Wade S Smith

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial
    Wade S Smith
    Department of Neurology, University of California, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 36:1432-8. 2005
  2. doi request reprint Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial
    Wade S Smith
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 39:1205-12. 2008
  3. ncbi request reprint Technology Insight: recanalization with drugs and devices during acute ischemic stroke
    Wade S Smith
    University of California, San Francisco, CA 94143 0114, USA
    Nat Clin Pract Neurol 3:45-53. 2007
  4. ncbi request reprint Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurocrit Care 4:14-7. 2006
  5. ncbi request reprint Intra-arterial thrombolytic therapy for acute basilar occlusion: pro
    Wade S Smith
    Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 0114, USA
    Stroke 38:701-3. 2007
  6. pmc Significance of large vessel intracranial occlusion causing acute ischemic stroke and TIA
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Stroke 40:3834-40. 2009
  7. ncbi request reprint Emergency treatment of acute ischemic stroke: expanding the time window
    Raul G Nogueira
    Wade S Smith, MD, PhD Department of Neurology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Curr Treat Options Neurol 11:433-43. 2009
  8. doi request reprint The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion
    Fabricio O Lima
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Boston, Mass 02114, USA
    Stroke 41:2316-22. 2010
  9. doi request reprint Hyperdense basilar artery sign on unenhanced CT predicts thrombus and outcome in acute posterior circulation stroke
    Gregory V Goldmakher
    Massachusetts General Hospital, Department of Neurology, MGH Stroke Research Center, 175 Cambridge Street, suite 300 Boston, MA 02114, USA
    Stroke 40:134-9. 2009
  10. pmc National Institutes of Health Stroke Scale score is poorly predictive of proximal occlusion in acute cerebral ischemia
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Stroke 40:2988-93. 2009

Detail Information

Publications65

  1. ncbi request reprint Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial
    Wade S Smith
    Department of Neurology, University of California, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 36:1432-8. 2005
    ..An alternative strategy for opening intracranial vessels during stroke is mechanical embolectomy, especially for patients ineligible for intravenous tPA...
  2. doi request reprint Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial
    Wade S Smith
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Stroke 39:1205-12. 2008
    ..Enhancements in embolectomy device design may improve recanalization rates...
  3. ncbi request reprint Technology Insight: recanalization with drugs and devices during acute ischemic stroke
    Wade S Smith
    University of California, San Francisco, CA 94143 0114, USA
    Nat Clin Pract Neurol 3:45-53. 2007
    ..This design will allow any patient timely access to state-of-the-art stroke treatment tailored to their needs...
  4. ncbi request reprint Prognostic significance of angiographically confirmed large vessel intracranial occlusion in patients presenting with acute brain ischemia
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurocrit Care 4:14-7. 2006
    ..Because large-vessel occlusion and stroke severity are likely correlated, it is unclear if largevessel occlusion independently predicts outcome or is simply a marker for stroke severity...
  5. ncbi request reprint Intra-arterial thrombolytic therapy for acute basilar occlusion: pro
    Wade S Smith
    Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 0114, USA
    Stroke 38:701-3. 2007
    ....
  6. pmc Significance of large vessel intracranial occlusion causing acute ischemic stroke and TIA
    Wade S Smith
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Stroke 40:3834-40. 2009
    ..Because little prospective angiographic data have been reported on a cohort of unselected patients with stroke and with transient ischemic attack, the clinical impact of LVO has been difficult to quantify...
  7. ncbi request reprint Emergency treatment of acute ischemic stroke: expanding the time window
    Raul G Nogueira
    Wade S Smith, MD, PhD Department of Neurology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
    Curr Treat Options Neurol 11:433-43. 2009
    ..5 to 8 hours, and perhaps up to 12 to 24 hours for basilar occlusions...
  8. doi request reprint The pattern of leptomeningeal collaterals on CT angiography is a strong predictor of long-term functional outcome in stroke patients with large vessel intracranial occlusion
    Fabricio O Lima
    Stroke Service, Department of Neurology, Massachusetts General Hospital, Boston, Mass 02114, USA
    Stroke 41:2316-22. 2010
    ..The role of noninvasive methods in the evaluation of collateral circulation has yet to be defined. We hypothesized that a favorable pattern of leptomeningeal collaterals, as identified by CT angiography, correlates with improved outcomes...
