglycemia vs those who achieve normoglycemia after treatment with insulin is also unknown...
  69. pmc Exploring patients' reasons for discontinuance of heart medications
    Linda Garavalia
    Department of Psychology, University of Missouri Kansas City, Kansas City, MO, USA
    J Cardiovasc Nurs 24:371-9. 2009
    ..Although rates and consequences of discontinuance vary for different medications, the existing literature provides little insight into reasons for discontinuance...
  70. doi request reprint Predictors of smoking cessation after a myocardial infarction: the role of institutional smoking cessation programs in improving success
    Nazeera Dawood
    Department of Medicine, Emory University School of Medicine, Atlanta, GA 30307, USA
    Arch Intern Med 168:1961-7. 2008
    ..Smoking cessation after myocardial infarction (MI) is an important goal for secondary prevention of mortality. Whether new initiatives to promote cessation improve patients' quit rates after MI is unknown...
  71. doi request reprint Quantifying the early health status benefits of successful chronic total occlusion recanalization: Results from the FlowCardia's Approach to Chronic Total Occlusion Recanalization (FACTOR) Trial
    J Aaron Grantham
    Mid America Heart Institute of Saint Luke s Hospital and the University of Missouri Kansas City, USA
    Circ Cardiovasc Qual Outcomes 3:284-90. 2010
    ..Data on the health status benefits of percutaneous coronary intervention for coronary chronic total occlusions (CTOs), a principal indication for the procedure, are lacking...
  72. doi request reprint Risk factor management after myocardial infarction: reported adherence and outcomes
    Carole Decker
    Mid America Heart Institute at Saint Luke s Hospital in Kansas City, MO 64111, USA
    Am Heart J 157:556-62. 2009
    ..It is not well known how often cardiac patients comply with the list of instructions or what their association is with health status outcomes after an acute myocardial infarction...
  73. doi request reprint Echocardiographic dyssynchrony and health status outcomes from cardiac resynchronization therapy: insights from the PROSPECT trial
    Paul S Chan
    Mid America Heart Institute, Kansas City, Missouri 64111, USA
    JACC Cardiovasc Imaging 3:451-60. 2010
    ..This study sought to assess the prognostic utility of echocardiographic dyssynchrony for health status improvement after cardiac resynchronization therapy (CRT)...
  74. ncbi request reprint Predictors of weight change in overweight patients with myocardial infarction
    Yazid Y Fadl
    Washington University in St Louis, St Louis, MO, USA
    Am Heart J 154:711-7. 2007
    ..Weight loss is recommended among overweight survivors of myocardial infarction (MI). This study describes patterns of weight change among overweight patients with MI and identifies factors associated with weight change...
  75. doi request reprint Bleeding in patients undergoing percutaneous coronary intervention: the development of a clinical risk algorithm from the National Cardiovascular Data Registry
    Sameer K Mehta
    Division of Cardiovascular Research, Mid America Heart Institute, Saint Luke s Hospital, Kansas City, MO 64111, USA
    Circ Cardiovasc Interv 2:222-9. 2009
    ..We identified baseline clinical characteristics associated with bleeding complications after PCI and developed a simplified, clinically useful algorithm to predict patient risk...
  76. ncbi request reprint Quantifying improvement in symptoms, functioning, and quality of life after peripheral endovascular revascularization
    David M Safley
    Mid America Heart Institute, St Luke s Hospital, Kansas City, MO 64111, USA
    Circulation 115:569-75. 2007
    ..Patients with peripheral arterial disease often undergo peripheral endovascular revascularization (PER) to alleviate symptoms. Despite the growth of PER, little information exists quantifying the health status benefits after the procedure...
  77. ncbi request reprint Financial barriers to health care and outcomes after acute myocardial infarction
    Ali R Rahimi
    Department of Medicine, Yale University School of Medicine, New Haven, Conn 06520 8088, USA
    JAMA 297:1063-72. 2007
    ..The prevalence and consequences of financial barriers to health care services and medications are not well documented for patients with an acute myocardial infarction (AMI)...
  78. ncbi request reprint Suspected acute coronary syndrome patients with diabetes and normal troponin-I levels are at risk for early and late death: Identification of a new high-risk acute coronary syndrome population
    Steven P Marso
    Mid America Heart Institute, University of Missouri Kansas City, 64111, USA
    Diabetes Care 29:1931-2. 2006
  79. ncbi request reprint Socioeconomic disparities in outcomes after acute myocardial infarction
    Susannah M Bernheim
    Department of Medicine, Section of Geriatrics, Yale University School of Medicine, New Haven, CT 06520 8088, USA
    Am Heart J 153:313-9. 2007
    ..Patients of low socioeconomic status (SES) have higher mortality after acute myocardial infarction (AMI). Little is known about the underlying mechanisms or the relationship between SES and rehospitalization after AMI...
