William Sonntag

Summary

Affiliation: University of Oklahoma Health Sciences Center
Country: USA

Publications

  1. pmc Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia
    Junie P Warrington
    Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
    PLoS ONE 7:e30444. 2012
  2. pmc Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1
    Ferenc Deak
    Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
    J Gerontol A Biol Sci Med Sci 67:611-25. 2012
  3. pmc Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies
    William E Sonntag
    Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Stanton L Young Biomedical Research Center 1303, 975 NE 10th Street, Oklahoma City, OK 74104, USA
    J Gerontol A Biol Sci Med Sci 67:587-98. 2012
  4. pmc Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment
    Heather D VanGuilder
    Department of Pharmacology, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, Pennsylvania 17057, USA
    J Neuroinflammation 8:138. 2011
  5. pmc Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice
    Junie P Warrington
    Oklahoma Center for Neuroscience, Oklahoma Center on Aging, Donald W Reynolds Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Am J Physiol Heart Circ Physiol 300:H736-44. 2011

Research Grants

Collaborators

  • Anna Csiszar
  • Luigi Ferrucci
  • Junie P Warrington
  • Ferenc Deak
  • Yong Woo Lee
  • Heather D VanGuilder
  • Matthew Mitschelen
  • Salahuddin Ahmad
  • Han Yan
  • Daniel A Johnson
  • Terence S Herman
  • Robert M Brucklacher
  • Willard M Freeman
  • Georgina V Bixler
  • Julie A Farley

Detail Information

Publications6

  1. pmc Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia
    Junie P Warrington
    Oklahoma Center for Neuroscience, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
    PLoS ONE 7:e30444. 2012
    ....
  2. pmc Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1
    Ferenc Deak
    Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA
    J Gerontol A Biol Sci Med Sci 67:611-25. 2012
    ..Further studies that detail the specific actions of this important neurotrophic hormone will likely lead to therapies that result in improved cognitive function for the elderly patients...
  3. pmc Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies
    William E Sonntag
    Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Stanton L Young Biomedical Research Center 1303, 975 NE 10th Street, Oklahoma City, OK 74104, USA
    J Gerontol A Biol Sci Med Sci 67:587-98. 2012
    ....
  4. pmc Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment
    Heather D VanGuilder
    Department of Pharmacology, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, Pennsylvania 17057, USA
    J Neuroinflammation 8:138. 2011
    ..This study sought to comprehensively investigate expression of the MHC II immune response pathway and glial activation in the hippocampus in the context of both aging and age-related cognitive decline...
  5. pmc Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice
    Junie P Warrington
    Oklahoma Center for Neuroscience, Oklahoma Center on Aging, Donald W Reynolds Department of Geriatric Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Am J Physiol Heart Circ Physiol 300:H736-44. 2011
    ..Our results indicate a potential shift in sensitivity to angiogenic stimuli and/or the existence of an independent pathway of regulating cerebral microvasculature...

Research Grants10

  1. Growth Hormone, IGF-1 and Age-related Pathogenesis
    William Sonntag; Fiscal Year: 2001
    ..In addition, the results will provide important information on the potential risks of administration of growth hormone and IGF-l to the elderly. ..
  2. Effects of Radiation on Brain Microvasculature and Cognition
    William Edmund Sonntag; Fiscal Year: 2010
    ..These procedures will allow us to make more precise conclusions related to the etiology of cognitive impairment that occurs in response to WBI and assess the efficacy of interventions to reduce cognitive impairment after radiation. ..
  3. Cognitive Decline & Protein Expression Profiles in Aging
    William Sonntag; Fiscal Year: 2009
    ..The results will provide the first comprehensive investigation of age-related changes in the proteome in discrete brain regions that contributes to cognitive deficits with age. ..
  4. Effects of Radiation on Brain Microvasculature and Cognition
    William Sonntag; Fiscal Year: 2009
    ..These procedures will allow us to make more precise conclusions related to the etiology of cognitive impairment that occurs in response to WBI and assess the efficacy of interventions to reduce cognitive impairment after radiation. ..
  5. Growth Hormone, IGF-1 and Age-related Pathogenesis
    William Sonntag; Fiscal Year: 2003
    ..In addition, the results will provide important information on the potential risks of administration of growth hormone and IGF-l to the elderly. ..
  6. Growth Hormone, IGF-1 and Age-related Pathogenesis
    William Sonntag; Fiscal Year: 2002
    ..In addition, the results will provide important information on the potential risks of administration of growth hormone and IGF-l to the elderly. ..
  7. Cognitive Decline & Protein Expression Profiles in Aging
    William Edmund Sonntag; Fiscal Year: 2010
    ..The results will provide the first comprehensive investigation of age-related changes in the proteome in discrete brain regions that contributes to cognitive deficits with age. ..