Research Topics
| Kenneth J SmithSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Cost-effectiveness of newer treatment strategies for influenzaKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, Division of General Internal Medicine, and the Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Am J Med 113:300-7. 2002..Recent advances in the diagnosis and treatment of influenza, such as rapid testing and neuraminidase inhibitor therapy, are available, but their place in clinical practice and their cost-effectiveness have not been determined...
The potential economic value of a Staphylococcus aureus vaccine for neonatesBruce Y Lee
Applied Modeling, Public Health Computational and Operations Research PHICOR, Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA 15213, USA
Vaccine 28:4653-60. 2010..aureus vaccine for the neonatal population would be strongly cost-effective (and in many situations dominant) over a wide range of vaccine efficacies (down to 10%) for vaccine costs (<or=$500), and S. aureus attack rates (>or=1%)...- Economics of employer-sponsored workplace vaccination to prevent pandemic and seasonal influenzaBruce Y Lee
Applied Modeling, Public Health Computational and Operations Research, University of Pittsburgh, Pittsburgh, PA 15213, USA
Vaccine 28:5952-9. 2010.... - Screening cardiac surgery patients for MRSA: an economic computer modelBruce Y Lee
Section of Decision Sciences and Clinical Systems Modeling, Department of Biomedical Informatics, University of Pittsburgh, 200 Meyran Ave, Ste 200, Pittsburgh, PA 15213, USA
Am J Manag Care 16:e163-73. 2010..To estimate the economic value of preoperative methicillin-resistant Staphylococcus aureus (MRSA) screening and decolonization for cardiac surgery patients... - Cost-effectiveness of pneumococcal polysaccharide vaccine among healthcare workers during an influenza pandemicKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Manag Care 16:200-6. 2010..To assess the usefulness and cost-effectiveness of pneumococcal polysaccharide vaccine (PPV) among healthcare workers compared with nonuse of PPV during an influenza pandemic... 
Anticoagulation in ambulatory cancer patients with no indication for prophylactic or therapeutic anticoagulation: a cost-effectiveness analysis from a U.S. perspectiveAllyson M Pishko
Department of Medicine, Division Hematology Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 4306, USA
Thromb Haemost 108:303-10. 2012..In conclusion, prophylactic LMWH given to decrease cancer-related mortality, with no conventional indication, appears economically reasonable if its suggested mortality benefit is confirmed in future trials...- Cost-effectiveness of adult vaccination strategies using pneumococcal conjugate vaccine compared with pneumococcal polysaccharide vaccineKenneth J Smith
Section of Decision Sciences and Clinical Systems Management, University of Pittsburgh School of Medicine, 200 Meyran Ave, Ste 200, Pittsburgh, PA 15213, USA
JAMA 307:804-12. 2012..The cost-effectiveness of 13-valent pneumococcal conjugate vaccine (PCV13) compared with 23-valent pneumococcal polysaccharide vaccine (PPSV23) among US adults is unclear... - The timing of influenza vaccination for older adults (65 years and older)Bruce Y Lee
Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Vaccine 27:7110-5. 2009..50 per patient) to vaccinate in October. Our results also suggest that vaccination is still cost-effective through the end of February... - Economic evaluation of standing order programs for pneumococcal vaccination of hospitalized elderly patientsDonald B Middleton
Department of Family Medicine, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15232, USA
Infect Control Hosp Epidemiol 29:385-94. 2008..The purpose of this study was to estimate the cost-effectiveness of SOPs for pneumococcal polysaccharide vaccine (PPV) vaccination for patients 65 years of age or older in 2 types of hospital... - Universal methicillin-resistant Staphylococcus aureus (MRSA) surveillance for adults at hospital admission: an economic model and analysisBruce Y Lee
Section of Decision Sciences and Clinical Systems Modeling, Veterans Affairs Pittsburgh Health Care System, Pittsburgh, Pennsylvania, USA
Infect Control Hosp Epidemiol 31:598-606. 2010..Although some have recommended universal surveillance for MRSA at hospital admission to identify and to isolate MRSA-colonized patients, there is a need for formal economic studies to determine the cost-effectiveness of such a strategy... - Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-oldsKenneth J Smith
University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
Vaccine 28:7620-5. 2010..Results were sensitive to shorter time horizons, favoring CDC recommendations. We found dual vaccination of all 50-year-olds economically reasonable. Shorter duration models may not fully account for PPV effectiveness... - Cost-effectiveness of low-molecular-weight heparin for secondary prophylaxis of cancer-related venous thromboembolismDrahomir Aujesky
Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
Thromb Haemost 93:592-9. 2005..However, because of the substantial pharmacy costs of extended low-molecular-weight heparin prophylaxis in the US, this treatment is relatively expensive compared with warfarin... - Age, revaccination, and tolerance effects on pneumococcal vaccination strategies in the elderly: a cost-effectiveness analysisKenneth J Smith
