Research Topics
| P K SneedSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
A multi-institutional review of radiosurgery alone vs. radiosurgery with whole brain radiotherapy as the initial management of brain metastasesPenny K Sneed
Department of Radiation Oncology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0226, USA
Int J Radiat Oncol Biol Phys 53:519-26. 2002..Data collected from 10 institutions were reviewed to compare survival probabilities of patients with newly diagnosed brain metastases managed initially with radiosurgery (RS) alone vs. RS + whole brain radiotherapy (WBRT)...
Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiformeP K Sneed
Department of Radiation Oncology, University of California, San Francisco 94143 0226, USA
Int J Radiat Oncol Biol Phys 40:287-95. 1998..To determine if adjuvant interstitial hyperthermia (HT) significantly improves survival of patients with glioblastoma undergoing brachytherapy boost after conventional radiotherapy...
EGFR overexpression and radiation response in glioblastoma multiformeF G Barker
Department of Neurological Surgery, Neuro Oncology Service and Brain Tumor Research Center, University of California, San Francisco, California, USA
Int J Radiat Oncol Biol Phys 51:410-8. 2001..We tested whether these abnormalities correlated with clinical heterogeneity in GM response to radiation treatment...
Phase III trial of accelerated hyperfractionation with or without difluromethylornithine (DFMO) versus standard fractionated radiotherapy with or without DFMO for newly diagnosed patients with glioblastoma multiformeM D Prados
Department of Neurosurgery, University of California San Francisco, San Francisco, CA 94143 0372, USA
Int J Radiat Oncol Biol Phys 49:71-7. 2001....
Interstitial brachytherapy for malignant brain tumorsM W McDermott
Department of Neurological Surgery, University of California, San Francisco 94143 0350, USA
Semin Surg Oncol 14:79-87. 1998..In spite of the increased availability of radiosurgery, interstitial brachytherapy still has a place in the management of these difficult tumors...
Age and radiation response in glioblastoma multiformeF G Barker
Neuro Oncology Service, Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, San Francisco, USA
Neurosurgery 49:1288-97; discussion 1297-8. 2001..Radiographically assessed tumor response to external beam radiation therapy is an important prognostic factor in GM. We hypothesized that older GM patients might have more radioresistant tumors...
Radiosurgery for brain metastases from primary lung carcinomaR Hoffman
Department of Radiation Oncology, University of California, San Francisco 94143-0226, USA
Cancer J 7:121-31. 2001..Prospective, randomized trials are needed to further investigate the role of radiosurgery with and without whole-brain radiotherapy for brain metastases...
Volume MRI and MRSI techniques for the quantitation of treatment response in brain tumors: presentation of a detailed case studyS J Nelson
Department of Radiology, University of California, San Francisco 94143, USA
J Magn Reson Imaging 7:1146-52. 1997....
The role of radiation therapy in the treatment of craniopharyngiomaW M Wara
Department of Radiation Oncology, University of California, San Francisco 94143
Pediatr Neurosurg 21:98-100. 1994..Patients undergoing a complete resection may be observed for subsequent recurrence. If a subtotal resection or biopsy is obtained, that patient should be irradiated with modern techniques to a dose of 5,400 cGy at 180 cGy/fraction...
Distinguishing recurrent intra-axial metastatic tumor from radiation necrosis following gamma knife radiosurgery using dynamic susceptibility-weighted contrast-enhanced perfusion MR imagingR F Barajas
Department of Radiology, Neuroradiology Section University of California, San Francisco, San Francisco, CA 94143, USA
AJNR Am J Neuroradiol 30:367-72. 2009....
A two-step optimization method for improving multiple brain lesion treatments with robotic radiosurgeryL Ma
University of California San Francisco, Department of Radiation Oncology and Neurosurgery, UCSF Medical Center 505 Parnassus Avenue, Room L08 San Francisco, CA 94143, USA
Technol Cancer Res Treat 10:331-8. 2011..In summary, a two-step optimization technique is demonstrated to significantly improve the treatment plan quality as well as reduce the planning effort for multi-target robotic radiosurgery...
Dose conformity of gamma knife radiosurgery and risk factors for complicationsJ L Nakamura
Department of Radiation Oncology, University of California, San Francisco, CA 94143-0226, USA
Int J Radiat Oncol Biol Phys 51:1313-9. 2001..Larger target, nontarget, or prescription volumes are associated with increased risk of toxicity...
MR-spectroscopy guided target delineation for high-grade gliomasA Pirzkall
Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA 94143 0226, USA
Int J Radiat Oncol Biol Phys 50:915-28. 2001..We assessed the impact MRSI might have on the target volumes used for radiation therapy treatment planning for high-grade gliomas...
Stereotactic radiosurgery and interstitial brachytherapy for glial neoplasmsM W McDermott
Department of Neurosurgery, University of California, San Francisco, CA, USA
J Neurooncol 69:83-100. 2004..This paper reviews the recent literature and results of the use of brachytherapy and radiosurgery in the management of newly diagnosed and recurrent malignant gliomas...
