Eric P Smith

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. doi request reprint Recent experimental and clinical findings in the skeleton associated with loss of estrogen hormone or estrogen receptor activity
    Eric P Smith
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    J Steroid Biochem Mol Biol 118:264-72. 2010
  2. pmc Impact on bone of an estrogen receptor-alpha gene loss of function mutation
    Eric P Smith
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Cincinnati College of Medicine, Vontz Center for Molecular Studies, 3125 Eden Avenue, Cincinnati, Ohio 45267 0547, USA
    J Clin Endocrinol Metab 93:3088-96. 2008
  3. ncbi request reprint Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation
    Jeffrey A Knauf
    Division of Endocrinology and Department of Pathology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0547, USA
    Cancer Res 65:4238-45. 2005
  4. pmc Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective
    Eric M Jacobson
    Division of Endocrinology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45220, USA
    J Biol Chem 284:34231-43. 2009
  5. pmc Red cell life span heterogeneity in hematologically normal people is sufficient to alter HbA1c
    Robert M Cohen
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of Cincinnati College of Medicine, Vontz Center for Molecular Studies, 3125 Eden Avenue, Cincinnati, OH 45267 0547, USA
    Blood 112:4284-91. 2008
  6. doi request reprint Frequency of HbA1c discordance in estimating blood glucose control
    Robert M Cohen
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0547, USA
    Curr Opin Clin Nutr Metab Care 11:512-7. 2008
  7. doi request reprint A method for the continuous calculation of the age of labeled red blood cells
    Christopher J Lindsell
    Department of Emergency Medicine, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA
    Am J Hematol 83:454-7. 2008
  8. ncbi request reprint Relationship of prospective GHb to glycated serum proteins in incident diabetic retinopathy: implications of the glycation gap for mechanism of risk prediction
    Robert M Cohen
    Division of Endocrinology, Metabolism and Diabetes, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
    Diabetes Care 31:151-3. 2008
  9. pmc Evidence for interindividual heterogeneity in the glucose gradient across the human red blood cell membrane and its relationship to hemoglobin glycation
    Paramjit K Khera
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
    Diabetes 57:2445-52. 2008
  10. ncbi request reprint Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo
    Bin Ouyang
    Division of Endocrinology and Metabolism, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0547, USA
    Clin Cancer Res 12:1785-93. 2006

Collaborators

Detail Information

Publications12

  1. doi request reprint Recent experimental and clinical findings in the skeleton associated with loss of estrogen hormone or estrogen receptor activity
    Eric P Smith
    Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    J Steroid Biochem Mol Biol 118:264-72. 2010
    ..Importantly, androgen, particularly by preserving trabecular number and augmenting both periosteal and epiphyseal growth, also has significant actions on bone...
  2. pmc Impact on bone of an estrogen receptor-alpha gene loss of function mutation
    Eric P Smith
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Cincinnati College of Medicine, Vontz Center for Molecular Studies, 3125 Eden Avenue, Cincinnati, Ohio 45267 0547, USA
    J Clin Endocrinol Metab 93:3088-96. 2008
    ..The kindred described is the only known instance of a germ line loss of function mutation of estrogen receptor (ER)-alpha...
  3. ncbi request reprint Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation
    Jeffrey A Knauf
    Division of Endocrinology and Department of Pathology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0547, USA
    Cancer Res 65:4238-45. 2005
    ..This closely recapitulates the phenotype of BRAF-positive PTCs in humans and supports a key role for this oncogene in its pathogenesis...
  4. pmc Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective
    Eric M Jacobson
    Division of Endocrinology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45220, USA
    J Biol Chem 284:34231-43. 2009
    ..Our study suggests that interactions between Tg and discrete HLA-DR pocket signatures contribute to the initiation of AITD...
  5. pmc Red cell life span heterogeneity in hematologically normal people is sufficient to alter HbA1c
    Robert M Cohen
    Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of Cincinnati College of Medicine, Vontz Center for Molecular Studies, 3125 Eden Avenue, Cincinnati, OH 45267 0547, USA
    Blood 112:4284-91. 2008
    ..HbA1c synthesis was linear and correlated with mean whole blood HbA1c (R(2) = 0.91). The observed variation in RBC survival was large enough to cause clinically important differences in HbA1c for a given mean blood glucose...
  6. doi request reprint Frequency of HbA1c discordance in estimating blood glucose control
    Robert M Cohen
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0547, USA
    Curr Opin Clin Nutr Metab Care 11:512-7. 2008
    ..HbA1c is a trusted standard for monitoring glycemic control and predicting complications. However, there are emerging issues complicating the interpretation of HbA1c that the clinician caring for patients with diabetes needs to consider...
  7. doi request reprint A method for the continuous calculation of the age of labeled red blood cells
    Christopher J Lindsell
    Department of Emergency Medicine, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA
    Am J Hematol 83:454-7. 2008
    ..It is expected that this analytical approach will be useful in the study of age-dependent RBC changes...
  8. ncbi request reprint Relationship of prospective GHb to glycated serum proteins in incident diabetic retinopathy: implications of the glycation gap for mechanism of risk prediction
    Robert M Cohen
    Division of Endocrinology, Metabolism and Diabetes, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
    Diabetes Care 31:151-3. 2008
  9. pmc Evidence for interindividual heterogeneity in the glucose gradient across the human red blood cell membrane and its relationship to hemoglobin glycation
    Paramjit K Khera
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
    Diabetes 57:2445-52. 2008
    ..To determine whether interindividual heterogeneity in the erythrocyte (red blood cell [RBC]) transmembrane glucose gradient might explain discordances between A1C and glycemic control based on measured fructosamine...
  10. ncbi request reprint Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo
    Bin Ouyang
    Division of Endocrinology and Metabolism, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0547, USA
    Clin Cancer Res 12:1785-93. 2006
    ..We postulated that compounds that inhibit a distal effector in the mitogen-activated protein kinase (MAPK) pathway would inhibit growth and tumorigenicity of human thyroid cancer cell lines with mutations of RET or BRAF...
  11. ncbi request reprint Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy
    MingYu Zhang
    Division of Endocrinology, University of Cincinnati College of Medicine and the Children s Hospital Medical Center, Cincinnati, Ohio 45267 0547, USA
    J Biol Chem 277:21285-90. 2002
    ..Thus, IGFBP-4.7A results in greater growth inhibition than equivalent levels of native IGFBP-4 in vivo, demonstrating a role for IGFBP-4 proteolysis in the regulation of IGF-I action...
  12. ncbi request reprint Smooth muscle overexpression of IGF-I induces a novel adaptive response to small bowel resection
    Andrew W Knott
    Division of Pediatric Surgery, Department of Surgery, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Mediicne, Cincinnati, Ohio 45229 3039, USA
    Am J Physiol Gastrointest Liver Physiol 287:G562-70. 2004
    ..IGF-I signaling within the muscle wall may play an important role in the pathogenesis of resection-induced adaptation...