  9. doi request reprint Hyperdense basilar artery sign on unenhanced CT predicts thrombus and outcome in acute posterior circulation stroke
    Gregory V Goldmakher
    Massachusetts General Hospital, Department of Neurology, MGH Stroke Research Center, 175 Cambridge Street, suite 300 Boston, MA 02114, USA
    Stroke 40:134-9. 2009
    ..Our purpose was to determine whether the hyperdense basilar artery (HDBA) sign has utility in detecting thrombosis and predicting outcome in patients presenting with signs and symptoms of posterior circulation stroke...
  10. pmc National Institutes of Health Stroke Scale score is poorly predictive of proximal occlusion in acute cerebral ischemia
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Stroke 40:2988-93. 2009
    ..Use of National Institutes of Health Stroke Scale (NIHSS) score to predict a proximal arterial occlusion (PO) is suggested by several case series as a viable method of selecting cases appropriate for multimodal imaging...
  11. ncbi request reprint Visual grading system for vasospasm based on perfusion CT imaging: comparisons with conventional angiography and quantitative perfusion CT
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143, USA
    Cerebrovasc Dis 26:163-70. 2008
    ..The purpose of this study was to compare simple visual grading of perfusion CT (PCT) maps to a more quantitative, threshold-based interpretation of PCT parameters in the characterization of presence and severity of vasospasm...
  12. pmc The prognosis for aphasia in stroke
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Stroke Cerebrovasc Dis 21:350-7. 2012
    ..The purpose of this study is to assess the prognosis for recovery of language function in subjects presenting with aphasia caused by ischemic stroke within 12 hours of symptom onset...
  13. pmc Phase-contrast magnetic resonance imaging measurements in intracranial aneurysms in vivo of flow patterns, velocity fields, and wall shear stress: comparison with computational fluid dynamics
    Loic Boussel
    Radiology Service, VA Medical Center, San Francisco, California 94121, USA
    Magn Reson Med 61:409-17. 2009
    ..These results indicate that 7D-MRV can be used in vivo to measure velocity flow fields and for estimating MSS and WSS. Currently, however, this method cannot accurately quantify the latter two parameters...
  14. pmc THRIVE score predicts outcomes with a third-generation endovascular stroke treatment device in the TREVO-2 trial
    Alexander C Flint
    From the Department of Neuroscience, Kaiser Permanente, Redwood City, CA A C F Department of Clinical Research, Prospect Analytical, San Jose, CA B X Departments of Neurology, Neurosurgery, and Radiology, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA R G, R G N Department of Neurology, Oregon Health and Science University, Portland, OR H L L Department of Neurology, UPMC Stroke Center, University of Pittsburgh Medical Center, PA T G J Department of Neurology, Stanford Stroke Center, Stanford University Medical Center, Palo Alto, CA G W A Department of Neurology, UCLA Stroke Center, University of California, Los Angeles, CA D S L Department of Neurology, University of Southern California, Los Angeles, CA N S and Department of Neurology, University of California, San Francisco, CA W S S
    Stroke 44:3370-5. 2013
    ..The TREVO-2 trial was a randomized controlled trial comparing a novel endovascular stroke treatment device (the Trevo device) to a previous-generation endovascular stroke treatment device (the Merci device)...
  15. ncbi request reprint Cardiovascular predictors of in-patient mortality after subarachnoid hemorrhage
    Sirisha Yarlagadda
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0124, USA
    Neurocrit Care 5:102-7. 2006
    ..The objective of this study was to test the hypothesis that cardiovascular abnormalities are independently related to in-patient mortality after SAH...
  16. ncbi request reprint Hypernatremia predicts adverse cardiovascular and neurological outcomes after SAH
    Landis A Fisher
    Division of Cardiology, UCSF Medical Center, San Francisco, CA, USA
    Neurocrit Care 5:180-5. 2006
    ..This study analyzed whether abnormal serum sodium levels are associated with cardiac outcomes and mortality after subarachnoid hemorrhage (SAH)...
  17. ncbi request reprint Predictors of left ventricular regional wall motion abnormalities after subarachnoid hemorrhage
    Avinash Kothavale
    Division of Cardiology, UCSF Medical Center, San Francisco, CA, USA
    Neurocrit Care 4:199-205. 2006
    ..The aim of this study was to determine the prevalence of LV regional wall motion abnormalities (RWMA) after SAH and to quantify the independent effects of specific demographic and clinical variables in predicting the development of RWMA...
