Wade S Smith

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurocrit Care 4:14-7. 2006
  2. ncbi Emergency treatment of acute ischemic stroke: expanding the time window
    Raul G Nogueira
    Wade S Smith, MD, PhD Department of Neurology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Curr Treat Options Neurol 11:433-43. 2009
  3. ncbi Technology Insight: recanalization with drugs and devices during acute ischemic stroke
    Wade S Smith
    University of California, San Francisco, CA 94143 0114, USA
    Nat Clin Pract Neurol 3:45-53. 2007
  4. ncbi Significance of large vessel intracranial occlusion causing acute ischemic stroke and TIA
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Stroke 40:3834-40. 2009
  5. ncbi Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial
    Wade S Smith
    Department of Neurology, University of California, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 36:1432-8. 2005
  6. ncbi Intra-arterial thrombolytic therapy for acute basilar occlusion: pro
    Wade S Smith
    Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 0114, USA
    Stroke 38:701-3. 2007
  7. ncbi Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial
    Wade S Smith
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 39:1205-12. 2008
  8. ncbi Hyperdense basilar artery sign on unenhanced CT predicts thrombus and outcome in acute posterior circulation stroke
    Gregory V Goldmakher
    Massachusetts General Hospital, Department of Neurology, MGH Stroke Research Center, 175 Cambridge Street, suite 300 Boston, MA 02114, USA
    Stroke 40:134-9. 2009
  9. ncbi The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion
    Fabricio O Lima
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Boston, Mass 02114, USA
    Stroke 41:2316-22. 2010
  10. ncbi Visual grading system for vasospasm based on perfusion CT imaging: comparisons with conventional angiography and quantitative perfusion CT
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143, USA
    Cerebrovasc Dis 26:163-70. 2008

Detail Information

Publications63

  1. ncbi Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurocrit Care 4:14-7. 2006
    ..Because large-vessel occlusion and stroke severity are likely correlated, it is unclear if largevessel occlusion independently predicts outcome or is simply a marker for stroke severity...
  2. ncbi Emergency treatment of acute ischemic stroke: expanding the time window
    Raul G Nogueira
    Wade S Smith, MD, PhD Department of Neurology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Curr Treat Options Neurol 11:433-43. 2009
    ..5 to 8 hours, and perhaps up to 12 to 24 hours for basilar occlusions...
  3. ncbi Technology Insight: recanalization with drugs and devices during acute ischemic stroke
    Wade S Smith
    University of California, San Francisco, CA 94143 0114, USA
    Nat Clin Pract Neurol 3:45-53. 2007
    ..This design will allow any patient timely access to state-of-the-art stroke treatment tailored to their needs...
  4. ncbi Significance of large vessel intracranial occlusion causing acute ischemic stroke and TIA
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Stroke 40:3834-40. 2009
    ..Because little prospective angiographic data have been reported on a cohort of unselected patients with stroke and with transient ischemic attack, the clinical impact of LVO has been difficult to quantify...
  5. ncbi Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial
    Wade S Smith
    Department of Neurology, University of California, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 36:1432-8. 2005
    ..An alternative strategy for opening intracranial vessels during stroke is mechanical embolectomy, especially for patients ineligible for intravenous tPA...
  6. ncbi Intra-arterial thrombolytic therapy for acute basilar occlusion: pro
    Wade S Smith
    Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 0114, USA
    Stroke 38:701-3. 2007
    ....
  7. ncbi Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial
    Wade S Smith
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 39:1205-12. 2008
    ..Enhancements in embolectomy device design may improve recanalization rates...
  8. ncbi Hyperdense basilar artery sign on unenhanced CT predicts thrombus and outcome in acute posterior circulation stroke
    Gregory V Goldmakher
    Massachusetts General Hospital, Department of Neurology, MGH Stroke Research Center, 175 Cambridge Street, suite 300 Boston, MA 02114, USA
    Stroke 40:134-9. 2009
    ..Our purpose was to determine whether the hyperdense basilar artery (HDBA) sign has utility in detecting thrombosis and predicting outcome in patients presenting with signs and symptoms of posterior circulation stroke...
