Pamela L Smithburger

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. doi request reprint QT prolongation in the intensive care unit: commonly used medications and the impact of drug-drug interactions
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, Critical Care Pharmacist, Medical Intensive Care Unit, University of Pittsburgh Medical Center, 200 Lothrop Street, PFG 01 01 01, Pittsburgh, PA 15213, USA
    Expert Opin Drug Saf 9:699-712. 2010
  2. doi request reprint Interpatient variability in dexmedetomidine response: a survey of the literature
    Samantha F Holliday
    University of Pittsburgh School of Pharmacy, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    ScientificWorldJournal 2014:805013. 2014
  3. ncbi request reprint Alteplase treatment of acute pulmonary embolism in the intensive care unit
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh PA 15213, USA
    Crit Care Nurse 33:17-27. 2013
  4. doi request reprint Drug-drug interactions in the medical intensive care unit: an assessment of frequency, severity and the medications involved
    Pamela L Smithburger
    Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA
    Int J Pharm Pract 20:402-8. 2012
  5. doi request reprint Comparing effectiveness of 3 learning strategies: simulation-based learning, problem-based learning, and standardized patients
    Pamela L Smithburger
    Department of Pharmacy and Therapeutics, UPMC Presbyterian Shadyside, Pittsburgh, PA 15213, USA
    Simul Healthc 7:141-6. 2012
  6. doi request reprint A critical evaluation of clinical decision support for the detection of drug-drug interactions
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, Department of Pharmacy and Therapeutics, Critical Care Pharmacist, Medical Intensive Care Unit, UPMC, Pittsburgh, PA, USA
    Expert Opin Drug Saf 10:871-82. 2011
  7. doi request reprint Grading the severity of drug-drug interactions in the intensive care unit: a comparison between clinician assessment and proprietary database severity rankings
    Pamela L Smithburger
    University of Pittsburgh Medical Center, PA, USA
    Ann Pharmacother 44:1718-24. 2010
  8. doi request reprint Recent advances in the treatment of hypertensive emergencies
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15213, USA
    Crit Care Nurse 30:24-30; quiz 31. 2010
  9. doi request reprint Drug-drug interactions in cardiac and cardiothoracic intensive care units: an analysis of patients in an academic medical centre in the US
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, and Medical Intensive Care Unit, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Drug Saf 33:879-88. 2010
  10. doi request reprint Drug-drug interactions contributing to QT prolongation in cardiac intensive care units
    Michael J Armahizer
    Cardiothoracic Intensive Care Unit, UPMC, Pittsburgh, PA, USA
    J Crit Care 28:243-9. 2013