  18. ncbi request reprint Predictors of good clinical outcomes, mortality, and successful revascularization in patients with acute ischemic stroke undergoing thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI Trials
    Raul G Nogueira
    Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA
    Stroke 40:3777-83. 2009
    ..We sought to determine the predictors of clinical and angiographic outcomes in these patients...
  19. ncbi request reprint Prospective evaluation of multidetector-row CT angiography for the diagnosis of vasospasm following subarachnoid hemorrhage: a comparison with digital subtraction angiography
    Saadia R Chaudhary
    Neuroradiology Section, Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Cerebrovasc Dis 25:144-50. 2008
    ..To evaluate the accuracy of multidetector-row CT angiography (CTA) for the diagnosis of large-vessel vasospasm following subarachnoid hemorrhage by comparison to digital subtraction angiography (DSA)...
  20. pmc Temporal stability of dysmorphic fusiform aneurysms of the intracranial internal carotid artery
    Loic Boussel
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
    J Vasc Interv Radiol 22:1007-11. 2011
    ....
  21. doi request reprint Effect of time to reperfusion on clinical outcome of anterior circulation strokes treated with thrombectomy: pooled analysis of the MERCI and Multi MERCI trials
    Raul G Nogueira
    Department of Neurology, Neurosurgery, and Radiology, Emory University School of Medicine, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA
    Stroke 42:3144-9. 2011
    ..We sought to establish how time influences outcomes in anterior circulation proximal arterial occlusions...
  22. pmc Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage
    Pam R Taub
    Department of Medicine, Cardiology Division, University of California, San Diego, CA 94114, USA
    Neurocrit Care 15:13-8. 2011
    ..We sought to determine whether elevated levels of BNP are independently associated with radiographic cerebral infarction after SAH...
  23. pmc Collateral vessels on CT angiography predict outcome in acute ischemic stroke
    Matthew B Maas
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass, USA
    Stroke 40:3001-5. 2009
    ....
  24. doi request reprint Improvement in intensive care unit outcomes in patients with subarachnoid hemorrhage after initiation of neurointensivist co-management
    S Andrew Josephson
    Department of Neurology, University of California, San Francisco, California 94143, USA
    J Neurosurg 112:626-30. 2010
    ..No study to date has examined the role of neurointensivists specifically in subarachnoid hemorrhage (SAH) management. This study examined the use of a team-based neurointensivist co-management approach...
  25. ncbi request reprint Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
    AJNR Am J Neuroradiol 26:104-12. 2005
    ..We determined the accuracy of these maps in patients with suspected acute hemispheric stroke...
  26. pmc Perfusion CT compared to H(2) (15)O/O (15)O PET in patients with chronic cervical carotid artery occlusion
    Amita Kamath
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Neuroradiology 50:745-51. 2008
    ..The purpose of this study was to compare the results of perfusion computed tomography (PCT) with those of (15)O(2)/H(2) (15)O positron emission tomography (PET) in a subset of Carotid Occlusion Surgery Study (COSS) patients...
  27. pmc Gender differences in outcomes after ischemic stroke: role of ischemic lesion volume and intracranial large-artery occlusion
    Gisele S Silva
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Cerebrovasc Dis 30:470-5. 2010
    ..The reasons for gender disparities in stroke outcome remain unclear, and little is known about the value of acute neuroimaging characteristics in elucidating differential stroke outcomes between the sexes...
  28. ncbi request reprint Initial Glasgow Coma Scale score predicts outcome following thrombolysis for posterior circulation stroke
    Jack W Tsao
    Department of Neurology, San Francisco General Hospital, San Francisco, Calif, USA
    Arch Neurol 62:1126-9. 2005
    ..Consequently, there is less published information on thrombolytic therapy for posterior circulation stroke...
  29. pmc Endothelial nitric oxide synthase polymorphism (-786T->C) and increased risk of angiographic vasospasm after aneurysmal subarachnoid hemorrhage
    Nerissa U Ko
    Department of Neurology, University of California, San Francisco, USA
    Stroke 39:1103-8. 2008
    ..Decreased availability of nitric oxide (NO) may be crucial in its pathogenesis. We hypothesized that endothelial NO synthase (eNOS) polymorphisms may determine susceptibility to vasospasm in SAH patients...