  80. ncbi request reprint Frequency of compound genotypes associated with beta-blocker efficacy in congestive heart failure
    David E Lanfear
    Washington University School of Medicine, Department of Medicine, 660 S Euclid Ave, Campus Box 8069, St Louis, MO 63110 1093, USA
    Pharmacogenomics 5:553-8. 2004
    ..This study provides the first look into the population frequency of these compound genotypes, and it provides the necessary first step for future evaluation of polygenic strategies to individualize therapy for heart failure...
  81. ncbi request reprint Opportunities for improvement in the diagnosis and treatment of heart failure
    Peter A McCullough
    Department of Basic Science, Cardiology Section, University of Missouri Kansas City School of Medicine, Truman Medical Center, Kansas City, Missouri, USA
    Clin Cardiol 26:231-7. 2003
    ..Improved treatment of congestive heart failure (CHF) can slow disease progression, promote clinical stability, and prolong survival...
  82. ncbi request reprint The prevalence of unrecognized depression in patients with acute coronary syndrome
    Alpesh A Amin
    Mid America Heart Institute of Saint Luke s Hospital, Kansas City, MO, USA
    Am Heart J 152:928-34. 2006
    ..Despite great attention to its prevalence and prognostic import, little is known about how often hospitalized patients with ACS who have significant depressive symptoms are recognized while receiving routine cardiovascular care...
  83. ncbi request reprint Impact of obesity on disease-specific health status after percutaneous coronary intervention in coronary disease patients
    W S Carlos Poston
    Mid America Heart Institute and University of Missouri Kansas City, MO 64110, USA
    Int J Obes Relat Metab Disord 28:1011-7. 2004
    ..This study examined whether obesity is a risk factor for poor quality of life or diminished health status 12-months postprocedure among a large cohort of PCI patients...
  84. pmc Association of decreased glomerular filtration rate with racial differences in survival after acute myocardial infarction
    James B Wetmore
    Division of Nephrology, Department of Medicine, University of Kansas School of Medicine, Kansas City, Kansas, USA
    Clin J Am Soc Nephrol 6:733-40. 2011
    ..However, whether there are racial differences in the prevalence or prognostic importance of renal insufficiency in AMI is unknown...
  85. ncbi request reprint Clinically important differences in health status for patients with heart disease: an expert consensus panel report
    Kathleen W Wyrwich
    Department of Research Methodology, Saint Louis University, St Louis, MO 63103, USA
    Am Heart J 147:615-22. 2004
    ..No important difference standards for the SF-36 have been published for patients with heart disease. This development of CIDs would facilitate the use of health status measures in daily clinical decision-making...
  86. ncbi request reprint Depression and health status in elderly patients with heart failure: a 6-month prospective study in primary care
    Mark D Sullivan
    Department of Psychiatry and Behavioral Studies, University of Washington, Seattle, WA 98195, USA
    Am J Geriatr Cardiol 13:252-60. 2004
    ..This may help explain why depression has been associated with increased health care utilization and costs in this population...
  87. ncbi request reprint Acute noncardiac conditions and in-hospital mortality in patients with acute myocardial infarction
    Judith H Lichtman
    Section of Chronic Disease Epidemiology, Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conn, USA
    Circulation 116:1925-30. 2007
    ..We sought to evaluate the prevalence of acute, severe, noncardiac conditions present at the time of hospital admission with acute myocardial infarction and to assess the association of these conditions with in-hospital mortality...
  88. ncbi request reprint Health status and social risk correlates of extended length of stay following coronary artery bypass surgery
    Gilbert Johnston
    St Joseph Medical Center, Tacoma, Washington, USA
    Ann Thorac Surg 77:557-62. 2004
    ..Our hypothesis was that poorer self-reported health and greater social risk, as measured by standardized instruments, are significantly associated with extended SLOS defined as greater than or equal to 7 days...
  89. ncbi request reprint Anginal symptoms consistently predict total mortality among outpatients with coronary artery disease
    Dariush Mozaffarian
    Health Services Research and Development Center of Excellence, Veterans Affairs Puget Sound Health Care System, University of Washington, Seattle, Wash, USA
    Am Heart J 146:1015-22. 2003
    ....
  90. ncbi request reprint Depressive symptoms are the strongest predictors of short-term declines in health status in patients with heart failure
    John S Rumsfeld
    Cardiology 111B, Denver VA Medical Center, Denver, Colorado 80220, USA
    J Am Coll Cardiol 42:1811-7. 2003
    ..The purpose of this study was to assess whether depressive symptoms are independently associated with changes in heart failure (HF)-specific health status...
  91. ncbi request reprint Impact of angina burden and other factors on treatment satisfaction after acute coronary syndromes
    Sean C Beinart
    Cardiovascular Outcomes Research Center, VA Puget Sound Health Care System, Seattle, Wash, USA
    Am Heart J 146:646-52. 2003
    ..The objective of this study was to identify potentially modifiable factors associated with treatment satisfaction 7 months after ACS...
