Paul Soloff

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Effects of serotonin-2A receptor binding and gender on personality traits and suicidal behavior in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Electronic address
    Psychiatry Res 222:140-8. 2014
  2. ncbi request reprint Impulsivity, aggression and brain structure in high and low lethality suicide attempters with borderline personality disorder
    Paul Soloff
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA Electronic address
    Psychiatry Res 222:131-9. 2014
  3. pmc Subtyping borderline personality disorder by suicidal behavior
    Paul H Soloff
    University of Pittsburgh
    J Pers Disord 26:468-80. 2012
  4. pmc Prospective predictors of suicidal behavior in borderline personality disorder at 6-year follow-up
    Paul H Soloff
    Department of Psychiatry, School of Medicine, University of Pittsburgh, PA, USA
    Am J Psychiatry 169:484-90. 2012
  5. pmc Structural brain abnormalities and suicidal behavior in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, United States
    J Psychiatr Res 46:516-25. 2012
  6. pmc Structural brain abnormalities in borderline personality disorder: a voxel-based morphometry study
    Paul Soloff
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Psychiatry Res 164:223-36. 2008
  7. doi request reprint Mediators of the relationship between childhood sexual abuse and suicidal behavior in borderline personality disorder
    Paul H Soloff
    University of Pittsburgh, USA
    J Pers Disord 22:221-32. 2008
  8. doi request reprint Prospective predictors of suicide attempts in borderline personality disorder at one, two, and two-to-five year follow-up
    Paul H Soloff
    School of Medicine, University of Pittsburgh, Pittsburgh, USA
    J Pers Disord 22:123-34. 2008
  9. ncbi request reprint 5HT2A receptor binding is increased in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Biol Psychiatry 62:580-7. 2007
  10. ncbi request reprint High-lethality status in patients with borderline personality disorder
    Paul H Soloff
    University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Pers Disord 19:386-99. 2005

Detail Information

Publications19

  1. ncbi request reprint Effects of serotonin-2A receptor binding and gender on personality traits and suicidal behavior in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Electronic address
    Psychiatry Res 222:140-8. 2014
    ..Vulnerability to suicidal behavior in BPD may be related to serotonin-2A binding through expression of personality risk factors. ..
  2. ncbi request reprint Impulsivity, aggression and brain structure in high and low lethality suicide attempters with borderline personality disorder
    Paul Soloff
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA Electronic address
    Psychiatry Res 222:131-9. 2014
    ..Lethality of suicide attempts in BPD may be related to the mediation of these personality traits by specific neural networks. ..
  3. pmc Subtyping borderline personality disorder by suicidal behavior
    Paul H Soloff
    University of Pittsburgh
    J Pers Disord 26:468-80. 2012
    ..Illness severity, older age, and poor psychosocial function are characteristics of a poor prognosis subtype related to suicidal behavior...
  4. pmc Prospective predictors of suicidal behavior in borderline personality disorder at 6-year follow-up
    Paul H Soloff
    Department of Psychiatry, School of Medicine, University of Pittsburgh, PA, USA
    Am J Psychiatry 169:484-90. 2012
    ..The authors conducted a longitudinal study of suicidal behavior in borderline personality disorder patients to identify prospective predictors of suicide attempts and to characterize those patients at highest risk for suicide completion...
  5. pmc Structural brain abnormalities and suicidal behavior in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, United States
    J Psychiatr Res 46:516-25. 2012
    ..We compared BPD suicide attempters and non-attempters, high and low lethality attempters to healthy controls to identify neural circuits associated with suicidal behavior in BPD...
  6. pmc Structural brain abnormalities in borderline personality disorder: a voxel-based morphometry study
    Paul Soloff
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Psychiatry Res 164:223-36. 2008
    ..Group differences varied greatly by gender, levels of depression, and impulsivity. VBM is an efficient method for exploratory study of brain-behavior relationships...
  7. doi request reprint Mediators of the relationship between childhood sexual abuse and suicidal behavior in borderline personality disorder
    Paul H Soloff
    University of Pittsburgh, USA
    J Pers Disord 22:221-32. 2008
    ..A theoretical model for suicidal behavior in BPD is presented which integrates direct, mediated, and moderated pathways between childhood sexual abuse and temperament, adolescent and adult risk factors, and suicidal behavior...
  8. doi request reprint Prospective predictors of suicide attempts in borderline personality disorder at one, two, and two-to-five year follow-up
    Paul H Soloff
    School of Medicine, University of Pittsburgh, Pittsburgh, USA
    J Pers Disord 22:123-34. 2008
    ..Assessing and supporting family, work, and social relationships may decrease suicidal behavior in BPD, and should be a principal focus of long-term treatment...
  9. ncbi request reprint 5HT2A receptor binding is increased in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Biol Psychiatry 62:580-7. 2007
    ..We examined 5HT(2A) receptor binding potential (BP) in impulsive subjects with BPD, with positron emission tomography neuroimaging with [(18)F] altanserin...
  10. ncbi request reprint High-lethality status in patients with borderline personality disorder
    Paul H Soloff
    University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Pers Disord 19:386-99. 2005
    ..These characteristics resemble profiles of patients who complete suicide, are not specific for BPD, and do not include impulsivity, aggression, or severity of BPD criteria...
  11. pmc Gender, personality, and serotonin-2A receptor binding in healthy subjects
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Psychiatry Res 181:77-84. 2010
    ..Future studies of 5HT(2A) receptor function and its relationship to behavior should control for gender...
  12. ncbi request reprint Clinical outcome of ECT in patients with major depression and comorbid borderline personality disorder
    Ulrike Feske
    Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Am J Psychiatry 161:2073-80. 2004
    ..The authors compared the acute outcome of ECT in depressed patients with borderline personality disorder, with personality disorders other than borderline personality disorder, and with no personality disorder...
  13. ncbi request reprint Anatomical MRI study of borderline personality disorder patients
    Paolo Brambilla
    Division of Mood and Anxiety Disorders, Department of Psychiatry, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Psychiatry Res 131:125-33. 2004
    ..Early traumatic experiences may play a role in hippocampal atrophy, whereas substance use disorders may contribute to putamen enlargement...
  14. ncbi request reprint Efficacy and tolerability of olanzapine in the treatment of schizotypal personality disorder
    Matcheri Keshavan
    University of Pittsburgh Medical Center, Health System Western Psychiatric Institute and Clinic, Room 984, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Schizophr Res 71:97-101. 2004
    ..This study examined the efficacy and tolerability of olanzapine, an atypical antipsychotic drug, in a series of patients with DSM-IV diagnosed schizotypal personality disorder...
  15. ncbi request reprint Childhood abuse as a risk factor for suicidal behavior in borderline personality disorder
    Paul H Soloff
    Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh, USA
    J Pers Disord 16:201-14. 2002
    ..Given a history of childhood sexual abuse, the risk of adult suicidal behavior in BPD was increased by antisocial traits, severity of BPD, hopelessness, or comorbid major depressive episode (MDE)...
  16. ncbi request reprint Gender differences in a fenfluramine-activated FDG PET study of borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Psychiatry Res 138:183-95. 2005
    ..Gender differences in serotonergic function may mediate differences in behavioral expression of impulsive aggression in subjects with BPD...
  17. ncbi request reprint Impulsivity and prefrontal hypometabolism in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Psychiatry Res 123:153-63. 2003
    ..Decreased glucose uptake in medial orbital frontal cortex may be associated with diminished regulation of impulsive behavior in BPD...
  18. ncbi request reprint Impulsivity, gender, and response to fenfluramine challenge in borderline personality disorder
    Paul H Soloff
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA, USA
    Psychiatry Res 119:11-24. 2003
    ..Impulsivity and aggression were inversely related to delta-prolactin and peak-prolactin responses among male but not female subjects. Gender differences in central serotonergic function may contribute to variations in impulsivity in BPD...
  19. ncbi request reprint MRI study of corpus callosum in patients with borderline personality disorder: a pilot study
    Marcus V Zanetti
    Laboratory of Psychiatric Neuroimaging LIM 21, Department and Institute of Psychiatry, University of Sao Paulo, Sao Paulo, SP, Brazil
    Prog Neuropsychopharmacol Biol Psychiatry 31:1519-25. 2007
    ..Abnormalities in interhemispheric connectivity do not appear necessary for the development of BPD. Further studies with larger samples are needed to confirm this preliminary finding...

