L Spector

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Medically recorded allergies and the risk of childhood acute lymphoblastic leukaemia
    L Spector
    Department of Pediatrics, University of Minnesota, 420 Delaware Street SE, MMC 715, Minneapolis, MN 55455, USA
    Eur J Cancer 40:579-84. 2004
  2. ncbi request reprint Detection of cotinine in newborn dried blood spots
    Logan G Spector
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street, Southeast, MMC 715, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 16:1902-5. 2007
  3. ncbi request reprint Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology group
    Logan G Spector
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 14:651-5. 2005
  4. ncbi request reprint Feasibility of nationwide birth registry control selection in the United States
    Logan G Spector
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Am J Epidemiol 166:852-6. 2007
  5. ncbi request reprint Childhood cancer following neonatal oxygen supplementation
    Logan G Spector
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 54555, USA
    J Pediatr 147:27-31. 2005
  6. ncbi request reprint Birth characteristics, maternal reproductive history, and the risk of infant leukemia: a report from the Children's Oncology Group
    Logan G Spector
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street Southeast, MMC 715, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 16:128-34. 2007
  7. ncbi request reprint Reproductive history, infertility treatment, and the risk of acute leukemia in children with down syndrome: a report from the Children's Oncology Group
    Susan E Puumala
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    Cancer 110:2067-74. 2007
  8. pmc Childhood cancer among twins and higher order multiples
    Susan E Puumala
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street, SE, MMC 715, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 18:162-8. 2009
  9. ncbi request reprint Bias in studies of parental self-reported occupational exposure and childhood cancer
    Joachim Schüz
    Institute for Medical Biostatistics, Epidemiology, and Informatics IMBEI, University of Mainz, Mainz, Germany
    Am J Epidemiol 158:710-6. 2003
  10. pmc Parental and infant characteristics and childhood leukemia in Minnesota
    Kimberly J Johnson
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    BMC Pediatr 8:7. 2008

