Nicholas Smith

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA
    BMC Med Genet 13:100. 2012
  2. ncbi request reprint The association of antihypertensive medication with serum creatinine changes in older adults
    N L Smith
    Department of Epidemiology, University of Washington, Seattle, USA
    Am J Hypertens 10:1368-77. 1997
  3. ncbi request reprint Glucose, blood pressure, and lipid control in older people with and without diabetes mellitus: the Cardiovascular Health Study
    Nicholas L Smith
    Department of Medicine, Cardiovascular Health Research Unit, University of Washington, 1730 Minor Avenue, Seattle, WA 98101, USA
    J Am Geriatr Soc 50:416-23. 2002
  4. ncbi request reprint Variation in 24 hemostatic genes and associations with non-fatal myocardial infarction and ischemic stroke
    N L Smith
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    J Thromb Haemost 6:45-53. 2008
  5. ncbi request reprint Association of genetic variations with nonfatal venous thrombosis in postmenopausal women
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, WA 98101, USA
    JAMA 297:489-98. 2007
  6. ncbi request reprint Conjugated equine estrogen, esterified estrogen, prothrombotic variants, and the risk of venous thrombosis in postmenopausal women
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    Arterioscler Thromb Vasc Biol 26:2807-12. 2006
  7. ncbi request reprint The association between time since last meal and blood pressure in older adults: the cardiovascular health study
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    J Am Geriatr Soc 51:824-8. 2003
  8. ncbi request reprint New-onset diabetes and risk of all-cause and cardiovascular mortality: the Cardiovascular Health Study
    Nicholas L Smith
    Cardiovascular Health Research Unit, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
    Diabetes Care 29:2012-7. 2006
  9. ncbi request reprint Serum potassium and stroke risk among treated hypertensive adults
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Am J Hypertens 16:806-13. 2003
  10. ncbi request reprint The burden of diabetes-associated cardiovascular hospitalizations in Veterans Administration (VA) and non-VA medical facilities
    Nicholas L Smith
    Seattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, Washington, USA
    Diabetes Care 27:B27-32. 2004

Detail Information

Publications70

  1. pmc MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample
    Jinying Zhao
    Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA
    BMC Med Genet 13:100. 2012
    ..This study investigates whether MAOA promoter methylation is associated with atherosclerosis, and whether this association is confounded by familial factors in a monozygotic (MZ) twin sample...
  2. ncbi request reprint The association of antihypertensive medication with serum creatinine changes in older adults
    N L Smith
    Department of Epidemiology, University of Washington, Seattle, USA
    Am J Hypertens 10:1368-77. 1997
    ....
  3. ncbi request reprint Glucose, blood pressure, and lipid control in older people with and without diabetes mellitus: the Cardiovascular Health Study
    Nicholas L Smith
    Department of Medicine, Cardiovascular Health Research Unit, University of Washington, 1730 Minor Avenue, Seattle, WA 98101, USA
    J Am Geriatr Soc 50:416-23. 2002
    ....
  4. ncbi request reprint Variation in 24 hemostatic genes and associations with non-fatal myocardial infarction and ischemic stroke
    N L Smith
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    J Thromb Haemost 6:45-53. 2008
    ..We hypothesized that common variation in 24 coagulation-fibrinolysis genes would contribute to risk of incident myocardial infarction (MI) or ischemic stroke (IS)...
  5. ncbi request reprint Association of genetic variations with nonfatal venous thrombosis in postmenopausal women
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, WA 98101, USA
    JAMA 297:489-98. 2007
    ....
  6. ncbi request reprint Conjugated equine estrogen, esterified estrogen, prothrombotic variants, and the risk of venous thrombosis in postmenopausal women
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    Arterioscler Thromb Vasc Biol 26:2807-12. 2006
    ..Esterified estrogen (EE), an alternative estrogenic compound, appears not to be associated with increased risk and nothing is known about the joint risk with prothrombotic genetic variants...
