Research Topics
| C A SorknessSummaryAffiliation: University of Wisconsin Country: USA Publications
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Detail Information
Publications
Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthmaSandra D Anderson
Department of Respiratory and Sleep Medicine, 11 West, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW 2050, Australia
Respir Res 11:120. 2010..This study examined reproducibility of % fall in FEV1 and area under the FEV1 time curve for 30 minutes in response to two exercise tests performed with the same intensity and duration of exercise, and inspired air conditions...
Recruitment strategies in the Asthma Clinical Research NetworkC A Sorkness
University of Wisconsin, Madison, WI 53792 3244, USA
Control Clin Trials 22:222S-35S. 2001..Particular attention is given to the strategies for the recruitment of women and minorities. Finally, the specific strategies of each of the six ACRN clinical centers are presented...- Long-term comparison of 3 controller regimens for mild-moderate persistent childhood asthma: the Pediatric Asthma Controller TrialChristine A Sorkness
Clinical Science Center, University of Wisconsin, Madison, WI 53792, USA
J Allergy Clin Immunol 119:64-72. 2007..More evidence is needed on which to base recommendations for treatment of mild-moderate persistent asthma in school-aged children... - Phenotypic predictors of long-term response to inhaled corticosteroid and leukotriene modifier therapies in pediatric asthmaJason E Knuffman
Schools of Medicine and Pharmacy, University of Wisconsin, Madison, Wis, USA
J Allergy Clin Immunol 123:411-6. 2009..In children with mild-to-moderate persistent asthma, identification of phenotypic predictors to guide selection of a controller regimen is essential... - Randomized trial of omalizumab (anti-IgE) for asthma in inner-city childrenWilliam W Busse
Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53719, USA
N Engl J Med 364:1005-15. 2011..It has also revealed the limitations of environmental remediation and guidelines-based therapy in achieving greater disease control... - Variability in asthma severity in pediatric subjects with asthma previously receiving short-acting beta2-agonistsBradley E Chipps
Capital Allergy and Respiratory Disease Center, Sacramento, California 95819, and University of Wisconsin, Madison, Wisconsin, USA
J Pediatr 148:517-21. 2006..At baseline, all subjects met National Asthma Education and Prevention Program criteria for moderate/severe asthma... - Traditional and new approaches to asthma monitoringChristine A Sorkness
School of Pharmacy, University of Wisconsin, 777 Highland Avenue, Madison, WI 53705, USA
Respir Care 53:593-9; discussion 599-601. 2008..New approaches to asthma monitoring, such as airway hyperresponsiveness, sputum eosinophils, exhaled nitric oxide, and pharmacogenetic measurements, will be critiqued... - Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroidsRobert F Lemanske
University of Wisconsin School of Medicine and Public Health, Madison, USA
N Engl J Med 362:975-85. 2010..For children who have uncontrolled asthma despite the use of low-dose inhaled corticosteroids (ICS), evidence to guide step-up therapy is lacking... - Association of obstructive sleep apnea risk with asthma control in adultsMihaela Teodorescu
Medical Service, William S Middleton Memorial Veterans Hospital, Madison, WI, USA
Chest 138:543-50. 2010..Unrecognized obstructive sleep apnea (OSA) may lead to poor asthma control despite optimal therapy. Our objective was to evaluate the relationship between OSA risk and asthma control in adults... - Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trialR F Lemanske
University of Wisconsin Children s Hospital, 600 Highland Ave, K4 916 9988, Madison, WI 53792, USA
JAMA 285:2594-603. 2001..Inhaled long-acting beta(2)-agonists improve asthma control when added to inhaled corticosteroid (ICS) therapy... - Potential interaction between warfarin and dicloxacillinA T Mailloux
School of Pharmacy, University of Wisconsin, Madison 53706, USA
Ann Pharmacother 30:1402-7. 1996..To report a case and retrospective review of seven patients who experienced a decrease in prothrombin time during concomitant administration of warfarin and dicloxacillin... - The use of inhaled corticosteroids in adult asthmaAnthony G Staresinic
Pharmacy Practice Division, University of Wisconsin School of Pharmacy, 777 Highland Avenue, Madison, WI 53705-2222, USA
Med Clin North Am 86:1035-47. 2002..The use of ICS in patients whose asthma is mild, with essentially normal lung function, and infrequent symptoms also remains unstudied. For the time being, ICS remain the first line of asthma treatment for adults with persistent disease... - Characterization of within-subject responses to fluticasone and montelukast in childhood asthmaStanley J Szefler
Department of Pediatrics, National Jewish Medical and Research Medical Center and University of Colorado Health Sciences Center, Denver, CO 80206, USA
J Allergy Clin Immunol 115:233-42. 2005..Responses to inhaled corticosteroids (ICSs) and leukotriene receptor antagonists (LTRAs) vary among asthmatic patients... - Anti-immunoglobulin E therapy with omalizumab for asthmaLeslie Hendeles
Department of Pharmacy Practice, College of Pharmacy and Pediatric Pulmonary Division, College of Medicine, University of Florida, Gainesville, FL, USA
Ann Pharmacother 41:1397-410. 2007..To evaluate data on anti-immunoglobulin E (anti-IgE) therapy for asthma... - The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trialRichard J Martin
National Jewish Medical and Research Center, Denver, CO 80206, USA
J Allergy Clin Immunol 119:73-80. 2007..Although guidelines recommend anti-inflammatory therapy for persistent asthma, recent studies suggest that 25% to 35% of patients with asthma may not improve lung function with inhaled corticosteroids... - Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthmaStephen C Lazarus
University of California, San Francisco, 505 Parnassus Avenue, M 1083, San Francisco, CA 94143 0111, USA
