Affiliation: University of California
Song R, Murphy M, Li C, Ting K, Soo C, Zheng Z. Current development of biodegradable polymeric materials for biomedical applications. Drug Des Devel Ther. 2018;12:3117-3145 pubmed publisher
..This review outlines the current development of biodegradable natural and synthetic polymeric materials for various biomedical applications, including tissue engineering, temporary implants, wound healing, and drug delivery. ..
Kwak J, Zhang Y, Park J, Chen E, Shen J, Chawan C, et al
. Pharmacokinetics and osteogenic potential of PEGylated NELL-1 in vivo after systemic administration. Biomaterials. 2015;57:73-83 pubmed publisher
..Our findings suggest that the PEGylation technique presents a viable and promising approach to further develop NELL-1 into an effective systemic therapeutic for the treatment of osteoporosis. ..
Li C, Zheng Z, Zhang X, Asatrian G, Chen E, Song R, et al
. Nfatc1 Is a Functional Transcriptional Factor Mediating Nell-1-Induced Runx3 Upregulation in Chondrocytes. Int J Mol Sci. 2018;19: pubmed publisher
Li C, Jiang J, Zheng Z, Lee K, Zhou Y, Chen E, et al
. Neural EGFL-Like 1 Is a Downstream Regulator of Runt-Related Transcription Factor 2 in Chondrogenic Differentiation and Maturation. Am J Pathol. 2017;187:963-972 pubmed publisher
..Nell-1 is a key functional mediator of chondrogenesis, thus opening up new possibilities for the application of Nell-1 in cartilage regeneration. ..
Zhang L, Chang L, Xu J, Meyers C, Yan N, Zou E, et al
. Frontal Bone Healing Is Sensitive to Wnt Signaling Inhibition via Lentiviral-Encoded Beta-Catenin Short Hairpin RNA. Tissue Eng Part A. 2018;: pubmed publisher
Shen J, James A, Zhang X, Pang S, Zara J, Asatrian G, et al
. Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2. Am J Pathol. 2016;186:419-34 pubmed publisher
..The novel abilities of NELL-1 to stimulate Wnt signaling and to repress adipogenesis may highlight new treatment approaches for bone loss in osteoporosis. ..
Li C, Yang P, Ting K, Aghaloo T, Lee S, Zhang Y, et al
. Fibromodulin reprogrammed cells: A novel cell source for bone regeneration. Biomaterials. 2016;83:194-206 pubmed publisher
..Taken together, we have provided an extended potency, safety, and molecular profile of FReP cell-based bone regeneration. Therefore, FReP cells present a high potential for cellular and gene therapy products for bone regeneration. ..
Zheng Z, Zhang X, Dang C, Beanes S, Chang G, Chen Y, et al
. Fibromodulin Is Essential for Fetal-Type Scarless Cutaneous Wound Healing. Am J Pathol. 2016;186:2824-2832 pubmed publisher
Li C, Zheng Z, Jiang J, Jiang W, Lee K, Berthiaume E, et al
. Neural EGFL-Like 1 Regulates Cartilage Maturation through Runt-Related Transcription Factor 3-Mediated Indian Hedgehog Signaling. Am J Pathol. 2018;188:392-403 pubmed publisher