Elaine Smith

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Predictors of Chlamydia trachomatis infection among women attending rural Midwest family planning clinics
    T M Hilger
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, USA
    Infect Dis Obstet Gynecol 9:3-8. 2001
  2. pmc Human papillomavirus serologic follow-up response and relationship to survival in head and neck cancer: a case-comparison study
    Linda M Rubenstein
    Department of Epidemiology College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Infect Agent Cancer 6:9. 2011
  3. ncbi request reprint P16INK4a expression, human papillomavirus, and survival in head and neck cancer
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Oral Oncol 44:133-42. 2008
  4. doi request reprint Association between p53 and human papillomavirus in head and neck cancer survival
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Cancer Epidemiol Biomarkers Prev 17:421-7. 2008
  5. ncbi request reprint Age, sexual behavior and human papillomavirus infection in oral cavity and oropharyngeal cancers
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Int J Cancer 108:766-72. 2004
  6. doi request reprint Does pretreatment seropositivity to human papillomavirus have prognostic significance for head and neck cancers?
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Cancer Epidemiol Biomarkers Prev 17:2087-96. 2008
  7. ncbi request reprint Persistent HPV infection in postmenopausal age women
    E M Smith
    Department of Epidemiology, 2800 SB, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Int J Gynaecol Obstet 87:131-7. 2004
  8. doi request reprint Risk factors and survival by HPV-16 E6 and E7 antibody status in human papillomavirus positive head and neck cancer
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Int J Cancer 127:111-7. 2010
  9. pmc HPV prevalence and concordance in the cervix and oral cavity of pregnant women
    E M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Infect Dis Obstet Gynecol 12:45-56. 2004
  10. ncbi request reprint Prevalence of human papillomavirus in the oral cavity/oropharynx in a large population of children and adolescents
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Pediatr Infect Dis J 26:836-40. 2007

Research Grants

  1. International Collaborative HNC Research
    Elaine Smith; Fiscal Year: 2007
  2. Transcripitonal and Genetic Profiles in HNSCCs
    Elaine Smith; Fiscal Year: 2007
  3. GENETIC EPIDEMIOLOGY AND MECHANISMS IN ORAL CANCER
    Elaine Smith; Fiscal Year: 2003