Collaborators

Detail Information

Publications16

  1. doi request reprint QT prolongation in the intensive care unit: commonly used medications and the impact of drug-drug interactions
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, Critical Care Pharmacist, Medical Intensive Care Unit, University of Pittsburgh Medical Center, 200 Lothrop Street, PFG 01 01 01, Pittsburgh, PA 15213, USA
    Expert Opin Drug Saf 9:699-712. 2010
    ..Additional DDI education and a review of management strategies could assist with prevention of future adverse outcomes...
  2. doi request reprint Interpatient variability in dexmedetomidine response: a survey of the literature
    Samantha F Holliday
    University of Pittsburgh School of Pharmacy, 3501 Terrace Street, Pittsburgh, PA 15261, USA
    ScientificWorldJournal 2014:805013. 2014
    ..To fully understand the role of dexmedetomidine, it is vital to further evaluate what prompts such marked interpatient variability in critically ill patients. ..
  3. ncbi request reprint Alteplase treatment of acute pulmonary embolism in the intensive care unit
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh PA 15213, USA
    Crit Care Nurse 33:17-27. 2013
    ..Clinical pearls for the administration, monitoring, and care of a patient receiving alteplase in an intensive care unit also are discussed...
  4. doi request reprint Drug-drug interactions in the medical intensive care unit: an assessment of frequency, severity and the medications involved
    Pamela L Smithburger
    Department of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA
    Int J Pharm Pract 20:402-8. 2012
    ..Currently, there is a lack of literature describing DDIs in the intensive care unit (ICU). The purpose of this study is to evaluate frequency, severity and drug combinations involved in DDIs occurring in a medical ICU (MICU)...
  5. doi request reprint Comparing effectiveness of 3 learning strategies: simulation-based learning, problem-based learning, and standardized patients
    Pamela L Smithburger
    Department of Pharmacy and Therapeutics, UPMC Presbyterian Shadyside, Pittsburgh, PA 15213, USA
    Simul Healthc 7:141-6. 2012
    ..Several learning strategies, including problem-based learning (PBL), standardized patients, and high-fidelity human simulation, have been incorporated into courses; however, it is currently unknown which technique is the most effective...
  6. doi request reprint A critical evaluation of clinical decision support for the detection of drug-drug interactions
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, Department of Pharmacy and Therapeutics, Critical Care Pharmacist, Medical Intensive Care Unit, UPMC, Pittsburgh, PA, USA
    Expert Opin Drug Saf 10:871-82. 2011
    ..The generation of DDI alerts is one aspect of CDSS that may improve patient safety and reduce adverse drug events...
  7. doi request reprint Grading the severity of drug-drug interactions in the intensive care unit: a comparison between clinician assessment and proprietary database severity rankings
    Pamela L Smithburger
    University of Pittsburgh Medical Center, PA, USA
    Ann Pharmacother 44:1718-24. 2010
    ..A DDI alert system based on severity rankings has been shown to reduce alert fatigue; however, the best method to populate this type of database is unclear...
  8. doi request reprint Recent advances in the treatment of hypertensive emergencies
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15213, USA
    Crit Care Nurse 30:24-30; quiz 31. 2010
    ..The application of knowledge of treatment goals, hemodynamic monitoring, and pharmacological therapy for hypertensive emergencies can lead to the safe recovery of these critically ill patients...
  9. doi request reprint Drug-drug interactions in cardiac and cardiothoracic intensive care units: an analysis of patients in an academic medical centre in the US
    Pamela L Smithburger
    University of Pittsburgh School of Pharmacy, and Medical Intensive Care Unit, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Drug Saf 33:879-88. 2010
    ..Knowing the clinically significant drug-drug interactions allows the opportunity for prevention through knowledge and computer-assisted programmes...
  10. doi request reprint Drug-drug interactions contributing to QT prolongation in cardiac intensive care units
    Michael J Armahizer
    Cardiothoracic Intensive Care Unit, UPMC, Pittsburgh, PA, USA
    J Crit Care 28:243-9. 2013
    ..To determine the most common drug-drug interaction (DDI) pairs contributing to QTc prolongation in cardiac intensive care units (ICUs)...
  11. doi request reprint Simulation-based learning versus problem-based learning in an acute care pharmacotherapy course
    Amy L Seybert
    Department of Pharmacy and Therapeutics, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Simul Healthc 7:162-5. 2012
    ..The objective of the study was to determine whether high-fidelity simulation is superior to problem-based learning (PBL) for training pharmacy students in an acute care elective...
  12. doi request reprint Improving adverse drug event detection in critically ill patients through screening intensive care unit transfer summaries
    Ananth M Anthes
    Surgical Intensive Care Unit, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pharmacoepidemiol Drug Saf 22:510-6. 2013
    ....
  13. pmc Transitioning knowledge gained from simulation to pharmacy practice
    Sandra L Kane-Gill
    School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Pharm Educ 75:210. 2011
    ..Educators should continue to be creative in the incorporation of simulation into pharmacy education and conduct more studies on the impact of simulation education on patient care to demonstrate the efficacy of this teaching modality...
  14. ncbi request reprint An evidence based systematic review of remifentanil associated opioid-induced hyperalgesia
    Ryan M Rivosecchi
    University of Pittsburgh Medical Center Presbyterian Campus, Pittsburgh, PA, USA
    Expert Opin Drug Saf 13:587-603. 2014
    ..Opioids are known for their side-effect profile, including bradycardia and respiratory depression; questions remain, however, regarding lesser known side effects such as opioid-induced hyperalgesia (OIH)...
  15. doi request reprint Pharmacologic and pharmacokinetic rationale for combination therapy in pulmonary arterial hypertension
    Roman Gokhman
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Cardiovasc Pharmacol 56:686-95. 2010
    ....
  16. ncbi request reprint Use of acetylcysteine for non-acetaminophen-induced acute liver failure
    Ibrahim Sales
    University of Pittsburgh Medical Center, USA
    Ann Hepatol 12:6-10. 2013
    ..It may be considered in non-transplant centers while awaiting referral or when transplantation is not an option. Further studies are necessary to determine optimal dosing, duration, and criteria for patient selection...