Earl Smith

Summary

Affiliation: University of Houston
Country: USA

Publications

  1. pmc Wave aberrations in rhesus monkeys with vision-induced ametropias
    Ramkumar Ramamirtham
    College of Optometry, University of Houston, 505 J Davis Armistead Building, Houston, TX 77204 2020, USA
    Vision Res 47:2751-66. 2007
  2. pmc Optical treatment strategies to slow myopia progression: Effects of the visual extent of the optical treatment zone
    Earl L Smith
    College of Optometry, University of Houston, 505 J Davis Armistead Building, Houston, TX 77204 2020, USA Vision Cooperative Research Centre, Sydney, Australia Electronic address
    Exp Eye Res 114:77-88. 2013
  3. pmc Negative lens-induced myopia in infant monkeys: effects of high ambient lighting
    Earl L Smith
    College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    Invest Ophthalmol Vis Sci 54:2959-69. 2013
  4. doi request reprint Does peripheral retinal input explain the promising myopia control effects of corneal reshaping therapy (CRT or ortho-K) & multifocal soft contact lenses?
    Earl L Smith
    University of Houston College of Optometry, Houston, USA
    Ophthalmic Physiol Opt 33:379-84. 2013
  5. pmc Protective effects of high ambient lighting on the development of form-deprivation myopia in rhesus monkeys
    Earl L Smith
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 53:421-8. 2012
  6. ncbi request reprint Effects of brief periods of unrestricted vision on the development of form-deprivation myopia in monkeys
    Earl L Smith
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 43:291-9. 2002
  7. pmc Peripheral vision can influence eye growth and refractive development in infant monkeys
    Earl L Smith
    College of Optometry, University of Houston, TX 77204, USA
    Invest Ophthalmol Vis Sci 46:3965-72. 2005
  8. ncbi request reprint Continuous ambient lighting and lens compensation in infant monkeys
    Earl L Smith
    College of Optometry, University of Houston, Texas 77204 2020, USA
    Optom Vis Sci 80:374-82. 2003
  9. pmc Hemiretinal form deprivation: evidence for local control of eye growth and refractive development in infant monkeys
    Earl L Smith
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 50:5057-69. 2009
  10. pmc Relative peripheral hyperopic defocus alters central refractive development in infant monkeys
    Earl L Smith
    College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    Vision Res 49:2386-92. 2009

Research Grants

  1. OPTICALLY INDUCED ANISOMETROPIA
    Earl L Smith; Fiscal Year: 2010
  2. OPTICALLY INDUCED ANISOMETROPIA
    Earl Smith; Fiscal Year: 2005
  3. OPTICALLY INDUCED ANISOMETROPIA
    Earl Smith; Fiscal Year: 2007
  4. OPTICALLY INDUCED ANISOMETROPIA
    Earl Smith; Fiscal Year: 2007
  5. OPTICALLY INDUCED ANISOMETROPIA IN MONKEYS
    Earl Smith; Fiscal Year: 1993
  6. OPTICALLY INDUCED ANISOMETROPIA
    Earl Smith; Fiscal Year: 1999
  7. OPTICALLY INDUCED ANISOMETROPIA IN MONKEYS
    Earl Smith; Fiscal Year: 1991

