Research Topics
Species | Marc C SmaldoneSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Resection of recurrent inferior vena cava tumor after radical nephrectomy for renal cell carcinomaMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Urology 67:1084.e5-7. 2006..Although technically difficult, repeat resection of IVC tumor recurrence after nephrectomy for renal cell carcinoma is an acceptable method of treatment...
Contemporary surgical management of pediatric urolithiasisMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 3232, USA
Urol Clin North Am 37:253-67. 2010..Randomized controlled trials comparing the efficacy of SWL and URS for upper tract stone burdens are needed to reach consensus regarding the most effective primary treatment modality in children...
Laparoscopic nephrectomy using the EnSeal Tissue Sealing and Hemostasis System: successful therapeutic application of nanotechnologyMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
JSLS 12:213-6. 2008..We report our initial experience using the EnSeal Tissue Sealing and Hemostasis System during laparoscopic nephrectomy and discuss its potential advantages and disadvantages compared with those of contemporary technologies...
Muscle derived stem cell therapy for stress urinary incontinenceMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, 3471 5th Avenue, Suite 700, Pittsburgh, PA 15213 3232, USA
World J Urol 26:327-32. 2008..The aim of this article is to discuss the potential of muscle-derived stem cells (MDSCs) for rhabdosphincter regeneration and to review the early clinical experiences with its application in patients with stress urinary incontinence...
Long-term results of selective partial cystectomy for invasive urothelial bladder carcinomaMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Urology 72:613-6. 2008..We reviewed our experience with partial cystectomy to assess local control and survival rates, and to identify pathologic predictors for recurrence...
Strategies to enhance the efficacy of intravescical therapy for non-muscle invasive bladder cancerM C Smaldone
Department of Urology, University of Pittsburgh School of Medicine Pittsburgh, PA 15213, USA
Minerva Urol Nefrol 61:71-89. 2009..Our aim in this report is to provide a comprehensive review of contemporary intravesical therapy options for NMIBC with an emphasis on emerging agents and novel treatment modalities...
Investigational therapies for non-muscle invasive bladder cancerMarc C Smaldone
University of Pittsburgh Medical Center, Department of Urology, Kaufmann Building, 3471 5th Avenue, Pittsburgh, PA 15213, USA
Expert Opin Investig Drugs 19:371-83. 2010..However, recurrence rates as high as 30% and significant local/systemic toxicity have resulted in an increased interest in the use of alternative intravesical agents...
Percutaneous resection of upper tract transitional cell carcinoma in a solitary kidney after cystectomy and continent orthotopic urinary diversionMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Endourol 22:2087-9; discussion 2095. 2008
Estimating postoperative mortality and morbidity risk of radical cystectomy with continent diversion using predictor equationsMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15232, USA
J Urol 182:2619-24. 2009..We tested the validity of POSSUM and Portsmouth POSSUM in patients undergoing radical cystectomy with continent diversion...
Is ureteroscopy first line treatment for pediatric stone disease?Marc C Smaldone
Division of Pediatric Urology, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213 3232, USA
J Urol 178:2128-31; discussion 2131. 2007..We report our current outcomes for ureteroscopic management of pediatric stone disease...
Giant idiopathic renal arteriovenous fistula requiring urgent nephrectomyMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213 3232, USA
Urology 69:576.e1-3. 2007..Gross hematuria resulted from AVF erosion into the collecting system. Given the size of the AVF, endovascular coil embolization was attempted but deemed too risky, necessitating urgent nephrectomy...
Complete ureteral stent encrustation managed with serial nephroscopy and laser lithotripsyJoseph L Whetstone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Urology 69:576.e15-6. 2007..We present a case of a 2800-mm2 stent encrustation managed with serial nephroscopy and laser lithotripsy...
Advances in pediatric urologic laparoscopyM C Smaldone
Division of Pediatric Urology, Children s Hospital of Pittsburgh, Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
ScientificWorldJournal 7:727-41. 2007..This report will provide a directed review of the literature to establish the current indications for laparoscopy in pediatric urologic surgery...
Laparoscopy in paediatric urology: present statusMarc C Smaldone
Urology, University of Pittsburgh Medical Center, 3471 5th Avenue, Pittsburgh, PA 15213, USA
BJU Int 100:143-50. 2007..The initial experiences with laparoscopic ureteric re-implantation and laparoscopically assisted bladder reconstructive surgery are reported, with encouraging results for feasibility, hospital stay, and cosmetic outcome...