University of Pittsburgh, Pittsburgh, PA, USA
Vaccine 27:3159-64. 2009..Revaccination strategies for the elderly are less cost-effective, particularly when prior vaccination and vaccine tolerance are considered... - Cost-effectiveness of implementing the chronic care model for diabetes care in a military populationShihchen Kuo
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Diabetes Sci Technol 5:501-13. 2011..The CCM was implemented at U.S. Air Force Wilford Hall Medical Center through the Diabetes Outreach Clinic (DOC) in 2006, but its cost-effectiveness in this setting is unknown... - Quality of life utilities for pelvic inflammatory disease health statesKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 35:307-11. 2008..Utilities for PID could have important implications on the cost-effectiveness of interventions to prevent and manage this disease... - Economics of influenza vaccine administration timing for childrenBruce Y Lee
Public Health Computation and Operations Research PHICOR Group, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Manag Care 16:e75-e85. 2010..To determine how much should be invested each year to encourage and operationalize the administration of influenza vaccine to children before November and how late the vaccine should be offered each year... - Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategiesKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 34:960-6. 2007..Effectiveness differences between outpatient pelvic inflammatory disease (PID) treatment regimens are uncertain, but significant differences in cost exist... - Cost-effectiveness of low-molecular-weight heparin for treatment of pulmonary embolismDrahomir Aujesky
Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, PA, USA
Chest 128:1601-10. 2005..Low-molecular-weight heparin (LMWH) appears to be safe and effective for treating pulmonary embolism (PE), but its cost-effectiveness has not been assessed... - Modeling of cost effectiveness of pneumococcal conjugate vaccination strategies in U.S. older adultsKenneth J Smith
Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Am J Prev Med 44:373-81. 2013..The 13-valent pneumococcal conjugate vaccine (PCV13) is approved by the U.S. Food and Drug Administration for adults, but its role in older adults is unclear... - Should vascular surgery patients be screened preoperatively for methicillin-resistant Staphylococcus aureus?Bruce Y Lee
Section of Decision Sciences and Clinical Systems Modeling, Department of Biomedical Informatics, School of Medicine, and Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Infect Control Hosp Epidemiol 30:1158-65. 2009..Testing all vascular surgery patients preoperatively for MRSA and attempting to decolonize those who have positive results may be a strategy to prevent MRSA infection. The economic value of such a strategy has not yet been determined... - The cost-effectiveness of community-based screening for oral cancer in high-risk males in the United States: a Markov decision analysis approachRaj C Dedhia
Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15203, USA
Laryngoscope 121:952-60. 2011.... - A cost-effectiveness analysis of coagulation testing prior to tonsillectomy and adenoidectomy in childrenJames D Cooper
Division of Hematology Oncology BMT, Department of Pediatrics, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA
Pediatr Blood Cancer 55:1153-9. 2010..Studies of pre-operative screening have had conflicting results. A decision analysis model was constructed to address the costs and health outcome states of pre-operative screening strategies in children... - Alternative strategies for adult pneumococcal polysaccharide vaccination: a cost-effectiveness analysisKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States
Vaccine 26:1420-31. 2008..PPV at ages 50/65 may be clinically and, depending on cost-effectiveness criterion used, economically favored over present vaccination recommendations... - Estimating the cost-effectiveness of a national program to eliminate disparities in influenza vaccination rates among elderly minority groupsConstantinos I Michaelidis
University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, United States
Vaccine 29:3525-30. 2011..In an analysis using conservative assumptions, we found that a hypothetical program to ameliorate disparities in influenza vaccination rates has a moderate to high likelihood of being cost-effective... - Time from sexually transmitted infection acquisition to pelvic inflammatory disease development: influence on the cost-effectiveness of different screening intervalsKenneth J Smith
School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Value Health 10:358-66. 2007..Nevertheless, the time from STI acquisition to PID development, possibly an important factor to consider in screening interval choice, is unknown and its influence on the effectiveness and cost-effectiveness of screening is unclear... - Cost-effectiveness of implantable cardioverter-defibrillators in children with dilated cardiomyopathyBrian Feingold
Division of Pediatric Cardiology, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA
