Mary Alice Smith

Summary

Affiliation: University of Georgia
Country: USA

Publications

  1. pmc Nonhuman primate model for Listeria monocytogenes-induced stillbirths
    Mary Alice Smith
    Department of Environmental Health Science, University of Georgia, Athens, Georgia 30602, USA
    Infect Immun 71:1574-9. 2003
  2. pmc Dose-response model for Listeria monocytogenes-induced stillbirths in nonhuman primates
    Mary Alice Smith
    Department of Environmental Health Science, College of Public Health, University of Georgia, 206 Environmental Health Science Bldg, Athens, GA 30602 2102, USA
    Infect Immun 76:726-31. 2008
  3. ncbi request reprint Comparison of virulence of three strains of Cronobacter sakazakii in neonatal CD-1 mice
    Arena N Richardson
    Department of Environmental Health Science, 206 Environmental Health Science Building, University of Georgia, Athens, Georgia 30602 2102, USA
    J Food Prot 73:849-54. 2010
  4. ncbi request reprint Comparison of Listeria monocytogenes virulence in a mouse model
    Kazue Takeuchi
    Center for Food Safety, University of Georgia, Griffin 30223, USA
    J Food Prot 69:842-6. 2006
  5. doi request reprint Immunological and pathological changes in the placenta during infection with Listeria monocytogenes in pregnant guinea pigs
    Elizabeth Ann Irvin
    Interdisciplinary Toxicology Program, Department of Environmental Health Science, University of Georgia, Athens, GA 30602, USA
    Reprod Toxicol 26:151-5. 2008
  6. doi request reprint Risk of fetal mortality after exposure to Listeria monocytogenes based on dose-response data from pregnant guinea pigs and primates
    Denita Williams
    Center for Food Safety and Environmental Health Science Department, University of Georgia, Athens, GA 30602, USA
    Risk Anal 29:1495-505. 2009
  7. doi request reprint Susceptibility to Cronobacter sakazakii decreases with increasing age in neonatal CD-1 mice
    Arena N Richardson
    Department of Environmental Health Science, 206 Environmental Health Science Building, University of Georgia, Athens, GA 30602 2102, USA
    J Food Prot 75:884-8. 2012
  8. doi request reprint Time course of fetal tissue invasion by Listeria monocytogenes following an oral inoculation in pregnant guinea pigs
    Denita Williams
    Department of Environmental Health Science, University of Georgia, Athens, Georgia 30602, USA
    J Food Prot 74:248-53. 2011
  9. ncbi request reprint Neonatal mice as models for Cronobacter sakazakii infection in infants
    Arena N Richardson
    Department of Environmental Health Science, University of Georgia, Athens, Georgia 30602 2102, USA
    J Food Prot 72:2363-7. 2009
  10. doi request reprint Listeria monocytogenes infection in pregnant guinea pigs is associated with maternal liver necrosis, a decrease in maternal serum TNF-alpha concentrations, and an increase in placental apoptosis
    Elizabeth Ann Irvin
    Interdisciplinary Toxicology Program, Department of Environmental Health Science, University of Georgia, Athens, GA 30606, USA
    Reprod Toxicol 26:123-9. 2008