  7. ncbi request reprint The association between time since last meal and blood pressure in older adults: the cardiovascular health study
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    J Am Geriatr Soc 51:824-8. 2003
    ..To demonstrate a postprandial hypotensive (PPH) phenomenon in older adults...
  8. ncbi request reprint New-onset diabetes and risk of all-cause and cardiovascular mortality: the Cardiovascular Health Study
    Nicholas L Smith
    Cardiovascular Health Research Unit, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
    Diabetes Care 29:2012-7. 2006
    ..We hypothesized that risk of all-cause and cardiovascular mortality would be similar among participants with and without new-onset diabetes in the first years of follow-up and rise over time for new-onset diabetes...
  9. ncbi request reprint Serum potassium and stroke risk among treated hypertensive adults
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Am J Hypertens 16:806-13. 2003
    ..Stroke risk associated with more recent assessments of hypokalemia has not been examined...
  10. ncbi request reprint The burden of diabetes-associated cardiovascular hospitalizations in Veterans Administration (VA) and non-VA medical facilities
    Nicholas L Smith
    Seattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, Washington, USA
    Diabetes Care 27:B27-32. 2004
    ..This study examines the relative burden of cardiovascular disease in diabetic and nondiabetic admissions to Veterans Administration (VA) and non-VA hospitals...
  11. ncbi request reprint Cardiovascular risk factor control among veterans with diabetes: the ambulatory care quality improvement project
    Nicholas L Smith
    Seattle Epidemiologic Research and Information Center, VA Puget Sound Health Care System, Seattle, Washington, USA
    Diabetes Care 27:B33-8. 2004
    ..To describe the extent to which hyperglycemia, hypertension, and dyslipidemia are currently detected, treated, and controlled in U.S. veterans with diabetes with and without ischemic heart disease (IHD)...
  12. ncbi request reprint Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, USA
    JAMA 292:1581-7. 2004
    ..The findings from these trials, which used oral conjugated equine estrogens, may not be generalizable to other estrogen compounds...
  13. pmc Discovering novel risk factors for venous thrombosis: a candidate-gene approach
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, USA
    Thromb Res 123:S25-9. 2009
    ..As an example, we present a candidate-gene approach to identify novel associations between variation in 24 clotting genes and the risk of incident venous thrombosis...
  14. ncbi request reprint Fasting and 2-hour postchallenge serum glucose measures and risk of incident cardiovascular events in the elderly: the Cardiovascular Health Study
    Nicholas L Smith
    Cardiovascular Health Research Unit, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
    Arch Intern Med 162:209-16. 2002
    ..This study examined the relative predictive power of fasting and 2-hour glucose level on cardiovascular event risk...
  15. ncbi request reprint Time trends in the use of beta-blockers and other pharmacotherapies in older adults with congestive heart failure
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, Wash, USA
    Am Heart J 148:710-7. 2004
    ..We describe beta-blocker and other medication temporal treatment trends of CHF in the Cardiovascular Health Study, a community-based cohort study of 5888 adults > or =65 years of age...
  16. ncbi request reprint Temporal patterns in the medical treatment of congestive heart failure with angiotensin-converting enzyme inhibitors in older adults, 1989 through 1995
    N L Smith
    Department of Medicine, University of Washington, Seattle, USA
    Arch Intern Med 158:1074-80. 1998
    ..The extent to which clinical practice has adopted ACE inhibitor therapy is unknown...
  17. pmc Genetic predictors of fibrin D-dimer levels in healthy adults
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle 98101, USA
    Circulation 123:1864-72. 2011
    ..To identity genetic loci influencing D-dimer levels, we performed the first large-scale, genome-wide association search...
  18. ncbi request reprint Health outcomes associated with beta-blocker and diltiazem treatment of unstable angina
    N L Smith
    Department of Medicine, University of Washington, Seattle, USA
    J Am Coll Cardiol 32:1305-11. 1998
    ..We compared long-term health outcomes associated with beta-adrenergic blocking agents and diltiazem treatment for unstable angina...
