Research Topics
Species | Beth E SnitzSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Identifying mild cognitive impairment at baseline in the Ginkgo Evaluation of Memory (GEM) studyBeth E Snitz
Department of Neurology, University of Pittsburgh
Aging Ment Health 13:171-82. 2009..To identify, characterize and compare the frequency of mild cognitive impairment (MCI) subtypes at baseline in a large, late-life cohort (n = 3063) recruited into a dementia prevention trial...
Subjective cognitive complaints of older adults at the population level: an item response theory analysisBeth E Snitz
Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA
Alzheimer Dis Assoc Disord 26:344-51. 2012..Modern psychometric approaches including IRT may be useful in developing: (1) brief community screening questionnaires; and (2) more sensitive measures of very subtle subjective decline for use in prodromal Alzheimer disease research...
Effects of age, gender, education and race on two tests of language ability in community-based older adultsBeth E Snitz
Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Int Psychogeriatr 21:1051-62. 2009..We report population-based normative data on these tests from two combined ethnically divergent, cognitively normal, representative population samples of older adults...
A novel approach to assessing memory at the population level: vulnerability to semantic interferenceBeth E Snitz
Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Int Psychogeriatr 22:785-94. 2010..It is not yet known how broadly this work will generalize to the community at large...
Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypesBeth E Snitz
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Schizophr Bull 32:179-94. 2006..Cognitive deficits, particularly those tapping such executive control functions, should continue to prove valuable as endophenotypes of interest in the search for specific genetic factors related to schizophrenia...
Subjective memory complaints and concurrent memory performance in older patients of primary care providersBeth E Snitz
Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Int Neuropsychol Soc 14:1004-13. 2008....
Outcomes of mild cognitive impairment by definition: a population studyMary Ganguli
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Arch Neurol 68:761-7. 2011..Mild cognitive impairment (MCI) has been defined in several ways...
Cognitive test performance predicts change in functional status at the population level: the MYHAT ProjectMary Ganguli
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
J Int Neuropsychol Soc 16:761-70. 2010..At the population level, changes in both directions are observable in functional status, with different neuropsychological measures predicting the direction of change...
Ginkgo biloba for preventing cognitive decline in older adults: a randomized trialBeth E Snitz
Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
JAMA 302:2663-70. 2009..The herbal product Ginkgo biloba is taken frequently with the intention of improving cognitive health in aging. However, evidence from adequately powered clinical trials is lacking regarding its effect on long-term cognitive functioning...
Frequent amyloid deposition without significant cognitive impairment among the elderlyHoward Jay Aizenstein
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Arch Neurol 65:1509-17. 2008....
Prevalence of mild cognitive impairment by multiple classifications: The Monongahela-Youghiogheny Healthy Aging Team (MYHAT) projectMary Ganguli
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
Am J Geriatr Psychiatry 18:674-83. 2010..To estimate and compare the frequency and prevalence of mild cognitive impairment (MCI) and related entities using different classification approaches at the population level...
Amyloid imaging in dementias with atypical presentationDavid A Wolk
Department of Neurology, University of Pennsylvania, Philadelphia, USA
Alzheimers Dement 8:389-98. 2012..We explored the potential value of amyloid imaging in patients with atypical presentations of dementia...
Age and education effects and norms on a cognitive test battery from a population-based cohort: the Monongahela-Youghiogheny Healthy Aging TeamMary Ganguli
Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Aging Ment Health 14:100-7. 2010..Performance on cognitive tests can be affected by age, education, and also selection bias. We examined the distribution of scores on several cognitive screening tests by age and educational levels in a population-based cohort...
Basal cerebral metabolism may modulate the cognitive effects of Abeta in mild cognitive impairment: an example of brain reserveAnn D Cohen
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
J Neurosci 29:14770-8. 2009....
Mild cognitive deficits and everyday functioning among older adults in the community: the Monongahela-Youghiogheny Healthy Aging Team studyTiffany F Hughes
Department of Psychiatry, School of Medicine, and the Departments of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Geriatr Psychiatry 20:836-44. 2012..We examined the ability to perform multiple IADL tasks in relation to mild cognitive impairment (MCI) defined on purely neuropsychological grounds...