J Card Fail 16:734-41. 2010..Because of differences in heart failure etiology, sudden death rates, and ICD complication rates, these findings may not be applicable to children... - Optimal approach to improving trauma triage decisions: a cost-effectiveness analysisDeepika Mohan
The CRISMA Laboratory, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Am J Manag Care 18:e91-e100. 2012..To identify the optimal target of a future intervention to improve physician decision making in trauma triage... - Cost impact of molecular testing for indeterminate thyroid nodule fine-needle aspiration biopsiesLinwah Yip
Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Clin Endocrinol Metab 97:1905-12. 2012..We hypothesized that FNA molecular testing of two indeterminate categories (follicular lesion of undetermined significance and follicular/Hürthle cell neoplasm) can be cost saving... - Cost-effectiveness analysis of efforts to reduce risk of type 2 diabetes and cardiovascular disease in southwestern Pennsylvania, 2005-2007Kenneth J Smith
University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Prev Chronic Dis 7:A109. 2010..We assessed the cost-effectiveness of a community-based, modified Diabetes Prevention Program (DPP) designed to reduce risk factors for type 2 diabetes and cardiovascular disease... - Cost-utility analysis of von Willebrand disease screening in adolescents with menorrhagiaRobert Francis Sidonio
Division of Pediatric Hematology Oncology, Children s Hospital of Pittsburgh University of Pittsburgh Medical Center, Pittsburgh, PA 15201, USA
J Pediatr 157:456-60, 460.e1. 2010..To construct a decision analysis model to evaluate the cost utility of von Willebrand disease (VWD) testing in adolescents with menorrhagia... - Should female relatives of factor V Leiden carriers be screened prior to oral contraceptive use? A cost-effectiveness analysisKenneth J Smith
Medicine Hematology Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 4306, USA
Thromb Haemost 100:447-52. 2008..In conclusion, screening, counselling and prophylactic AC during high-risk periods in female relatives of FVL carriers is an economically favourable strategy... - Hospitalization for pelvic inflammatory disease: a cost-effectiveness analysisKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 34:108-12. 2007..Nulliparous women are frequently hospitalized for treatment of pelvic inflammatory disease (PID)... - Cost comparisons between home- and clinic-based testing for sexually transmitted diseases in high-risk young womenKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Infect Dis Obstet Gynecol 2007:62467. 2007..A home testing program could be cost saving, depending on whether changes in clinic testing frequency occur when home testing is available... - Cost-effectiveness of a program to eliminate disparities in pneumococcal vaccination rates in elderly minority populations: an exploratory analysisConstantinos I Michaelidis
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Electronic address
Value Health 16:311-7. 2013..Here, we estimate the cost-effectiveness of a hypothetical national vaccination intervention program designed to eliminate racial disparities in pneumococcal vaccination in the elderly... - Teaching medical decision modeling: a qualitative description of student errors and curriculum responsesKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Med Decis Making 26:583-8. 2006..Originally, the only assignment was an abstract and 10-minute presentation describing their solution, but now periodic homework monitors progress... - Consolidation paclitaxel is more cost-effective than bevacizumab following upfront treatment of advanced epithelial ovarian cancerJamie L Lesnock
Dept of ObGyn, Division of Gynecologic Oncology, Magee Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Gynecol Oncol 122:473-8. 2011..We sought to evaluate the cost-effectiveness (C/E) of these consolidation strategies... - Reliability of laparoscopic compared with hysteroscopic sterilization at 1 year: a decision analysisAileen M Gariepy
Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of General Internal Medicine, Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Obstet Gynecol 118:273-9. 2011..To estimate the probability of successful sterilization after an hysteroscopic or laparoscopic sterilization procedure... - Cost-effectiveness of guidelines for insertion of inferior vena cava filters in high-risk trauma patientsEmily L Spangler
University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Vasc Surg 52:1537-45.e1-2. 2010..This analysis compares cost-effectiveness of prophylactic vs therapeutic retrievable IVCF placement in high-risk trauma patients... - Managing mesh exposure following vaginal prolapse repair: a decision analysis comparing conservative versus surgical treatmentLaura C Skoczylas