  9. ncbi The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion
    Fabricio O Lima
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Boston, Mass 02114, USA
    Stroke 41:2316-22. 2010
    ..The role of noninvasive methods in the evaluation of collateral circulation has yet to be defined. We hypothesized that a favorable pattern of leptomeningeal collaterals, as identified by CT angiography, correlates with improved outcomes...
  10. ncbi Visual grading system for vasospasm based on perfusion CT imaging: comparisons with conventional angiography and quantitative perfusion CT
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143, USA
    Cerebrovasc Dis 26:163-70. 2008
    ..The purpose of this study was to compare simple visual grading of perfusion CT (PCT) maps to a more quantitative, threshold-based interpretation of PCT parameters in the characterization of presence and severity of vasospasm...
  11. ncbi National Institutes of Health Stroke Scale score is poorly predictive of proximal occlusion in acute cerebral ischemia
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Stroke 40:2988-93. 2009
    ..Use of National Institutes of Health Stroke Scale (NIHSS) score to predict a proximal arterial occlusion (PO) is suggested by several case series as a viable method of selecting cases appropriate for multimodal imaging...
  12. ncbi Phase-contrast magnetic resonance imaging measurements in intracranial aneurysms in vivo of flow patterns, velocity fields, and wall shear stress: comparison with computational fluid dynamics
    Loic Boussel
    Radiology Service, VA Medical Center, San Francisco, California 94121, USA
    Magn Reson Med 61:409-17. 2009
    ..These results indicate that 7D-MRV can be used in vivo to measure velocity flow fields and for estimating MSS and WSS. Currently, however, this method cannot accurately quantify the latter two parameters...
  13. ncbi Cardiovascular predictors of in-patient mortality after subarachnoid hemorrhage
    Sirisha Yarlagadda
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143-0124, USA
    Neurocrit Care 5:102-7. 2006
    ..Though these effects may be explained by a reduction in cerebral perfusion pressure or other mechanisms, further research is required to determine whether or not they are causal in nature...
  14. ncbi Hypernatremia predicts adverse cardiovascular and neurological outcomes after SAH
    Landis A Fisher
    Division of Cardiology, UCSF Medical Center, San Francisco, CA, USA
    Neurocrit Care 5:180-5. 2006
    ..075). CONCLUSION: In the acute period after SAH, hypernatremia is associated with adverse cardiac outcomes and death. SAH patients with hypernatremia should be monitored for evidence of cardiac dysfunction...
  15. ncbi Prospective evaluation of multidetector-row CT angiography for the diagnosis of vasospasm following subarachnoid hemorrhage: a comparison with digital subtraction angiography
    Saadia R Chaudhary
    Neuroradiology Section, Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Cerebrovasc Dis 25:144-50. 2008
    ..To evaluate the accuracy of multidetector-row CT angiography (CTA) for the diagnosis of large-vessel vasospasm following subarachnoid hemorrhage by comparison to digital subtraction angiography (DSA)...
  16. ncbi Predictors of good clinical outcomes, mortality, and successful revascularization in patients with acute ischemic stroke undergoing thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI Trials
    Raul G Nogueira
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Stroke 40:3777-83. 2009
    ..We sought to determine the predictors of clinical and angiographic outcomes in these patients...
  17. ncbi Predictors of left ventricular regional wall motion abnormalities after subarachnoid hemorrhage
    Avinash Kothavale
    Division of Cardiology, UCSF Medical Center, San Francisco, CA, USA
    Neurocrit Care 4:199-205. 2006
    ..34 per 10 bpm increase, p = 0.024) were predictive of RWMA. CONCLUSIONS: RWMA were frequent after SAH. High-grade SAH, an elevation in cTi levels, a history of prior stimulant drug use, and tachycardia are independent predictors of RWMA...
  18. ncbi Temporal stability of dysmorphic fusiform aneurysms of the intracranial internal carotid artery
    Loic Boussel
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
    J Vasc Interv Radiol 22:1007-11. 2011
    ....