Metabolic imaging of low-grade gliomas with three-dimensional magnetic resonance spectroscopyAndrea Pirzkall
Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA 94143, USA
Int J Radiat Oncol Biol Phys 53:1254-64. 2002..We performed a study examining the impact MRSI would have on the routine addition of 2-3-cm margins around MRI T2-weighted hyperintensity to generate the treatment planning clinical target volume (CTV) for low-grade gliomas...
Brain metastases in breast cancer: clinical and pathologic characteristics associated with improvements in survivalMichelle E Melisko
Department of Medicine, University of California San Francisco, 1600 Divisadero Street, San Francisco, CA 94115, USA
J Neurooncol 88:359-65. 2008..As breast cancer patients live longer with control of systemic disease, survival after the diagnosis of brain metastases (BM) also appears to be improving...
Management of newly diagnosed single brain metastasis using resection and permanent iodine-125 seeds without initial whole-brain radiotherapy: a two institution experienceElias Dagnew
Department of Neurosurgery, The Neuroscience Institute, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Neurosurg Focus 22:E3. 2007..The authors evaluated the efficacy of resection and placement of 125I seeds (without concomitant WBRT) for newly diagnosed single brain metastases...
Phase I trial of gross total resection, permanent iodine-125 brachytherapy, and hyperfractionated radiotherapy for newly diagnosed glioblastoma multiformeAllen M Chen
Department of Radiation Oncology, University of California, San Francisco School of Medicine, San Francisco, CA 94143 0226, USA
Int J Radiat Oncol Biol Phys 69:825-30. 2007..To evaluate the feasibility of gross total resection and permanent I-125 brachytherapy followed by hyperfractionated radiotherapy for patients with newly diagnosed glioblastoma...
Treatment for posterior fossa dissemination of primary supratentorial gliomaJustin S Smith
Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco, California 94143 0350, USA
J Neurosurg 106:567-74. 2007..This study was designed to assess the presentation, management, and outcome of cases involving patients who had a supratentorial glioma that subsequently progressed in the posterior fossa (PF)...
Prognostic value of detecting recurrent glioblastoma multiforme in surgical specimens from patients after radiotherapy: should pathology evaluation alter treatment decisions?Tarik Tihan
Department of Pathology, University of California at San Francisco, San Francisco, CA 94143 0511, USA
Hum Pathol 37:272-82. 2006..A comprehensive prospective study with advanced radiologic, pathologic, and molecular analyses may be more useful to determine prognostically valuable parameters...
Comparison of intensity-modulated radiosurgery with gamma knife radiosurgery for challenging skull base lesionsJean L Nakamura
Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA 94143, USA
Int J Radiat Oncol Biol Phys 55:99-109. 2003....
Radiosurgery in metastatic brain cancerMichael W McDermott
Department of Neurosurgery, University of California, San Francisco, San Francisco, California 94143, USA
Neurosurgery 57:S45-53; discusssion S1-4. 2005....
Permanent iodine 125 brachytherapy in patients with progressive or recurrent glioblastoma multiformeDavid A Larson
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94143, USA
Neuro Oncol 6:119-26. 2004..We conclude that permanent 125I brachytherapy for recurrent or progressive GM is well tolerated. Survival time was comparable to that of a similar group of patients treated with temporary brachytherapy...
Surgical resection and permanent brachytherapy for recurrent atypical and malignant meningiomaMarcus L Ware
Department of Neurological Surgery and Radiation Oncology, University of California, San Francisco, San Francisco, California 94143, USA
Neurosurgery 54:55-63; discussion 63-4. 2004..The addition of brachytherapy at the time of operation is an option. Here, we report the results of our series of patients with recurrent malignant meningioma treated with resection and brachytherapy with permanent low-dose (125)I...
Gamma knife radiosurgery for recurrent salivary gland malignancies involving the base of skullNancy Lee
Department of Radiation Oncology, University of California San Francisco, 505 Parnassus Ave, L 08 Box 0226, San Francisco, California 94143 0226, USA
Head Neck 25:210-6. 2003..The management of skull base recurrence of salivary gland tumors is challenging, because complete surgical resection and fractionated reirradiation are seldom possible. Experience is being gained with radiosurgery for this indication...
Phase II study of high central dose Gamma Knife radiosurgery and marimastat in patients with recurrent malignant gliomaDavid A Larson
Department of Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, CA 94143 0226, USA
Int J Radiat Oncol Biol Phys 54:1397-404. 2002..To assess the outcome of high central dose Gamma Knife radiosurgery plus marimastat in patients with recurrent malignant glioma...
Stereotactic radiosurgery for pediatric intracranial arteriovenous malformations: the University of California at San Francisco experienceMatthew D Smyth
Department of Neurological Surgery, University of California at San Francisco, 94143 0112, USA
J Neurosurg 97:48-55. 2002..In this study the authors describe a series of pediatric patients with a minimum follow-up duration of 36 months...
Gamma knife radiosurgery for brainstem metastases: the UCSF experienceNorbert Kased
Department of Radiation Oncology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0226, USA
J Neurooncol 86:195-205. 2008..To assess clinical and imaging outcomes in patients treated with Gamma Knife stereotactic radiosurgery (SRS) for brainstem metastases...
Efaproxiral: should we hold our breath?Penny K Sneed
J Clin Oncol 24:13-5. 2006
