Kenneth Smith

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Cost-effectiveness of newer treatment strategies for influenza
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, and the Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Med 113:300-7. 2002
  2. doi request reprint Economic evaluation of standing order programs for pneumococcal vaccination of hospitalized elderly patients
    Donald B Middleton
    Department of Family Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15232, USA
    Infect Control Hosp Epidemiol 29:385-94. 2008
  3. pmc Cost comparisons between home- and clinic-based testing for sexually transmitted diseases in high-risk young women
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Infect Dis Obstet Gynecol 2007:62467. 2007
  4. doi request reprint Alternative strategies for adult pneumococcal polysaccharide vaccination: a cost-effectiveness analysis
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States
    Vaccine 26:1420-31. 2008
  5. ncbi request reprint Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategies
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 34:960-6. 2007
  6. pmc Cost-effectiveness of procalcitonin-guided antibiotic use in community acquired pneumonia
    Kenneth J Smith
    Department of Medicine, University of Pittsburgh School of Medicine, 200 Meyran Ave, Suite 200, Pittsburgh, PA, 15213, USA
    J Gen Intern Med 28:1157-64. 2013
  7. pmc Cost-effectiveness of pneumococcal conjugate vaccination in immunocompromised adults
    Kenneth J Smith
    University of Pittsburgh School of Medicine, Pittsburgh, PA, United States Electronic address
    Vaccine 31:3950-6. 2013
  8. ncbi request reprint Information primary care physicians want to receive about their hospitalized patients
    Kenneth J Smith
    Department of Medicine, University of Pittsburgh, PA 15213, USA
    Fam Med 44:425-30. 2012
  9. doi request reprint Cost-effectiveness of adult vaccination strategies using pneumococcal conjugate vaccine compared with pneumococcal polysaccharide vaccine
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Management, University of Pittsburgh School of Medicine, 200 Meyran Ave, Ste 200, Pittsburgh, PA 15213, USA
    JAMA 307:804-12. 2012
  10. ncbi request reprint Quality of life utilities for pelvic inflammatory disease health states
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 35:307-11. 2008