  30. doi request reprint Density of thrombus on admission CT predicts revascularization efficacy in large vessel occlusion acute ischemic stroke
    Parham Moftakhar
    Departments of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
    Stroke 44:243-5. 2013
    ..Can lysability of large vessel thrombi in acute ischemic stroke be predicted by measuring clot density on admission nonenhanced CT (NECT), postcontrast enhanced CT, or CT angiogram (CTA)?..
  31. pmc Reperfusion is a more accurate predictor of follow-up infarct volume than recanalization: a proof of concept using CT in acute ischemic stroke patients
    Bruno P Soares
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Stroke 41:e34-40. 2010
    ....
  32. ncbi request reprint Safety and feasibility of a CT protocol for acute stroke: combined CT, CT angiography, and CT perfusion imaging in 53 consecutive patients
    Wade S Smith
    Department of Neurology, University of California, San Francisco, 94143, USA
    AJNR Am J Neuroradiol 24:688-90. 2003
    ..High-speed, multisection, helical CT scanners allow rapid, safe imaging of the entire neurovascular axis in patients with acute stroke by use of combined CT imaging, CT perfusion imaging, and CTA...
  33. doi request reprint How accurate is CT angiography in evaluating intracranial atherosclerotic disease?
    Mai N Nguyen-Huynh
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Stroke 39:1184-8. 2008
    ..However, it is invasive and can only be carried out at specialized centers. We sought to compare CT angiography (CTA) to DSA for detection and measurement of stenosis in large intracranial arteries...
  34. ncbi request reprint Neurotoxicity of intra-arterial papaverine preserved with chlorobutanol used for the treatment of cerebral vasospasm after aneurysmal subarachnoid hemorrhage
    Wade S Smith
    Department of Neurology, University of California, San Francisco, Calif 94134 0114, USA
    Stroke 35:2518-22. 2004
    ..Papaverine is used to vasodilate cerebral arteries undergoing vasospasm from subarachnoid hemorrhage. However, papaverine inhibits cellular respiration in vitro and could cause neurotoxicity in humans...
  35. ncbi request reprint Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients
    Jessica C Tan
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143 0628, USA
    Ann Neurol 61:533-43. 2007
    ....
  36. ncbi request reprint Continuous bleeding from a basilar terminus aneurysm imaged with CT angiography and conventional angiography
    S Andrew Josephson
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurocrit Care 1:103-6. 2004
    ..Continued bleeding from an intracranial aneurysm is a rare event that can be recognized using computed tomography angiography and likely indicates a poor prognosis...
  37. pmc Trevo versus Merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial
    Raul G Nogueira
    Department of Neurology, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA 30303, USA
    Lancet 380:1231-40. 2012
    ..We compared efficacy and safety of the Trevo Retriever, a new stent-like device, with its US Food and Drug Administration-cleared predecessor, the Merci Retriever...
  38. ncbi request reprint Incidence of contrast nephropathy from cerebral CT angiography and CT perfusion imaging
    S Andrew Josephson
    Department of Neurology, University of California, San Francisco, USA
    Neurology 64:1805-6. 2005
    ..37%), the administration of IV contrast medium possibly contributed to renal failure. Two patients (0.19%) received temporary hemodialysis during hospitalization. The incidence of contrast nephropathy in neurovascular patients is low...
  39. doi request reprint Comparison of mechanical embolectomy and intraarterial thrombolysis in acute ischemic stroke within the MCA: MERCI and Multi MERCI compared to PROACT II
    S Andrew Josephson
    Department of Neurology, University of California, San Francisco, CA, 94143 0114, USA
    Neurocrit Care 10:43-9. 2009
    ..Differences in trial design may account for this mortality difference...
  40. ncbi request reprint Acute brain infarct: detection and delineation with CT angiographic source images versus nonenhanced CT scans
    Erica C S Camargo
    Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, GRB 239, Boston, MA 02114 2622, USA
    Radiology 244:541-8. 2007
    ....
  41. ncbi request reprint Mechanical thrombectomy of intracranial internal carotid occlusion: pooled results of the MERCI and Multi MERCI Part I trials
    Alexander C Flint
    Department of Neurology, University of California, San Francisco, San Francisco CA 94143 0114, USA
    Stroke 38:1274-80. 2007
    ....
  42. ncbi request reprint Cerebral blood flow changes after endovascular treatment of cerebrovascular stenoses
    Nerissa U Ko
    Department of Neurology, University of California, San Francisco 94110, USA
    AJNR Am J Neuroradiol 26:538-42. 2005
    ..We hypothesized that increases in cerebral blood flow (CBF) after endovascular stent placement are positively correlated with the severity of stenosis...
