Research Topics
| Louis J SparveroSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammationLouis J Sparvero
Departments of Surgery and Bioengineering, University of Pittsburgh Cancer Institute, Pittsburgh, USA
J Transl Med 7:17. 2009..Understanding the molecular structure and function of it and its ligands in the setting of inflammation is critically important in understanding the role of this receptor in tumor biology...
Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injuryJing Ji
Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Nat Neurosci 15:1407-13. 2012..We conclude that cardiolipin oxygenation generates neuronal death signals and that prevention of it by mitochondria-targeted small molecule inhibitors represents a new target for neuro-drug discovery...- Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectationsLouis J Sparvero
Center for Free Radical and Antioxidant Health, Pittsburgh, PA 15213, USA
Chem Phys Lipids 165:545-62. 2012..This is followed by a review of the current literature, including methodologies that other laboratories have used to overcome these challenges... - Adsorption of surfactant lipids by single-walled carbon nanotubes in mouse lung upon pharyngeal aspirationAlexander A Kapralov
Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
ACS Nano 6:4147-56. 2012..Taken together, this is the first demonstration of the in vivo adsorption of the surfactant lipids and proteins on SWCNTs in a physiologically relevant animal model... 
The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunityMichael T Lotze
Department of Surgery, G 27A Hillman Cancer Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
Immunol Rev 220:60-81. 2007....- Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipinAlejandro K Samhan-Arias
Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA, USA Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, PA, USA
Biochim Biophys Acta 1818:2413-23. 2012..This article is part of a Special Issue entitled: Oxidized phospholipids - their properties and interactions with proteins... - Global phospholipidomics analysis reveals selective pulmonary peroxidation profiles upon inhalation of single-walled carbon nanotubesYulia Y Tyurina
Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
ACS Nano 5:7342-53. 2011.... - CD8+ T-cell responses against hemoglobin-beta prevent solid tumor growthHideo Komita
Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Cancer Res 68:8076-84. 2008..Importantly, there were no untoward effects of vaccination with the HBB peptide on peripheral RBC numbers, RBC hemoglobin content, or vascular structures in the brain or eye... - Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injuryLouis J Sparvero
Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Neurochem 115:1322-36. 2010....