  19. pmc Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis
    Nicholas L Smith
    Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, 1730 Minor Avenue, Seattle, WA 98101, USA
    Blood 117:6007-11. 2011
    ..Both STXBP5 and VWF findings were replicated successfully. Variation in genes associated with VWF levels in the genome-wide association study was found to be independently associated with incident VT...
  20. ncbi request reprint Antidiabetic treatment trends in a cohort of elderly people with diabetes. The cardiovascular health study, 1989-1997
    N L Smith
    Department of Medicine, University of Washington, Seattle, USA
    Diabetes Care 22:736-42. 1999
    ..This study characterizes the pharmaceutical treatment of type 2 diabetes from 1989-1990 to 1996-1997 in an elderly cohort...
  21. ncbi request reprint Temporal trends in the use of anticoagulants among older adults with atrial fibrillation
    N L Smith
    Department of Medicine, University of Washington, Seattle, USA
    Arch Intern Med 159:1574-8. 1999
    ..Insufficient documentation exists on the extent to which the use of these therapies following trial publications has continued to increase in the elderly with atrial fibrillation...
  22. ncbi request reprint The differential association of conjugated equine estrogen and esterified estrogen with activated protein C resistance in postmenopausal women
    N L Smith
    Department of Epidemiology, University of Washington, Seattle, WA 98101, USA
    J Thromb Haemost 4:1701-6. 2006
    ....
  23. ncbi request reprint Trends in the post-hospitalization medical treatment of unstable angina pectoris: 1990 to 1995
    N L Smith
    Department of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, USA
    Am J Cardiol 84:632-8. 1999
    ....
  24. pmc Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium
    Nicholas L Smith
    Cardiovascular Health Study Department of Epidemiology, University of Washington, Seattle, WA 98105, USA
    Circ Cardiovasc Genet 3:256-66. 2010
    ....
  25. pmc Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium
    Nicholas L Smith
    Department of Epidemiology, University of Washington, Seattle, Wash 98101, USA
    Circulation 121:1382-92. 2010
    ..Plasma levels of coagulation factors VII (FVII), VIII (FVIII), and von Willebrand factor (vWF) influence risk of hemorrhage and thrombosis. We conducted genome-wide association studies to identify new loci associated with plasma levels...
  26. pmc Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project
    JILL M JOHNSEN
    Department of Medicine, University of Washington, Seattle, WA, USA
    Blood 122:590-7. 2013
    ..Arg2287Trp were each associated with 30 to 40 IU/dL lower VWF level (P < .001). In summary, several common and rare VWF missense variants contribute to phenotypic differences in VWF and FVIII among AAs. ..
  27. ncbi request reprint Association of cholesterol with stroke risk varies in stroke subtypes and patient subgroups
    D L Tirschwell
    Department of Neurology, University of Washington, Seattle, USA
    Neurology 63:1868-75. 2004
    ..To perform a health maintenance organization-based case-control study to evaluate the association of total and high density lipoprotein (HDL) cholesterol with the risk of stroke subtypes and in patient subgroups...
  28. pmc Blood pressure level and incidence of myocardial infarction among patients treated for hypertension
    R C Kaplan
    Cardiovascular Health Research Unit, University of Washington, Seattle, USA
    Am J Public Health 89:1414-7. 1999
    ..This study examined the relationship between achieved blood pressure and risk of myocardial infarction among patients treated for hypertension...
  29. pmc Blood pressure control and risk of incident atrial fibrillation
    M C Thomas
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Am J Hypertens 21:1111-6. 2008
    ..We sought to determine whether the risk of incident AF among patients treated for hypertension differs by the degree of blood pressure control...
  30. pmc ABO genotype and risk of thrombotic events and hemorrhagic stroke
    K L Wiggins
    Department of Medicine, University of Washington, Seattle, WA 98101, USA
    J Thromb Haemost 7:263-9. 2009
    ..The non-O alleles of the ABO genotype have been associated with an increased risk of thrombosis. Risk associated with the specific A(1), A(2) or B alleles is not well defined...
