Shikha Snigdha

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California Irvine, CA, USA
    Neurobiol Aging 34:1891-901. 2013
  2. pmc Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain
    S Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA, USA
    Neuroscience 202:326-33. 2012
  3. pmc Phencyclidine (PCP)-induced disruption in cognitive performance is gender-specific and associated with a reduction in brain-derived neurotrophic factor (BDNF) in specific regions of the female rat brain
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697 4540, USA
    J Mol Neurosci 43:337-45. 2011
  4. pmc Age and distraction are determinants of performance on a novel visual search task in aged Beagle dogs
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, 1226 Gillespie NRF, Irvine, CA 92697 4540, USA
    Age (Dordr) 34:67-73. 2012
  5. pmc Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 6:e24652. 2011
  6. pmc Caspase-3 activation as a bifurcation point between plasticity and cell death
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, California 92697 4540, USA
    Neurosci Bull 28:14-24. 2012
  7. doi request reprint Asenapine improves phencyclidine-induced object recognition deficits in the rat: evidence for engagement of a dopamine D1 receptor mechanism
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697 4540, USA
    Psychopharmacology (Berl) 214:843-53. 2011

Detail Information

Publications8

  1. pmc A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California Irvine, CA, USA
    Neurobiol Aging 34:1891-901. 2013
    ..We also suggest areas in which new tests may benefit the development of a comprehensive preclinical test battery for assessment of cognitive function in animal models of aging and Alzheimer's disease...
  2. pmc Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain
    S Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, CA, USA
    Neuroscience 202:326-33. 2012
    ..Together with data showing increased palmitoleic acid levels in AD patients, our data suggest that reducing palmitoleic acid levels and desaturation index in the brain may be associated with improved cognitive performance...
  3. pmc Phencyclidine (PCP)-induced disruption in cognitive performance is gender-specific and associated with a reduction in brain-derived neurotrophic factor (BDNF) in specific regions of the female rat brain
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA 92697 4540, USA
    J Mol Neurosci 43:337-45. 2011
    ....
  4. pmc Age and distraction are determinants of performance on a novel visual search task in aged Beagle dogs
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, 1226 Gillespie NRF, Irvine, CA 92697 4540, USA
    Age (Dordr) 34:67-73. 2012
    ..This is likely to be derived from impairments in cognitive domains such as visual memory and learning and selective attention...
  5. pmc Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 6:e24652. 2011
    ....
  6. pmc Caspase-3 activation as a bifurcation point between plasticity and cell death
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, California 92697 4540, USA
    Neurosci Bull 28:14-24. 2012
    ..Specifically, we propose that limited caspase-3 activation is critical for synaptic function in the healthy adult brain while chronic activation is involved in degenerative processes in the aging brain...
  7. doi request reprint Asenapine improves phencyclidine-induced object recognition deficits in the rat: evidence for engagement of a dopamine D1 receptor mechanism
    Shikha Snigdha
    Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, 92697 4540, USA
    Psychopharmacology (Berl) 214:843-53. 2011
    ....