Neuromodulation versus neurotoxin for the treatment of refractory detrusor overactivity: for neurotoxinMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Suite 700, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
Nat Clin Pract Urol 5:120-1. 2008
Ureteroscopic management of lower-pole stones in a pediatric populationGlenn M Cannon
Department of Urology, Children s Hospital, Boston, Boston, Massachusetts 02115, USA
J Endourol 21:1179-82. 2007..We report our experience with ureteroscopy to treat lower-pole calculi in children...
When is prior ureteral stent placement necessary to access the upper urinary tract in prepubertal children?Anthony T Corcoran
Division of Pediatric Urology, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213 3232, USA
J Urol 180:1861-3; discussion 1863-4. 2008..We studied the possibility that age, height, weight and body mass index could be used to predict the likelihood of successful ureteroscopic access to the upper urinary tract without previous stent placement in prepubertal children...
Cloacal exstrophy variant with intravesical phallus: further description of anatomy and implications for gender reassignmentJeffrey J Tomaszewski
Division of Pediatric Urology, Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
J Pediatr Urol 8:426-30. 2012....
Increased nerve growth factor in neurogenic overactive bladder and interstitial cystitis patientsBruce L Jacobs
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Can J Urol 17:4989-94. 2010..We evaluated urine nerve growth factor (NGF) levels from patients with a variety of urologic conditions to examine NGF's role as a future biomarker...
Computerized tomography findings in pediatric renal trauma--indications for early intervention?Glenn M Cannon
Division of Pediatric Urology, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Urol 179:1529-32; discussion 1532-3. 2008..We sought to determine if initial computerized tomography findings in pediatric patients suffering blunt renal trauma with urinary extravasation were predictive of the need for operative intervention...
Robotic-assisted laparoscopic extravesical ureteroneocystostomy for management of adult ureteral duplication with upper pole prostatic urethral insertionJeffrey A Larson
Department of Urology, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
JSLS 13:458-61. 2009..Clinical follow-up and repeat imaging documented symptomatic and radiographic improvement. Robotic-assisted laparoscopic reconstructive techniques are feasible and efficacious in the management of adult ureteral anomalies...
Staged retrograde endoscopic lithotripsy as alternative to PCNL in select patients with large renal calculiDaniel J Ricchiuti
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
J Endourol 21:1421-4. 2007..In a selected group of patients who were not ideal candidates for PCNL because of extenuating health factors, a staged retrograde endoscopic approach was used to manage upper urinary tract calculi...
Cesium 131 versus iodine 125 implants for prostate cancer: evaluation of early PSA responseJeffrey J Tomaszewski
Department of Urology, University of Pittsburgh School of Medicine, Pennsylvania, USA
Can J Urol 17:5360-4. 2010..We compare initial PSA outcomes in men undergoing Cs-131 prostate brachytherapy to men treated with I-125...
Endourological management of pediatric stone disease: present statusMarc C Smaldone
Division of Pediatric Urology, Children s Hospital of Pittsburgh, Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
J Urol 181:17-28. 2009..We reviewed the current status of pediatric stone disease management...
Effect of skin-to-stone distance on shockwave lithotripsy successBruce L Jacobs
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Endourol 22:1623-7. 2008..We evaluated the effect of increased body habitus on stone-free rates after shockwave lithotripsy (SWL), determined by three reproducible skin-to-stone distances (SSDs) on CT...
Factors affecting blood loss during percutaneous nephrolithotomy using balloon dilation in a large contemporary seriesJeffrey J Tomaszewski
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Endourol 24:207-11. 2010..We review factors affecting blood loss and transfusion requirements in a large contemporary series of patients undergoing PNL utilizing balloon dilation...
Renal access by urologist or radiologist during percutaneous nephrolithotomyJeffrey J Tomaszewski
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Endourol 24:1733-7. 2010..We evaluated percutaneous access for percutaneous nephrolithotomy (PCNL) that was obtained by interventional radiologists or urologists at a single academic institution and compared access outcomes and complications...
Outcomes of percutaneous nephrolithotomy stratified by body mass indexJeffrey J Tomaszewski
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Endourol 24:547-50. 2010..Obesity places surgical patients at a greater risk of complications. The effects of obesity on outcomes and complications from percutaneous nephrolithotomy (PCNL) are not well defined...
The application of endoscopic techniques in the management of upper tract recurrence after cystectomy and urinary diversionJeffrey J Tomaszewski
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Endourol 23:1265-72. 2009....
Eligibility for active surveillance and pathological outcomes for men undergoing radical prostatectomy in a large, community based cohortMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
J Urol 183:138-43. 2010..We analyzed competing active surveillance criteria in men who underwent radical prostatectomy in relation to outcome data in a large, community based cohort...
