Research Topics
| J M SmithSummaryAffiliation: University of Washington Country: USA Publications
Research Grants
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Detail Information
Publications
Subclinical viremia increases risk for chronic allograft injury in pediatric renal transplantationJodi M Smith
Department of Pediatrics, University of Washington, Seattle, Washington, USA
J Am Soc Nephrol 21:1579-86. 2010..Taken together, these results demonstrate an association between subclinical CMV and EBV infections, which occur despite standard antiviral prophylaxis, and chronic allograft injury in pediatric renal transplant recipients...
Current state of pediatric renal transplantationJodi M Smith
Department of Pediatrics, Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA 98105, USA
Front Biosci 13:197-203. 2008..The current objective of pediatric renal transplantation is to develop management strategies which minimize or eliminate immunosuppression morbidities in order to maximize the growth and development of this unique population...
BK virus nephropathy in pediatric renal transplant recipients: an analysis of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) registryJodi M Smith
Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, M1 5, Seattle, WA 98105, USA
Clin J Am Soc Nephrol 2:1037-42. 2007..The objective of this study was to evaluate cases of BK virus nephropathy in the North American Pediatric Renal Trials and Collaborative Studies database...
Adolescents are more likely to develop posttransplant lymphoproliferative disorder after primary Epstein-Barr virus infection than younger renal transplant recipientsJodi M Smith
Department of Pediatrics, Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA 98105, USA
Transplantation 83:1423-8. 2007..Pediatric patients are often EBV seronegative pretransplant placing them at high risk. In the immune-competent population, primary herpesvirus infection is associated with higher morbidity with increasing age...
Emerging viral infections in transplantationJodi M Smith
Department of Pediatrics, University of Washington, Seattle, WA, USA
Pediatr Transplant 10:838-43. 2006..This review focuses on the emergence of the herpesviruses; HHV-6 and HHV-7. In addition, the issue of virus transmission through organ transplant is addressed with a discussion of West Nile virus and the rabies virus...
Decreased risk of renal allograft thrombosis associated with interleukin-2 receptor antagonists: a report of the NAPRTCSJ M Smith
Department of Pediatrics, Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, Seattle, Washington, USA
Am J Transplant 6:585-8. 2006..This provocative finding requires further investigation to determine whether thrombotic failure can be decreased by this therapeutic strategy...
Risk of lymphoma after renal transplantation varies with time: an analysis of the United States Renal Data SystemJodi M Smith
Department of Pediatrics, Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA 98105, USA
Transplantation 81:175-80. 2006..We analyzed the United States Renal Data System to describe the occurrence of lymphoma following renal transplantation...
Renal transplantation in adolescentsJodi M Smith
Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, M1 5, Seattle, WA 98105, USA
Adolesc Med Clin 16:201-14. 2005..Strategies to address the unique concerns of this high-risk population, including the use of a multidisciplinary team, are essential to improving outcomes...
Current immunosuppressive agents in pediatric renal transplantation: efficacy, side-effects and utilizationJodi M Smith
Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way, Seattle, WA 98105, USA
Pediatr Transplant 8:445-53. 2004..The goal remains to find the best combination that will optimize graft survival, while minimizing the adverse effects...
Current immunosuppressive agents: efficacy, side effects, and utilizationJodi M Smith
Division of Nephrology, Children s Hospital and Regional Medical Center, 4800 Sand Point Way, NE 5G 1, Seattle, WA 98105 0371, USA
Pediatr Clin North Am 50:1283-300. 2003..The ultimate goal of transplant immunosuppressive therapy is the induction of tolerance. As we learn more about immune function from basic and clinical research, tolerance to allografts seems a more reachable goal...
Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroidsR A McDonald
University of Washington and Children s Hospital and Regional Medical Center, Seattle, WA, USA
Am J Transplant 8:984-9. 2008..Future studies must include routine viral monitoring to permit early identification of viral activity and a protocol driven reduction of immunosuppression aimed at avoiding complications...
Contributions of the Transplant Registry: The 2006 Annual Report of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)Jodi M Smith
Department of Pediatrics, University of Washington, Seattle, WA, USA
Pediatr Transplant 11:366-73. 2007..The registry has served to document and influence practice patterns, clinical outcomes, and changing trends in renal transplantation...
Childhood asthma hospitalization risk after cesarean delivery in former term and premature infantsJason S Debley
Division of Pulmonary Medicine, University of Washington, Seattle, Washington, USA
Ann Allergy Asthma Immunol 94:228-33. 2005..Results of previous studies regarding an association between birth route and asthma are conflicting, and these studies have not evaluated some potential confounding effects, including prematurity and maternal asthma...
Impaired graft survival in pediatric renal transplant recipients with donor-specific antibodies detected by solid-phase assaysPriya S Verghese
Department of Pediatric Nephrology, University of Washington and Seattle Children s Hospital, Seattle, Washington 98105, USA
Pediatr Transplant 14:730-4. 2010..5). SAB-detected DSA was associated with impaired renal allograft survival in pediatric renal transplant recipients. Impaired graft survival in pediatric renal transplant recipients with DSA detected by solid-phase assays...
Pretransplant peritoneal dialysis and graft thrombosis following pediatric kidney transplantation: a NAPRTCS reportRuth A McDonald
Division of Nephrology, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA, USA
Pediatr Transplant 7:204-8. 2003..We conclude that pretransplant PD is associated with an increased risk of graft thrombosis. Special precautions should be undertaken in pediatric renal transplant patients who have received PD, especially infants and young children...
Nephrotic syndrome in the newbornLaura S Finn
Department of Laboratories, Children's Hospital and Regional Medical Center, Seattle, WA 98105, USA
Am J Kidney Dis 42:1318-23. 2003
Polyomavirus nephropathy in pediatric kidney transplant recipientsJodi M Smith
Department of Pediatrics, Division of Nephrology, University of Washington, Seattle, WA, USA
Am J Transplant 4:2109-17. 2004..Further studies to confirm this finding and to define the clinical utility of routine pre-transplant BKV serologic testing are warranted...
Renal transplant outcomes in adolescents: a report of the North American Pediatric Renal Transplant Cooperative StudyJodi M Smith
Division of Nephrology, Children's Hospital and Regional Medical Center, University of Washington, Seattle, Washington 98105-0371, USA
Pediatr Transplant 6:493-9. 2002..Lack of compliance with immunosuppression regimens may be an important contributory factor. Strategies to address the unique concerns of this high-risk population will be essential to improve outcomes...
Sonic tooth brushing reduces gingival overgrowth in renal transplant recipientsJodi M Smith
Pediatric Nephrology, Children's Hospital and Regional Medical Center, Seattle, WA, USA
Pediatr Nephrol 21:1753-9. 2006..1, 95%CI=2.3-16.1, P=0.03). The use of a powered toothbrush, together with oral hygiene instruction, may be an important component of health maintenance for pediatric transplant patients on CSA...
Platelet-activating factor and Escherichia coliO157:H7 infectionsJodi M Smith
Division of Nephrology, Children's Hospital and Regional Medical Center, Department of Pediatrics, University of Washington, Seattle, Washington, USA
Pediatr Nephrol 17:1047-52. 2002..Thus, elevated plasma PAF levels occur in E. coliO157:H7-infected children, even without HUS, but diminish when HUS develops. The PAF-AH ( G994T) allele does not contribute to the risk of developing HUS...
Research Grants
- Renal transplant and subclinical herpesvirus infectionJodi Smith; Fiscal Year: 2007..abstract_text> ..