  31. pmc Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study
    A P Reiner
    Department of Epidemiology, University of Washington, Seattle, WA 98195, USA
    J Thromb Haemost 7:1499-505. 2009
    ..Additional genetic factors are likely to underlie the etiology of VTE, some of which may become manifest at older ages...
  32. ncbi request reprint Body mass index and the risk of recurrent coronary events following acute myocardial infarction
    T D Rea
    Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington 98101, USA
    Am J Cardiol 88:467-72. 2001
    ..Thus, excess adiposity as measured by BMI was associated with an increased risk of recurrent coronary events following AMI, particularly among those who were obese...
  33. ncbi request reprint Hormone replacement therapy, prothrombotic mutations, and the risk of incident nonfatal myocardial infarction in postmenopausal women
    B M Psaty
    Cardiovascular Health Research Unit, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
    JAMA 285:906-13. 2001
    ....
  34. ncbi request reprint Control of blood pressure and risk of stroke among pharmacologically treated hypertensive patients
    O H Klungel
    Department of Epidemiology, Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, USA
    Stroke 31:420-4. 2000
    ..We estimated the proportion of strokes occurring among treated hypertensive patients that may be attributable to uncontrolled blood pressure...
  35. ncbi request reprint HMG CoA reductase inhibitors and the risk of venous thrombosis among postmenopausal women
    C J M Doggen
    Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA
    J Thromb Haemost 2:700-1. 2004
  36. pmc Lack of association between first myocardial infarction and past use of erythromycin, tetracycline, or doxycycline
    L A Jackson
    University of Washington, Seattle, USA
    Emerg Infect Dis 5:281-4. 1999
    ..These results suggest little or no association between the use of these antibiotics and the risk for first myocardial infarction in the primary prevention setting...
  37. ncbi request reprint Postmenopausal estrogens and risk of myocardial infarction in diabetic women
    R C Kaplan
    Cardiovascular Health Research Unit, University of Washington, Seattle 98101, USA
    Diabetes Care 21:1117-21. 1998
    ....
  38. ncbi request reprint Replacing short-acting nifedipine with alternative medications at a large health maintenance organization
    R C Kaplan
    Cardiovascular Health Research Unit, Department of Epidemiology, University of Washington, Seattle 98101, USA
    Am J Hypertens 11:471-7. 1998
    ..By presenting physicians and patients with recent evidence about the safety of short-acting nifedipine, a large health maintenance organization was able to motivate broad-scale changes to safer alternative drug therapies...
  39. ncbi request reprint Statins and cognitive function in the elderly: the Cardiovascular Health Study
    C Bernick
    Department of Medicine, University of Nevada School of Medicine, Las Vegas, NV 89102, USA
    Neurology 65:1388-94. 2005
    ..To examine the association of statin drug use on cognitive and MRI change in older adults...
  40. doi request reprint Use of alendronate and risk of incident atrial fibrillation in women
    Susan R Heckbert
    Cardiovascular Health Research Unit, University of Washington, 1730 Minor Ave, Ste 1360, Seattle, WA 98101 1448, USA
    Arch Intern Med 168:826-31. 2008
    ..This adverse effect was unexpected and had not been recognized previously...
  41. doi request reprint beta1- and beta2-adrenergic receptor gene variation, beta-blocker use and risk of myocardial infarction and stroke
    Rozenn N Lemaitre
    Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA
    Am J Hypertens 21:290-6. 2008
    ..The benefits of beta-blocker therapy may depend on underlying genetic susceptibility...
  42. pmc Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke
    Joshua C Bis
    Department of Medicine, University of Washington, Seattle, WA 981041, USA
    Atherosclerosis 198:166-73. 2008
    ....
  43. ncbi request reprint Hormone replacement therapy and associated risk of stroke in postmenopausal women
    Rozenn N Lemaitre
    Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle 98101, USA
    Arch Intern Med 162:1954-60. 2002
    ..There is little information about the risk of stroke in relation to time since initiation of hormone therapy and in relation to estrogen dose...