Multiplex analysis of urinary cytokine levels in rat model of cyclophosphamide-induced cystitisMarc C Smaldone
Department of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Urology 73:421-6. 2009..In the present study, we subjected rat urine to multiplex cytokine analysis in an attempt to identify an inflammatory signature of the temporal course of cyclophosphamide (CYP)-induced cystitis...
Minimally invasive treatment of vesicoureteral refluxMatthew H Hayn
Department of Urology, University of Pittsburgh Medical Center, Kaufmann Medical Building, Suite 700, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
Urol Clin North Am 35:477-88, ix. 2008..This article reviews the endoscopic materials, techniques, and outcomes in the treatment of VUR in addition to the techniques and outcomes of laparoscopic and robotic ureteroneocystotomy...
Minimally invasive surgery for urologic disease in childrenDanielle D Sweeney
University of Pittsburgh Medical Center, USA
Nat Clin Pract Urol 4:26-38. 2007..It is our hope that minimally invasive surgical approaches to urologic conditions will become available to all children and become commonplace at most institutions...
Management of Bladder Cancer following Solid Organ TransplantationJeffrey J Tomaszewski
Department of Urology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Adv Urol 2011:256985. 2011..Conclusions. Bladder cancer is uncommon following renal and liver transplantation, but it can be managed successfully with local and/or extirpative therapy. The use of intravesical BCG is possible in select immunosuppressed patients...
Natural orifice transluminal endoscopic surgery (NOTES): current experience and urologic applicationsDaniel P Casella
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Can J Urol 17:5151-61. 2010..Our aim is to evaluate NOTES techniques, portals of entry, early clinical experiences, and the application of NOTES to urologic surgery...
Management of benign ureteral strictures in the endoscopic eraAnthony T Corcoran
Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
J Endourol 23:1909-12. 2009..We reviewed our experience with the management of benign ureteral strictures to determine the success rate of endoscopic surgery in a contemporary series and assessed the viability of surgical reimplantation in the modern era...
Percutaneous nephrolithotomy in childrenTina K Schuster
Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
J Endourol 23:1699-705. 2009..To review the history of percutaneous nephrolithotomy (PCNL) in children, describe technical considerations, including advancements in equipment, and discuss future directions...
Conservative management of synchronous bilateral blunt renal injuriesBruce L Jacobs
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213 3232, USA
Can J Urol 15:4115-7. 2008..This case demonstrates that in select cases bilateral renal injuries can be managed conservatively...
Bladder diverticulum arising adjacent to an ectopic ureter presenting as a cystic massBrett Michelotti
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Can J Urol 15:4024-6. 2008..The patient underwent a transurethral resection of the prostate to reduce his bladder outlet obstruction, and subsequently underwent an open diverticulectomy...
Delayed presentation of iliopsoas abscess from ureterosigmoidostomy stump fistulization 30 years following nephrectomyLei Chu
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Can J Urol 15:4273-5. 2008..After percutaneous drainage of the abscess and intravenous antibiotic therapy, the patient was managed with complete excision of the ureterosigmoid anastomoses and creation of an ileal conduit urinary diversion...
Validation of the Fournier's gangrene severity index in a large contemporary seriesA T Corcoran
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Urol 180:944-8. 2008..In this study we identified prognostic factors for survival and validated the accuracy of the Fournier's gangrene severity index in patients with Fournier's gangrene...
Real-time tomographic reflection in facilitating percutaneous access to the renal collecting systemMang L Chen
Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
J Endourol 25:743-5. 2011..It may therefore facilitate invasive procedures, such as percutaneous access to the kidney. This proof-of-concept study assesses the feasibility of this technique for renal imaging and concomitant needle puncture guidance...
Prostate brachytherapy after ileal pouch-anal anastomosis reconstructionRichard Williamson
Department of Urology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Urology 73:369-73. 2009..To determine the safety of prostate brachytherapy in patients with clinically localized prostate cancer who have undergone proctocolectomy with ileal pouch-anal anastomosis (IPAA)...
The impact of obesity on overall and cancer specific survival in men with prostate cancerBenjamin J Davies
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15232, USA
J Urol 182:112-7; discussion 117. 2009..We examined the impact of obesity on disease specific and overall survival in patients with prostate cancer...
Role of tumor location in selecting patients for percutaneous versus surgical cryoablation of renal massesChristopher J Long
Department of Urology, Temple University Hospital, Philadelphia, Pennsylvania, USA
Can J Urol 19:6417-22. 2012..To characterize the relationship between tumor location and choice in selecting surgical cryoablation (SCA) versus percutaneous cryoablation (PCA) for treatment of renal masses...
