Research Topics
| T D SolbergSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Dynamic arc radiosurgery field shaping: a comparison with static field conformal and noncoplanar circular arcsT D Solberg
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, CA, USA
Int J Radiat Oncol Biol Phys 49:1481-91. 2001..In the latter, the MLC leaves more in a continuous fashion, conforming to the beam's-eye-view projection of the target at every increment along the path of an arc...
Image-guided radiotherapy using a mobile kilovoltage x-ray deviceStephen P Sorensen
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA
Med Dosim 31:40-50. 2006..It was demonstrated that this could be improved by correlating the acquisition of individual 2D projections with respiration for retrospective reconstruction of phase-based volumetric datasets...
Dosimetric parameters of three new solid core I-125 brachytherapy sourcesTimothy D Solberg
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 98095 6951, USA
J Appl Clin Med Phys 3:119-34. 2002..All dosimetric parameters were found to be in close agreement with previously published data for similar source configurations. The MCNP Monte Carlo code appears to be ideally suited to low energy dosimetry applications...
Functional stereotactic radiosurgery involving a dedicated linear accelerator and gamma unit: a comparison studyTimothy D Solberg
Department of Radiation Oncology, University of California, Los Angeles School of Medicine, Los Angeles 90095 6951, USA
J Neurosurg 101:373-80. 2004..The purpose of this work was to investigate the targeting and dosimetric characteristics of a linear accelerator (LINAC) system dedicated for stereotactic radiosurgery compared with those of a commercial gamma knife (GK) unit...
A feasibility study of 18F-fluorodeoxyglucose positron emission tomography targeting and simultaneous integrated boost for intensity-modulated radiosurgery and radiotherapyTimothy D Solberg
Department of Radiation Oncology, David Geffen School of Medicine, University of California, 90095 6951, USA
J Neurosurg 101:381-9. 2004....
Dosimetric characterization of an image-guided stereotactic small animal irradiatorR Pidikiti
Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA
Phys Med Biol 56:2585-99. 2011..5%. PDD data demonstrate typical increased penetration with increasing field size and SSD. For collimators larger than 5 mm in diameter, OFs measured using film, an ion chamber and a diode were within 3% agreement...
A CT-based Monte Carlo simulation tool for dosimetry planning and analysisJ J DeMarco
Jonsson Comprehensive Cancer Center, Department of Radiation Oncology, University of California Los Angeles, 90024 6951, USA
Med Phys 25:1-11. 1998..The dose distribution from a typical mediastinum treatment planning setup is presented for qualitative analysis and comparison versus a conventional treatment planning system...
CT-based dosimetry calculations for 125I prostate implantsJ J DeMarco
Department of Radiation Oncology, University of California, Los Angeles 90095 6951, USA
Int J Radiat Oncol Biol Phys 45:1347-53. 1999....
Radiosurgery and stereotactic radiation therapy of skull base meningiomas: proposal of a grading systemA A De Salles
Division of Neurosurgery and Department of Radiation Oncology, University of California, Los Angeles, CA 90095, USA
Stereotact Funct Neurosurg 76:218-29. 2001....
Stereotactic radiotherapy for the treatment of pituitary adenomasM T Selch
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
Minim Invasive Neurosurg 49:150-5. 2006..The aim of this study was to retrospectively review local control and morbidity following stereotactic radiotherapy (SRT) for pituitary adenoma...
A virtual source model for Monte Carlo modeling of arbitrary intensity distributionsI Chetty
Jonsson Comprehensive Cancer Center, Department of Radiation Oncology, University of California Los Angeles, 90024 6951, USA
Med Phys 27:166-72. 2000..53. Irregular field calculations compared with film measurement and with a 3-D pencil beam algorithm show that the source model is capable of accurately simulating arbitrary MLC fields...
Infrared patient positioning for stereotactic radiosurgery of extracranial tumorsL T Wang
School of Medicine, University of Southern California, 2108 Fair Park Avenue 111, Los Angeles, CA 90041, USA
Comput Biol Med 31:101-11. 2001..Experimental data was collected using a rigid torso phantom and correlated with theoretical results. The accuracy of the infrared system was compared with existing systems...