Collaborators

Detail Information

Publications41

  1. pmc Wave aberrations in rhesus monkeys with vision-induced ametropias
    Ramkumar Ramamirtham
    College of Optometry, University of Houston, 505 J Davis Armistead Building, Houston, TX 77204 2020, USA
    Vision Res 47:2751-66. 2007
    ..The results from our study suggest that the higher amounts of wave aberrations observed in ametropic humans are likely to be a consequence, rather than a cause, of abnormal refractive development...
  2. pmc Optical treatment strategies to slow myopia progression: Effects of the visual extent of the optical treatment zone
    Earl L Smith
    College of Optometry, University of Houston, 505 J Davis Armistead Building, Houston, TX 77204 2020, USA Vision Cooperative Research Centre, Sydney, Australia Electronic address
    Exp Eye Res 114:77-88. 2013
    ....
  3. pmc Negative lens-induced myopia in infant monkeys: effects of high ambient lighting
    Earl L Smith
    College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    Invest Ophthalmol Vis Sci 54:2959-69. 2013
    ..To determine whether high light levels, which have a protective effect against form-deprivation myopia, also retard the development of lens-induced myopia in primates...
  4. doi request reprint Does peripheral retinal input explain the promising myopia control effects of corneal reshaping therapy (CRT or ortho-K) & multifocal soft contact lenses?
    Earl L Smith
    University of Houston College of Optometry, Houston, USA
    Ophthalmic Physiol Opt 33:379-84. 2013
    ..By their nature, views expressed in each section of the Point-Counterpoint article are those of the author concerned and may not reflect the views of all of the authors...
  5. pmc Protective effects of high ambient lighting on the development of form-deprivation myopia in rhesus monkeys
    Earl L Smith
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 53:421-8. 2012
    ..To test this hypothesis, the effects of high ambient lighting on vision-induced myopia in monkeys were determined...
  6. ncbi request reprint Effects of brief periods of unrestricted vision on the development of form-deprivation myopia in monkeys
    Earl L Smith
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 43:291-9. 2002
    ..To characterize the temporal integration properties of the mechanisms responsible for form-deprivation myopia (FDM), the effects of brief daily periods of unrestricted vision on the degree of FDM were investigated in infant monkeys...
  7. pmc Peripheral vision can influence eye growth and refractive development in infant monkeys
    Earl L Smith
    College of Optometry, University of Houston, TX 77204, USA
    Invest Ophthalmol Vis Sci 46:3965-72. 2005
    ..Given the prominence of central vision in humans, it has been assumed that visual signals from the fovea dominate emmetropization. The purpose of this study was to examine the impact of peripheral vision on emmetropization...
  8. ncbi request reprint Continuous ambient lighting and lens compensation in infant monkeys
    Earl L Smith
    College of Optometry, University of Houston, Texas 77204 2020, USA
    Optom Vis Sci 80:374-82. 2003
    ..To test this idea, we investigated the ability of infant monkeys reared with continuous light to compensate for optically imposed changes in refractive error...
  9. pmc Hemiretinal form deprivation: evidence for local control of eye growth and refractive development in infant monkeys
    Earl L Smith
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 50:5057-69. 2009
    ..To determine whether refractive development in primates is mediated by local retinal mechanisms, the authors examined the effects of hemiretinal form deprivation on ocular growth and the pattern of peripheral refractions in rhesus monkeys...
  10. pmc Relative peripheral hyperopic defocus alters central refractive development in infant monkeys
    Earl L Smith
    College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    Vision Res 49:2386-92. 2009
    ..These results show that peripheral refractive errors can have a substantial impact on central refractive development in primates...
  11. pmc Effects of foveal ablation on emmetropization and form-deprivation myopia
    Earl L Smith
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 48:3914-22. 2007
    ..To test this assumption, the authors determined whether an intact fovea was essential for either normal emmetropization or the vision-induced myopic errors produced by form deprivation...
  12. pmc Temporal constraints on experimental emmetropization in infant monkeys
    Chea su Kee
    College of Optometry, University of Houston, Houston, Texas, USA
    Invest Ophthalmol Vis Sci 48:957-62. 2007
    ..To characterize the temporal integration properties of the emmetropization process, the authors investigated the effects of brief daily interruptions of lens wear on the ocular compensation for negative lenses in infant rhesus monkeys...
  13. pmc Peripheral refraction in normal infant rhesus monkeys
    Li Fang Hung
    College of Optometry, University of Houston, Houston, Texas, USA
    Invest Ophthalmol Vis Sci 49:3747-57. 2008
    ..To characterize peripheral refractions in infant monkeys...
  14. pmc A comparison of refractive development between two subspecies of infant rhesus monkeys (Macaca mulatta)
    Ying Qiao-Grider
    College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    Vision Res 47:1668-81. 2007
    ..Substantial morphological and behavioral differences have been reported between Chinese- and Indian-derived subspecies. The purpose of this study was to compare refractive development in Chinese- and Indian-derived rhesus monkeys...
  15. ncbi request reprint Binocular deficits associated with early alternating monocular defocus. II. Neurophysiological observations
    Bin Zhang
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    J Neurophysiol 90:3012-23. 2003
    ....
  16. ncbi request reprint Recovery from form-deprivation myopia in rhesus monkeys
    Ying Qiao-Grider
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 45:3361-72. 2004
    ..The purpose of this investigation was to re-examine the ability of rhesus monkeys (Macaca mulatta) to recover from FDM...
  17. pmc Normal ocular development in young rhesus monkeys (Macaca mulatta)
    Ying Qiao-Grider
    College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    Vision Res 47:1424-44. 2007
    ..The purpose of this study was to characterize normal ocular development in infant monkeys and to establish both qualitative and quantitative relationships between human and monkey refractive development...
  18. ncbi request reprint Vitreal glutamate concentration in monkeys with experimental glaucoma
    Louvenia Carter-Dawson
    Department of Ophthalmology and Visual Science, University of Texas Houston Health Science Center, Houston, Texas 77030, USA
    Invest Ophthalmol Vis Sci 43:2633-7. 2002
    ..To investigate the hypothesis that the pathophysiology for the death of retinal ganglion cells in glaucoma involves excitotoxic effects from elevated concentrations of vitreal glutamate...
  19. ncbi request reprint Visual field defects and neural losses from experimental glaucoma
    Ronald S Harwerth
    College of Optometry, University of Houston, 505 J Davis Armistead Building, TX 77204 2020, USA
    Prog Retin Eye Res 21:91-125. 2002
    ..These experimental findings from glaucoma in monkeys provide fundamental data that should be applicable to improving methods for assessing glaucomatous optic neuropathy in patients...
  20. ncbi request reprint Temporal integration for stereoscopic vision
