Jonathan P Sokol
Affiliation: University of Wisconsin-Madison
- The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-betaJonathan P Sokol
Program in Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO, USA
Breast Cancer Res 7:R844-53. 2005..We hypothesized that the oncogenic activities of TGF-beta, particularly its stimulation of mammary epithelial-mesenchymal transition (EMT), can be prevented by CystC...
- Cystatin C antagonizes transforming growth factor beta signaling in normal and cancer cellsJonathan P Sokol
Program in Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA
Mol Cancer Res 2:183-95. 2004..Collectively, our findings have identified CystC as a novel TGF-beta receptor antagonist, as well as a novel CystC-mediated feedback loop that inhibits TGF-beta signaling...