Donald L Sodora

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus
    Donald L Sodora
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9113, USA
    J Virol 76:9981-90. 2002
  2. ncbi Timely triggering of homeostatic mechanisms involved in the regulation of T-cell levels in SIVsm-infected sooty mangabeys
    Alagarraju Muthukumar
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9113, USA
    Blood 106:3839-45. 2005
  3. ncbi Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host
    Jeffrey M Milush
    University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    J Immunol 179:3047-56. 2007
  4. ncbi Rapid dissemination of SIV following oral inoculation
    Jeffrey M Milush
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9113, USA
    AIDS 18:2371-80. 2004
  5. ncbi Mucosal innate immune response associated with a timely humoral immune response and slower disease progression after oral transmission of simian immunodeficiency virus to rhesus macaques
    Jeffrey M Milush
    Department of Internal Medicine, University of Texas, Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9113, USA
    J Virol 81:6175-86. 2007
  6. ncbi Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells
    Jeffrey M Milush
    Division of Infectious Disease, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Clin Invest 121:1102-10. 2011
  7. ncbi Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus-induced disease progression
    Alagarraju Muthukumar
    University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Blood 103:973-9. 2004
  8. ncbi In vivo analysis of Nef function
    Bangdong L Wei
    Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9113, USA
    Curr HIV Res 1:41-50. 2003
  9. ncbi HIV and CXCR4 in a kiss of autophagic death
    Beth Levine
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9113, USA
    J Clin Invest 116:2078-80. 2006
  10. ncbi Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors
    Loyda Ylisastigui
    University of Texas Southwestern Medical Center at Dallas, Department of Medicine, Division of Infectious Diseases, Dallas, Texas 75390-9113, USA
    J Infect Dis 190:1429-37. 2004

Research Grants

  1. Viral Cytopathicity in CD4-Low SIV Passaged Mangabeys
    Dolores Peterson; Fiscal Year: 2006

Collaborators

Detail Information

Publications10

  1. ncbi Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus
    Donald L Sodora
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9113, USA
    J Virol 76:9981-90. 2002
    ..SIV infection of macaques will be a useful model system to elucidate the mechanisms responsible for the thymic dysfunction observed in HIV-infected patients...
  2. ncbi Timely triggering of homeostatic mechanisms involved in the regulation of T-cell levels in SIVsm-infected sooty mangabeys
    Alagarraju Muthukumar
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9113, USA
    Blood 106:3839-45. 2005
    ....
  3. ncbi Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host
    Jeffrey M Milush
    University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    J Immunol 179:3047-56. 2007
    ....
  4. ncbi Rapid dissemination of SIV following oral inoculation
    Jeffrey M Milush
    Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9113, USA
    AIDS 18:2371-80. 2004
    ..The rapidity with which SIV, and probably HIV, spreads throughout the lymphatics indicates a major obstacle for a vaccine amnestic immune response to eliminate infected cells prior to dissemination...
  5. ncbi Mucosal innate immune response associated with a timely humoral immune response and slower disease progression after oral transmission of simian immunodeficiency virus to rhesus macaques
    Jeffrey M Milush
    Department of Internal Medicine, University of Texas, Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9113, USA
    J Virol 81:6175-86. 2007
    ....
  6. ncbi Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells
    Jeffrey M Milush
    Division of Infectious Disease, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Clin Invest 121:1102-10. 2011
    ....
  7. ncbi Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus-induced disease progression
    Alagarraju Muthukumar
    University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Blood 103:973-9. 2004
    ..The utility of IL-7 as a potential immunotherapeutic agent to improve HIV/SIV-related T-cell depletion may therefore depend on controlling the pathogenic effects of viral replication prior to the administration of IL-7...
  8. ncbi In vivo analysis of Nef function
    Bangdong L Wei
    Department of Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9113, USA
    Curr HIV Res 1:41-50. 2003
    ..The knowledge that has been accumulated has provided clues to our understanding of Nef function but they have also left us with many unanswered questions that should be the focus of future in vivo analysis of Nef function...
  9. ncbi HIV and CXCR4 in a kiss of autophagic death
    Beth Levine
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9113, USA
    J Clin Invest 116:2078-80. 2006
    ..The HIV envelope glycoprotein interacts with CXC chemokine receptor 4 to activate the lysosomal degradation pathway of autophagy, which is necessary for both apoptotic and nonapoptotic cell death...
  10. ncbi Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors
    Loyda Ylisastigui
    University of Texas Southwestern Medical Center at Dallas, Department of Medicine, Division of Infectious Diseases, Dallas, Texas 75390-9113, USA
    J Infect Dis 190:1429-37. 2004
    ..CONCLUSIONS: We identify histone deacetylation as a mechanism that can dampen viral expression in infected, activated CD4+ T cells and establish a persistent, quiescent reservoir of HIV infection...

Research Grants1

  1. Viral Cytopathicity in CD4-Low SIV Passaged Mangabeys
    Dolores Peterson; Fiscal Year: 2006
    ..abstract_text> ..