Radiosurgery performed with the aid of a 3-mm collimator in the subthalamic nucleus and substantia nigra of the vervet monkeyA A De Salles
Department of Surgery, University of California at Los Angeles School of Medicine, California 90095 6975, USA
J Neurosurg 95:990-7. 2001..Postmortem immunohistochemical studies were conducted to determine the extent of lesion-induced radiobiological effects...
An x-ray image guidance system for small animal stereotactic irradiationK H Song
Department of Radiation Oncology, UT Southwestern Medical Center at Dallas, Dallas, TX 75235, USA
Phys Med Biol 55:7345-62. 2010..The capabilities of 3D treatment and cone-beam computed tomography are presented for 3D localization and delivery as a work in progress...
Linear accelerator stereotactic radiosurgery for the treatment of gelastic seizures due to hypothalamic hamartomaM T Selch
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 6951, USA
Minim Invasive Neurosurg 48:310-4. 2005..The authors reviewed the results of linear accelerator (LINAC) radiosurgery for patients with medically refractory gelastic seizures due to a sessile hypothalamic hamartoma...
A Monte Carlo tutorial and the application for radiotherapy treatment planningJ J DeMarco
UCLA Department of Radiation Oncology, University of California Los Angeles, 90095 6951, USA
Med Dosim 27:43-50. 2002..The effects of statistical uncertainty on the Monte Carlo calculation are also presented...
Phase versus amplitude sorting of 4D-CT dataNicole Wink
Department of Radiation Oncology, David Geffen School of Medicine at University of California, Los Angeles, Peter Morton Medical Building, Suite B265, Los Angeles, California 90095 USA
J Appl Clin Med Phys 7:77-85. 2006..A 180 degrees interpolation was used for reconstruction after gating. Significant improvement using the amplitude-sorting technique was observed, particularly when testing nonperiodic motion functions...
Stereotactic radiosurgery of the rete mirabile in swine: a longitudinal study of histopathological changesReza Jahan
Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
Neurosurgery 58:551-8; discussion 551-8. 2006..The mechanisms of vessel occlusion in arteriovenous malformations has not been extensively evaluated. To better understand these mechanisms, we report histopathological changes in the swine rete mirabile after stereotactic radiosurgery...
Optimization of multi-slice helical respiration-correlated CT: the effects of table speed and rotation timeNicole M Wink
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Phys Med Biol 50:5717-29. 2005....
Dosimetric characteristics of a new linear accelerator under gated operationSergey Kriminski
Department of Radiation Oncology, David Geffen School of Medicine at University of California, Los Angeles, California 90095, USA
J Appl Clin Med Phys 7:65-76. 2006..Based on the comparison with widely accepted standards for conventional delivery, our results indicate that this LINAC is well suited for gated delivery of nondynamic fields...
Improvements in prostate brachytherapy dosimetry due to seed strandingKevin Lin
Department of Radiation Oncology, University of California, Los Angeles, CA 90095, USA
Brachytherapy 6:44-8. 2007..In order to contribute to the understanding of whether seed stranding improves dosimetry, we present retrospective data from our institution...
Quantifying the interplay effect in prostate IMRT delivery using a convolution-based methodHaisen S Li
Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, Nebraska 68198 7521, USA
Med Phys 35:1703-10. 2008..3%, in single fraction plans. For entire treatment courses delivered in either a hypofractionated (five fractions) or conventional (> 30 fractions) regimen, the discrepancy in total dose due to interplay effect was negligible...
Use of the BrainLAB ExacTrac X-Ray 6D system in image-guided radiotherapyJian Yue Jin
Department of Radiation Oncology, Henry Ford Health System, Detroit, MI 48202, USA
Med Dosim 33:124-34. 2008....
Stereotactic body radiation therapy: a new paradigm in radiotherapy management of cancerTimothy D Solberg
Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
J Am Coll Radiol 5:673-7. 2008
Quality assurance of immobilization and target localization systems for frameless stereotactic cranial and extracranial hypofractionated radiotherapyTimothy D Solberg
Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198 7521, USA
Int J Radiat Oncol Biol Phys 71:S131-5. 2008..In this report, we reviewed the technologies for frameless localization of cranial and extracranial targets with emphasis on the quality assurance aspects...