Research Grants17

  1. PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BORDERLINE PERSONALITY DISORDER
    Paul Soloff; Fiscal Year: 2009
    ..Neuroimaging data will be tested with other clinical variables for significance in predicting suicidal behavior in an effort to identify biologic "markers" in individuals at highest risk ..
  2. PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BORDERLINE PERSONALITY DISORDER
    Paul Soloff; Fiscal Year: 2007
    ..Neuroimaging data will be tested with other clinical variables for significance in predicting suicidal behavior in an effort to identify biologic "markers" in individuals at highest risk ..
  3. Psychobiology of Suicidal Behavioral in BPD
    Paul Soloff; Fiscal Year: 2005
    ..Risk factors predicting recurrence and medical lethality of attempts will allow early identification of BPD patients at highest risk for suicide and inform treatment efforts. ..
  4. Psychobiology of Suicidal Behavioral in BPD
    Paul Soloff; Fiscal Year: 2004
    ..Risk factors predicting recurrence and medical lethality of attempts will allow early identification of BPD patients at highest risk for suicide and inform treatment efforts. ..
  5. Psychobiology of Suicidal Behavioral in BPD
    Paul Soloff; Fiscal Year: 2003
    ..Risk factors predicting recurrence and medical lethality of attempts will allow early identification of BPD patients at highest risk for suicide and inform treatment efforts. ..
  6. Psychobiology of Suicidal Behavioral in BPD
    Paul Soloff; Fiscal Year: 2002
    ..Risk factors predicting recurrence and medical lethality of attempts will allow early identification of BPD patients at highest risk for suicide and inform treatment efforts. ..
  7. Psychobiology of Suicidal Behavioral in BPD
    Paul Soloff; Fiscal Year: 2001
    ..Risk factors predicting recurrence and medical lethality of attempts will allow early identification of BPD patients at highest risk for suicide and inform treatment efforts. ..
  8. PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPD
    Paul Soloff; Fiscal Year: 2000
    ....
  9. PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPD
    Paul Soloff; Fiscal Year: 1993
    ....
  10. PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPD
    Paul Soloff; Fiscal Year: 1992
    ....
  11. PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPD
    Paul Soloff; Fiscal Year: 1999
    ....
  12. PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BORDERLINE PERSONALITY DISORDER
    Paul H Soloff; Fiscal Year: 2010
    ..Neuroimaging data will be tested with other clinical variables for significance in predicting suicidal behavior in an effort to identify biologic "markers" in individuals at highest risk ..