  44. ncbi request reprint Survival associated with two sets of diagnostic criteria for congestive heart failure
    Gina D Schellenbaum
    Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA
    Am J Epidemiol 160:628-35. 2004
    ..Compared with Cardiovascular Health Study central adjudication, Framingham criteria for CHF identified a larger group of participants with incident CHF, but all-cause mortality rates were similar across these diagnostic classifications...
  45. doi request reprint Common variation in cytochrome P450 epoxygenase genes and the risk of incident nonfatal myocardial infarction and ischemic stroke
    Kristin D Marciante
    Cardiovascular Health Research Unit, Seattle, Washington 98101, USA
    Pharmacogenet Genomics 18:535-43. 2008
    ..We conducted a population-based, case-control study at Group Health to determine whether common genetic variation in the CYP2J2, CYP2C8, and CYP2C9 genes was associated with the risk of myocardial infarction and ischemic stroke...
  46. pmc Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke
    Daniel A Enquobahrie
    Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA
    Am J Cardiol 101:1683-8. 2008
    ..77 to 0.99). No within-gene or gene-gene interaction was associated with MI or ischemic stroke risk. In conclusion, potential SNP-disease associations identified in the present study are novel and need further investigation...
  47. pmc Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke
    Lucia A Hindorff
    Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA
    Pharmacogenet Genomics 18:677-82. 2008
    ....
  48. ncbi request reprint Smoking status and risk for recurrent coronary events after myocardial infarction
    Thomas D Rea
    University of Washington, Cardiovascular Health Research Unit, Metropolitan Park, East Tower, 1730 Minor Avenue, Suite 1360, Seattle, WA 98101, USA
    Ann Intern Med 137:494-500. 2002
    ..Questions remain about the importance of smoking and smoking cessation after incident myocardial infarction...
  49. ncbi request reprint Hormone replacement therapy, prothrombotic mutations, and the risk of incident nonfatal ischemic stroke in postmenopausal women
    Rozenn N Lemaitre
    Arterioscler Thromb Vasc Biol 22:1051-2. 2002
  50. ncbi request reprint Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension
    Bruce M Psaty
    Cardiovascular Health Research Unit, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
    JAMA 287:1680-9. 2002
    ..Whether this genetic variant modifies the effect of diuretic therapy on the incidence of myocardial infarction (MI) and stroke is unknown...
  51. ncbi request reprint Time trends in high blood pressure control and the use of antihypertensive medications in older adults: the Cardiovascular Health Study
    Bruce M Psaty
    Cardiovascular Health Research Unit, Department of Medicine, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
    Arch Intern Med 162:2325-32. 2002
    ..Control of high blood pressure (BP) in older adults is an important part of public health efforts at prevention...
  52. ncbi request reprint Longitudinal association between depressive symptoms and incident type 2 diabetes mellitus in older adults: the cardiovascular health study
    Mercedes R Carnethon
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA
    Arch Intern Med 167:802-7. 2007
    ..Prospective studies indicate that a single self-report of high depressive symptoms is associated with an increased risk of developing type 2 diabetes mellitus...
  53. ncbi request reprint Amount of leisure-time physical activity and risk of nonfatal myocardial infarction
    Gina S Lovasi
    Columbia University, Institute for Social and Economic Research and Policy, New York, NY 10027, USA
    Ann Epidemiol 17:410-6. 2007
    ..To investigate the shape of the relation between amount of leisure-time physical activity (LTPA) and myocardial infarction (MI) risk...
  54. ncbi request reprint Risk of congestive heart failure in an elderly population treated with peripheral alpha-1 antagonists
    Chris L Bryson
    VA Puget Sound Health Services Research and Development, VAMC, Seattle, Washington 98108, USA
    J Am Geriatr Soc 52:1648-54. 2004
    ....