  43. ncbi request reprint Local cortical hypoperfusion imaged with CT perfusion during postictal Todd's paresis
    Marlon S Mathews
    Department of Neurological Surgery, University of California, Irvine, CA, USA
    Neuroradiology 50:397-401. 2008
    ..However, it is unclear whether the pathophysiology of Todd's paralysis is related to alterations in cerebral perfusion. We report CT perfusion findings in a patient presenting with postictal aphasia and right hemiparesis...
  44. doi request reprint Intracranial large vessel occlusion as a predictor of decline in functional status after transient ischemic attack
    Sharon N Poisson
    Department of Neurology, University of California, San Francisco, CA, USA
    Stroke 42:44-7. 2011
    ..Intracranial large vessel occlusion (LVO) predicts poor outcome after stroke, but the natural history of symptomatic intracranial LVO in patients with TIA is unknown...
  45. ncbi request reprint Prevalence and implications of diastolic dysfunction after subarachnoid hemorrhage
    Alexander Kopelnik
    Division of Cardiology, University of California San Francisco Medical Center, San Francisco, CA 94143 0124, USA
    Neurocrit Care 3:132-8. 2005
    ..Little is known about the occurrence of diastolic dysfunction in this setting. The purpose of this study was to determine the prevalence of diastolic dysfunction and its association with cardiac outcomes after SAH...
  46. ncbi request reprint Cardiac injury after subarachnoid hemorrhage is independent of the type of aneurysm therapy
    Jacob C Miss
    Department of Medicine, University of California, San Francisco, California 94143 0124, USA
    Neurosurgery 55:1244-50; discussion 1250-1. 2004
    ..It is hypothesized that aneurysm treatment does not affect the risk of developing cardiac injury and dysfunction...
  47. ncbi request reprint Dynamic perfusion CT: optimizing the temporal resolution and contrast volume for calculation of perfusion CT parameters in stroke patients
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
    AJNR Am J Neuroradiol 25:720-9. 2004
    ..Numerous parameters are involved in dynamic perfusion CT (PCT). We assessed the influence of the temporal sampling rate and the volume of contrast material...
  48. ncbi request reprint Relationship between brain tissue oxygen tension and CT perfusion: feasibility and initial results
    J Claude Hemphill
    Department of Neurology, University of California, San Francisco, CA 94110, USA
    AJNR Am J Neuroradiol 26:1095-100. 2005
    ..The purpose of this study was to determine if there is a relationship between CT perfusion (CTP) imaging parameters and P(br)O(2)...
  49. ncbi request reprint Simultanagnosia through the eyes of an artist
    Wade S Smith
    Department of Neurology, University of California at San Francisco, CA 94143 0114, USA
    Neurology 60:1832-4. 2003
    ..Years later, her artistic abilities returned with only minor differences from those prior to her stroke...
  50. ncbi request reprint Angioplasty for intracranial symptomatic vertebrobasilar ischemia
    Daryl R Gress
    Department of Neurology, University of California, San Francisco, 94143 0114, USA
    Neurosurgery 51:23-7; discussion 27-9. 2002
    ..This report reviews the clinical characteristics, indications, and procedural risks of intracranial angioplasty in a series of patients with symptomatic posterior circulation ischemia...
  51. pmc Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study
    Loic Boussel
    Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
    Stroke 39:2997-3002. 2008
    ..Low wall shear stress (WSS) has been reported to have a negative effect on endothelial cells normal physiology and may be an important contributor to local remodeling of the arterial wall and to aneurysm growth and rupture...
  52. doi request reprint Detection of atrial fibrillation and secondary stroke prevention using telemetry and ambulatory cardiac monitoring
    Hooman Kamel
    Department of Neurology, University of California, San Francisco, USA
    Curr Atheroscler Rep 13:338-43. 2011
    ..Even using current therapeutics, optimizing the diagnosis of AF remains a key component of quality care for patients with ischemic stroke...
  53. doi request reprint Cardiac rupture after intravenous t-PA administration in acute ischemic stroke
    Amar Dhand
    Department of Neurology, University of California San Francisco, 505 Parnassus Avenue, Box 0114, San Francisco, CA 94143 0114, USA
    Neurocrit Care 13:261-2. 2010
    ..Although described in MI patients who receive thrombolytic therapy, this complication is not well known in ischemic stroke patients who receive intravenous (IV) t-PA...