Collaborators

Detail Information

Publications34

  1. pmc Predictors of Chlamydia trachomatis infection among women attending rural Midwest family planning clinics
    T M Hilger
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, USA
    Infect Dis Obstet Gynecol 9:3-8. 2001
    ..In addition, screening guidelines would be more difficult to implement in a rural setting...
  2. pmc Human papillomavirus serologic follow-up response and relationship to survival in head and neck cancer: a case-comparison study
    Linda M Rubenstein
    Department of Epidemiology College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Infect Agent Cancer 6:9. 2011
    ..abstract:..
  3. ncbi request reprint P16INK4a expression, human papillomavirus, and survival in head and neck cancer
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Oral Oncol 44:133-42. 2008
    ....
  4. doi request reprint Association between p53 and human papillomavirus in head and neck cancer survival
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Cancer Epidemiol Biomarkers Prev 17:421-7. 2008
    ..In addition, HPV and p53 have been associated with prognosis of these tumors but the findings have been inconsistent. We examined p53 expression and HPV-HR individually and jointly for differences in predicting HNC survival...
  5. ncbi request reprint Age, sexual behavior and human papillomavirus infection in oral cavity and oropharyngeal cancers
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Int J Cancer 108:766-72. 2004
    ..An exfoliated oral cytology test for HPV was a significant predictor of HR types in the cancers, suggesting that an oral rinse may provide an early biomarker of infected tumors...
  6. doi request reprint Does pretreatment seropositivity to human papillomavirus have prognostic significance for head and neck cancers?
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Cancer Epidemiol Biomarkers Prev 17:2087-96. 2008
    ..Human papillomavirus (HPV) is a risk factor for head and neck cancers (HNC), yet HPV-associated tumors have better prognosis than HPV-negative tumors...
  7. ncbi request reprint Persistent HPV infection in postmenopausal age women
    E M Smith
    Department of Epidemiology, 2800 SB, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Int J Gynaecol Obstet 87:131-7. 2004
    ..Because this association in older, postmenopausal age women has received little attention, we evaluated persistence of HPV among women in this age group...
  8. doi request reprint Risk factors and survival by HPV-16 E6 and E7 antibody status in human papillomavirus positive head and neck cancer
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Int J Cancer 127:111-7. 2010
    ..Differences in antibody status are associated with distinct risk factors and clinical outcomes. This information can be available as a simple blood test at initial presentation, before the removal of tissue through biopsy or surgery...
  9. pmc HPV prevalence and concordance in the cervix and oral cavity of pregnant women
    E M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Infect Dis Obstet Gynecol 12:45-56. 2004
    ..This investigation examined human papillomavirus (HPV) in pregnant women in order to characterize viral prevalence, types and concordance between infection in the cervix and in the oral cavity...
  10. ncbi request reprint Prevalence of human papillomavirus in the oral cavity/oropharynx in a large population of children and adolescents
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Pediatr Infect Dis J 26:836-40. 2007
    ..We evaluated the prevalence of HPV DNA in the oral cavity/oropharynx in a cross section of children aged 2 weeks to 20 years...
  11. pmc Human papillomavirus, p16 and p53 expression associated with survival of head and neck cancer
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Infect Agent Cancer 5:4. 2010
    ..P16 and p53 expression were detected from formalin-fixed, paraffin-embedded tissues by immunohistochemical staining. HPV DNA was detected by PCR and DNA sequencing in 237 histologically confirmed HNC patients...
  12. ncbi request reprint Human papillomavirus seropositivity and risks of head and neck cancer
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Int J Cancer 120:825-32. 2007
    ..Because of the survival advantage of HPV-related HNC, HPV-16 E6/E7 detection may be useful in therapy targeted for HPV-related tumors...
  13. ncbi request reprint Human papillomavirus in oral exfoliated cells and risk of head and neck cancer
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
    J Natl Cancer Inst 96:449-55. 2004
    ....
  14. ncbi request reprint Human papillomavirus prevalence and types in newborns and parents: concordance and modes of transmission
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
    Sex Transm Dis 31:57-62. 2004
    ..The purpose of this investigation was to determine the risk of vertical and early contact transmission of human papillomavirus (HPV) in newborn infants based on concordance and sequence match to HPV types in parents...
  15. ncbi request reprint Prevalence and persistence of human papillomavirus in postmenopausal age women
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, 200 Hawkins Drive, C21P GH, Iowa City, IA 52242, USA
    Cancer Detect Prev 27:472-80. 2003
    ..1-3.1). These findings suggest that a significant percentage of older women are infected with HPV. This may put them at increased risk of genital cancers with longer use of HRTs. Additional studies are needed...
  16. doi request reprint Tobacco and alcohol use increases the risk of both HPV-associated and HPV-independent head and neck cancers
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Cancer Causes Control 21:1369-78. 2010
    ....
  17. pmc Case-control study of vulvar vestibulitis risk associated with genital infections
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Infect Dis Obstet Gynecol 10:193-202. 2002
    ..To evaluate the risk of vulvar vestibulitis syndrome (VVS) associated with genital infections in a case-control study...
  18. ncbi request reprint Is use of hormone replacement therapy associated with increased detection of human papillomavirus and potential risk of HPV-related genital cancers?
    E M Smith
    Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
    Eur J Cancer Prev 11:295-305. 2002
    ....
  19. pmc Human papillomavirus type 16 (HPV-16) genomes integrated in head and neck cancers and in HPV-16-immortalized human keratinocyte clones express chimeric virus-cell mRNAs similar to those found in cervical cancers
    Michael J Lace
    Department of Pathology, University of Iowa Roy J and Lucille A Carver College ofMedicine, Veterans Affairs Medical Center, Iowa City, Iowa 52242, USA
    J Virol 85:1645-54. 2011
    ..Furthermore, our results demonstrate that this selection also takes place and can be studied in primary human keratinocytes in culture...
