Research Topics
| Konstantin SokolovSummaryAffiliation: University of Texas Country: USA Publications
Research Grants
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Detail Information
Publications
Optical spectroscopy for detection of neoplasiaKonstantin Sokolov
Department of Biomedical Engineering, The University of Texas, Austin 78712, USA
Curr Opin Chem Biol 6:651-8. 2002..In the future, improving our understanding of the biological changes that can be assessed using spectroscopy will not only improve optical techniques but also provide new tools to better understand cancer biology...- Polarized reflectance spectroscopy for pre-cancer detectionKonstantin Sokolov
Department of Imaging Physics, M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 56, Houston, TX 77030, USA
Technol Cancer Res Treat 3:1-14. 2004..We gradually progress from cell suspensions to realistic three-dimensional tissue models of epithelium, then to cervical biopsies and, finally to in vivo studies on normal volunteers and clinical patients... 
Cancer imaging and therapy with metal nanoparticlesKonstantin Sokolov
Department of Imaging Physics, The UT M D Anderson Cancer Center, Houston, TX 77030, USA
Conf Proc IEEE Eng Med Biol Soc 2009:2005-7. 2009..Here, we will present a case study of plasmonic nanoparticles in cancer imaging and therapy...
Multiwavelength photoacoustic imaging and plasmon resonance coupling of gold nanoparticles for selective detection of cancerSrivalleesha Mallidi
Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas 78712, USA
Nano Lett 9:2825-31. 2009..The results of our study suggest that highly selective and sensitive detection of cancer cells is possible using multiwavelength photoacoustic imaging and molecular specific gold nanoparticles...- Enhanced thermal stability of silica-coated gold nanorods for photoacoustic imaging and image-guided therapyYun Sheng Chen
Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, 78712, USA
Opt Express 18:8867-78. 2010.... - Molecular therapeutic agents for noninvasive photoacoustic image-guided photothermal therapyPratixa P Joshi
Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA
Conf Proc IEEE Eng Med Biol Soc 2009:4106-9. 2009.... - On sensitivity of molecular specific photoacoustic imaging using plasmonic gold nanoparticlesSrivalleesha Mallidi
Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA
Conf Proc IEEE Eng Med Biol Soc 2009:6338-40. 2009..The results of our study indicate that highly sensitive detection of cancer cells is feasible using photoacoustic imaging and plasmonic gold nanoparticles... - Plasmon resonance coupling of metal nanoparticles for molecular imaging of carcinogenesis in vivoJesse Aaron
University of Texas at Austin, Department of Biomedical Engineering, Austin, Texas 78712, USA
J Biomed Opt 12:034007. 2007.... - Photoacoustic imaging and temperature measurement for photothermal cancer therapyJignesh Shah
University of Texas at Austin, Department of Biomedical Engineering, Austin, Texas 78712, USA
J Biomed Opt 13:034024. 2008..The results of our study suggest that photoacoustic imaging, augmented by ultrasound imaging, is a viable candidate to guide photoabsorber-enhanced photothermal therapy... - Optical imaging of cervical pre-cancers with structured illumination: an integrated approachMohammed Rahman
Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA
Gynecol Oncol 99:S112-5. 2005..Combining structured illumination microscopy with novel contrast agents can potentially provide a powerful and inexpensive tool to aid in the detection of cervical pre-cancers... - Real-time vital optical imaging of precancer using anti-epidermal growth factor receptor antibodies conjugated to gold nanoparticlesKonstantin Sokolov
Department of Imaging Physics, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA
Cancer Res 63:1999-2004. 2003..They can potentially enable combined screening, detection, and therapy of disease using inexpensive imaging systems; such tools could allow mass screening of diseases such as cancer in resource-poor settings... - Multispectral optical imaging device for in vivo detection of oral neoplasiaDarren Roblyer
Rice University, Department of Bioengineering, 6100 Main St, Houston, Texas 77251 1892, USA
J Biomed Opt 13:024019. 2008.... - Molecular optical imaging of therapeutic targets of cancerKonstantin Sokolov
Department of Imaging Physics, MD Anderson Cancer Center, Houston, Texas 77030, USA
Adv Cancer Res 96:299-344. 2007.... - Intravascular ultrasound and photoacoustic imagingSTANISLAV EMELIANOV
Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA
Conf Proc IEEE Eng Med Biol Soc 2008:2-5. 2008..Finally, molecular and cellular IVPA imaging was demonstrated using plasmonic nanoparticles. Overall, our studies suggest that plaque detection and characterization can be improved using the combined IVPA/IVUS imaging... - Microanatomical and biochemical origins of normal and precancerous cervical autofluorescence using laser-scanning fluorescence confocal microscopyIna Pavlova
Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX, USA
Photochem Photobiol 77:550-5. 2003..These changes can explain differences in in vivo fluorescence spectra of normal and precancerous cervical tissue... - Dynamic imaging of molecular assemblies in live cells based on nanoparticle plasmon resonance couplingJesse Aaron
Department of Biomedical Engineering, Department of Physics, University of Texas at Austin, Austin, Texas 78712, USA
Nano Lett 9:3612-8. 2009.... - Plasmonic intravascular photoacoustic imaging for detection of macrophages in atherosclerotic plaquesBo Wang
Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas 78712, USA
Nano Lett 9:2212-7. 2009.... - Preventing protein adsorption and macrophage uptake of gold nanoparticles via a hydrophobic shieldTimothy A Larson
Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas 78712, USA
ACS Nano 6:9182-90. 2012..The mPEG-alkyl-thiol coating greatly reduces protein adsorption on GNPs and their macrophage uptake. This has important implications for the design of GNP for biological systems... - Compact beveled fiber optic probe design for enhanced depth discrimination in epithelial tissuesLinda T Nieman
Department of Biomedical Engineering, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Austin, TX 77030, USA
Opt Express 17:2780-96. 2009.... - Adaptive spectral window sizes for extraction of diagnostic features from optical spectraChih Wen Kan
The University of Texas, Department of Biomedical Engineering, Austin, Texas 78712 1084, USA
J Biomed Opt 15:047012. 2010..Because adaptive windows retain most diagnostic information while reducing the number of windows needed for feature extraction, our results suggest that it isolates unique diagnostic features in optical spectra... - Two-photon luminescence imaging of cancer cells using molecularly targeted gold nanorodsNicholas J Durr
Department of Biomedical Engineering, The University of Texas at Austin, Austin, Texas 78712, USA
Nano Lett 7:941-5. 2007.... - Probing local tissue changes in the oral cavity for early detection of cancer using oblique polarized reflectance spectroscopy: a pilot clinical trialLinda T Nieman
The University of Texas M D Anderson Cancer Center, Department of Biomedical Engineering, 1515 Holcombe Boulevard, Houston, Texas 77030, USA
J Biomed Opt 13:024011. 2008..These promising results suggest that OPRS has the potential to aid screening and diagnosis of oral precancer and cancer... - Endoscopic microscopyKonstantin Sokolov
Department of Imaging Physics, UT M.D. Anderson Cancer Center, Houston, TX 77030, USA
Dis Markers 18:269-91. 2002..In conclusion, we discuss future improvements to the technology needed to develop robust clinical devices... - Combined photoacoustic and magneto-acoustic imagingMin Qu
Ultrasound Imaging and Therapeutics Research Laboratory in the Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712 0238, USA
Conf Proc IEEE Eng Med Biol Soc 2009:4763-6. 2009..Therefore, the developed imaging technique can be used in wide range of biomedical and clinical application... - Function of mesenchymal stem cells following loading of gold nanotracersLaura M Ricles
Department of Biomedical Engineering, The University of Texas at Austin, 1 University Station, Austin, TX, USA
Int J Nanomedicine 6:407-16. 2011..The objective of the current study was to assess the effects of loading MSCs with gold nanoparticles on cellular function... - Ultrasound imaging to monitor photothermal therapy - feasibility studyJignesh Shah
Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA
Opt Express 16:3776-85. 2008..The results of our study suggest that ultrasound imaging is a candidate approach to remotely guide photothermal therapy... - Plasmonic nanosensors for imaging intracellular biomarkers in live cellsSonia Kumar
Department of Biomedical Engineering, University of Texas at Austin, Austin, Texas 78712, USA
Nano Lett 7:1338-43. 2007..These multifunctional nanosensors can be adapted to target various intracellular processes especially where transfection or cytotoxic labels are not feasible... - A far-red fluorescent contrast agent to image epidermal growth factor receptor expressionElizabeth R Hsu
Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA
Photochem Photobiol 79:272-9. 2004..This contrast agent should have important clinical applications for use in conjunction with fluorescence spectroscopy or imaging (or both) to facilitate tumor detection and demarcation...
Research Grants
- Polarization Spectroscopy and Imaging of Pre-CancerKonstantin Sokolov; Fiscal Year: 2007..The inexpensive optical sensors proposed here can immediately benefit health care by reducing the number of unnecessary biopsies, enabling combined diagnosis and therapy, and reducing the need for clinical expertise. ..
- Biodegradable Plasmonic Nanoparticles for Cancer Imaging and TherapyKonstantin V Sokolov; Fiscal Year: 2010....