  19. ncbi Effect of time to reperfusion on clinical outcome of anterior circulation strokes treated with thrombectomy: pooled analysis of the MERCI and Multi MERCI trials
    Raul G Nogueira
    Department of Neurology, Neurosurgery, and Radiology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA
    Stroke 42:3144-9. 2011
    ..We sought to establish how time influences outcomes in anterior circulation proximal arterial occlusions...
  20. ncbi Perfusion CT compared to H(2) (15)O/O (15)O PET in patients with chronic cervical carotid artery occlusion
    Amita Kamath
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Neuroradiology 50:745-51. 2008
    ..The purpose of this study was to compare the results of perfusion computed tomography (PCT) with those of (15)O(2)/H(2) (15)O positron emission tomography (PET) in a subset of Carotid Occlusion Surgery Study (COSS) patients...
  21. ncbi Improvement in intensive care unit outcomes in patients with subarachnoid hemorrhage after initiation of neurointensivist co-management
    S Andrew Josephson
    Department of Neurology, University of California, San Francisco, California 94143, USA
    J Neurosurg 112:626-30. 2010
    ..No study to date has examined the role of neurointensivists specifically in subarachnoid hemorrhage (SAH) management. This study examined the use of a team-based neurointensivist co-management approach...
  22. ncbi Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
    AJNR Am J Neuroradiol 26:104-12. 2005
    ..2%, 91.8%, and 87.9% in showing the extent. CONCLUSION: Dynamic PCT maps are more accurate than nonenhanced CT in detecting hemispheric strokes. Despite limited spatial coverage, PCT is highly reliable to assess the stroke extent...
  23. ncbi Collateral vessels on CT angiography predict outcome in acute ischemic stroke
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Stroke 40:3001-5. 2009
    ....
  24. ncbi Gender differences in outcomes after ischemic stroke: role of ischemic lesion volume and intracranial large-artery occlusion
    Gisele S Silva
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Cerebrovasc Dis 30:470-5. 2010
    ..The reasons for gender disparities in stroke outcome remain unclear, and little is known about the value of acute neuroimaging characteristics in elucidating differential stroke outcomes between the sexes...
  25. ncbi Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage
    Pam R Taub
    Department of Medicine, Cardiology Division, University of California, San Diego, CA 94114, USA
    Neurocrit Care 15:13-8. 2011
    ..We sought to determine whether elevated levels of BNP are independently associated with radiographic cerebral infarction after SAH...
  26. ncbi The prognosis for aphasia in stroke
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Stroke Cerebrovasc Dis 21:350-7. 2012
    ..The purpose of this study is to assess the prognosis for recovery of language function in subjects presenting with aphasia caused by ischemic stroke within 12 hours of symptom onset...
  27. ncbi Initial Glasgow Coma Scale score predicts outcome following thrombolysis for posterior circulation stroke
    Jack W Tsao
    Department of Neurology, San Francisco General Hospital, San Francisco, Calif, USA
    Arch Neurol 62:1126-9. 2005
    ..Consequently, there is less published information on thrombolytic therapy for posterior circulation stroke...
  28. ncbi Density of thrombus on admission CT predicts revascularization efficacy in large vessel occlusion acute ischemic stroke
    Parham Moftakhar
    Departments of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
    Stroke 44:243-5. 2013
    ..Can lysability of large vessel thrombi in acute ischemic stroke be predicted by measuring clot density on admission nonenhanced CT (NECT), postcontrast enhanced CT, or CT angiogram (CTA)?..
  29. ncbi Reperfusion is a more accurate predictor of follow-up infarct volume than recanalization: a proof of concept using CT in acute ischemic stroke patients
    Bruno P Soares
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Stroke 41:e34-40. 2010
    ..Material and..
  30. ncbi Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage
    Wade S Smith
    Department of Neurology, University of California, San Francisco, Calif 94134 0114, USA
    Stroke 35:2518-22. 2004
    ..Papaverine is used to vasodilate cerebral arteries undergoing vasospasm from subarachnoid hemorrhage. However, papaverine inhibits cellular respiration in vitro and could cause neurotoxicity in humans...
