Research Topics
| L SpectorSummaryAffiliation: University of Minnesota Country: USA Publications
Research Grants
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Publications
Medically recorded allergies and the risk of childhood acute lymphoblastic leukaemiaL Spector
Department of Pediatrics, University of Minnesota, 420 Delaware Street SE, MMC 715, Minneapolis, MN 55455, USA
Eur J Cancer 40:579-84. 2004..78; 95% CI: 1.00-14.29) and of asthma (OR=3.10; 95% CI: 1.39-6.95). None of the other allergic conditions were associated with ALL. These results are contrary to those of prior studies of childhood ALL and allergy...
Detection of cotinine in newborn dried blood spotsLogan G Spector
Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street, Southeast, MMC 715, Minneapolis, MN 55455, USA
Cancer Epidemiol Biomarkers Prev 16:1902-5. 2007..These results suggest that DBS analysis may identify infants of women who smoke throughout pregnancy...
Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology groupLogan G Spector
Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
Cancer Epidemiol Biomarkers Prev 14:651-5. 2005..We hypothesized that maternal consumption of dietary DNAt2 inhibitors during pregnancy would increase the risk of infant leukemia, particularly AML(MLL+)...
Feasibility of nationwide birth registry control selection in the United StatesLogan G Spector
Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
Am J Epidemiol 166:852-6. 2007..These results suggest that birth registries may be used to select controls for studies of rare childhood diseases on a national scale...
Childhood cancer following neonatal oxygen supplementationLogan G Spector
Department of Pediatrics, University of Minnesota, Minneapolis, MN 54555, USA
J Pediatr 147:27-31. 2005..To evaluate the relationship between neonatal oxygen supplementation (O2) and childhood cancer in the Collaborative Perinatal Project (CPP)...
Birth characteristics, maternal reproductive history, and the risk of infant leukemia: a report from the Children's Oncology GroupLogan G Spector
Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street Southeast, MMC 715, Minneapolis, MN 55455, USA
Cancer Epidemiol Biomarkers Prev 16:128-34. 2007..Other variables of interest were not notably associated with infant leukemia regardless of MLL status. This investigation further supports the contention that molecularly defined subtypes of infant leukemia have separate etiologies...
Reproductive history, infertility treatment, and the risk of acute leukemia in children with down syndrome: a report from the Children's Oncology GroupSusan E Puumala
Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
Cancer 110:2067-74. 2007..There is mixed evidence for associations between reproductive history or infertility and acute leukemia among children without DS...
Childhood cancer among twins and higher order multiplesSusan E Puumala
Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street, SE, MMC 715, Minneapolis, MN 55455, USA
Cancer Epidemiol Biomarkers Prev 18:162-8. 2009..Our analysis suggests that mechanisms other than birth weight and gestational age may influence the lower risk of Wilms' tumor and neuroblastoma in multiple births...
Bias in studies of parental self-reported occupational exposure and childhood cancerJoachim Schüz
Institute for Medical Biostatistics, Epidemiology, and Informatics IMBEI, University of Mainz, Mainz, Germany
Am J Epidemiol 158:710-6. 2003..However, because future case-control studies will at least partially rely on questionnaire data, improvements including probing questions, better interview techniques, and validation studies are indicated...
Parental and infant characteristics and childhood leukemia in MinnesotaKimberly J Johnson
Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
BMC Pediatr 8:7. 2008..Translocations present in neonatal blood spots and the young age peak of diagnosis suggest that early-life factors are involved in childhood leukemia etiology...
Birth characteristics and Wilms tumor in MinnesotaSusan E Puumala
Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
Int J Cancer 122:1368-73. 2008..All other factors examined showed no association with WT. This study contributes to the mounting evidence that children with large size at birth have an increased risk of WT...
Epidemiology of leukemia in children with Down syndromeJulie A Ross
Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA
Pediatr Blood Cancer 44:8-12. 2005....
Perinatal characteristics and risk of neuroblastomaKimberly J Johnson
Department of Pediatrics, Division of Epidemiology, Clinical Research, University of Minnesota, Minneapolis, MN, USA
Int J Cancer 123:1166-72. 2008..0, 95% CI 1.3-7.2) and maternal age <20 years (HR = 2.6, 95% CI 1.1-6.1) increased risks for infant NB only. Our study provides evidence that a few perinatal exposures as recorded in birth records may play a role in NB etiology...