Experimental verification and clinical implementation of a commercial Monte Carlo electron beam dose calculation algorithmMargarida Fragoso
University of Nebraska Medical Center, Omaha, Nebraska 68198 7521, USA
Med Phys 35:1028-38. 2008..3 cm. Timing values ranged from 2 min to 24.5 h, depending on the field size, beam energy, number, and thickness of computed tomography slices used to define the patient's anatomy for the overall uncertainty values mentioned above...
Dosimetric consequences of intrafraction prostate motionHaisen S Li
Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA
Int J Radiat Oncol Biol Phys 71:801-12. 2008..To analyze characteristics of intrafraction prostate motion, monitored using the Calypso system, and investigate dosimetric consequences of the motion for different clinical target volume (CTV) to planning target volume (PTV) margins...
An arteriovenous malformation model for stereotactic radiosurgery researchReza Jahan
Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA
Neurosurgery 61:152-9; discussion 159. 2007..To introduce the utilization of a swine arteriovenous malformation (AVM) model for stereotactic radiosurgery research and to describe the morphological changes in the vessels after radiation...
Targeting accuracy of an image guided gating system for stereotactic body radiotherapyStephen E Tenn
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Phys Med Biol 50:5443-62. 2005..5 +/- 0.2 mm for phantom rotations up to 5 degrees. We found and corrected a synchronization error caused by a faulty x-ray duration setting and detected a 60 +/- 20 ms time delay in our linear accelerator...
Respiratory correlated cone-beam computed tomography on an isocentric C-armSergey Kriminski
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Phys Med Biol 50:5263-80. 2005..Images reconstructed from the retrospectively gated projection sequences using the optimal gating window data showed a significant improvement compared to images reconstructed from the complete projection datasets...
Intracranial stereotactic positioning systems: Report of the American Association of Physicists in Medicine Radiation Therapy Committee Task Group no. 68A W Lightstone
Department of Medical Physics, Toronto Sunnybrook Regional Cancer Centre, Toronto, Ontario M4N 3M5, Canada
Med Phys 32:2380-98. 2005....
Contrast-enhanced brachytherapy for prostate cancerAmos Norman
Department of Radiation Oncology, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, USA
Acad Radiol 9:S182-4. 2002
Dosimetric parameters for three low-energy brachytherapy sources using the Monte Carlo N-particle codeJohn J DeMarco
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095 6951, USA
Med Phys 29:662-8. 2002..Radial dose function, g(r), calculated to a distance of 10 cm, and an isotropy function, F(r, theta), calculated for radii from 0.5 to 7.0 cm, were found to be in close agreement with previously published data...
An evaluation of gating window size, delivery method, and composite field dosimetry of respiratory-gated IMRTGeoffrey D Hugo
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
Med Phys 29:2517-25. 2002..For multiple field IMRT delivery, the largest errors were generated in regions where high field modulation was present parallel to the axis of motion. Gating was found to reduce these large errors to clinically acceptable levels...
A Monte Carlo based phase space model for quality assurance of intensity modulated radiotherapy incorporating leaf specific characteristicsRandi F Aaronson
Department of Radiation Oncology, University of California, Los Angeles, California 90095 6951, USA
Med Phys 29:2952-8. 2002..53 criteria for all benchmark fields used. Film dosimetry was used to evaluate the model for IMRT sequences and plans, and the ability of the model to account for leaf sequencing effects is also demonstrated...
Patient specific quality assurance for the delivery of intensity modulated radiotherapyNzhde Agazaryan
Department of Radiation Oncology, UCLA School of Medicine, 200 UCLA Medical Plaza, Suite B265, Los Angeles, California 90095 6951, USA
J Appl Clin Med Phys 4:40-50. 2003..Absolute dosimetry for each composite plan is performed using an ionization chamber. To date, excellent agreement between measurements and calculations has been observed...
A seed specific dose kernel method for low-energy brachytherapy dosimetryJohn J DeMarco
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
J Appl Clin Med Phys 4:66-74. 2003..Good agreement is achieved for a representative pre- and post-plan comparison versus a commercial implementation of the TG-43 brachytherapy dosimetry protocol...