  31. ncbi Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients
    Jessica C Tan
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143 0628, USA
    Ann Neurol 61:533-43. 2007
    ....
  32. ncbi Safety and feasibility of a CT protocol for acute stroke: combined CT, CT angiography, and CT perfusion imaging in 53 consecutive patients
    Wade S Smith
    Department of Neurology, University of California, San Francisco, 94143, USA
    AJNR Am J Neuroradiol 24:688-90. 2003
    ..High-speed, multisection, helical CT scanners allow rapid, safe imaging of the entire neurovascular axis in patients with acute stroke by use of combined CT imaging, CT perfusion imaging, and CTA...
  33. ncbi Continuous bleeding from a basilar terminus aneurysm imaged with CT angiography and conventional angiography
    S Andrew Josephson
    Department of Neurology, University of California, San Francisco, CA 94143-0114, USA
    Neurocrit Care 1:103-6. 2004
    ..Continued bleeding from an intracranial aneurysm is a rare event that can be recognized using computed tomography angiography and likely indicates a poor prognosis...
  34. ncbi How accurate is CT angiography in evaluating intracranial atherosclerotic disease?
    Mai N Nguyen-Huynh
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Stroke 39:1184-8. 2008
    ..However, it is invasive and can only be carried out at specialized centers. We sought to compare CT angiography (CTA) to DSA for detection and measurement of stenosis in large intracranial arteries...
  35. ncbi Trevo versus Merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial
    Raul G Nogueira
    Department of Neurology, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA 30303, USA
    Lancet 380:1231-40. 2012
    ..We compared efficacy and safety of the Trevo Retriever, a new stent-like device, with its US Food and Drug Administration-cleared predecessor, the Merci Retriever...
  36. ncbi Endothelial nitric oxide synthase polymorphism (-786T->C) and increased risk of angiographic vasospasm after aneurysmal subarachnoid hemorrhage
    Nerissa U Ko
    Department of Neurology, University of California, San Francisco, USA
    Stroke 39:1103-8. 2008
    ..Decreased availability of nitric oxide (NO) may be crucial in its pathogenesis. We hypothesized that endothelial NO synthase (eNOS) polymorphisms may determine susceptibility to vasospasm in SAH patients...
  37. ncbi Acute brain infarct: detection and delineation with CT angiographic source images versus nonenhanced CT scans
    Erica C S Camargo
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, GRB 239, Boston, MA 02114 2622, USA
    Radiology 244:541-8. 2007
    ....
  38. ncbi Comparison of mechanical embolectomy and intraarterial thrombolysis in acute ischemic stroke within the MCA: MERCI and Multi MERCI compared to PROACT II
    S Andrew Josephson
    Department of Neurology, University of California, San Francisco, CA, 94143 0114, USA
    Neurocrit Care 10:43-9. 2009
    ..Differences in trial design may account for this mortality difference...
  39. ncbi Incidence of contrast nephropathy from cerebral CT angiography and CT perfusion imaging
    S Andrew Josephson
    Department of Neurology, University of California, San Francisco, USA
    Neurology 64:1805-6. 2005
    ..37%), the administration of IV contrast medium possibly contributed to renal failure. Two patients (0.19%) received temporary hemodialysis during hospitalization. The incidence of contrast nephropathy in neurovascular patients is low...
  40. ncbi Local cortical hypoperfusion imaged with CT perfusion during postictal Todd's paresis
    Marlon S Mathews
    Department of Neurological Surgery, University of California, Irvine, CA, USA
    Neuroradiology 50:397-401. 2008
    ..However, it is unclear whether the pathophysiology of Todd's paralysis is related to alterations in cerebral perfusion. We report CT perfusion findings in a patient presenting with postictal aphasia and right hemiparesis...
  41. ncbi Intracranial large vessel occlusion as a predictor of decline in functional status after transient ischemic attack
    Sharon N Poisson
    Department of Neurology, University of California, San Francisco, CA, USA
    Stroke 42:44-7. 2011
    ..Intracranial large vessel occlusion (LVO) predicts poor outcome after stroke, but the natural history of symptomatic intracranial LVO in patients with TIA is unknown...