  92. ncbi request reprint Disease-specific health status after stent-assisted percutaneous coronary intervention and coronary artery bypass surgery: one-year results from the Stent or Surgery trial
    Zefeng Zhang
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Circulation 108:1694-700. 2003
    ..Few data are available regarding the comparative improvement in disease-specific health status after CABG versus percutaneous coronary intervention (PCI) in the era of coronary stenting...
  93. ncbi request reprint History of depression, angina, and quality of life after acute coronary syndromes
    John S Rumsfeld
    Cardiology, Denver VA Medical Center, Denver, Colo 80206, USA
    Am Heart J 145:493-9. 2003
    ..We evaluated the association between a history of depression and patient-reported angina frequency, physical limitation, and quality of life 7 months after discharge from the hospital for ACS...
  94. ncbi request reprint The impact of acute coronary syndrome on clinical, economic, and cardiac-specific health status after coronary artery bypass surgery versus stent-assisted percutaneous coronary intervention: 1-year results from the stent or surgery (SoS) trial
    Zefeng Zhang
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30306, USA
    Am Heart J 150:175-81. 2005
    ..Data are limited regarding the impact of acute coronary syndromes (ACSs) on the relative benefits of coronary artery bypass grafting (CABG) versus stent-assisted percutaneous coronary intervention (PCI)...
  95. pmc Assessing response bias from missing quality of life data: the Heckman method
    Anne E Sales
    HSR and D Center of Excellence, VA Puget Sound Health Care System, University of Washington, Seattle, WA, USA
    Health Qual Life Outcomes 2:49. 2004
    ..The objective of this study was to demonstrate the use of the Heckman two-step method to assess and correct for bias due to missing health related quality of life (HRQL) surveys in a clinical study of acute coronary syndrome (ACS) patients...
  96. ncbi request reprint Predictors of the onset of depressive symptoms in patients with heart failure
    Edward P Havranek
    University of Colorado Health Sciences Center and Denver Health Medical Center, 777 Bannock Street, Denver, CO 80204 4507, USA
    J Am Coll Cardiol 44:2333-8. 2004
    ..The objective of this study was to identify the factors associated with the development of depressive symptoms in outpatients with heart failure (HF)...
  97. ncbi request reprint Summary health status measures in advanced heart failure: relationship to clinical variables and outcome
    Mark D Sullivan
    Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA
    J Card Fail 13:560-8. 2007
    ..Patient-centered health status measures are important because they capture the patient's perspective on their heart failure, but it is unclear which of these have independent prognostic significance...
  98. ncbi request reprint Connexin37 (GJA4) genotype predicts survival after an acute coronary syndrome
    David E Lanfear
    Henry Ford Heart and Vascular Institute and Wayne State University, Detroit, MI, USA
    Am Heart J 154:561-6. 2007
    ..We tested the hypothesis that these genotypes would predict long-term mortality after an acute coronary syndrome (ACS)...
  99. ncbi request reprint Impact of the Food and Drug Administration's Public Health Notification on the adoption of drug-eluting stents
    Jeptha P Curtis
    Yale University, New Haven, Connecticut, USA
    Am J Cardiol 99:1227-9. 2007
    ..By January 2004, DES use had returned to the prenotification rate and continued to increase thereafter. In conclusion, the Food and Drug Administration's notification had a modest but temporary effect on clinical practice...
  100. ncbi request reprint Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
    Thomas M Morgan
    Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Conn 06510, USA
    JAMA 297:1551-61. 2007
    ..Given the numerous, yet inconsistent, reports of genetic variants being associated with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS susceptibility genotypes...
  101. ncbi request reprint Optimal medical therapy with or without PCI for stable coronary disease
    William E Boden
    Western New York Veterans Affairs Healthcare Network and Buffalo General Hospital SUNY, Buffalo, NY 14203, USA
    N Engl J Med 356:1503-16. 2007
    ....

Research Grants10

  1. Transforming PCI Informed Consent into an Evidence-based Decision-making Tool
    John A Spertus; Fiscal Year: 2010
    ..We will then estimate the cost-savings associated with more rational BAT use to test the hypothesis that PRISM will improve the cost-effectiveness of PCI. ..
  2. Transforming PCI Informed Consent into an Evidence-based Decision-making Tool
    John Spertus; Fiscal Year: 2009
    ..We will then estimate the cost-savings associated with more rational BAT use to test the hypothesis that PRISM will improve the cost-effectiveness of PCI. ..
  3. RISK-ADJUSTMENT OF 1-YEAR HEALTH STATUS OUTCOMES IN CAD
    John Spertus; Fiscal Year: 2003
    ....