Research Topics
| L J SolinSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Primary mucosa-associated lymphoid tissue lymphoma of the breastRamji R Rajendran
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA
Clin Breast Cancer 8:187-8. 2008..Herein, a case is presented of a patient with primary MALT lymphoma of the breast. Issues in diagnosis and breast-conservation treatment, as it pertains to primary MALT lymphoma of the breast, will be discussed...
Salvage treatment for local recurrence after breast-conserving surgery and radiation as initial treatment for mammographically detected ductal carcinoma in situ of the breastL J Solin
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Cancer 91:1090-7. 2001....
Salvage treatment for local or local-regional recurrence after initial breast conservation treatment with radiation for ductal carcinoma in situLawrence J Solin
Department of Radiation Oncology, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
Eur J Cancer 41:1715-23. 2005..Close follow-up after initial breast conservation treatment with radiation is warranted for the early detection of potentially salvageable local and local-regional recurrences...
Long-term outcome after breast-conservation treatment with radiation for mammographically detected ductal carcinoma in situ of the breastLawrence J Solin
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Cancer 103:1137-46. 2005..The objective of the current study was to determine the long-term outcome after breast-conservation surgery followed by definitive breast irradiation for women with mammographically detected DCIS of the breast...
Relationship of breast magnetic resonance imaging to outcome after breast-conservation treatment with radiation for women with early-stage invasive breast carcinoma or ductal carcinoma in situLawrence J Solin
Department of Radiation Oncology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
J Clin Oncol 26:386-91. 2008..To determine the relationship of breast magnetic resonance imaging (MRI) to outcome after breast-conservation treatment (BCT) with radiation for women with early-stage invasive breast carcinoma or ductal carcinoma in situ...
Mammographically detected ductal carcinoma in situ of the breast treated with breast-conserving surgery and definitive breast irradiation: long-term outcome and prognostic significance of patient age and margin statusL J Solin
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 50:991-1002. 2001....
Similar long-term results of breast-conservation treatment for Stage I and II invasive lobular carcinoma compared with invasive ductal carcinoma of the breast: The University of Pennsylvania experienceRoberto J Santiago
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Cancer 103:2447-54. 2005..40). CONCLUSIONS: Breast-conservation treatment yielded similar long-term results for women with early-stage, invasive lobular carcinoma and women with the more prevalent invasive ductal carcinoma...
Relationship of family history and outcome after breast conservation therapy in women with ductal carcinoma in situ of the breastE E Harris
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 48:933-41. 2000....
Late cardiac mortality and morbidity in early-stage breast cancer patients after breast-conservation treatmentEleanor E R Harris
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Clin Oncol 24:4100-6. 2006..This study was undertaken as a comprehensive examination of the long-term cardiac mortality and morbidity after breast irradiation using contemporary irradiation techniques...
Effect of radiotherapy after breast-conserving treatment in women with breast cancer and germline BRCA1/2 mutationsL J Pierce
Department of Radiation Oncology, University of Michigan, and University of Michigan Cancer Center Biostatistics Core, Ann Arbor, MI, USA
J Clin Oncol 18:3360-9. 2000....
Coronary artery findings after left-sided compared with right-sided radiation treatment for early-stage breast cancerCandace R Correa
Department of Radiation Oncology, Radiology Cardiovascular Imaging Section, Medicine Division of Cardiovascular Medicine, and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
J Clin Oncol 25:3031-7. 2007....
Breast conservation treatment for patients presenting with axillary lymphadenopathy from presumed primary breast cancer: the role of breast magnetic resonance imaging for stagingChanghu Chen
Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
Clin Breast Cancer 3:219-22. 2002..These 3 cases illustrate the potential for breast conservation treatment for patients presenting with axillary adenopathy from a presumed primary breast cancer but without either mammographic or breast MRI findings...
Outcomes in breast cancer patients relative to margin status after treatment with breast-conserving surgery and radiation therapy: the University of Pennsylvania experienceM E Peterson
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, USA
Int J Radiat Oncol Biol Phys 43:1029-35. 1999..To evaluate the significance of final microscopic resection margin status on treatment outcomes in women with early breast cancer who are treated with breast-conserving surgery and definitive breast irradiation...
Fifteen-year results of breast-conserving surgery and definitive irradiation for Stage I and II breast carcinoma: the University of Pennsylvania experienceRoberto J Santiago
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 58:233-40. 2004..CONCLUSION: These high rates of survival and local control confirm that breast conservation therapy yields favorable results in women with early breast cancer into the second decade after treatment...
Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancerLori J Pierce
Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI 48109 0010, USA
J Clin Oncol 24:2437-43. 2006..We compared the outcome of breast-conserving surgery and radiotherapy in BRCA1/2 mutation carriers with breast cancer versus that of matched sporadic controls...
Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk breast carcinomaKevin J Downes
Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Cancer 103:906-13. 2005....
Conservative management of Paget disease of the breast with radiotherapy: 10- and 15-year resultsJennifer K Marshall
Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA
Cancer 97:2142-9. 2003....
The impact of comorbidities on outcomes for elderly women treated with breast-conservation treatment for early-stage breast cancerEleanor E R Harris
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Int J Radiat Oncol Biol Phys 70:1453-9. 2008..Breast cancer incidence increases with age and is a major cause of morbidity and mortality in elderly women, but is not well studied in this population. Comorbidities often impact on the management of breast cancer in elderly women...
Outcome after breast conservation treatment with radiation for women with triple-negative early-stage invasive breast carcinomaLawrence J Solin
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19141, USA
Clin Breast Cancer 9:96-100. 2009..The current study was performed to determine the relationship of triple-negative tumor status to outcome after breast conservation treatment with radiation...
Outcomes after breast conservation treatment with radiation in women with prior nonbreast malignancy and subsequent invasive breast carcinomaDeepika Nemani
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 73:1055-60. 2009..This report analyzes the outcomes in patients with Stage I and II breast cancer after breast conservation treatment (BCT) with a prior nonbreast malignancy...
Decision-analytic model and cost-effectiveness evaluation of postmastectomy radiation therapy in high-risk premenopausal breast cancer patientsJason H Lee
Department of Radiation Oncology, Division of General Internal Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA
J Clin Oncol 20:2713-25. 2002..To present a decision model that describes the clinical and economic outcomes of node-positive breast cancer with and without postmastectomy radiation therapy (PMRT)...
Breast MR imaging in patients with axillary node metastases and unknown primary malignancyS G Orel
Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
Radiology 212:543-9. 1999..To assess the usefulness of magnetic resonance (MR) imaging of the breast in patients with malignant axillary adenopathy and unknown primary malignancy...
Effect of time interval between surgery and preoperative chemoradiotherapy with 5-fluorouracil or 5-fluorouracil and oxaliplatin on outcomes in rectal cancerC M Dolinsky
Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Surg Oncol 96:207-12. 2007..Preoperative chemoradiotherapy for locally advanced rectal cancer is now considered "standard of care." However, the optimal time interval for resection after neoadjuvant therapy is unknown...
Twenty-year incidence and patterns of contralateral breast cancer after breast conservation treatment with radiationChristine E Hill-Kayser
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 66:1313-9. 2006..This study was undertaken to determine the incidence of contralateral breast cancer (CLB) after treatment for early-stage breast cancer with breast-conserving treatment (BCT), and to observe patterns of CLB presentation...
Choice of beam energy and dosimetric implications for radiation treatment in a subpopulation of women with large breasts in the United States and JapanIndra J Das
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Med Dosim 31:216-23. 2006..Simple guidelines are provided for dose uniformity in breast with respect to chest wall separation, body weight, bra size, and breast volume with tangential field irradiations...
Extensive retraction artifact correlates with lymphatic invasion and nodal metastasis and predicts poor outcome in early stage breast carcinomaGeza Acs
Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Am J Surg Pathol 31:129-40. 2007..Rather, it likely signifies important biologic changes that alter tumor-stromal interactions and contribute to lymphatic spread and tumor progression...
Method of primary tumor detection as a risk factor for local and distant recurrence after breast-conservation treatment for early-stage breast cancerJulia Tchou
Department of Surgery, Division of Endocrine and Oncologic Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
Clin Breast Cancer 8:143-8. 2008....
Biopsy findings after breast conservation therapy for early-stage invasive breast cancerNeha Vapiwala
Department of Radiation Oncology, Hospital of University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 69:490-7. 2007..To determine the patterns and factors predictive of positive ipsilateral breast biopsy after conservation therapy for early-stage breast cancer...
Time course of mild arm lymphedema after breast conservation treatment for early-stage breast cancerVoichita Bar Ad
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 76:85-90. 2010..Arm lymphedema is a potential consequence of the treatment for breast carcinoma. The objective of this retrospective study was to characterize the progression of mild arm lymphedema after breast conservation treatment for breast cancer...
Lymphedema in breast cancer survivors: incidence, degree, time course, treatment, and symptomsSandra A Norman
Department of Medicine, Division of Hematology Oncology, Center for Clinical Epidemiologyand Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Oncol 27:390-7. 2009..To examine the incidence, degree, time course, treatment, and symptoms of lymphedema in breast cancer survivors...