Research Grants

Detail Information

Publications41

  1. ncbi request reprint Cost-effectiveness of newer treatment strategies for influenza
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, and the Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Med 113:300-7. 2002
    ..Recent advances in the diagnosis and treatment of influenza, such as rapid testing and neuraminidase inhibitor therapy, are available, but their place in clinical practice and their cost-effectiveness have not been determined...
  2. doi request reprint Economic evaluation of standing order programs for pneumococcal vaccination of hospitalized elderly patients
    Donald B Middleton
    Department of Family Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15232, USA
    Infect Control Hosp Epidemiol 29:385-94. 2008
    ..The purpose of this study was to estimate the cost-effectiveness of SOPs for pneumococcal polysaccharide vaccine (PPV) vaccination for patients 65 years of age or older in 2 types of hospital...
  3. pmc Cost comparisons between home- and clinic-based testing for sexually transmitted diseases in high-risk young women
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Infect Dis Obstet Gynecol 2007:62467. 2007
    ..A home testing program could be cost saving, depending on whether changes in clinic testing frequency occur when home testing is available...
  4. doi request reprint Alternative strategies for adult pneumococcal polysaccharide vaccination: a cost-effectiveness analysis
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States
    Vaccine 26:1420-31. 2008
    ..PPV at ages 50/65 may be clinically and, depending on cost-effectiveness criterion used, economically favored over present vaccination recommendations...
  5. ncbi request reprint Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategies
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 34:960-6. 2007
    ..Effectiveness differences between outpatient pelvic inflammatory disease (PID) treatment regimens are uncertain, but significant differences in cost exist...
  6. pmc Cost-effectiveness of procalcitonin-guided antibiotic use in community acquired pneumonia
    Kenneth J Smith
    Department of Medicine, University of Pittsburgh School of Medicine, 200 Meyran Ave, Suite 200, Pittsburgh, PA, 15213, USA
    J Gen Intern Med 28:1157-64. 2013
    ....
  7. pmc Cost-effectiveness of pneumococcal conjugate vaccination in immunocompromised adults
    Kenneth J Smith
    University of Pittsburgh School of Medicine, Pittsburgh, PA, United States Electronic address
    Vaccine 31:3950-6. 2013
    ..This analysis estimates the cost-effectiveness of pneumococcal vaccination strategies in HIV-infected individuals and in the broader immunocompromised adult group...
  8. ncbi request reprint Information primary care physicians want to receive about their hospitalized patients
    Kenneth J Smith
    Department of Medicine, University of Pittsburgh, PA 15213, USA
    Fam Med 44:425-30. 2012
    ..It is unclear what hospital information PCPs would find most valuable in their patients' continuing care, as is how and when they would prefer to receive such information...
  9. doi request reprint Cost-effectiveness of adult vaccination strategies using pneumococcal conjugate vaccine compared with pneumococcal polysaccharide vaccine
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Management, University of Pittsburgh School of Medicine, 200 Meyran Ave, Ste 200, Pittsburgh, PA 15213, USA
    JAMA 307:804-12. 2012
    ..The cost-effectiveness of 13-valent pneumococcal conjugate vaccine (PCV13) compared with 23-valent pneumococcal polysaccharide vaccine (PPSV23) among US adults is unclear...
  10. ncbi request reprint Quality of life utilities for pelvic inflammatory disease health states
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 35:307-11. 2008
    ..Utilities for PID could have important implications on the cost-effectiveness of interventions to prevent and manage this disease...
  11. ncbi request reprint Time from sexually transmitted infection acquisition to pelvic inflammatory disease development: influence on the cost-effectiveness of different screening intervals
    Kenneth J Smith
    School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Value Health 10:358-66. 2007
    ..Nevertheless, the time from STI acquisition to PID development, possibly an important factor to consider in screening interval choice, is unknown and its influence on the effectiveness and cost-effectiveness of screening is unclear...
  12. ncbi request reprint Sequential medication strategies for postherpetic neuralgia: a cost-effectiveness analysis
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Pain 8:396-404. 2007
    ..This decision analysis-based synthesis of effectiveness and cost data found that recommended treatment algorithms are also economically reasonable...
  13. ncbi request reprint Teaching medical decision modeling: a qualitative description of student errors and curriculum responses
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Med Decis Making 26:583-8. 2006
    ..Novice medical decision modelers are prone to errors. The purpose of this article is to describe the common errors committed by decision modeling students and the changes made to a structured decision modeling project course in response...
  14. ncbi request reprint Hospitalization for pelvic inflammatory disease: a cost-effectiveness analysis
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 34:108-12. 2007
    ..Nulliparous women are frequently hospitalized for treatment of pelvic inflammatory disease (PID)...
  15. pmc Cost-effectiveness of pneumococcal polysaccharide vaccine among healthcare workers during an influenza pandemic
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Manag Care 16:200-6. 2010
    ..To assess the usefulness and cost-effectiveness of pneumococcal polysaccharide vaccine (PPV) among healthcare workers compared with nonuse of PPV during an influenza pandemic...