Patterns of mild cognitive impairment after treatment of depression in the elderlyRishi K Bhalla
Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Am J Geriatr Psychiatry 17:308-16. 2009....
Cognitive trajectories associated with β-amyloid deposition in the oldest-old without dementiaBeth E Snitz
From the Departments of Neurology B E S, O L L, J S, E M, Biostatistics L A W, D M S, Epidemiology L H K, D G I, Psychiatry W E K, A D C, and Radiology C A M, J C P, University of Pittsburgh, Pittsburgh, PA and School of Medicine S T D, University of Virginia, Charlottesville
Neurology 80:1378-84. 2013..To determine whether a high prevalence (55%) of Aβ deposition in a cohort of individuals remaining dementia-free into their 9th and 10th decades is associated with cognitive decline prior to imaging...
Should mild cognitive impairment be subtyped?Tiffany F Hughes
Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Curr Opin Psychiatry 24:237-42. 2011..To review evidence on the validity and utility of recent approaches to subtyping late-life mild cognitive impairment...
Cross-validation of brain structural biomarkers and cognitive aging in a community-based studyJames T Becker
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Int Psychogeriatr 24:1065-75. 2012..We examined the feasibility of acquiring state-of-the-art brain MRI images at a community hospital, and attempted to cross-validate two independent approaches to image analysis...
High medical co-morbidity and family history of dementia is associated with lower cognitive function in older patientsLisa A Morrow
Department of Psychiatry, University of Pittsburgh, PA, USA
Fam Pract 26:339-43. 2009..Risk factors for cognitive decline in ageing are multifactorial, including medical co-morbidities and familial genetic risk...
Ginkgo biloba for prevention of dementia: a randomized controlled trialSteven T DeKosky
University of Pittsburgh, Pittsburgh, Pennsylvania, USA
JAMA 300:2253-62. 2008..Ginkgo biloba is widely used for its potential effects on memory and cognition. To date, adequately powered clinical trials testing the effect of G. biloba on dementia incidence are lacking...
Amyloid imaging in mild cognitive impairment subtypesDavid A Wolk
Alzheimer s Disease Research Center, University of Pittsburgh, Pittsburgh, PA 19104, USA
Ann Neurol 65:557-68. 2009....
Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigreesWilliam E Klunk
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
J Neurosci 27:6174-84. 2007..The early, focal striatal amyloid deposition observed in these PS1 mutation carriers is often is not associated with clinical symptoms...
Lateral and medial hypofrontality in first-episode schizophrenia: functional activity in a medication-naive state and effects of short-term atypical antipsychotic treatmentBeth E Snitz
Department of Psychiatry, University of Pittsburgh Medical School, USA
Am J Psychiatry 162:2322-9. 2005..These findings are consistent with an emerging literature documenting short-term benefits of atypical antipsychotic medication for the neural circuitry underlying cognitive deficits in schizophrenia...
Automated ROI-based brain parcellation analysis of frontal and temporal brain volumes in schizophreniaPilar Lopez-Garcia
Department of Psychiatry, School of Medicine, University of California, Davis, United States
Psychiatry Res 147:153-61. 2006..The automated ROI-based method can be used as a valid and efficient tool for quantification of regional gray matter volume in schizophrenia in multiple ROIs across the brains of large numbers of subjects...
Remote memory in advanced Alzheimer's diseaseGiuseppe Sartori
Dipartimento di Psicologia Generale, Universita di Padova, Via Venezia 8, 35100 Padova, Italy
Arch Clin Neuropsychol 19:779-89. 2004..Overall, results indicate a minimal outline of preserved remote memory in advanced DAT, with evidence of an association between remote memory performance and executive functioning...
Impaired processing of affective prosody in Korsakoff's syndromeBeth E Snitz
Faculty of Psychology, AE Neuropsychology, Ruhr-University of Bochum, Germany
Cortex 38:797-803. 2002..These results suggest that Korsakoff patients are impaired in interpreting the meaning of affective prosody in the absence of semantic cues as to the emotional content of sentences...