Research Grants

  1. Genetic Epidemiology of Osteosarcoma
    LOGAN SPECTOR; Fiscal Year: 2007

Detail Information

Publications31

  1. ncbi request reprint Medically recorded allergies and the risk of childhood acute lymphoblastic leukaemia
    L Spector
    Department of Pediatrics, University of Minnesota, 420 Delaware Street SE, MMC 715, Minneapolis, MN 55455, USA
    Eur J Cancer 40:579-84. 2004
    ..78; 95% CI: 1.00-14.29) and of asthma (OR=3.10; 95% CI: 1.39-6.95). None of the other allergic conditions were associated with ALL. These results are contrary to those of prior studies of childhood ALL and allergy...
  2. ncbi request reprint Detection of cotinine in newborn dried blood spots
    Logan G Spector
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street, Southeast, MMC 715, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 16:1902-5. 2007
    ..These results suggest that DBS analysis may identify infants of women who smoke throughout pregnancy...
  3. ncbi request reprint Maternal diet and infant leukemia: the DNA topoisomerase II inhibitor hypothesis: a report from the children's oncology group
    Logan G Spector
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 14:651-5. 2005
    ..We hypothesized that maternal consumption of dietary DNAt2 inhibitors during pregnancy would increase the risk of infant leukemia, particularly AML(MLL+)...
  4. ncbi request reprint Feasibility of nationwide birth registry control selection in the United States
    Logan G Spector
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Am J Epidemiol 166:852-6. 2007
    ..These results suggest that birth registries may be used to select controls for studies of rare childhood diseases on a national scale...
  5. ncbi request reprint Childhood cancer following neonatal oxygen supplementation
    Logan G Spector
    Department of Pediatrics, University of Minnesota, Minneapolis, MN 54555, USA
    J Pediatr 147:27-31. 2005
    ..To evaluate the relationship between neonatal oxygen supplementation (O2) and childhood cancer in the Collaborative Perinatal Project (CPP)...
  6. ncbi request reprint Birth characteristics, maternal reproductive history, and the risk of infant leukemia: a report from the Children's Oncology Group
    Logan G Spector
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street Southeast, MMC 715, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 16:128-34. 2007
    ..Other variables of interest were not notably associated with infant leukemia regardless of MLL status. This investigation further supports the contention that molecularly defined subtypes of infant leukemia have separate etiologies...
  7. ncbi request reprint Reproductive history, infertility treatment, and the risk of acute leukemia in children with down syndrome: a report from the Children's Oncology Group
    Susan E Puumala
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    Cancer 110:2067-74. 2007
    ..There is mixed evidence for associations between reproductive history or infertility and acute leukemia among children without DS...
  8. pmc Childhood cancer among twins and higher order multiples
    Susan E Puumala
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, 420 Delaware Street, SE, MMC 715, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 18:162-8. 2009
    ..Our analysis suggests that mechanisms other than birth weight and gestational age may influence the lower risk of Wilms' tumor and neuroblastoma in multiple births...
  9. ncbi request reprint Bias in studies of parental self-reported occupational exposure and childhood cancer
    Joachim Schüz
    Institute for Medical Biostatistics, Epidemiology, and Informatics IMBEI, University of Mainz, Mainz, Germany
    Am J Epidemiol 158:710-6. 2003
    ..However, because future case-control studies will at least partially rely on questionnaire data, improvements including probing questions, better interview techniques, and validation studies are indicated...
  10. pmc Parental and infant characteristics and childhood leukemia in Minnesota
    Kimberly J Johnson
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    BMC Pediatr 8:7. 2008
    ..Translocations present in neonatal blood spots and the young age peak of diagnosis suggest that early-life factors are involved in childhood leukemia etiology...
  11. ncbi request reprint Birth characteristics and Wilms tumor in Minnesota
    Susan E Puumala
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Int J Cancer 122:1368-73. 2008
    ..All other factors examined showed no association with WT. This study contributes to the mounting evidence that children with large size at birth have an increased risk of WT...
  12. ncbi request reprint Epidemiology of leukemia in children with Down syndrome
    Julie A Ross
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Pediatr Blood Cancer 44:8-12. 2005
    ....
  13. doi request reprint Perinatal characteristics and risk of neuroblastoma
    Kimberly J Johnson
    Department of Pediatrics, Division of Epidemiology, Clinical Research, University of Minnesota, Minneapolis, MN, USA
    Int J Cancer 123:1166-72. 2008
    ..0, 95% CI 1.3-7.2) and maternal age <20 years (HR = 2.6, 95% CI 1.1-6.1) increased risks for infant NB only. Our study provides evidence that a few perinatal exposures as recorded in birth records may play a role in NB etiology...
  14. ncbi request reprint Etiology of childhood cancer: recent reports
    Julie A Ross
    Department of Pediatrics, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Pediatr Blood Cancer 45:239-41. 2005
  15. pmc Cancer risk among children with very low birth weights
    Logan G Spector
    Division of Epidemiology Clinical Research, Department of Pediatrics and bMasonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Pediatrics 124:96-104. 2009