Risk factors for lymphedema after breast cancer treatmentSandra A Norman
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Cancer Epidemiol Biomarkers Prev 19:2734-46. 2010..As cancer treatments evolve, it is important to reevaluate their effect on lymphedema risk in breast cancer survivors...
Mammographic appearance of recurrent breast cancer after breast conservation therapySusan P Weinstein
Department of Radiology, University of Pennsylvania Health System, 3400 Spruce Street, Philadelphia, PA 19104, USA
Acad Radiol 15:240-4. 2008..To compare the mammographic appearance of recurrent breast cancer to the primary tumor in patients treated with breast conservation therapy...
Long-term outcome for mammographically detected ductal carcinoma in situ managed with breast conservation treatment: prognostic significance of reexcisionNeha Vapiwala
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Cancer J 12:25-32. 2006....
Ten-year outcome after combined modality therapy for inflammatory breast cancerEleanor E R Harris
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 55:1200-8. 2003..To evaluate the long-term outcome of combined modality therapy for inflammatory breast cancer...
Prognosis after regional lymph node recurrence in patients with stage I-II breast carcinoma treated with breast conservation therapyEleanor E R Harris
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Cancer 98:2144-51. 2003..The authors evaluated the risk factors for regional lymph node recurrence and the prognosis of patients with regional nodal recurrence after breast conservation therapy for Stage I-II breast carcinoma...
Factors associated with residual disease on re-excision in patients with ductal carcinoma in situ of the breastEleanor E R Harris
Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Cancer J 9:42-8. 2003..This study examines the factors associated with the presence of residual disease at re-excision in patients with ductal carcinoma in situ of the breast...
Impact of concurrent versus sequential tamoxifen with radiation therapy in early-stage breast cancer patients undergoing breast conservation treatmentEleanor E R Harris
Department of Radiaton Oncology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
J Clin Oncol 23:11-6. 2005..To assess the impact of sequencing of tamoxifen and radiation therapy (RT) on outcomes in early-stage breast cancer...
Transmission and dose perturbations with high-Z materials in clinical electron beamsIndra J Das
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Med Phys 31:3213-21. 2004..Caution should be given to clinicians for the selection of thickness of high-Z materials when used to shield critical structures as small thickness increases dose significantly at interfaces...
Regional nodal recurrence after breast conservation treatment with radiotherapy for women with early-stage breast carcinomaJ Nicholas Lukens
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 73:1475-81. 2009..To report the long-term outcomes for women presenting with regional lymph node recurrence after breast conservation treatment with radiotherapy for Stage I and II invasive breast carcinoma...
MR imaging screening of the contralateral breast in patients with newly diagnosed breast cancer: preliminary resultsSteven G Lee
Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
Radiology 226:773-8. 2003..To investigate the role of screening magnetic resonance (MR) imaging in the detection of synchronous contralateral breast cancer in patients with newly diagnosed breast cancer...
Paget's disease of the nipple as local recurrence after breast-conservation treatment for early-stage breast cancerJohn P Plastaras
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Clin Breast Cancer 6:349-53. 2005..9, 10.6, 3.1, and 3.8 years. Paget's disease as local recurrence after BCT is uncommon and can be treated with salvage therapy if detected early...
Long-term results of local recurrence after breast conservation treatment for invasive breast cancerT Doyle
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 51:74-80. 2001..Second local recurrence after salvage mastectomy is an uncommon event. Although DCIS local recurrences may not in themselves cause an increase in the risk of mortality, the risk from the primary invasive cancer persists...
Outcome after treatment of patients with mammographically occult, magnetic resonance imaging-detected breast cancer presenting with axillary lymphadenopathyChanghu Chen
Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
Clin Breast Cancer 5:72-7. 2004....
Cardiac morbidity and mortality after breast conservation treatment in patients with early-stage breast cancer and preexisting cardiac diseaseRuchika Gutt
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, USA
Clin Breast Cancer 8:443-8. 2008..This study was undertaken to determine the risk of late cardiac morbidity and mortality in patients with preexisting cardiac disease treated with contemporary radiation techniques for early-stage breast cancer...
MRI before reexcision surgery in patients with breast cancerJanie M Lee
Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
AJR Am J Roentgenol 182:473-80. 2004..All patients underwent contrast-enhanced MRI before further surgery and subsequently underwent either reexcision lumpectomy or mastectomy with histopathologic correlation...