  20. pmc Evidence for vertical transmission of HPV from mothers to infants
    Elaine M Smith
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Infect Dis Obstet Gynecol 2010:326369. 2010
    ..None of the mother/baby HPV DNA+ concordance pairs detected viral types found in HPV vaccines suggesting that vaccination prior to pregnancy is unlikely to be efficacious in preventing vertical transmission...
  21. ncbi request reprint Human papillomavirus infection as a prognostic factor in carcinomas of the oral cavity and oropharynx
    Justine M Ritchie
    Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Int J Cancer 104:336-44. 2003
    ..HPV status was identified as an independent prognostic factor in oral and oropharyngeal cancers. This result appeared to be gender-specific, suggesting the need for further study of the interaction between HPV and gender on survival...
  22. ncbi request reprint Gonorrhea and chlamydia infection among women visiting family planning clinics: racial variation in prevalence and predictors
    Lisa A Einwalter
    University of Iowa, College of Public Health, Iowa City, IA, USA
    Perspect Sex Reprod Health 37:135-40. 2005
    ..Because of the potential impact of these infections on women's reproductive health, it is important to determine whether different factors are predictive of infection in women of different races...
  23. ncbi request reprint Alcohol dehydrogenase 3 and risk of squamous cell carcinomas of the head and neck
    Donghong Wang
    Department of Epidemilogy, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Cancer Epidemiol Biomarkers Prev 14:626-32. 2005
    ..However, participants with ADH3(1-2) genotype were associated with poorer survival compared with those who had the other two ADH3 genotypes and a higher rate of recurrence than participants with ADH3(1-1) genotype...
  24. ncbi request reprint Organochlorines and risk of prostate cancer
    Justine M Ritchie
    Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    J Occup Environ Med 45:692-702. 2003
    ..This study suggests that long-term, low-dose exposure to specific OCPs and PCBs in the general population may contribute to an increased risk of prostate cancer and supports further investigation in this area...
  25. ncbi request reprint Comparison of proposed frameworks for grouping polychlorinated biphenyl congener data applied to a case-control pilot study of prostate cancer
    Justine M Ritchie
    Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Environ Res 98:104-13. 2005
    ..These results suggest that a higher burden of PCBs that are CAR agonists may be positively associated with an increased risk of prostate cancer and they encourage further research in this area...
  26. pmc Cigarette, cigar, and pipe smoking and the risk of head and neck cancers: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium
    Annah Wyss
    Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, NC 27599, USA
    Am J Epidemiol 178:679-90. 2013
    ..49, 95% CI: 2.58, 4.73) or exclusive pipe smoking (odds ratio = 3.71, 95% CI: 2.59, 5.33). These results suggest that cigar and pipe smoking are independently associated with increased risk of head and neck cancers. ..
  27. ncbi request reprint Physician specialty is significantly associated with hormone replacement therapy use
    Barcey T Levy
    Department of Family Medicine, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Obstet Gynecol 101:114-22. 2003
    ..To compare the characteristics of postmenopausal women seen by gynecologists versus family physicians and to determine factors associated with current hormone replacement therapy (HRT) use...
  28. ncbi request reprint Head and neck cancer associated with herpes simplex virus 1 and 2 and other risk factors
    Tina M Parker
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Oral Oncol 42:288-96. 2006
    ..7) or HSV-2 (not estimable). These findings suggest that seropositivity to HSV-1 and HSV-2, although not independent risk factors for HNC, may modify the risk of HNC associated with exposure to tobacco, alcohol, or HPV-HR...
  29. ncbi request reprint Voice disorders in teachers and the general population: effects on work performance, attendance, and future career choices
    Nelson Roy
    Department of Communication Sciences and Disorders, The University of Utah, Salt Lake City, 84112 0252, USA
    J Speech Lang Hear Res 47:542-51. 2004
    ..05). These findings strongly suggest that occupationally related voice dysfunction in teachers can have significant adverse effects on job performance, attendance, and future career choices...
  30. ncbi request reprint Prevalence of voice disorders in teachers and the general population
    Nelson Roy
    Department of Communication Sciences and Disorders, The University of Utah, Salt Lake City, UT, USA
    J Speech Lang Hear Res 47:281-93. 2004
    ..These results support the notion that teaching is a high-risk occupation for voice disorders. Important information is also provided regarding additional factors that might contribute to the development of voice disorders...
  31. pmc Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers
    Dohun Pyeon
    McArdle Laboratory for Cancer Research, University of Wisconsin Madison, Madison, WI 53706, USA
    Cancer Res 67:4605-19. 2007
    ....
  32. ncbi request reprint Voice disorders in the general population: prevalence, risk factors, and occupational impact
    Nelson Roy
    Department of Communication Sciences and Disorders, The University of Utah, Salt Lake City, Utah 84112 0252, USA
    Laryngoscope 115:1988-95. 2005
    ....
  33. ncbi request reprint Occupational risk factors associated with voice disorders among teachers
    Susan L Thibeault
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, The University of Utah, Salt Lake City, UT 84132, USA
    Ann Epidemiol 14:786-92. 2004
    ..This study was designed to determine the occupational risk factors associated with voice disorders among schoolteachers, a high-risk population for developing voice problems...
  34. pmc A functional role for Anopheles gambiae Arrestin1 in olfactory signal transduction
    William B Walker
    Department of Biological Sciences, Centers for Molecular Neuroscience and Global Health and Programs in Development, Genetics Vanderbilt University, Nashville, TN 37232, USA
    J Insect Physiol 54:680-90. 2008
    ..gambiae...

Research Grants13

  1. International Collaborative HNC Research
    Elaine Smith; Fiscal Year: 2007
    ..This aim is to determine whether there is an easily administered, sensitive biomarker that can predict HPV-HR status in HNC tumors prior to therapy.. ..
  2. Transcripitonal and Genetic Profiles in HNSCCs
    Elaine Smith; Fiscal Year: 2007
    ..abstract_text> ..
  3. GENETIC EPIDEMIOLOGY AND MECHANISMS IN ORAL CANCER
    Elaine Smith; Fiscal Year: 2003
    ..abstract_text> ..