Louis J Sparvero

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation
    Louis J Sparvero
    Departments of Surgery and Bioengineering, University of Pittsburgh Cancer Institute, Pittsburgh, USA
    J Transl Med 7:17. 2009
  2. pmc Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury
    Jing Ji
    Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Nat Neurosci 15:1407-13. 2012
  3. pmc Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations
    Louis J Sparvero
    Center for Free Radical and Antioxidant Health, Pittsburgh, PA 15213, USA
    Chem Phys Lipids 165:545-62. 2012
  4. pmc Adsorption of surfactant lipids by single-walled carbon nanotubes in mouse lung upon pharyngeal aspiration
    Alexander A Kapralov
    Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    ACS Nano 6:4147-56. 2012
  5. ncbi request reprint The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity
    Michael T Lotze
    Department of Surgery, G 27A Hillman Cancer Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
    Immunol Rev 220:60-81. 2007
  6. pmc Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin
    Alejandro K Samhan-Arias
    Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA, USA
    Biochim Biophys Acta 1818:2413-23. 2012
  7. pmc Global phospholipidomics analysis reveals selective pulmonary peroxidation profiles upon inhalation of single-walled carbon nanotubes
    Yulia Y Tyurina
    Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    ACS Nano 5:7342-53. 2011
  8. pmc CD8+ T-cell responses against hemoglobin-beta prevent solid tumor growth
    Hideo Komita
    Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Cancer Res 68:8076-84. 2008
  9. pmc Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury
    Louis J Sparvero
    Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Neurochem 115:1322-36. 2010

Collaborators

Detail Information

Publications9

  1. pmc RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation
    Louis J Sparvero
    Departments of Surgery and Bioengineering, University of Pittsburgh Cancer Institute, Pittsburgh, USA
    J Transl Med 7:17. 2009
    ..Understanding the molecular structure and function of it and its ligands in the setting of inflammation is critically important in understanding the role of this receptor in tumor biology...
  2. pmc Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury
    Jing Ji
    Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Nat Neurosci 15:1407-13. 2012
    ..We conclude that cardiolipin oxygenation generates neuronal death signals and that prevention of it by mitochondria-targeted small molecule inhibitors represents a new target for neuro-drug discovery...
  3. pmc Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations
    Louis J Sparvero
    Center for Free Radical and Antioxidant Health, Pittsburgh, PA 15213, USA
    Chem Phys Lipids 165:545-62. 2012
    ..This is followed by a review of the current literature, including methodologies that other laboratories have used to overcome these challenges...
  4. pmc Adsorption of surfactant lipids by single-walled carbon nanotubes in mouse lung upon pharyngeal aspiration
    Alexander A Kapralov
    Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    ACS Nano 6:4147-56. 2012
    ..Taken together, this is the first demonstration of the in vivo adsorption of the surfactant lipids and proteins on SWCNTs in a physiologically relevant animal model...
  5. ncbi request reprint The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity
    Michael T Lotze
    Department of Surgery, G 27A Hillman Cancer Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
    Immunol Rev 220:60-81. 2007
    ....
  6. pmc Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin
    Alejandro K Samhan-Arias
    Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, PA, USA
    Biochim Biophys Acta 1818:2413-23. 2012
    ..This article is part of a Special Issue entitled: Oxidized phospholipids - their properties and interactions with proteins...
  7. pmc Global phospholipidomics analysis reveals selective pulmonary peroxidation profiles upon inhalation of single-walled carbon nanotubes
    Yulia Y Tyurina
    Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    ACS Nano 5:7342-53. 2011
    ....
  8. pmc CD8+ T-cell responses against hemoglobin-beta prevent solid tumor growth
    Hideo Komita
    Department of Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Cancer Res 68:8076-84. 2008
    ..Importantly, there were no untoward effects of vaccination with the HBB peptide on peripheral RBC numbers, RBC hemoglobin content, or vascular structures in the brain or eye...
  9. pmc Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury
    Louis J Sparvero
    Center for Free Radical and Antioxidant Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Neurochem 115:1322-36. 2010
    ....