Division of Urogynecology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Int Urogynecol J 24:119-25. 2013..A decision analysis model was developed comparing conservative and surgical treatments in the management of synthetic mesh exposure following vaginal prolapse repair. We hypothesized that surgical excision would be favored... - Sequential medication strategies for postherpetic neuralgia: a cost-effectiveness analysisKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Pain 8:396-404. 2007..This decision analysis-based synthesis of effectiveness and cost data found that recommended treatment algorithms are also economically reasonable... - Retropubic and transobturator midurethral slings: a decision analysis to compare outcomes including efficacy and complicationsJonathan P Shepherd
Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Pittsburgh Medical Center, Magee Women s Hospital, Pittsburgh, PA, USA
Int Urogynecol J 21:787-93. 2010..The objective of this paper is to compare retropubic (RP) and transobturator (TO) midurethral slings using decision analysis techniques... - Prophylactic antibiotics to prevent urinary tract infection during clean intermittent self-catheterization (CISC) for management of voiding dysfunction after prolapse and incontinence surgery: a decision analysisGary Sutkin
Division of Urogynecology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Hospital, University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh, PA 15213, USA
Int Urogynecol J Pelvic Floor Dysfunct 20:933-8. 2009..The objective of this study is to estimate efficacy of prophylactic antibiotics in UTI prevention during CISC for postoperative voiding dysfunction after prolapse/incontinence surgery... - A cost-utility analysis of treatment for acute childhood idiopathic thrombocytopenic purpura (ITP)Sarah H O'Brien
Pediatric Hematology Oncology, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Pediatr Blood Cancer 48:173-80. 2007..The primary objective in the treatment of acute pediatric idiopathic thrombocytopenic purpura (ITP) is to rapidly increase the platelet count... - Cost-effectiveness of pneumococcal and influenza vaccination standing order programsChyongchiou Jeng Lin
Department of Family Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Am J Manag Care 19:e30-7. 2013..Here we examine the cost-effectiveness of SOPs to improve both pneumococcal and influenza vaccination rates in outpatient settings for individuals 65 years and older... - Oral anticoagulation strategies after a first idiopathic venous thromboembolic eventDrahomir Aujesky
Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, Pennsylvania, USA
Am J Med 118:625-35. 2005..We used decision analysis to evaluate clinical and economic outcomes of different anticoagulation strategies with warfarin... - Direct paramedic transport of acute myocardial infarction patients to percutaneous coronary intervention centers: a decision analysisHenry E Wang
Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Ann Emerg Med 53:233-240. 2009.... - Contraceptive effectiveness of immediate compared with delayed insertion of intrauterine devices after abortion: a decision analysisMatthew F Reeves
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine and the Magee Womens Research Institute, Pittsburgh, Pennsylvania 15213 3180, USA
Obstet Gynecol 109:1286-94. 2007..To model rates of pregnancy and repeat abortion among women choosing intrauterine contraception after an abortion when the intrauterine device (IUD) is inserted immediately after the procedure or at a follow-up visit... - Cost-identification analysis of total laryngectomy: an itemized approach to hospital costsRaj C Dedhia
Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Otolaryngol Head Neck Surg 144:220-4. 2011.... - Optimizing the timing of chemotherapy for mobilizing autologous blood hematopoietic progenitor cellsMichelle L Hicks
Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA
Transfusion 47:629-35. 2007..Postchemotherapy mobilization results were reviewed in patients undergoing apheresis before planned autologous hematopoietic progenitor cell (HPC) transplantation to improve the timing of collection procedures... - Prediction of pelvic inflammatory disease among young, single, sexually active womenRoberta B Ness
Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA
Sex Transm Dis 33:137-42. 2006..To assess prediction strategies for pelvic inflammatory disease (PID)... - Cost-effectiveness of a vaccine to prevent herpes zoster and postherpetic neuralgia in older adultsMichael B Rothberg
Division of General Medicine and Geriatrics, Department of Medicine, Baystate Medical Center, Springfield, MA 01199, USA
Clin Infect Dis 44:1280-8. 2007..A vaccine to prevent herpes zoster was recently approved by the United States Food and Drug Administration. We sought to determine the cost-effectiveness of this vaccine for different age groups... - Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?Christina Marik
Centre for Brain Research, Medical University of Vienna, Austria
Brain 130:2800-15. 2007..The findings indicate that mechanisms associated with innate immunity may play a role in the formation of hypoxia-like demyelinating lesions in MS... - Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharidePaul A Felts
Department of Neuroimmunology and Neuroinflammation Research Group, Guy s, King s and St Thomas School of Medicine, King s College London, London, UK
Brain 128:1649-66. 2005..2000), and we therefore suggest that LPS-induced demyelination may serve as the first experimental model available for the study of this type of multiple sclerosis lesion...