    ..Because data on very low birth weight and other childhood cancers are sparse, we examined the risk of malignancy with very low birth weight in a large data set...
  16. ncbi request reprint Invited commentary: Birth certificates--a best control scenario?
    Julie A Ross
    Division of Epidemiology and Clinical Research, Department of Pediatrics, and Cancer Center, University of Minnesota, Minneapolis, 55455, USA
    Am J Epidemiol 159:922-4; discussion 925. 2004
  17. pmc Maternal health conditions during pregnancy and acute leukemia in children with Down syndrome: A Children's Oncology Group study
    Simona Ognjanovic
    Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    Pediatr Blood Cancer 52:602-8. 2009
    ..We examined whether maternal infections and health conditions during pregnancy were associated with acute leukemia in children with DS...
  18. pmc Parental age and risk of childhood cancer: a pooled analysis
    Kimberly J Johnson
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
    Epidemiology 20:475-83. 2009
    ..Few risk factors for childhood cancer are well-established. We investigated whether advancing parental age increases childhood cancer risk...
  19. pmc Family history of cancer and malignant germ cell tumors in children: a report from the Children's Oncology Group
    Jenny N Poynter
    Department of Pediatrics, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Minneapolis, MN 55455, USA
    Cancer Causes Control 21:181-9. 2010
    ..46, 95% CI 0.22-0.96). These sex and cancer site specific associations should be confirmed in additional studies as they may provide clues to the etiology of pediatric GCT...
  20. pmc Comparability and representativeness of control groups in a case-control study of infant leukemia: a report from the Children's Oncology Group
    Susan E Puumala
    Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Am J Epidemiol 170:379-87. 2009
    ..3,317 g). Finally, participating BC mothers were likely to be older and to have more education than nonparticipants. Thus, the study's control groups were comparable but differed from the population of interest...
  21. pmc Birth characteristics and the risk of childhood rhabdomyosarcoma based on histological subtype
    S Ognjanovic
    Division of Pediatric Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Br J Cancer 102:227-31. 2010
    ..Little is known about risk factors for childhood rhabdomyosarcoma (RMS) and the histology-specific details are rare...
  22. ncbi request reprint The epidemiology of childhood leukemia with a focus on birth weight and diet
    Richard L Tower
    Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Crit Rev Clin Lab Sci 44:203-42. 2007
    ..Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms modify this risk...
  23. pmc Infant leukemia and parental infertility or its treatment: a Children's Oncology Group report
    Susan E Puumala
    Division of Epidemiology Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
    Hum Reprod 25:1561-8. 2010
    ..Parental infertility and infertility treatment have been studied with regard to childhood cancer in general, but rarely in individual cancer subtypes...
  24. ncbi request reprint Hepatoblastoma and low birth weight
    Logan G Spector
    Pediatr Blood Cancer 43:706. 2004
  25. ncbi request reprint Secular trends in response rates for controls selected by random digit dialing in childhood cancer studies: a report from the Children's Oncology Group
    Greta R Bunin
    Division of Oncology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Am J Epidemiol 166:109-16. 2007
    ..4% per year (95% CI: -2.7, -2.0; p < 0.001). The current low response rates for RDD indicate a substantial potential for selection bias and a need to seek alternative sources of controls...
  26. ncbi request reprint Childhood cancer and birthmarks in the Collaborative Perinatal Project
    Kimberly J Johnson
    Department of Pediatrics, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA
    Pediatrics 119:e1088-93. 2007
    ....
  27. ncbi request reprint Child and maternal household chemical exposure and the risk of acute leukemia in children with Down's syndrome: a report from the Children's Oncology Group
    Lucy E Alderton
    Division of Epidemiology, University of Minnesota School of Public Health, Minneapolis, 55455, USA
    Am J Epidemiol 164:212-21. 2006
    ..0. This exploratory study suggests that household chemical exposure may play a role in the development of acute lymphoblastic leukemia in children with Down's syndrome...
  28. ncbi request reprint Infant leukemia: finding the needle in the haystack
    Logan G Spector
    Cancer Epidemiol Biomarkers Prev 15:2331. 2006
  29. doi request reprint Early postnatal weight gain, intellectual performance, and body mass index at 7 years of age in term infants with intrauterine growth restriction
    Mary Pylipow
    Division of Neonatology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    J Pediatr 154:201-6. 2009
    ..To determine whether the postnatal growth rate of infants with intrauterine growth restriction (IUGR) is associated with later cognitive function and body mass index (BMI)...
  30. doi request reprint Ontogeny of gene expression: a changing environment for malignancy
    Logan G Spector
    Cancer Epidemiol Biomarkers Prev 17:1021-3. 2008
  31. ncbi request reprint Leukemia in the mothers of big babies--does the tree fall far from the apple?
    Logan G Spector
    Leuk Res 32:1644-5. 2008

Research Grants2

  1. Genetic Epidemiology of Osteosarcoma
    LOGAN SPECTOR; Fiscal Year: 2007
    ..Data concerning diet, physical activity, family health history, and anthropometries will also be collected through mailed surveys of parents and children. ..