M L Slattery

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. ncbi request reprint Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer
    Martha L Slattery
    Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
    Int J Cancer 120:656-63. 2007
  2. ncbi request reprint Plant foods, fiber, and rectal cancer
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, and the Kaiser Permanente Medical Research Program, Oakland, CA, USA
    Am J Clin Nutr 79:274-81. 2004
  3. ncbi request reprint Physical activity and colorectal cancer
    M L Slattery
    Health Research Center, University of Utah, Salt Lake City 84108, USA
    Am J Epidemiol 158:214-24. 2003
  4. ncbi request reprint PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States)
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, 84108, USA
    Cancer Causes Control 17:239-49. 2006
  5. ncbi request reprint Lifestyle factors and Ki-ras mutations in colon cancer tumors
    M L Slattery
    Health Research Centre, Department of Family and Preventive Medicine, 375 Chipeta Way, Suite A, University of Utah, Salt Lake City, UT 84108, USA
    Mutat Res 483:73-81. 2001
  6. ncbi request reprint Genetic variation in IGF1, IGFBP3, IRS1, IRS2 and risk of breast cancer in women living in Southwestern United States
    M L Slattery
    University of Utah, Salt Lake City, Utah 84108, USA
    Breast Cancer Res Treat 104:197-209. 2007
  7. ncbi request reprint ESR1, AR, body size, and breast cancer risk in Hispanic and non-Hispanic white women living in the Southwestern United States
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84117, USA
    Breast Cancer Res Treat 105:327-35. 2007
  8. ncbi request reprint Trans-fatty acids and colon cancer
    M L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Nutr Cancer 39:170-5. 2001
  9. ncbi request reprint Associations between family history of colorectal cancer and genetic alterations in tumors
    Martha L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA
    Int J Cancer 97:823-7. 2002
  10. ncbi request reprint Leptin and colorectal cancer: an undefined link
    Martha L Slattery
    University of Utah School of Medicine, Suite A, 375 Chipeta Way, Salt Lake City, UT 84108, USA
    Nat Clin Pract Gastroenterol Hepatol 4:118-9. 2007