  42. ncbi Mechanical thrombectomy of intracranial internal carotid occlusion: pooled results of the MERCI and Multi MERCI Part I trials
    Alexander C Flint
    Department of Neurology, University of California, San Francisco, San Francisco CA 94143 0114, USA
    Stroke 38:1274-80. 2007
    ....
  43. ncbi Cerebral blood flow changes after endovascular treatment of cerebrovascular stenoses
    Nerissa U Ko
    Department of Neurology, University of California, San Francisco 94110, USA
    AJNR Am J Neuroradiol 26:538-42. 2005
    ..However, the increased CBF appeared to be unrelated to the degree of vascular stenosis, suggesting a relationship to availability of collateral flow pathways or a neurogenic influence...
  44. ncbi Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA 94110, USA
    AJNR Am J Neuroradiol 26:1095-100. 2005
    ....
  45. ncbi Dynamic perfusion CT: optimizing the temporal resolution and contrast volume for calculation of perfusion CT parameters in stroke patients
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
    AJNR Am J Neuroradiol 25:720-9. 2004
    ..CONCLUSION: Temporal sampling intervals greater than 1 second can be used without altering the quantitative accuracy of PCT. Increased sampling intervals reduce the radiation dose and may allow for increased spatial coverage...
  46. ncbi Cardiac injury after subarachnoid hemorrhage is independent of the type of aneurysm therapy
    Jacob C Miss
    Department of Medicine, University of California, San Francisco, California 94143-0124, USA
    Neurosurgery 55:1244-50; discussion 1250-1. 2004
    ..CONCLUSION: Surgical and endovascular aneurysm therapies were associated with similar risks of cardiac injury and dysfunction after SAH. The presence of neurocardiogenic injury should not affect aneurysm treatment decisions...
  47. ncbi Prevalence and implications of diastolic dysfunction after subarachnoid hemorrhage
    Alexander Kopelnik
    Division of Cardiology, University of California San Francisco Medical Center, San Francisco, CA 94143-0124, USA
    Neurocrit Care 3:132-8. 2005
    ..CONCLUSION: Diastolic dysfunction is common after SAH. It is associated with history of hypertension and older age and may explain the development of pulmonary edema in many SAH patients...
  48. ncbi Simultanagnosia through the eyes of an artist
    Wade S Smith
    Department of Neurology, University of California at San Francisco, CA 94143 0114, USA
    Neurology 60:1832-4. 2003
    ..Years later, her artistic abilities returned with only minor differences from those prior to her stroke...
  49. ncbi Effect of a US National Institutes of Health programme of clinical trials on public health and costs
    S Claiborne Johnston
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Lancet 367:1319-27. 2006
    ..The total costs and benefits to society of a clinical trial, the final step in testing an intervention, can be estimated by evaluating the effect of trial results on medical care and health...
  50. ncbi Cardiac rupture after intravenous t-PA administration in acute ischemic stroke
    Amar Dhand
    Department of Neurology, University of California San Francisco, 505 Parnassus Avenue, Box 0114, San Francisco, CA 94143 0114, USA
    Neurocrit Care 13:261-2. 2010
    ..Although described in MI patients who receive thrombolytic therapy, this complication is not well known in ischemic stroke patients who receive intravenous (IV) t-PA...
  51. ncbi Detection of atrial fibrillation and secondary stroke prevention using telemetry and ambulatory cardiac monitoring
    Hooman Kamel
    Department of Neurology, University of California, San Francisco, USA
    Curr Atheroscler Rep 13:338-43. 2011
    ..Even using current therapeutics, optimizing the diagnosis of AF remains a key component of quality care for patients with ischemic stroke...
  52. ncbi Cerebrovascular complications of methamphetamine abuse
    Emily L Ho
    Department of Neurology, University of California San Francisco, 1001 Potrero Ave, SFGH 4M62, Box 0870, San Francisco, CA 94143 0870, USA
    Neurocrit Care 10:295-305. 2009
    ....