  55. ncbi request reprint Serum lipid levels and the risk of venous thrombosis
    Carine J M Doggen
    Department of Epidemiology, University of Washington, Seattle, USA
    Arterioscler Thromb Vasc Biol 24:1970-5. 2004
    ..Lipids, through effects on the coagulation and fibrinolytic systems, may contribute to the development of venous thrombosis. This association has been investigated in a few studies, with conflicting results...
  56. ncbi request reprint The association of fasting glucose levels with congestive heart failure in diabetic adults > or =65 years: the Cardiovascular Health Study
    Joshua I Barzilay
    Kaiser Permanente of Georgia and the Division of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA
    J Am Coll Cardiol 43:2236-41. 2004
    ..The purpose of this study was to determine if fasting glucose levels are an independent risk factor for congestive heart failure (CHF) in elderly individuals with diabetes mellitus (DM) with or without coronary heart disease (CHD)...
  57. ncbi request reprint Risk of myocardial infarction attributable to elevated levels of total cholesterol among hypertensives
    Nicole L Glazer
    Department of Epidemiology, University of Washington, Seattle, Washington 98101, USA
    Am J Hypertens 18:759-66. 2005
    ....
  58. ncbi request reprint Congestive heart failure incidence and prognosis: case identification using central adjudication versus hospital discharge diagnoses
    Gina D Schellenbaum
    Department of Epidemiology, University of Washington, Seattle, WA 98101, and Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN, USA
    Ann Epidemiol 16:115-22. 2006
    ..We compared hospitalized congestive heart failure (CHF) incidence and prognosis estimates using hospital discharge diagnoses or central adjudication...
  59. ncbi request reprint Association of beta-blocker use with mortality among patients with congestive heart failure in the Cardiovascular Health Study (CHS)
    Jeannie D Chan
    Department of Pharmacy, University of Washington, Seattle, Washington, USA
    Am Heart J 150:464-70. 2005
    ..This study assessed the association between beta-blocker therapy and mortality among community-dwelling older adults with CHF...
  60. ncbi request reprint Weight loss, muscle strength, and angiotensin-converting enzyme inhibitors in older adults with congestive heart failure or hypertension
    Gina D Schellenbaum
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    J Am Geriatr Soc 53:1996-2000. 2005
    ..To determine whether angiotensin-converting enzyme (ACE) inhibitor use may be associated with weight maintenance and sustained muscle strength (measured by grip strength) in older adults...
  61. ncbi request reprint Common genetic variation in the prothrombin gene, hormone therapy, and incident nonfatal myocardial infarction in postmenopausal women
    Lucia A Hindorff
    Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98101, USA
    Am J Epidemiol 163:600-7. 2006
    ..These preliminary results suggest that common genetic variants in the prothrombin gene or other variants in linkage disequilibrium are associated with myocardial infarction in postmenopausal women...
  62. ncbi request reprint Esterified estrogen and conjugated equine estrogen and the risk of incident myocardial infarction and stroke
    Rozenn N Lemaitre
    Cardiovascular Health Research Unit, Department of Medicine, University of Washington, and Center for Health Studies, Group Health Cooperative, Seattle 98101 1448, USA
    Arch Intern Med 166:399-404. 2006
    ..The association of these end points with the use of esterified estrogen (EE) is unknown...
  63. ncbi request reprint Angiotensinogen Met235Thr polymorphism, angiotensin-converting enzyme inhibitor therapy, and the risk of nonfatal stroke or myocardial infarction in hypertensive patients
    Joshua C Bis
    Cardiovascular Health Research Unit, Department of Epidemiology, University of Washington, Seattle, Washington 98101, USA
    Am J Hypertens 16:1011-7. 2003
    ....
  64. ncbi request reprint Hormone replacement therapy and the risk of incident congestive heart failure: the Cardiovascular Health Study
    Thomas D Rea
    Cardiovascular Health Research Unit, University of Washington, Metropolitan Park, East Tower, 1730 Minor Avenue, Seattle, WA 98101, USA
    J Womens Health (Larchmt) 12:341-50. 2003
    ..Hormone replacement therapy (HRT) affects several of the pathways that may be important in the development of CHF. We hypothesized that HRT would be associated with a decreased risk of incident CHF...