    Ronald S Harwerth
    College of Optometry, University of Houston, 505 J Davis Armistead Building, Houston, TX 77204 2020, USA
    Vision Res 43:505-17. 2003
    ..In addition, increased integration time does not account for the elevated stereothresholds of subjects with abnormal binocular vision...
  21. ncbi request reprint Binocular deficits associated with early alternating monocular defocus. I. Behavioral observations
    Janice M Wensveen
    University of Houston, College of Optometry, Houston, Texas 77204 2020, USA
    J Neurophysiol 90:3001-11. 2003
    ....
  22. ncbi request reprint Effects of optically imposed astigmatism on emmetropization in infant monkeys
    Chea su Kee
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 45:1647-59. 2004
    ..Although astigmatism is prevalent during early infancy, the influence of astigmatism on early refractive development is unclear. This study was undertaken to determine the effects of astigmatism on emmetropization in monkeys...
  23. pmc Effects of optical defocus on refractive development in monkeys: evidence for local, regionally selective mechanisms
    Earl L Smith
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 51:3864-73. 2010
    ..To characterize the influence of optical defocus on ocular shape and the pattern of peripheral refraction in infant rhesus monkeys...
  24. ncbi request reprint Glutathione content is altered in Müller cells of monkey eyes with experimental glaucoma
    Louvenia Carter-Dawson
    Department of Ophthalmology and Visual Science, University of Texas Houston Health Science Center, 6431 Fannin, Suite 7 024, Houston, TX 77030, USA
    Neurosci Lett 364:7-10. 2004
    ..The presence of more glutathione in Müller cells of glaucomatous retinas is consistent with an increase in extracellular glutamate and an increase in transport and metabolism of glutamate...
  25. ncbi request reprint The relationship between nerve fiber layer and perimetry measurements
    Ronald S Harwerth
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 48:763-73. 2007
    ....
  26. ncbi request reprint Scaling the structure--function relationship for clinical perimetry
    Ronald S Harwerth
    College of Optometry, University of Houston, Houston, Texas 77096 2020, USA
    Acta Ophthalmol Scand 83:448-55. 2005
    ..The present study was undertaken to compare linear and logarithmic transformations, which have been proposed for correlating the perimetric defects and neural losses of glaucoma...
  27. pmc Brief daily periods of unrestricted vision can prevent form-deprivation amblyopia
    Janice M Wensveen
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 47:2468-77. 2006
    ....
  28. ncbi request reprint Neural losses correlated with visual losses in clinical perimetry
    Ronald S Harwerth
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 45:3152-60. 2004
    ..The purpose of the present study was to investigate the neural and sensitivity losses from experimental glaucoma to establish the framework for a quantitative model for the structure-function relationships of standard clinical perimetry...
  29. pmc Astigmatism in monkeys with experimentally induced myopia or hyperopia
    Chea su Kee
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Optom Vis Sci 82:248-60. 2005
    ..This study examines the frequency and characteristics of astigmatism in infant monkeys that developed axial ametropias as a result of altered early visual experience...
  30. pmc Postnatal development of onset transient responses in macaque V1 AND V2 neurons
    Bin Zhang
    University of Houston, College of Optometry, Houston, TX, USA
    J Neurophysiol 100:1476-87. 2008
    ....
  31. ncbi request reprint Astigmatism in infant monkeys reared with cylindrical lenses
    Chea su Kee
    College of Optometry, University of Houston, 505 J Davis Armistead Building, Houston, TX 77204 2020, USA
    Vision Res 43:2721-39. 2003
    ..Our results indicate that visual experience can alter corneal shape, but there was no evidence that primates have an active, visually regulated "sphericalization" mechanism...
  32. ncbi request reprint Topographic map reorganization in cat area 17 after early monocular retinal lesions
    Kazuki Matsuura
    College of Optometry, University of Houston, TX 77204 2020, USA
    Vis Neurosci 19:85-96. 2002
    ....
  33. ncbi request reprint Prevalence of astigmatism in infant monkeys
    Chea su Kee
    College of Optometry, University of Houston, 505 J Davis Armistead Building, Houston, TX 7704 2020, USA
    Vision Res 42:1349-59. 2002
    ..In this study we examine the prevalence and nature of astigmatism in infant monkeys...
  34. ncbi request reprint Directional bias of neurons in V1 and V2 of strabismic monkeys: temporal-to-nasal asymmetry?
    Ichiro Watanabe
    College of Optometry, University of Houston, TX 77204, USA
    Invest Ophthalmol Vis Sci 46:3899-905. 2005
    ..In the current study, the hypothesis that this eye movement anomaly reflects a similar asymmetry in the directional response properties of neurons in the early stages of cortical processing was examined...
  35. pmc Monochromatic ocular wave aberrations in young monkeys
    Ramkumar Ramamirtham
    College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    Vision Res 46:3616-33. 2006
    ....
  36. ncbi request reprint Effects of the duration of early strabismus on the binocular responses of neurons in the monkey visual cortex (V1)
    Takafumi Mori
    College of Optometry, University of Houston, Houston, Texas 77204 2020, USA
    Invest Ophthalmol Vis Sci 43:1262-9. 2002
    ..To determine how the duration of early strabismus influences the severity of loss of disparity sensitivity in V1 neurons and the effects of extensive poststrabismus visual experience on the maintenance of functional binocular connections...
  37. ncbi request reprint Adaptive optics scanning laser ophthalmoscopy for in vivo imaging of lamina cribrosa
    Abhiram S Vilupuru
    College of Optometry, University of Houston, TX 77204 2020, USA
    J Opt Soc Am A Opt Image Sci Vis 24:1417-25. 2007
    ..The AOSLO provides high-quality images of the lamina cribrosa and may have potential as a tool for early identification of glaucoma...
  38. pmc Delayed maturation of receptive field center/surround mechanisms in V2
    Bin Zhang
    College of Optometry, University of Houston, Houston, TX 77204 2020, USA
    Proc Natl Acad Sci U S A 102:5862-7. 2005
    ....
  39. pmc Rapid plasticity of binocular connections in developing monkey visual cortex (V1)
    Bin Zhang
    College of Optometry, University of Houston, 505 J Davis Armistead Building, Houston, TX 77204 2020, USA
    Proc Natl Acad Sci U S A 102:9026-31. 2005
    ....
  40. ncbi request reprint Image defocus modulates activity of bipolar and amacrine cells in macaque retina
    Xingwu Zhong
    Department of Cell Biology and Anatomy, Neuroscience Research Group and Lions Sight Centre, University of Calgary Faculty of Medicine, Alberta, Canada
    Invest Ophthalmol Vis Sci 45:2065-74. 2004
    ..Focus-sensitive retinal neurons were labeled with immunocytochemical markers after briefly altering image quality in infant monkeys...
  41. ncbi request reprint Compensation for experimentally induced hyperopic anisometropia in adolescent monkeys
    Xingwu Zhong
    Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou, Peoples Republic of China
    Invest Ophthalmol Vis Sci 45:3373-9. 2004
    ..The purpose of this study was to determine whether chronic optical defocus alters refractive development in monkeys at ages corresponding to when myopia typically develops in children...

