Elaine M Smolock

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Identification of a genetic locus on chromosome 11 that regulates leukocyte infiltration in mouse carotid artery
    Elaine M Smolock
    University of Rochester, Aab Cardiovascular Research Institute, 601 Elmwood Ave, Box CVRI, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 33:1014-9. 2013
  2. pmc Ribosomal protein L17, RpL17, is an inhibitor of vascular smooth muscle growth and carotid intima formation
    Elaine M Smolock
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circulation 126:2418-27. 2012
  3. pmc Acetylation of cyclophilin A is required for its secretion and vascular cell activation
    Nwe Nwe Soe
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Box CVRI, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Cardiovasc Res 101:444-53. 2014
  4. ncbi request reprint Cyclophilin A is an important mediator of platelet function by regulating integrin αIIbβ3 bidirectional signalling
    Lian Wang
    Bradford C Berk, MD, PhD, Aab Cardiovascular Research Institute, University of Rochester, Box CVRI, 601 Elmwood Avenue, Rochester, NY 14642, USA, Tel 1 585 275 3407, Fax 1 585 273 1059, E mail
    Thromb Haemost 111:873-82. 2014
  5. pmc Cyclophilin A is required for angiotensin II-induced p47phox translocation to caveolae in vascular smooth muscle cells
    Nwe Nwe Soe
    Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Arterioscler Thromb Vasc Biol 33:2147-53. 2013
  6. pmc Gas6-Axl pathway: the role of redox-dependent association of Axl with nonmuscle myosin IIB
    Megan E Cavet
    Aab Cardiovascular Research Institute, University of Rochester, Box 679, Rochester, NY 14642, USA
    Hypertension 56:105-11. 2010
  7. pmc Genetic locus on mouse chromosome 7 controls elevated heart rate
    Elaine M Smolock
    Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Physiol Genomics 44:689-98. 2012
  8. pmc Phosphorylation of G protein-coupled receptor kinase 2-interacting protein 1 tyrosine 392 is required for phospholipase C-gamma activation and podosome formation in vascular smooth muscle cells
    Jing Wang
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 30:1976-82. 2010

Collaborators

Detail Information

Publications8

  1. pmc Identification of a genetic locus on chromosome 11 that regulates leukocyte infiltration in mouse carotid artery
    Elaine M Smolock
    University of Rochester, Aab Cardiovascular Research Institute, 601 Elmwood Ave, Box CVRI, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 33:1014-9. 2013
    ..We hypothesized that the extent of inflammation associated with intima-media thickening is a genetically regulated trait...
  2. pmc Ribosomal protein L17, RpL17, is an inhibitor of vascular smooth muscle growth and carotid intima formation
    Elaine M Smolock
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circulation 126:2418-27. 2012
    ..The purpose of this study was to identify candidate genes contributing to intima formation...
  3. pmc Acetylation of cyclophilin A is required for its secretion and vascular cell activation
    Nwe Nwe Soe
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Box CVRI, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Cardiovasc Res 101:444-53. 2014
    ..Recently, it was shown that acetylated CyPA (AcK-CyPA) affects its function. We investigated the role of acetylation of CyPA for its secretion and signalling in vascular cells...
  4. ncbi request reprint Cyclophilin A is an important mediator of platelet function by regulating integrin αIIbβ3 bidirectional signalling
    Lian Wang
    Bradford C Berk, MD, PhD, Aab Cardiovascular Research Institute, University of Rochester, Box CVRI, 601 Elmwood Avenue, Rochester, NY 14642, USA, Tel 1 585 275 3407, Fax 1 585 273 1059, E mail
    Thromb Haemost 111:873-82. 2014
    ..In conclusion, CyPA is an important mediator in platelet function by regulation of αIIbβ3 bidirectionalsignalling through increased ROS production and facilitating interaction between αIIbβ3 and the cell cytoskeleton. ..
  5. pmc Cyclophilin A is required for angiotensin II-induced p47phox translocation to caveolae in vascular smooth muscle cells
    Nwe Nwe Soe
    Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Arterioscler Thromb Vasc Biol 33:2147-53. 2013
    ..We hypothesized that CyPA regulates AngII-induced ROS generation by promoting translocation of NADPH oxidase cytosolic subunit p47phox to caveolae of the plasma membrane...
  6. pmc Gas6-Axl pathway: the role of redox-dependent association of Axl with nonmuscle myosin IIB
    Megan E Cavet
    Aab Cardiovascular Research Institute, University of Rochester, Box 679, Rochester, NY 14642, USA
    Hypertension 56:105-11. 2010
    ..This interaction provides a direct link between Axl and molecular motors crucial for directed cell migration, which may mediate increased migration in vascular dysfunction...
  7. pmc Genetic locus on mouse chromosome 7 controls elevated heart rate
    Elaine M Smolock
    Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Physiol Genomics 44:689-98. 2012
    ..The peak association was observed for 17 SNPs that are localized within three GABA(A) receptor genes. In summary, we used a combined genetic approach to fine map a novel elevated HR locus on mouse chromosome 7...
  8. pmc Phosphorylation of G protein-coupled receptor kinase 2-interacting protein 1 tyrosine 392 is required for phospholipase C-gamma activation and podosome formation in vascular smooth muscle cells
    Jing Wang
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Arterioscler Thromb Vasc Biol 30:1976-82. 2010
    ..In this study, we identified specific GIT1 tyrosines required for PLCγ activation and podosome formation in vascular smooth muscle cells (VSMC)...