F A Spencer

Summary

Affiliation: University of Massachusetts Medical Center
Country: USA

Publications

  1. ncbi request reprint Seasonal distribution of acute myocardial infarction in the second National Registry of Myocardial Infarction
    F A Spencer
    Cardiovascular Thrombosis Research Center, Department of Medicine, University of Massachusetts Medical Center, Worcester 01655, USA
    J Am Coll Cardiol 31:1226-33. 1998
  2. ncbi request reprint Enoxaparin, a low molecular weight heparin, inhibits platelet-dependent prothrombinase assembly and activity by factor-Xa neutralization
    F A Spencer
    Cardiovascular Thrombosis Research Center, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01685, USA
    J Thromb Thrombolysis 9:223-8. 2000
  3. ncbi request reprint Fatal cardiac rupture among patients treated with thrombolytic agents and adjunctive thrombin antagonists: observations from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction 9 Study
    R C Becker
    Cardiovascular Thrombosis Research Center, University of Massachusetts Medical School, Worcester 01655 0214, USA
    J Am Coll Cardiol 33:479-87. 1999
  4. ncbi request reprint Early assessment and in-hospital management of patients with acute myocardial infarction at increased risk for adverse outcomes: a nationwide perspective of current clinical practice. The National Registry of Myocardial Infarction (NRMI-2) Participants
    R C Becker
    Cardiovascular Thrombosis Research Center, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Am Heart J 135:786-96. 1998
  5. ncbi request reprint Early clinical outcomes and routine management of patients with non-ST-segment elevation myocardial infarction: a nationwide perspective
    R C Becker
    Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
    Arch Intern Med 161:601-7. 2001
  6. ncbi request reprint Thrombin generation after the abrupt cessation of intravenous unfractionated heparin among patients with acute coronary syndromes: potential mechanisms for heightened prothrombotic potential
    R C Becker
    Cardiovascular Thrombosis Research Center, Laboratory for Vascular Biology Research, University of Massachusetts Medical School, Worcester 01655, USA
    J Am Coll Cardiol 34:1020-7. 1999
  7. ncbi request reprint Age and the utilization of cardiac catheterization following uncomplicated first acute myocardial infarction treated with thrombolytic therapy (The Second National Registry of Myocardial Infarction [NRMI-2])
    F A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 88:107-11. 2001
  8. ncbi request reprint Temporal trends and associated factors of inpatient cardiac rehabilitation in patients with acute myocardial infarction: a community-wide perspective
    F A Spencer
    Department of Medicine, University of Massachusetts Medical School, Worcester, 01655, USA
    J Cardiopulm Rehabil 21:377-84. 2001
  9. ncbi request reprint Novel inhibitors of factor X for use in cardiovascular diseases
    F A Spencer
    Cardiovascular Thrombosis Research Center, UMass Memorial Medical Center, 55 Lake Avenue North, Worcester, MA 01655, USA
    Curr Cardiol Rep 2:395-404. 2000
  10. ncbi request reprint Low molecular weight heparin and unfractionated heparin in the early pharmacologic management of acute coronary syndromes: a meta-analysis of randomized clinical trials
    M T Le Nguyen
    Cardiovascular Thrombosis Research Center, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Thromb Thrombolysis 12:289-95. 2001

