E P Sloan

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint The use of the Revised Trauma Score as an entry criterion in traumatic hemorrhagic shock studies: data from the DCLHb clinical trials
    Edward P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, Illinois 60612, USA
    Prehosp Disaster Med 27:330-44. 2012
  2. ncbi request reprint The lack of consistent diaspirin cross-linked hemoglobin infusion blood pressure effects in the US and EU traumatic hemorrhagic shock clinical trials
    Edward P Sloan
    Department of Emergency Medicine, College of Medicine, Chicago, IL 60612, USA
    Shock 33:123-33. 2010
  3. ncbi request reprint Post hoc mortality analysis of the efficacy trial of diaspirin cross-linked hemoglobin in the treatment of severe traumatic hemorrhagic shock
    Edward P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, 60612, USA
    J Trauma 52:887-95. 2002
  4. ncbi request reprint Prehospital trauma research methodology
    Edward P Sloan
    Department of Emergency Medicine, University of Illinois College of Medicine, Chicago 60612, USA
    Prehosp Emerg Care 6:S68-74. 2002
  5. doi request reprint Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation
    Edward P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Trauma 68:1158-71. 2010
  6. ncbi request reprint A proposed consent process in studies that use an exception to informed consent
    E P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, 60612, USA
    Acad Emerg Med 6:1283-91. 1999
  7. ncbi request reprint The informed consent process and the use of the exception to informed consent in the clinical trial of diaspirin cross-linked hemoglobin (DCLHb) in severe traumatic hemorrhagic shock. DCLHb Traumatic Hemorrhagic Shock study group
    E P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, USA
    Acad Emerg Med 6:1203-9. 1999
  8. ncbi request reprint Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock: a randomized controlled efficacy trial
    E P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, 60612, USA
    JAMA 282:1857-64. 1999
  9. ncbi request reprint The emergency department electrocardiogram and hospital complications in myocardial infarction patients
    R J Zalenski
    Center for Health Services Research, University of Illinois at Chicago 60612 7260, USA
    Acad Emerg Med 3:318-25. 1996
  10. ncbi request reprint Comparison of the New Injury Severity Score and the Injury Severity Score
    Seow Yian Tay
    Department of Emergency Medicine, University of Illinois at Chicago, USA
    J Trauma 56:162-4. 2004