  54. doi request reprint Cerebrovascular complications of methamphetamine abuse
    Emily L Ho
    Department of Neurology, University of California San Francisco, 1001 Potrero Ave, SFGH 4M62, Box 0870, San Francisco, CA 94143 0870, USA
    Neurocrit Care 10:295-305. 2009
    ....
  55. ncbi request reprint Effect of a US National Institutes of Health programme of clinical trials on public health and costs
    S Claiborne Johnston
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Lancet 367:1319-27. 2006
    ..The total costs and benefits to society of a clinical trial, the final step in testing an intervention, can be estimated by evaluating the effect of trial results on medical care and health...
  56. doi request reprint Organ donation after cardiac death in amyotrophic lateral sclerosis
    Shahed Toossi
    Department of Neurology, University of California at San Francisco, USA
    Ann Neurol 71:154-6. 2012
    ..To our knowledge, this is the first report of organ donation in a patient with rapidly progressive ventilator-dependent ALS...
  57. doi request reprint Ventilator-associated pneumonia in a neurologic intensive care unit does not lead to increased mortality
    S Andrew Josephson
    Department of Neurology, University of California San Francisco, Box 0114, 505 Parnassus Avenue M 798, San Francisco, CA 94143 0114, USA
    Neurocrit Care 12:155-8. 2010
    ..Neurologic disease is a risk factor for VAP development, but the relationship between VAP and outcomes in patients admitted to the ICU for neurologic reasons remains largely unknown...
  58. ncbi request reprint Pathophysiology of focal cerebral ischemia: a therapeutic perspective
    Wade S Smith
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, California 94143 0114, USA
    J Vasc Interv Radiol 15:S3-12. 2004
    ..Herein, the author discusses the pathophysiology of focal cerebral ischemia as has been revealed in rodent models and reviews the major human trials according to treatment mechanism...
  59. doi request reprint Intermittent atrial fibrillation may account for a large proportion of otherwise cryptogenic stroke: a study of 30-day cardiac event monitors
    Lucas Elijovich
    Department of Neurology, Division of Stroke and Neurocritical Care, University of California San Francisco, San Francisco, CA 94143 0114, USA
    J Stroke Cerebrovasc Dis 18:185-9. 2009
    ..Thirty-day cardiac event monitors (30-DEM) may increase the rate of AF detection compared with standard investigations that include a combination of electrocardiography, cardiac telemetry, and short-term Holter monitoring...
  60. ncbi request reprint Regionalization of treatment for subarachnoid hemorrhage: a cost-utility analysis
    Naomi S Bardach
    School of Medicine, University of California, San Francisco, CA 94143 01, USA
    Circulation 109:2207-12. 2004
    ..Whether regionalization of care for SAH is cost-effective is unknown...
  61. ncbi request reprint Time from onset of SIRS to antibiotic administration and outcomes after subarachnoid hemorrhage
    Elan L Guterman
    Department of Neurology, Weill Cornell Medical College, 525 East 68th St, F610, New York, NY, 10065, USA
    Neurocrit Care 21:85-90. 2014
    ..We therefore hypothesized that SIRS would not be a suitable trigger for antibiotics in this population...
  62. ncbi request reprint Emergency neurological life support: traumatic spine injury
    Deborah M Stein
    University of Maryland School of Medicine, Baltimore, MD, USA
    Neurocrit Care 17:S102-11. 2012
    ..The initial emergency department clinical evaluation of possible spinal fractures and cord injuries, along with the definitive early management of confirmed injuries, are also covered...
  63. ncbi request reprint An evidence-based causative classification system for acute ischemic stroke
    Hakan Ay
    A A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Ann Neurol 58:688-97. 2005
    ..The SSS-TOAST is a dynamic algorithm that can accommodate modifications as new epidemiological data accumulate and diagnostic techniques advance...
  64. ncbi request reprint Can emergency medicine physicians accurately identify i.v. t-PA eligible acute stroke patients?
    Wade S Smith
    Neurocrit Care 7:101-2. 2007
  65. ncbi request reprint Factors influencing outcome and treatment effect in PROACT II
    Lawrence R Wechsler
    University of Pittsburgh, Pittsburgh, PA, USA
    Stroke 34:1224-9. 2003
    ..The purpose of the current study was to examine baseline factors to determine predictors of good outcome and response to treatment...