  53. ncbi Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study
    Loic Boussel
    Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
    Stroke 39:2997-3002. 2008
    ..Low wall shear stress (WSS) has been reported to have a negative effect on endothelial cells normal physiology and may be an important contributor to local remodeling of the arterial wall and to aneurysm growth and rupture...
  54. ncbi Organ donation after cardiac death in amyotrophic lateral sclerosis
    Shahed Toossi
    Department of Neurology, University of California at San Francisco, USA
    Ann Neurol 71:154-6. 2012
    ..To our knowledge, this is the first report of organ donation in a patient with rapidly progressive ventilator-dependent ALS...
  55. ncbi Ventilator-associated pneumonia in a neurologic intensive care unit does not lead to increased mortality
    S Andrew Josephson
    Department of Neurology, University of California San Francisco, Box 0114, 505 Parnassus Avenue M 798, San Francisco, CA 94143 0114, USA
    Neurocrit Care 12:155-8. 2010
    ..Neurologic disease is a risk factor for VAP development, but the relationship between VAP and outcomes in patients admitted to the ICU for neurologic reasons remains largely unknown...
  56. ncbi Pathophysiology of focal cerebral ischemia: a therapeutic perspective
    Wade S Smith
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, California 94143 0114, USA
    J Vasc Interv Radiol 15:S3-12. 2004
    ..Herein, the author discusses the pathophysiology of focal cerebral ischemia as has been revealed in rodent models and reviews the major human trials according to treatment mechanism...
  57. ncbi Intermittent atrial fibrillation may account for a large proportion of otherwise cryptogenic stroke: a study of 30-day cardiac event monitors
    Lucas Elijovich
    Department of Neurology, Division of Stroke and Neurocritical Care, University of California San Francisco, San Francisco, CA 94143 0114, USA
    J Stroke Cerebrovasc Dis 18:185-9. 2009
    ..Thirty-day cardiac event monitors (30-DEM) may increase the rate of AF detection compared with standard investigations that include a combination of electrocardiography, cardiac telemetry, and short-term Holter monitoring...
  58. ncbi Regionalization of treatment for subarachnoid hemorrhage: a cost-utility analysis
    Naomi S Bardach
    School of Medicine, University of California, San Francisco, CA 94143-01, USA
    Circulation 109:2207-12. 2004
    ..However, current estimates of the impact of hospital volume on outcome require confirmation in more detailed cohort studies...
  59. ncbi Angioplasty for intracranial symptomatic vertebrobasilar ischemia
    Daryl R Gress
    Department of Neurology, University of California, San Francisco, 94143 0114, USA
    Neurosurgery 51:23-7; discussion 27-9. 2002
    ..This report reviews the clinical characteristics, indications, and procedural risks of intracranial angioplasty in a series of patients with symptomatic posterior circulation ischemia...
  60. ncbi Emergency neurological life support: traumatic spine injury
    Deborah M Stein
    University of Maryland School of Medicine, Baltimore, MD, USA
    Neurocrit Care 17:S102-11. 2012
    ..The initial emergency department clinical evaluation of possible spinal fractures and cord injuries, along with the definitive early management of confirmed injuries, are also covered...
  61. ncbi Factors influencing outcome and treatment effect in PROACT II
    Lawrence R Wechsler
    University of Pittsburgh, Pittsburgh, PA, USA
    Stroke 34:1224-9. 2003
    ..The purpose of the current study was to examine baseline factors to determine predictors of good outcome and response to treatment...
  62. ncbi An evidence-based causative classification system for acute ischemic stroke
    Hakan Ay
    A A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Ann Neurol 58:688-97. 2005
    ..The SSS-TOAST is a dynamic algorithm that can accommodate modifications as new epidemiological data accumulate and diagnostic techniques advance...
  63. ncbi Can emergency medicine physicians accurately identify i.v. t-PA eligible acute stroke patients?
    Wade S Smith
    Neurocrit Care 7:101-2. 2007