Detail Information

Publications16

  1. ncbi request reprint The use of the Revised Trauma Score as an entry criterion in traumatic hemorrhagic shock studies: data from the DCLHb clinical trials
    Edward P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, Illinois 60612, USA
    Prehosp Disaster Med 27:330-44. 2012
    ..99, 2-4.99, 1-4.99, and 2-5.99) identifies patients with predicted and actual mortality rates near 50% for use as an entry criterion in traumatic hemorrhagic shock clinical trials...
  2. ncbi request reprint The lack of consistent diaspirin cross-linked hemoglobin infusion blood pressure effects in the US and EU traumatic hemorrhagic shock clinical trials
    Edward P Sloan
    Department of Emergency Medicine, College of Medicine, Chicago, IL 60612, USA
    Shock 33:123-33. 2010
    ..As such, no clinically demonstrable DCLHb pressor effect could be directly related to the adverse mortality outcome observed in the US study...
  3. ncbi request reprint Post hoc mortality analysis of the efficacy trial of diaspirin cross-linked hemoglobin in the treatment of severe traumatic hemorrhagic shock
    Edward P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, 60612, USA
    J Trauma 52:887-95. 2002
    ..The efficacy trial of diaspirin cross-linked hemoglobin (DCLHb) in traumatic hemorrhagic shock demonstrated an unexpected mortality imbalance, prompting a three-step review to better understand the cause of this finding...
  4. ncbi request reprint Prehospital trauma research methodology
    Edward P Sloan
    Department of Emergency Medicine, University of Illinois College of Medicine, Chicago 60612, USA
    Prehosp Emerg Care 6:S68-74. 2002
  5. doi request reprint Diaspirin cross-linked hemoglobin infusion did not influence base deficit and lactic acid levels in two clinical trials of traumatic hemorrhagic shock patient resuscitation
    Edward P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Trauma 68:1158-71. 2010
    ..Diaspirin cross-linked hemoglobin (DCLHb) has demonstrated a pressor effect that could adversely affect traumatic hemorrhagic shock patients through diminished perfusion to vital organs, causing base deficit (BD) and lactate abnormalities...
  6. ncbi request reprint A proposed consent process in studies that use an exception to informed consent
    E P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, 60612, USA
    Acad Emerg Med 6:1283-91. 1999
    ..Multiple mechanisms exist that allow for consent to be provided or declined, both prior to and after enrollment in the research protocol. The ongoing immediate review of the process allows for process enhancements to be made as needed...
  7. ncbi request reprint The informed consent process and the use of the exception to informed consent in the clinical trial of diaspirin cross-linked hemoglobin (DCLHb) in severe traumatic hemorrhagic shock. DCLHb Traumatic Hemorrhagic Shock study group
    E P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, USA
    Acad Emerg Med 6:1203-9. 1999
    ..When it was not feasible to obtain prospective consent, an exception to informed consent was used according to FDA regulation 21 CFR 50.24...
  8. ncbi request reprint Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock: a randomized controlled efficacy trial
    E P Sloan
    Department of Emergency Medicine, University of Illinois at Chicago, 60612, USA
    JAMA 282:1857-64. 1999
    ..Severe, uncompensated, traumatic hemorrhagic shock causes significant morbidity and mortality, but resuscitation with an oxygen-carrying fluid might improve patient outcomes...
  9. ncbi request reprint The emergency department electrocardiogram and hospital complications in myocardial infarction patients
    R J Zalenski
    Center for Health Services Research, University of Illinois at Chicago 60612 7260, USA
    Acad Emerg Med 3:318-25. 1996
    ..To determine whether acute myocardial infarction (AMI) patients who have negative ECGs on presentation have significantly lower complication rates than do those AMI patients who have positive ECGs on presentation...
  10. ncbi request reprint Comparison of the New Injury Severity Score and the Injury Severity Score
    Seow Yian Tay
    Department of Emergency Medicine, University of Illinois at Chicago, USA
    J Trauma 56:162-4. 2004
    ..The New Injury Severity Score (NISS) was proposed in 1997 to replace the Injury Severity Score (ISS) because it is more sensitive for mortality. We aim to test whether this is true in our patients...
  11. ncbi request reprint Aminophylline in the treatment of acute asthma when beta 2-adrenergics and steroids are provided
    D G Murphy
    Department of Emergency Medicine, Cook County Hospital, Chicago
    Arch Intern Med 153:1784-8. 1993
    ..05). CONCLUSION: In the emergency department setting, aminophylline contributes no significant improvement in PEFR when beta 2-agonists and corticosteroids are being provided, while causing more side effects...
  12. ncbi request reprint Setting-based practice variation in the management of simple febrile seizure
    L C Hampers
    Children s Memorial Hospital, Chicago, IL, USA
    Acad Emerg Med 7:21-7. 2000
    ..To identify provider-based differences in the ED assessment and management of children presenting with uncomplicated, first-time febrile seizures...
  13. ncbi request reprint Documentation of ED patient pain by nurses and physicians
    Stephen C Eder
    Department of Emergency Medicine, University of Illinois College of Medicine, 808 South Wood Street, Chicago, IL 60612, USA
    Am J Emerg Med 21:253-7. 2003
    ..Patients with severe pain and those receiving powerful analgesics were more likely to have a pain assessment subsequent to ED therapy...
  14. ncbi request reprint Myocardial infarction and cardiac complications in emergency department patients admitted to the intensive care unit with gastrointestinal hemorrhage
    Heather M Prendergast
    Department of Emergency Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Emerg Med 28:19-25. 2005
    ..Younger patients presenting with hematemesis and a history of significant alcohol use tended to have fewer complications such that it may be possible to manage these patients outside of the ICU if hemodynamically stable...
  15. ncbi request reprint The clinical trials of diaspirin cross-linked hemoglobin (DCLHb) in severe traumatic hemorrhagic shock: the tale of two continents
    Edward P Sloan
    Intensive Care Med 29:347-9. 2003
  16. ncbi request reprint Post hoc mortality analysis on the efficacy trial of diaspirin cross-linked hemoglobin in the treatment of severe traumatic hemorrhagic shock
    C Gillon Ward
    J Trauma 53:1031; author reply 1031-2. 2002