  16. doi request reprint Age, revaccination, and tolerance effects on pneumococcal vaccination strategies in the elderly: a cost-effectiveness analysis
    Kenneth J Smith
    University of Pittsburgh, Pittsburgh, PA, USA
    Vaccine 27:3159-64. 2009
    ..Revaccination strategies for the elderly are less cost-effective, particularly when prior vaccination and vaccine tolerance are considered...
  17. pmc Economics of influenza vaccine administration timing for children
    Bruce Y Lee
    Public Health Computation and Operations Research PHICOR Group, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Manag Care 16:e75-e85. 2010
    ..To determine how much should be invested each year to encourage and operationalize the administration of influenza vaccine to children before November and how late the vaccine should be offered each year...
  18. doi request reprint Retropubic and transobturator midurethral slings: a decision analysis to compare outcomes including efficacy and complications
    Jonathan P Shepherd
    Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Pittsburgh Medical Center, Magee Women s Hospital, Pittsburgh, PA, USA
    Int Urogynecol J 21:787-93. 2010
    ..The objective of this paper is to compare retropubic (RP) and transobturator (TO) midurethral slings using decision analysis techniques...
  19. pmc The cost-effectiveness of community-based screening for oral cancer in high-risk males in the United States: a Markov decision analysis approach
    Raj C Dedhia
    Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15203, USA
    Laryngoscope 121:952-60. 2011
    ....
  20. doi request reprint A cost-effectiveness analysis of coagulation testing prior to tonsillectomy and adenoidectomy in children
    James D Cooper
    Division of Hematology Oncology BMT, Department of Pediatrics, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA
    Pediatr Blood Cancer 55:1153-9. 2010
    ..Studies of pre-operative screening have had conflicting results. A decision analysis model was constructed to address the costs and health outcome states of pre-operative screening strategies in children...
  21. ncbi request reprint Oral anticoagulation strategies after a first idiopathic venous thromboembolic event
    Drahomir Aujesky
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Am J Med 118:625-35. 2005
    ..We used decision analysis to evaluate clinical and economic outcomes of different anticoagulation strategies with warfarin...
  22. pmc Screening cardiac surgery patients for MRSA: an economic computer model
    Bruce Y Lee
    Section of Decision Sciences and Clinical Systems Modeling, Department of Biomedical Informatics, University of Pittsburgh, 200 Meyran Ave, Ste 200, Pittsburgh, PA 15213, USA
    Am J Manag Care 16:e163-73. 2010
    ..To estimate the economic value of preoperative methicillin-resistant Staphylococcus aureus (MRSA) screening and decolonization for cardiac surgery patients...
  23. doi request reprint Cost-utility analysis of von Willebrand disease screening in adolescents with menorrhagia
    Robert Francis Sidonio
    Division of Pediatric Hematology Oncology, Children s Hospital of Pittsburgh University of Pittsburgh Medical Center, Pittsburgh, PA 15201, USA
    J Pediatr 157:456-60, 460.e1. 2010
    ..To construct a decision analysis model to evaluate the cost utility of von Willebrand disease (VWD) testing in adolescents with menorrhagia...
  24. pmc Economics of employer-sponsored workplace vaccination to prevent pandemic and seasonal influenza
    Bruce Y Lee
    Applied Modeling, Public Health Computational and Operations Research, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Vaccine 28:5952-9. 2010
    ....
  25. ncbi request reprint Cost-effectiveness of low-molecular-weight heparin for secondary prophylaxis of cancer-related venous thromboembolism
    Drahomir Aujesky
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Thromb Haemost 93:592-9. 2005
    ..However, because of the substantial pharmacy costs of extended low-molecular-weight heparin prophylaxis in the US, this treatment is relatively expensive compared with warfarin...
  26. pmc Cost-effectiveness analysis of efforts to reduce risk of type 2 diabetes and cardiovascular disease in southwestern Pennsylvania, 2005-2007
    Kenneth J Smith
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Prev Chronic Dis 7:A109. 2010
    ..We assessed the cost-effectiveness of a community-based, modified Diabetes Prevention Program (DPP) designed to reduce risk factors for type 2 diabetes and cardiovascular disease...
  27. ncbi request reprint Should female relatives of factor V Leiden carriers be screened prior to oral contraceptive use? A cost-effectiveness analysis
    Kenneth J Smith
    Medicine Hematology Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 4306, USA
    Thromb Haemost 100:447-52. 2008
    ..In conclusion, screening, counselling and prophylactic AC during high-risk periods in female relatives of FVL carriers is an economically favourable strategy...
  28. ncbi request reprint Cost-effectiveness of low-molecular-weight heparin for treatment of pulmonary embolism
    Drahomir Aujesky
    Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, PA, USA
    Chest 128:1601-10. 2005
    ..Low-molecular-weight heparin (LMWH) appears to be safe and effective for treating pulmonary embolism (PE), but its cost-effectiveness has not been assessed...
  29. ncbi request reprint A cost-utility analysis of treatment for acute childhood idiopathic thrombocytopenic purpura (ITP)
    Sarah H O'Brien
    Pediatric Hematology Oncology, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Pediatr Blood Cancer 48:173-80. 2007
    ..The primary objective in the treatment of acute pediatric idiopathic thrombocytopenic purpura (ITP) is to rapidly increase the platelet count...
  30. ncbi request reprint Prediction of pelvic inflammatory disease among young, single, sexually active women
    Roberta B Ness
    Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA
    Sex Transm Dis 33:137-42. 2006
