Research Topics
| J R SmythiesSummaryAffiliation: University of California Country: USA Publications
| Collaborators |
Detail Information
Publications
Philosophy, perception, and neuroscienceJohn Smythies
Center for Brain and Cognition, University of California San Diego, La Jolla, CA 92093, USA
Perception 38:638-51. 2009..It is directly relevant to criticisms by certain analytical philosophers of aspects of neuroscience relating to these matters. Particular attention is paid to their support for Naive Realism...
Oxidative reactions and schizophrenia: a review-discussionJ R Smythies
Department of Neuropsychiatry, Institute of Neurology, London, UK
Schizophr Res 24:357-64. 1997....
How the brain decides what we seeJohn Smythies
Center for Brain and Cognition, UCSD, La Jolla, CA 92037-0109, USA
J R Soc Med 98:18-20. 2005
Nerve gas antidotesJohn Smythies
Center for Brain and Cognition, UCSD, La Jolla, CA 92093-0109, USA
J R Soc Med 97:32. 2004
Redox aspects of signaling by catecholamines and their metabolitesJ Smythies
Center for Brain and Cognition, Department of Psychology, University of California San Diego, La Jolla 92093 0109, USA
Antioxid Redox Signal 2:575-83. 2000..This might contribute under certain circumstances to synaptic deletion. Evidence is presented that abnormalities in this system may contribute to the pathogenesis of Parkinson's disease and schizophrenia...
What is the function of receptor and membrane endocytosis at the postsynaptic neuron?J Smythies
Center for Brain and Cognition, Department of Psychology, University of California, San Diego, La Jolla 92093 0109, USA
Proc Biol Sci 267:1363-7. 2000..The possible involvement of this system in Alzheimer's disease is discussed...
The neurochemical basis of learning and neurocomputation: the redox theoryJ Smythies
Department of Neuropsychiatry, Institute of Neurology, London, UK
Behav Brain Res 99:1-6. 1999..Mediation of signals of reinforcing stimuli by the catecholamines may be mediated in part by their antioxidant effect on glutamate synapses. Some experiments to test the theory are suggested...
Redox mechanisms at the glutamate synapse and their significance: a reviewJ Smythies
Institute of Neurology, London, UK
Eur J Pharmacol 370:1-7. 1999..Additional agents participating in spine pruning may be neurotoxic catecholamine o-quinones present in the brain. This system may be at fault in schizophrenia and Parkinson's disease. Experiments to test the hypothesis are suggested...
The functional neuroanatomy of awareness: with a focus on the role of various anatomical systems in the control of intermodal attentionJ Smythies
Department of Neuropsychiatry, Institute of Neurology, London, England
Conscious Cogn 6:455-81. 1997..Clinical loss of consciousness results from damage to these nuclei but not from damage to the cholinergic nucleus basalis of the basal forebrain...
Does the O'Brien cycle occur in vivo as a key component in H(2)O(2) production and redox signalling?John Smythies
Center for Brain and Cognition, UCSD, 9500 Gilman Drive, La Jolla, CA 92093 0109, USA
Med Hypotheses 76:299-301. 2011..Three different microanatomical loci are evaluated to explain how the coma might result from these redox reactions...
The oxidative metabolism of catecholamines in the brain: a reviewJ Smythies
Institute of Neurology, Queen Square, London WC1 3BG, UK
Biochim Biophys Acta 1380:159-62. 1998..Supportive evidence is presented from a number of sources including enzymology. A suggestion as to the possible normal function of this system is made...