Counterview: Pre-operative breast MRI (magnetic resonance imaging) is not recommended for all patients with newly diagnosed breast cancerLawrence J Solin
Department of Radiation Oncology, Albert Einstein Medical Center, 5501 Old York Road, Philadelphia, PA 19141, USA
Breast 19:7-9. 2010..In summary, the routine use of pre-operative breast MRI is not warranted for the typical patient with a newly diagnosed early stage breast cancer...
Proceedings of the Consensus Conference on Breast Conservation, April 28 to May 1, 2005, Milan, ItalyGordon F Schwartz
Department of Surgery, Jefferson Medical College, Philadelphia, Pennsylvania 19107-4305, USA
Cancer 107:242-50. 2006
The impact of HER-2 status on local recurrence in women with stage I-II breast cancer treated with breast-conserving therapyEleanor E R Harris
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA
Breast J 12:431-6. 2006..15). There was no difference in local recurrence after BCT between HER-2-positive and negative breast cancers at 5 years. Therefore HER-2 overexpression does not appear to be a contraindication to BCT...
American College of Radiology appropriateness criteria on conservative surgery and radiation: stages I and II breast carcinomaJulia R White
Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 4801, USA
J Am Coll Radiol 5:701-13. 2008..Successful breast conservation relies on understanding key elements for patient selection, evaluation, treatment contraindications, radiation therapy methods, and integration with systemic therapy...
Relation between the method of detection of initial breast carcinoma and the method of detection of subsequent ipsilateral local recurrence and contralateral breast carcinomaChanghu Chen
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Cancer 98:1596-602. 2003....
Accelerated partial breast irradiation : a legitimate treatment option?Lawrence J Solin
Department of Radiation Oncology, University of Pennsylvania, PA, USA
Clin Breast Cancer 4:379. 2004
Efficacy of radiotherapy for ovarian ablation: results of a breast intergroup studyLorie L Hughes
Department of Radiation Oncology, WellStar Kennestone Hospital, Marietta, GA 30060, USA
Cancer 101:969-72. 2004..In the current study, we report the efficacy of pelvic RT with this dose-fractionation scheme in the induction of ovarian ablation...
Analysis of interfraction and intrafraction variation during tangential breast irradiation with an electronic portal imaging deviceRyan P Smith
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 62:373-8. 2005....
Outcomes after breast conservation treatment with radiation in women with ductal carcinoma in situ and prior nonbreast malignancyDeepika N Shah
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Breast J 15:649-52. 2009..In this cohort of 14 patients treated for DCIS of the breast after a prior nonbreast malignancy, treatment for DCIS resulted in a high rate of local control and should be considered for curative intent...
Effect of breast magnetic resonance imaging on the clinical management of women with early-stage breast carcinomaGayle F Tillman
Department of Radiation Oncology, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
J Clin Oncol 20:3413-23. 2002..0089). CONCLUSIONS: Breast MRI alters the clinical management for a sizable fraction of women with early-stage breast cancer and appears to offer clinically useful information for determining optimal local treatment...
The impact of a multidisciplinary breast cancer center on recommendations for patient management: the University of Pennsylvania experienceJ H Chang
Department of Radiation Oncology, University of Pennsylvania Cancer Center and School of Medicine, Philadelphia, Pennsylvania, USA
Cancer 91:1231-7. 2001..This multidisciplinary program provided important second opinions for many patients with breast carcinoma...
Proceedings of the international consensus conference on breast cancer risk, genetics, & risk management, April, 2007Gordon F Schwartz
Jefferson Medical College, 1015 Chestnut Street, Suite 510, Philadelphia, PA 19107 4305, USA
Breast J 15:4-16. 2009..These risk reduction strategies were evaluated fully, and recommendations were made for the care of patients in each of the risk categories. These guidelines for patient care were approved by the entire group of experts...
Association between tangential beam treatment parameters and cardiac abnormalities after definitive radiation treatment for left-sided breast cancerCandace R Correa
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 72:508-16. 2008....
Proceedings of the international consensus conference on breast cancer risk, genetics, & risk management, April, 2007Gordon F Schwartz
Department of Surgery, Jefferson Medical College, Philadelphia, Pennsylvania, USA
Cancer 113:2627-37. 2008..These risk reduction strategies were evaluated fully, and recommendations were made for the care of patients in each risk category. These guidelines for patient care were approved by the entire group of experts...
Is excision alone adequate treatment for low-risk ductal carcinoma-in-situ of the breast?Lawrence J Solin
J Clin Oncol 24:1017-9. 2006
Consensus conference on breast conservationGordon F Schwartz
J Am Coll Surg 203:198-207. 2006