    ..To assess prediction strategies for pelvic inflammatory disease (PID)...
  31. pmc The timing of influenza vaccination for older adults (65 years and older)
    Bruce Y Lee
    Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Vaccine 27:7110-5. 2009
    ..50 per patient) to vaccinate in October. Our results also suggest that vaccination is still cost-effective through the end of February...
  32. pmc Should vascular surgery patients be screened preoperatively for methicillin-resistant Staphylococcus aureus?
    Bruce Y Lee
    Section of Decision Sciences and Clinical Systems Modeling, Department of Biomedical Informatics, School of Medicine, and Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Infect Control Hosp Epidemiol 30:1158-65. 2009
    ..Testing all vascular surgery patients preoperatively for MRSA and attempting to decolonize those who have positive results may be a strategy to prevent MRSA infection. The economic value of such a strategy has not yet been determined...
  33. doi request reprint Prophylactic antibiotics to prevent urinary tract infection during clean intermittent self-catheterization (CISC) for management of voiding dysfunction after prolapse and incontinence surgery: a decision analysis
    Gary Sutkin
    Division of Urogynecology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Hospital, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA 15213, USA
    Int Urogynecol J Pelvic Floor Dysfunct 20:933-8. 2009
    ..The objective of this study is to estimate efficacy of prophylactic antibiotics in UTI prevention during CISC for postoperative voiding dysfunction after prolapse/incontinence surgery...
  34. pmc Universal methicillin-resistant Staphylococcus aureus (MRSA) surveillance for adults at hospital admission: an economic model and analysis
    Bruce Y Lee
    Section of Decision Sciences and Clinical Systems Modeling, Veterans Affairs Pittsburgh Health Care System, Pittsburgh, Pennsylvania, USA
    Infect Control Hosp Epidemiol 31:598-606. 2010
    ..Although some have recommended universal surveillance for MRSA at hospital admission to identify and to isolate MRSA-colonized patients, there is a need for formal economic studies to determine the cost-effectiveness of such a strategy...
  35. pmc The potential economic value of a Staphylococcus aureus vaccine for neonates
    Bruce Y Lee
    Applied Modeling, Public Health Computational and Operations Research PHICOR, Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Vaccine 28:4653-60. 2010
    ..aureus vaccine for the neonatal population would be strongly cost-effective (and in many situations dominant) over a wide range of vaccine efficacies (down to 10%) for vaccine costs (<or=$500), and S. aureus attack rates (>or=1%)...
  36. doi request reprint Direct paramedic transport of acute myocardial infarction patients to percutaneous coronary intervention centers: a decision analysis
    Henry E Wang
    Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Ann Emerg Med 53:233-240. 2009
    ....
  37. ncbi request reprint Contraceptive effectiveness of immediate compared with delayed insertion of intrauterine devices after abortion: a decision analysis
    Matthew F Reeves
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine and the Magee Womens Research Institute, Pittsburgh, Pennsylvania 15213 3180, USA
    Obstet Gynecol 109:1286-94. 2007
    ..To model rates of pregnancy and repeat abortion among women choosing intrauterine contraception after an abortion when the intrauterine device (IUD) is inserted immediately after the procedure or at a follow-up visit...
  38. ncbi request reprint Optimizing the timing of chemotherapy for mobilizing autologous blood hematopoietic progenitor cells
    Michelle L Hicks
    Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA
    Transfusion 47:629-35. 2007
    ..Postchemotherapy mobilization results were reviewed in patients undergoing apheresis before planned autologous hematopoietic progenitor cell (HPC) transplantation to improve the timing of collection procedures...
  39. ncbi request reprint Cost-effectiveness of a vaccine to prevent herpes zoster and postherpetic neuralgia in older adults
    Michael B Rothberg
    Division of General Medicine and Geriatrics, Department of Medicine, Baystate Medical Center, Springfield, MA 01199, USA
    Clin Infect Dis 44:1280-8. 2007
    ..A vaccine to prevent herpes zoster was recently approved by the United States Food and Drug Administration. We sought to determine the cost-effectiveness of this vaccine for different age groups...
  40. pmc Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?
    Christina Marik
    Centre for Brain Research, Medical University of Vienna, Austria
    Brain 130:2800-15. 2007
    ..The findings indicate that mechanisms associated with innate immunity may play a role in the formation of hypoxia-like demyelinating lesions in MS...
  41. ncbi request reprint Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide
    Paul A Felts
    Department of Neuroimmunology and Neuroinflammation Research Group, Guy s, King s and St Thomas School of Medicine, King s College London, London, UK
    Brain 128:1649-66. 2005
    ..2000), and we therefore suggest that LPS-induced demyelination may serve as the first experimental model available for the study of this type of multiple sclerosis lesion...

Research Grants4

  1. Alternative Strategies for Adult Pneumococcal Vaccination
    Kenneth J Smith; Fiscal Year: 2010
    ..This research will produce a mathematical model to assist pneumococcal vaccine policymaking, particularly in prioritizing and allocating resources to future research efforts. ..
  2. Optimal Strategies for PID Prevention and Management
    Kenneth Smith; Fiscal Year: 2007
    ..abstract_text> ..
  3. Alternative Strategies for Adult Pneumococcal Vaccination
    Kenneth Smith; Fiscal Year: 2009
    ..This research will produce a mathematical model to assist pneumococcal vaccine policymaking, particularly in prioritizing and allocating resources to future research efforts. ..