Etiology of childhood cancer: recent reportsJulie A Ross
Department of Pediatrics, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA
Pediatr Blood Cancer 45:239-41. 2005
Cancer risk among children with very low birth weightsLogan G Spector
Division of Epidemiology Clinical Research, Department of Pediatrics and bMasonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
Pediatrics 124:96-104. 2009..Because data on very low birth weight and other childhood cancers are sparse, we examined the risk of malignancy with very low birth weight in a large data set...
Invited commentary: Birth certificates--a best control scenario?Julie A Ross
Division of Epidemiology and Clinical Research, Department of Pediatrics, and Cancer Center, University of Minnesota, Minneapolis, 55455, USA
Am J Epidemiol 159:922-4; discussion 925. 2004
Maternal health conditions during pregnancy and acute leukemia in children with Down syndrome: A Children's Oncology Group studySimona Ognjanovic
Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
Pediatr Blood Cancer 52:602-8. 2009..We examined whether maternal infections and health conditions during pregnancy were associated with acute leukemia in children with DS...
Parental age and risk of childhood cancer: a pooled analysisKimberly J Johnson
Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
Epidemiology 20:475-83. 2009..Few risk factors for childhood cancer are well-established. We investigated whether advancing parental age increases childhood cancer risk...
Family history of cancer and malignant germ cell tumors in children: a report from the Children's Oncology GroupJenny N Poynter
Department of Pediatrics, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Minneapolis, MN 55455, USA
Cancer Causes Control 21:181-9. 2010..46, 95% CI 0.22-0.96). These sex and cancer site specific associations should be confirmed in additional studies as they may provide clues to the etiology of pediatric GCT...
Comparability and representativeness of control groups in a case-control study of infant leukemia: a report from the Children's Oncology GroupSusan E Puumala
Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
Am J Epidemiol 170:379-87. 2009..3,317 g). Finally, participating BC mothers were likely to be older and to have more education than nonparticipants. Thus, the study's control groups were comparable but differed from the population of interest...
Birth characteristics and the risk of childhood rhabdomyosarcoma based on histological subtypeS Ognjanovic
Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
Br J Cancer 102:227-31. 2010..Little is known about risk factors for childhood rhabdomyosarcoma (RMS) and the histology-specific details are rare...
The epidemiology of childhood leukemia with a focus on birth weight and dietRichard L Tower
Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA
Crit Rev Clin Lab Sci 44:203-42. 2007..Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms modify this risk...
Infant leukemia and parental infertility or its treatment: a Children's Oncology Group reportSusan E Puumala
Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
Hum Reprod 25:1561-8. 2010..Parental infertility and infertility treatment have been studied with regard to childhood cancer in general, but rarely in individual cancer subtypes...
Hepatoblastoma and low birth weightLogan G Spector
Pediatr Blood Cancer 43:706. 2004
Secular trends in response rates for controls selected by random digit dialing in childhood cancer studies: a report from the Children's Oncology GroupGreta R Bunin
Division of Oncology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Am J Epidemiol 166:109-16. 2007..4% per year (95% CI: -2.7, -2.0; p < 0.001). The current low response rates for RDD indicate a substantial potential for selection bias and a need to seek alternative sources of controls...
Childhood cancer and birthmarks in the Collaborative Perinatal ProjectKimberly J Johnson
Department of Pediatrics, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA
Pediatrics 119:e1088-93. 2007....
Child and maternal household chemical exposure and the risk of acute leukemia in children with Down's syndrome: a report from the Children's Oncology GroupLucy E Alderton
Division of Epidemiology, University of Minnesota School of Public Health, Minneapolis, 55455, USA
Am J Epidemiol 164:212-21. 2006..0. This exploratory study suggests that household chemical exposure may play a role in the development of acute lymphoblastic leukemia in children with Down's syndrome...
Infant leukemia: finding the needle in the haystackLogan G Spector
Cancer Epidemiol Biomarkers Prev 15:2331. 2006
Early postnatal weight gain, intellectual performance, and body mass index at 7 years of age in term infants with intrauterine growth restrictionMary Pylipow
Division of Neonatology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
J Pediatr 154:201-6. 2009..To determine whether the postnatal growth rate of infants with intrauterine growth restriction (IUGR) is associated with later cognitive function and body mass index (BMI)...
Ontogeny of gene expression: a changing environment for malignancyLogan G Spector
Cancer Epidemiol Biomarkers Prev 17:1021-3. 2008
Leukemia in the mothers of big babies--does the tree fall far from the apple?Logan G Spector
Leuk Res 32:1644-5. 2008
Research Grants
- Genetic Epidemiology of OsteosarcomaLOGAN SPECTOR; Fiscal Year: 2007..Data concerning diet, physical activity, family health history, and anthropometries will also be collected through mailed surveys of parents and children. ..
