AMR SOLIMAN

..In this pilot study, we evaluate BPA exposure and assess likely pathways of exposure among girls from urban and rural Egypt...

..The exposure to phthalates in premenstrual Egyptian females remains unknown. The objective of this study was to characterize phthalate exposure of a potentially vulnerable population of premenstrual girls from urban and rural Egypt...

..Evaluation-guided future plans for the program include implementing faculty development to further enhance the program outcomes...

..Lifestyle factors and environmental exposures might help explain the risk of colorectal carcinoma in countries where the incidence is low, but unique patterns of young onset and a high proportion of rectal cancer exist...

..Variations in genetic mutations in pancreatic carcinoma between different geographical regions have not been studied extensively, especially in developing countries where pancreatic cancer is relatively rare...

..Because of availability of reliable mortality registration in Egypt, we used the national mortality data to estimate pancreatic cancer mortality in 2765 deaths from 2000 to 2004, and to gain insights into the disease incidence...

..Our study identifies that there are differences in the types of mutations found in tumors from pancreatic carcinoma patients in Egypt and the US, and suggests that environmental factors may explain these differences...

..Our data also warrant future studies of the association between water pollution and pancreatic cancer in the region...

..This study offers encouraging evidence of interest which focused in extramural education to augment skills facilitating cancer-related research in special populations...

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..Organochlorine serum level was not a risk factor of breast cancer in this population...

..To describe urban-rural differences in breast cancer incidence in Gharbiah, Egypt and to investigate if these differences could be explained by known risk factors of breast cancer...

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..Future studies should focus on relating epidemiologic factors to molecular features of IBC in this population...

..This study examined the epidemiology of pancreatic cancer in Egypt...

..The findings of our study are significant in further understanding the relationship of ER status and risk factors of breast cancer in the context of the Indian subcontinent...

..A higher frequency of IBC and a more aggressive IBC phenotype was reported in Egypt than in the United States. This difference in disease frequency and presentation might be related to molecular epidemiologic factors...

..The aim of this study was to investigate the efficiency of tribal linkages in enhancing the quality of racial information in state cancer registries...

..ER-incidence rate was 2-3 times (IRR = 1.86, 95% CI = 2.38, 1.45) higher in urban areas than in rural areas. Our findings indicate that urban women may probably have a higher exposure to xenoestrogens...

..Future studies on a larger sample size should investigate methylation profile in populations with higher rates of HBV, HCV, and other risk factors...

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..International collaborations are an essential step in facilitating this process, because it can improve cancer registries, create robust infrastructure, improve skills of personnel and lead to effective cancer control and prevention...

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..With the anticipated adoption of this module in Egypt and Tunisia, we expect to see more appropriate referrals to cancer centers. These results could guide future oncology CME for physicians in developing countries...

..The medical and health-related educational system in Egypt has many limitations, but it has the structure and inherent ability to achieve cancer education goals...

..In Egypt, the disease has traditionally been considered rare, and there has not been a previous publication on its population-based incidence or age distribution...

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..To evaluate temporal changes in histopathological types of bladder cancer and to assess associated changes in demographic, epidemiologic, and lifestyle risk factors...

..We aimed to evaluate liver diseases and sex steroid hormones in Egypt, which has the highest prevalence of HCV worldwide...

..RELEVANCE TO CLINICAL PRACTICE/PUBLIC HEALTH: Future studies should further investigate the etiologic relationship between cadmium exposure and pancreatic carcinogenesis in cadmium-exposed populations...

..These molecular differences could affect prevention strategies, therapeutic efficacy, and transferability of clinical trial results...

..The results from this study will provide clues about the etiology of pancreatic cancer. ..

..This study may define the role of cadmium in the etiology of pancreatic cancer and may set the stage for future studies on gene-environmental interactions in the epidemiology of pancreatic cancer. ..

..Together, the training in these three areas will provide the skills and experience necessary for an independent career as a molecular and genetic epidemiologist interested in colorectal cancer. ..

..With the large number of patients included in this study from Egypt and the U.S., we may be able develop a better idea about molecular pathways and prognostic factors in IBC pathogenesis. ..

..We plan to disseminate the program through partnerships with U.S.-based epidemiology programs that have the potential and interest in adopting our program. We plan dissemination workshops to implement these partnerships. ..