Am J Respir Crit Care Med 175:783-90. 2007..One-quarter to one-third of individuals with asthma smoke, which may affect response to therapy and contribute to poor asthma control... - Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in childrenRobert C Strunk
Washington University School of Medicine, St Louis, MO, USA
J Allergy Clin Immunol 112:883-92. 2003..It is a noninvasive technique that could be used in decisional management of children with asthma... - Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthmaAaron Deykin
Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Am J Respir Crit Care Med 175:228-34. 2007..The elements of asthma control achieved by LABAs (improved lung function) and leukotriene receptor antagonists (LTRAs; protection against exacerbations) may be complementary as well... - Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trialStanley J Szefler
National Jewish Health, Denver, CO, USA
Lancet 372:1065-72. 2008.... - Significant variability in response to inhaled corticosteroids for persistent asthmaStanley J Szefler
National Jewish Medical and Research Center, Department of Pediatrics, Denver, CO 80206, USA
J Allergy Clin Immunol 109:410-8. 2002..It is possible that higher doses of ICSs are necessary to manage more severe patients or to achieve goals of therapy not evaluated in this study, such as prevention of asthma exacerbations... - Classifying asthma severity in children: mismatch between symptoms, medication use, and lung functionLeonard B Bacharier
Division of Allergy and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, One Children s Place, St Louis, MO 63110, USA
Am J Respir Crit Care Med 170:426-32. 2004..FEV(1) is generally normal, even in severe persistent childhood asthma, whereas FEV(1)/FVC declines as asthma severity increases... - Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trialElliot Israel
Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Lancet 364:1505-12. 2004..However, the existence of any genotype-dependent difference has not been tested in a prospective clinical trial... - Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthmaRobert S Zeiger
Department of Pediatrics, University of California San Diego, San Diego, CA 92111, USA
J Allergy Clin Immunol 117:45-52. 2006..Outcome data are needed to base recommendations for controller asthma medication use in school-aged children... - beta-Adrenergic receptor polymorphisms and response to salmeterolMichael E Wechsler
Brigham and Women s Hospital, 75 Francis Street, Boston, MA, 02115, USA
Am J Respir Crit Care Med 173:519-26. 2006..Several studies suggest that patients with asthma who are homozygous for arginine at the 16th position of the beta2-adrenergic receptor may not benefit from short-acting beta-agonists... - Daily versus as-needed corticosteroids for mild persistent asthmaHomer A Boushey
University of California at San Francisco, San Francisco, USA
N Engl J Med 352:1519-28. 2005..Further studies are required to determine whether this novel approach to treatment should be recommended... - Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroidsAaron Deykin
Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
J Allergy Clin Immunol 115:720-7. 2005..Although inhaled corticosteroids (ICSs) are effective in preventing deterioration in asthma control, at least half of subjects with mild-to-moderate asthma will remain stable when these agents are discontinued... - Systemic effect comparisons of six inhaled corticosteroid preparationsRichard J Martin
National Jewish Medical and Research Center, Denver, Colorado 80206, USA
Am J Respir Crit Care Med 165:1377-83. 2002..This study represents the first step in evaluation of ICS efficacy based on equisystemic (cortisol suppression) effects of a given ICS, rather than doses judged arbitrarily to be comparable on a microgram basis... - Development of the asthma control test: a survey for assessing asthma controlRobert A Nathan
Asthma and allergy Associates and Research Center, Colorado Springs, USA
J Allergy Clin Immunol 113:59-65. 2004..77. CONCLUSION: Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control... - Guideline-defining asthma clinical trials of the National Heart, Lung, and Blood Institute's Asthma Clinical Research Network and Childhood Asthma Research and Education NetworkLoren C Denlinger
Department of Medicine, College of Medicine, Pennsylvania State University, Hershey, PA, USA
J Allergy Clin Immunol 119:3-11; quiz 12-3. 2007.... - IgE-blocking therapy for difficult-to-treat asthma: a brief reviewGailen D Marshall
University of Texas Health Science Center, Houston Medical School, USA
Manag Care 13:45-50. 2004..To review the characteristics of difficult-to-treat asthma and describe patients who may benefit from therapy with the recently approved humanized monoclonal antiimmunoglobulin E (IgE) antibody, omalizumab... - Internet telehealth for pediatric asthma case management: integrating computerized and case manager features for tailoring a Web-based asthma education programMeg Wise
Center for Health Systems Research and Analysis, University of Wisconsin Madison in Madison, Wisconsin, USA
Health Promot Pract 8:282-91. 2007..Implications for health education for chronic disease management are raised... - Long-term inhaled corticosteroids in preschool children at high risk for asthmaTheresa W Guilbert
Division of Pediatric Pulmonary Medicine, Arizona Respiratory Center, University of Arizona, Tucson, AZ 85724, USA
N Engl J Med 354:1985-97. 2006..It is unknown whether inhaled corticosteroids can modify the subsequent development of asthma in preschool children at high risk for asthma... - Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialistsMichael Schatz
Kaiser Permanente Medical Center, San Diego, CA 92111, USA
J Allergy Clin Immunol 117:549-56. 2006..The development of the Asthma Control Test (ACT), a short, simple, patient-based tool for identifying patients with poorly controlled asthma, was recently described in patients under the routine care of an asthma specialist...