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Seasonal distribution of acute myocardial infarction in the second National Registry of Myocardial Infarction
    F A Spencer
    Cardiovascular Thrombosis Research Center, Department of Medicine, University of Massachusetts Medical Center, Worcester 01655, USA
    J Am Coll Cardiol 31:1226-33. 1998
    ..This observational study sought to determine whether cases of acute myocardial infarction (AMI) reported to the second National Registry of Myocardial Infarction (NRMI-2) varied by season...
  2. ncbi request reprint Enoxaparin, a low molecular weight heparin, inhibits platelet-dependent prothrombinase assembly and activity by factor-Xa neutralization
    F A Spencer
    Cardiovascular Thrombosis Research Center, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01685, USA
    J Thromb Thrombolysis 9:223-8. 2000
    ....
  3. ncbi request reprint Fatal cardiac rupture among patients treated with thrombolytic agents and adjunctive thrombin antagonists: observations from the Thrombolysis and Thrombin Inhibition in Myocardial Infarction 9 Study
    R C Becker
    Cardiovascular Thrombosis Research Center, University of Massachusetts Medical School, Worcester 01655 0214, USA
    J Am Coll Cardiol 33:479-87. 1999
    ..Unlike major hemorrhagic complications, there is no evidence that the intensity of anticoagulation associated with heparin or hirudin administration influences the occurrence of rupture...
  4. ncbi request reprint Early assessment and in-hospital management of patients with acute myocardial infarction at increased risk for adverse outcomes: a nationwide perspective of current clinical practice. The National Registry of Myocardial Infarction (NRMI-2) Participants
    R C Becker
    Cardiovascular Thrombosis Research Center, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Am Heart J 135:786-96. 1998
    ....
  5. ncbi request reprint Early clinical outcomes and routine management of patients with non-ST-segment elevation myocardial infarction: a nationwide perspective
    R C Becker
    Division of Cardiovascular Medicine, University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
    Arch Intern Med 161:601-7. 2001
    ..Despite its prevalence, the common demographic features, current hospital-based management, and short-term clinical outcome among patients with non-ST-segment elevation MI remain poorly defined...
  6. ncbi request reprint Thrombin generation after the abrupt cessation of intravenous unfractionated heparin among patients with acute coronary syndromes: potential mechanisms for heightened prothrombotic potential
    R C Becker
    Cardiovascular Thrombosis Research Center, Laboratory for Vascular Biology Research, University of Massachusetts Medical School, Worcester 01655, USA
    J Am Coll Cardiol 34:1020-7. 1999
    ..v.) unfractionated heparin among patients with acute coronary syndromes...
  7. ncbi request reprint Age and the utilization of cardiac catheterization following uncomplicated first acute myocardial infarction treated with thrombolytic therapy (The Second National Registry of Myocardial Infarction [NRMI-2])
    F A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Am J Cardiol 88:107-11. 2001
    ..The efficacy and cost effectiveness of this strategy in these patients has not yet been determined in clinical trials...
  8. ncbi request reprint Temporal trends and associated factors of inpatient cardiac rehabilitation in patients with acute myocardial infarction: a community-wide perspective
    F A Spencer
    Department of Medicine, University of Massachusetts Medical School, Worcester, 01655, USA
    J Cardiopulm Rehabil 21:377-84. 2001
    ..Inpatient CR often represents cardiac patients' first exposure to risk factor modification education and acts as a gateway to outpatient programs...
  9. ncbi request reprint Novel inhibitors of factor X for use in cardiovascular diseases
    F A Spencer
    Cardiovascular Thrombosis Research Center, UMass Memorial Medical Center, 55 Lake Avenue North, Worcester, MA 01655, USA
    Curr Cardiol Rep 2:395-404. 2000
    ..Accordingly, a number of synthetic direct and indirect Xa antagonists are under development for the prevention and treatment of thrombotic disorders. The following review summarizes the evolution of factor Xa antagonists...
  10. ncbi request reprint Low molecular weight heparin and unfractionated heparin in the early pharmacologic management of acute coronary syndromes: a meta-analysis of randomized clinical trials
    M T Le Nguyen
    Cardiovascular Thrombosis Research Center, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Thromb Thrombolysis 12:289-95. 2001
    ..The superiority of LMWH preparations characterized by high in vitro factor Xa to thrombin inhibitory capacity is supported by clinic trial data but requires further investigation...
  11. ncbi request reprint Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein IIb/IIIa (alphaIIb/beta3) receptor-directed platelet inhibition
    Y F Li
    Cardiovascular Thrombosis Research Center, Laboratory for Vascular Biology Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am Heart J 142:204-10. 2001
    ....
  12. ncbi request reprint Asymptomatic thrombophilia--a family affair
    F A Spencer
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Thromb Haemost 3:457-8. 2005
  13. doi request reprint D-dimer testing in pregnant patients: towards determining the next 'level' in the diagnosis of deep vein thrombosis
    W S Chan
    Department of Medicine, Women s College Hospital, Toronto, ON, USA
    J Thromb Haemost 8:1004-11. 2010
    ..We hypothesized that the specificity of sensitive D-dimer assays could be improved without compromising sensitivity by using higher D-dimer cut-off values...