Research Grants30

  1. OPTICALLY INDUCED ANISOMETROPIA
    Earl L Smith; Fiscal Year: 2010
    ..The results of these studies will potentially provide the foundation for new treatment and management strategies for human refractive errors. ..
  2. OPTICALLY INDUCED ANISOMETROPIA
    Earl Smith; Fiscal Year: 2005
    ..Moreover, these investigation will help determine the extent to which refractive errors need to be corrected in young infants in order to avoid the development of sensory disorders. ..
  3. OPTICALLY INDUCED ANISOMETROPIA
    Earl Smith; Fiscal Year: 2007
    ..The results of these studies will potentially provide the foundation for new treatment and management strategies for human refractive errors. ..
  4. OPTICALLY INDUCED ANISOMETROPIA
    Earl Smith; Fiscal Year: 2007
    ..The results of these studies will potentially provide the foundation for new treatment and management strategies for human refractive errors. ..
  5. OPTICALLY INDUCED ANISOMETROPIA IN MONKEYS
    Earl Smith; Fiscal Year: 1993
    ....
  6. OPTICALLY INDUCED ANISOMETROPIA
    Earl Smith; Fiscal Year: 1999
    ..Moreover, these investigation will help determine the extent to which refractive errors need to be corrected in young infants in order to avoid the development of sensory disorders. ..
  7. OPTICALLY INDUCED ANISOMETROPIA IN MONKEYS
    Earl Smith; Fiscal Year: 1991
    ....