The evolution of the endourologic management of pediatric stone diseaseMarc C Smaldone
Division of Pediatric Urology, Children s Hospital of Pittsburgh, Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Indian J Urol 25:302-11. 2009..This report provides a comprehensive review of the literature evaluating the indications, techniques, complications, and efficacy of endourologic stone management in children...
Inguinal canal recurrence of colorectal adenocarcinoma following cytoreductive surgery and intraperitoneal hyperthermic chemotherapyJeffrey J Tomaszewski
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Can J Urol 15:4428-30. 2008..When communicating with the peritoneal cavity, the inguinal canal may act as an anatomic sanctuary site and allow peritoneal carcinomatosis to escape the effects of intraperitoneal chemotherapy...
Differential expression of functional cannabinoid receptors in human bladder detrusor and urotheliumVikas Tyagi
Department of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania
J Urol 181:1932-8. 2009..Consequently we investigated the expression of functional cannabinoid 1 and 2 receptors in human bladder detrusor and urothelium...
Clinical implications of hypoxia inducible factor in renal cell carcinomaMarc C Smaldone
Department of Urology, University of Pittsburgh Medical Center and University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA
Urol Oncol 27:238-45. 2009..This report provides a directed review of recent discoveries defining the role of HIF in renal tumorigenesis and their relevance to the clinical advances in targeted therapy for advanced RCC...
The gatekeeper disparity--why do some medical schools send more medical students into urology?Alexander Kutikov
Division of Urological Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
J Urol 185:647-52. 2011..We evaluated the reasons why some medical schools consistently send more students into urology than others...
Stuttering priapism associated with hereditary spherocytosisKarti Prabhakaran
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213 3232, USA
Can J Urol 14:3702-4. 2007..We present a case of stuttering priapism in a 44 year-old male with hereditary spherocytosis and discuss the pathophysiology and clinical management of this entity...
Botulinum toxin therapy for neurogenic detrusor overactivityMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Suite 700, Kaufmann Building, 3471 5th Avenue, Pittsburgh, PA 15213, USA
Urol Clin North Am 37:567-80. 2010..The objective of this review is to provide a focused summary of the current body of literature, investigating the safety and efficacy of bladder BTX injection in patients with NDO...
Prolonged natural progression from localized to symptomatic renal cell carcinomaSteve Sterious
Department of Surgucal Oncology, Division of Urological Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Can J Urol 19:6578-80. 2012..We present a case of a localized, clinical stage T2 renal mass progressing to regional and systemic disease over 6 years, demonstrating that kinetics of disease progression may be prolonged and are yet to be fully understood...
Extended-spectrum beta-lactamase gram-negative sepsis following prostate biopsy: implications for use of fluoroquinolone prophylaxisGlenn M Cannon
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Can J Urol 14:3653-5. 2007..The patient recovered with intravenous ertapenem. Fluoroquinolone resistant bacteria are increasing in prevalence. This needs to be recognized when the antibiotic choice for pre-procedure prophylaxis is made...
Paratesticular rhabdomyoma in a young adult: case study and review of the literatureBenjamin Davies
Division of Pediatric Urology, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
J Pediatr Surg 42:E5-7. 2007..We report the first case of a locally invasive paratesticular rhabdomyoma in a 17-year-old male teenager who presented with chronic scrotal pain. We further review the current literature of this rare tumor...
Immunosuppressive preconditioning or induction regimens : evidence to dateHenkie P Tan
Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Drugs 66:1535-45. 2006..The different therapeutic preconditioning or induction agents and their associated effects on cellular rejection, graft survival outcomes and the need for multiagent post-transplant maintenance therapy are reviewed...
Case report: bilateral ureteral obstruction secondary to Aspergillus bezoarMarc C Smaldone
Department of Urology, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
J Endourol 20:318-20. 2006..The left-sided obstruction resolved with antifungal therapy. However, her right ureteral obstruction persisted and was managed with ureteroscopy and removal of the fungal bezoar...
Drainage characteristics and differential function of the horseshoe kidney: what is typical?Benjamin R Stockton
Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
J Endourol 22:1175-7. 2008..To describe the drainage and differential function of the horseshoe kidney...
Safety and efficacy of flexible ureterorenoscopy and holmium:YAG lithotripsy for intrarenal stones in anticoagulated casesBurak Turna
Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
J Urol 179:1415-9. 2008..We compared perioperative outcomes in patients undergoing ureterorenoscopy and Ho:YAG lithotripsy for renal calculi with or without anticoagulation...