Collaborators

Detail Information

Publications19

  1. pmc Nonhuman primate model for Listeria monocytogenes-induced stillbirths
    Mary Alice Smith
    Department of Environmental Health Science, University of Georgia, Athens, Georgia 30602, USA
    Infect Immun 71:1574-9. 2003
    ..monocytogenes had survived and had probably colonized the gastrointestinal tract. Antibodies and antigen-specific lymphocyte proliferation against Listeria increased in animals that had stillbirths...
  2. pmc Dose-response model for Listeria monocytogenes-induced stillbirths in nonhuman primates
    Mary Alice Smith
    Department of Environmental Health Science, College of Public Health, University of Georgia, 206 Environmental Health Science Bldg, Athens, GA 30602 2102, USA
    Infect Immun 76:726-31. 2008
    ..This information will aid in risk assessment, assist policy makers, and provide a model for mechanistic studies of L. monocytogenes-induced stillbirths...
  3. ncbi request reprint Comparison of virulence of three strains of Cronobacter sakazakii in neonatal CD-1 mice
    Arena N Richardson
    Department of Environmental Health Science, 206 Environmental Health Science Building, University of Georgia, Athens, Georgia 30602 2102, USA
    J Food Prot 73:849-54. 2010
    ..6%) than MNW2 (1.2%) or 3290 (0.6%). Our findings suggest that invasiveness does not necessarily correlate with mortality among different strains of C. sakazakii, and the clinical isolates are more virulent than the food isolate...
  4. ncbi request reprint Comparison of Listeria monocytogenes virulence in a mouse model
    Kazue Takeuchi
    Center for Food Safety, University of Georgia, Griffin 30223, USA
    J Food Prot 69:842-6. 2006
    ..The lack of strain differences may reflect the limitation of the mouse model and suggests the importance of using various models to evaluate the pathogenicity and virulence of L. monocytogenes strains...
  5. doi request reprint Immunological and pathological changes in the placenta during infection with Listeria monocytogenes in pregnant guinea pigs
    Elizabeth Ann Irvin
    Interdisciplinary Toxicology Program, Department of Environmental Health Science, University of Georgia, Athens, GA 30602, USA
    Reprod Toxicol 26:151-5. 2008
    ..In conclusion, inflammatory cytokine mRNA expression is altered and apoptosis is increased in the placenta after treatment with L. monocytogenes, and these changes may contribute to fetal death...
  6. doi request reprint Risk of fetal mortality after exposure to Listeria monocytogenes based on dose-response data from pregnant guinea pigs and primates
    Denita Williams
    Center for Food Safety and Environmental Health Science Department, University of Georgia, Athens, GA 30602, USA
    Risk Anal 29:1495-505. 2009
    ..9 x 10(-1) compared to the FDA/USDA/CDC (fig. IV-12) predicted rate of 1.3 x 10(-7). Based on the guinea pig and primate models, the mortality rate calculated by the FDA/USDA/CDC is underestimated for this susceptible population...
  7. doi request reprint Susceptibility to Cronobacter sakazakii decreases with increasing age in neonatal CD-1 mice
    Arena N Richardson
    Department of Environmental Health Science, 206 Environmental Health Science Building, University of Georgia, Athens, GA 30602 2102, USA
    J Food Prot 75:884-8. 2012
    ..Mortality was observed only in neonates treated at PND 1.5. In conclusion, neonatal mice had a time-dependent susceptibility to C. sakazakii infection, with resistance increasing with increasing age...
  8. doi request reprint Time course of fetal tissue invasion by Listeria monocytogenes following an oral inoculation in pregnant guinea pigs
    Denita Williams
    Department of Environmental Health Science, University of Georgia, Athens, Georgia 30602, USA
    J Food Prot 74:248-53. 2011
    ..001) and brain (P<0.001) at the highest dose of 10(8) CFU, but at the lowest dose of 10(4) CFU culture was significantly more sensitive with maternal spleen (P=0.04)...
  9. ncbi request reprint Neonatal mice as models for Cronobacter sakazakii infection in infants
    Arena N Richardson
    Department of Environmental Health Science, University of Georgia, Athens, Georgia 30602 2102, USA
    J Food Prot 72:2363-7. 2009
    ..C. sakazakii was isolated from brains, livers, and ceca in all three mouse strains. The CD-1 mouse strain was the most susceptible of the three, with the lowest infectious dose (10(2) CFU) and the lowest lethal dose (also 10(2) CFU)...