Absence of multiple local minima effects in intensity modulated optimization with dose-volume constraintsJorge Llacer
EC Engineering Consultants, LLC 130, Forest Hill Drive, Los Gatos, CA 95032, USA
Phys Med Biol 48:183-210. 2003..The results of the latter two methods have only been discussed briefly, as they yielded the same conclusions as the NG method...
Initial clinical results of stereotactic radiotherapy for the treatment of craniopharyngiomasMichael T Selch
Department of Radiation Oncology, School of Medicine, University of California, Los Angeles CA 90095, USA
Technol Cancer Res Treat 1:51-9. 2002..Further clinical experience is necessary to determine the clinical utility of beam shaping in the setting of SRT...
The effects of tumor motion on planning and delivery of respiratory-gated IMRTGeoffrey D Hugo
Department of Radiation Oncology, UCLA School of Medicine, Los Angeles, California 90095, USA
Med Phys 30:1052-66. 2003..The utilization of gating for IMRT treatment, including imaging, planning, and delivery, significantly reduces the errors introduced by object motion...
Three-dimensional fast imaging employing steady-state acquisition magnetic resonance imaging for stereotactic radiosurgery of trigeminal neuralgiaGabriela del Rocío Chávez Chávez
Division of Neurosurgery, University of California at Los Angeles, Los Angeles, California, USA
Neurosurgery 56:E628; discussion E628. 2005....
Stereotactic radiotherapy for the treatment of acoustic neuromasMichael T Selch
Department of Radiation Oncology and Division of Neurosurgery, David Geffen School of Medicine, University of California, 90045 6951, USA
J Neurosurg 101:362-72. 2004..The authors sought to assess the safety and efficacy of stereotactic radiotherapy when using a linear accelerator equipped with a micromultileaf collimator for the treatment of patients with acoustic neuromas...
A methodology for verification of radiotherapy dose calculationNzhde Agazaryan
Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California 90095 6951, USA
J Neurosurg 101:356-61. 2004..Dosimetric accuracy of clinically active intensity-modulated radiotherapy (IMRT) and intensity-modulated radiosurgery (IMRS) programs was assessed using this methodology...
Degeneracy, frequency response and filtering in IMRT optimizationJorge Llacer
EC Engineering Consultants LLC, 130 Forest Hill Drive, Los Gatos, CA 95032, USA
Phys Med Biol 49:2853-80. 2004..Stopping points for the studied algorithms are discussed and the deterioration of DVH characteristics with filtering is shown to be partially recoverable by the use of space-variant filtering techniques...
Stereotactic radiotherapy for treatment of cavernous sinus meningiomasMichael T Selch
Department of Radiation Oncology, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA 90045 6951, USA
Int J Radiat Oncol Biol Phys 59:101-11. 2004..To assess the safety and efficacy of stereotactic radiotherapy (SRT) using a linear accelerator equipped with a micromultileaf collimator for cavernous sinus meningiomas...
Stereotactic radiotherapy for the treatment of lymphocytic hypophysitis. Report of two casesMichael T Selch
Department of Radiation Oncology, Division of Neurological Surgery, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at the University of California at Los Angeles, California 90095 6951, USA
J Neurosurg 99:591-6. 2003....
Segmental and dynamic intensity-modulated radiotherapy delivery techniques for micro-multileaf collimatorNzhde Agazaryan
Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 6951, USA
Med Phys 30:1758-67. 2003....
Antiproton radiotherapyNiels Bassler
Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark
Radiother Oncol 86:14-9. 2008..This will enable us to perform planning studies, where the potential clinical consequences can be examined, and compared to those of other beam modalities such as protons, carbon ions, or IMRT photons...
Investigations of a minimally invasive method for treatment of spinal malignancies with LINAC stereotactic radiation therapy: accuracy and animal studiesPaul M Medin
Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA
Int J Radiat Oncol Biol Phys 52:1111-22. 2002..Phantom measurements suggest that localization accuracy similar to intracranial stereotactic radiotherapy techniques is achievable. Swine studies suggest that the implant technique is expedient and feasible for tumor targeting purposes...