  65. ncbi request reprint Genetic variants of coagulation factor XIII, postmenopausal estrogen therapy, and risk of nonfatal myocardial infarction
    Alexander P Reiner
    Cardiovascular Health Research Unit, Department of Epidemiology, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, WA 98101 1448, USA
    Blood 102:25-30. 2003
    ..03). If confirmed, these findings may permit a better assessment of the cardiovascular risks and benefits associated with postmenopausal estrogen therapy...
  66. pmc Mortality in pharmacologically treated older adults with diabetes: the Cardiovascular Health Study, 1989-2001
    Richard A Kronmal
    Collaborative Heath Studies Coordinating Center and Department of Biostatistics, University of Washington, Seattle, Washington, United States of America
    PLoS Med 3:e400. 2006
    ..It is uncertain, however, whether excess DM mortality continues beyond age 75 years, is related to type of hypoglycemic therapy, and whether women continue to be disproportionately affected by DM into older age...
  67. ncbi request reprint Risk of new-onset atrial fibrillation in relation to body mass index
    Sascha Dublin
    Veterans Affairs Puget Sound Health Care System, Seattle, WA 98101, USA
    Arch Intern Med 166:2322-8. 2006
    ..It is also unknown to what extent cardiovascular risk factors may mediate this association...
  68. ncbi request reprint Newly detected atrial fibrillation and compliance with antithrombotic guidelines
    Nicole L Glazer
    Cardiovascular Health Research Unit and Department of Epidemiology, University of Washington, 1730 Minor Avenue, Seattle, WA 98101, USA
    Arch Intern Med 167:246-52. 2007
    ..Our objective was to assess compliance with antithrombotic guidelines and to identify patient characteristics associated with warfarin use...
  69. pmc Evaluating options for measurement of neighborhood socioeconomic context: evidence from a myocardial infarction case-control study
    Gina S Lovasi
    Institute of Social and Economic Research and Policy, Columbia University, 820 IAB, MC 3355, 420 W 118th Street, New York, NY 10027, USA
    Health Place 14:453-67. 2008
    ..Although we confirmed the association between neighborhood socioeconomic measures and risk of MI, we did not find these associations sensitive to neighborhood definition...
  70. ncbi request reprint Mental stress-induced ischemia and all-cause mortality in patients with coronary artery disease
    Gina D Schellenbaum
    Circulation 106:e183-4; author reply e183-4. 2002

Research Grants9

  1. Clotting genetic variant, hormones and venous thrombosis
    Nicholas Smith; Fiscal Year: 2004
    ....
  2. Clotting genetic variant, hormones and venous thrombosis
    Nicholas Smith; Fiscal Year: 2005
    ....
  3. Clotting genetic variant, hormones and venous thrombosis
    Nicholas Smith; Fiscal Year: 2006
    ....
  4. Clotting genetic variant, hormones and venous thrombosis
    Nicholas Smith; Fiscal Year: 2007
    ....
  5. Pharmacologic and pharmacogenetic associations with recurrent venous thrombosis
    Nicholas Smith; Fiscal Year: 2009
    ..abstract_text> ..
  6. Estrogens and pharmacogenetic risks of venous thrombosis in postmenopausal women
    Nicholas Smith; Fiscal Year: 2009
    ..We propose an extension of our population-based, case-control study in post-menopausal women to examine risks of venous thrombosis associated with oral estradiol and other estrogens. ..
  7. Pharmacologic and pharmacogenetic associations with recurrent venous thrombosis
    Nicholas L Smith; Fiscal Year: 2010
    ..abstract_text> ..
  8. Estrogens and pharmacogenetic risks of venous thrombosis in postmenopausal women
    Nicholas L Smith; Fiscal Year: 2010
    ..We propose an extension of our population-based, case-control study in post-menopausal women to examine risks of venous thrombosis associated with oral estradiol and other estrogens. ..