  10. doi request reprint Listeria monocytogenes infection in pregnant guinea pigs is associated with maternal liver necrosis, a decrease in maternal serum TNF-alpha concentrations, and an increase in placental apoptosis
    Elizabeth Ann Irvin
    Interdisciplinary Toxicology Program, Department of Environmental Health Science, University of Georgia, Athens, GA 30606, USA
    Reprod Toxicol 26:123-9. 2008
    ..In conclusion, increases in premature delivery, maternal hepatic effects and placental apoptosis along with a decrease in TNF-alpha concentrations were associated with L. monocytogenes infection in pregnant guinea pigs...
  11. ncbi request reprint Perfluorooctanoic acid and perfluorononanoic acid in fetal and neonatal mice following in utero exposure to 8-2 fluorotelomer alcohol
    W Matthew Henderson
    Interdisciplinary Toxicology Program, College of Public Health, University of Georgia, Athens, Georgia 30602, USA
    Toxicol Sci 95:452-61. 2007
    ..In conclusion, exposure of neonates to PFOA and PFNA occurs both pre- and postnatally following maternal 8-2 FTOH exposure on GD8...
  12. ncbi request reprint Pathogenicity of food and clinical Listeria monocytogenes isolates in a mouse bioassay
    Kazue Takeuchi
    Center for Food Safety, University of Georgia, 1109 Experiment Street, Griffin, Georgia 30223, USA
    J Food Prot 66:2362-6. 2003
    ..We have identified several L. monocytogenes strains with reduced virulence levels. Further characterization of such isolates may aid in understanding factors affecting the variation in virulence among strains...
  13. doi request reprint Metabolomic response of human embryonic stem cell-derived germ-like cells after exposure to steroid hormones
    Franklin D West
    Department of Animal and Dairy Science, University of Georgia, Athens, Georgia 30603, USA
    Toxicol Sci 129:9-20. 2012
    ....
  14. ncbi request reprint Quantification of fluorotelomer-based chemicals in mammalian matrices by monitoring perfluoroalkyl chain fragments with GC/MS
    W Matthew Henderson
    National Exposure Research Laboratory, U S Environmental Protection Agency, Athens, GA 30605, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 846:155-61. 2007
    ....
  15. ncbi request reprint Dose-response for retinoic acid-induced forelimb malformations and cleft palate: a comparison of computerized image analysis and visual inspection
    Jerry L Campbell
    Department of Environmental Health Science, University of Georgia, Athens, Georgia, USA
    Birth Defects Res B Dev Reprod Toxicol 71:289-95. 2004
    ....
  16. ncbi request reprint A processing plant persistent strain of Listeria monocytogenes crosses the fetoplacental barrier in a pregnant guinea pig model
    Anne Jensen
    Department of Seafood Research, National Institute of Aquatic Resources, Technical University of Denmark, Søltofts Plads Building 221, DK 2800 Kgs Lyngby, Denmark
    J Food Prot 71:1028-34. 2008
    ..Furthermore, we demonstrate that although information can be gained from model virulence assays, assessment of the virulence potential of a strain may require more complex hosts...
  17. pmc Porphyromonas gingivalis infection during pregnancy increases maternal tumor necrosis factor alpha, suppresses maternal interleukin-10, and enhances fetal growth restriction and resorption in mice
    Dongming Lin
    Center for Oral and Systemic Diseases, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Infect Immun 71:5156-62. 2003
    ..These data demonstrate that P. gingivalis-induced murine FGR is associated with systemic dissemination of the organism and activated maternal immune and inflammatory responses...
  18. ncbi request reprint Campylobacter rectus mediates growth restriction in pregnant mice
    Alvin Yeo
    Center for Oral and Systemic Diseases, Department of Periodontology, University of North Carolina, School of Dentistry, Chapel Hill, 27599, USA
    J Periodontol 76:551-7. 2005
    ..Our objective was to determine the effects of Campylobacter rectus (C. rectus) infection on pregnancy outcomes in a mouse model...
  19. pmc Porphyromonas gingivalis infection in pregnant mice is associated with placental dissemination, an increase in the placental Th1/Th2 cytokine ratio, and fetal growth restriction
    Dongming Lin
    Center for Oral and Systemic Diseases, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Infect Immun 71:5163-8. 2003
    ..gingivalis that results in growth restriction of the targeted fetus, which is associated with a shift in the placental Th1/Th2 cytokine balance...