Collaborators

Detail Information

Publications107 found, 100 shown here

  1. ncbi request reprint Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer
    Martha L Slattery
    Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
    Int J Cancer 120:656-63. 2007
    ..Our data suggest multiple pathways to colon cancer. They do not support a unique role for dietary folate, alcohol, vitamins B(6) and B(12) and methionine in a CpG island methylator phenotype...
  2. ncbi request reprint Plant foods, fiber, and rectal cancer
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, and the Kaiser Permanente Medical Research Program, Oakland, CA, USA
    Am J Clin Nutr 79:274-81. 2004
    ..Associations between colon and rectal cancer and intakes of vegetables, other plant foods, and fiber have stimulated much debate...
  3. ncbi request reprint Physical activity and colorectal cancer
    M L Slattery
    Health Research Center, University of Utah, Salt Lake City 84108, USA
    Am J Epidemiol 158:214-24. 2003
    ..39, 0.78 for men; OR = 0.44, 95% CI: 0.30, 0.67 for women). In summary, physical activity was associated with reduced risk of rectal cancer in these data. The reduced risk was similar to that previously observed for colon cancer...
  4. ncbi request reprint PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States)
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, 84108, USA
    Cancer Causes Control 17:239-49. 2006
    ..These data suggest that PPARgamma may be associated with many aspects of colorectal cancer including insulin- and inflammation-related mechanisms...
  5. ncbi request reprint Lifestyle factors and Ki-ras mutations in colon cancer tumors
    M L Slattery
    Health Research Centre, Department of Family and Preventive Medicine, 375 Chipeta Way, Suite A, University of Utah, Salt Lake City, UT 84108, USA
    Mutat Res 483:73-81. 2001
    ..Given the limited information available on what causes Ki-ras mutations, the information generated from this study indicates that these factors previously associated with colon cancer work through other disease pathways...
  6. ncbi request reprint Genetic variation in IGF1, IGFBP3, IRS1, IRS2 and risk of breast cancer in women living in Southwestern United States
    M L Slattery
    University of Utah, Salt Lake City, Utah 84108, USA
    Breast Cancer Res Treat 104:197-209. 2007
    ..An insulin-related pathway to breast cancer has been hypothesized...
  7. ncbi request reprint ESR1, AR, body size, and breast cancer risk in Hispanic and non-Hispanic white women living in the Southwestern United States
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84117, USA
    Breast Cancer Res Treat 105:327-35. 2007
    ..02 and <0.01 respectively). These results suggest differences in risk factors for NHW and Hispanic women. However, they provide only minor support for the role of the AR and ESR1 gene in the etiology of breast cancer...
  8. ncbi request reprint Trans-fatty acids and colon cancer
    M L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Nutr Cancer 39:170-5. 2001
    ..It seems prudent to avoid consuming partially hydrogenated fats, since no increased risk was observed for the cis form of fatty acids, while suggestions of increased risk from trans-fatty acids exist for subsets of the population...
  9. ncbi request reprint Associations between family history of colorectal cancer and genetic alterations in tumors
    Martha L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA
    Int J Cancer 97:823-7. 2002
    ....
  10. ncbi request reprint Leptin and colorectal cancer: an undefined link
    Martha L Slattery
    University of Utah School of Medicine, Suite A, 375 Chipeta Way, Salt Lake City, UT 84108, USA
    Nat Clin Pract Gastroenterol Hepatol 4:118-9. 2007
  11. ncbi request reprint Physical activity and colon cancer: confounding or interaction?
    Martha L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City 84108, USA
    Med Sci Sports Exerc 34:913-9. 2002
    ..Confounding and effect modification are examined to better understand the physical activity and colon cancer association...
  12. ncbi request reprint Body size, weight change, fat distribution and breast cancer risk in Hispanic and non-Hispanic white women
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84117, USA
    Breast Cancer Res Treat 102:85-101. 2007
    ..The incidence of breast cancer varies among women living in the Southwestern part of the US. We evaluate how body size influences breast cancer risk among these women...
  13. ncbi request reprint PPARgamma, energy balance, and associations with colon and rectal cancer
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City 84108, USA
    Nutr Cancer 51:155-61. 2005
    ..These data do not support the hypothesis that the P12A PPARgamma polymorphism is associated with colon or rectal cancer through regulation of energy balance...
  14. ncbi request reprint Factors associated with colorectal cancer screening in a population-based study: the impact of gender, health care source, and time
    M L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake, UT 84108, USA
    Prev Med 38:276-83. 2004
    ....
  15. ncbi request reprint Associations between apoE genotype and colon and rectal cancer
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84108, USA
    Carcinogenesis 26:1422-9. 2005
    ....
  16. ncbi request reprint What is the role of diet in the development of cancer in American Indian and Alaska native populations?
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84108, USA
    J Cancer Educ 20:92-6. 2005
    ..The associations between diet and cancer in American Indian and Alaska Native (AIAN) populations are not well understood...
  17. ncbi request reprint CYP1A1, cigarette smoking, and colon and rectal cancer
    Martha L Slattery
    Health Research Center, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
    Am J Epidemiol 160:842-52. 2004
    ..These data support the association between smoking and colon and rectal cancer. Smoking may have a greater impact on colorectal cancer risk based on CYP1A1 genotype; this might further be modified by GSTM1 for rectal cancer risk...
  18. ncbi request reprint Sex-specific differences in colon cancer associated with p53 mutations
    Martha L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City 84108, USA
    Nutr Cancer 49:41-8. 2004
    ..For these analyses, women were classified as estrogen positive or negative, based on menopausal status and use of hormone replacement therapy (HRT)...
  19. ncbi request reprint Associations among IRS1, IRS2, IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer
    Martha L Slattery
    Health Research Center, School of Medicine, University of Utah, Salt Lake City, 84108, USA
    Cancer Epidemiol Biomarkers Prev 13:1206-14. 2004
    ..We hypothesize that genetic polymorphisms of insulin receptor substrates (IRS-1 and IRS-2), IGF-I, and IGFBP-3 alter colorectal cancer risk because of their roles in the insulin-related signaling pathway...
  20. ncbi request reprint Dietary calcium, vitamin D, VDR genotypes and colorectal cancer
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84108, USA
    Int J Cancer 111:750-6. 2004
    ..The risk associated with VDR genotype seems to depend upon the level of dietary calcium and vitamin D and tumor site...
  21. ncbi request reprint Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway
    Martha L Slattery
    Health Research Center and Department of Pathology, School of Medicine, University of Utah, 375 Chipeta Way, Suite A, Salt Lake City, UT 84108, USA
    Cancer Epidemiol Biomarkers Prev 13:538-45. 2004
    ..We explore the associations between aspirin/NSAIDs, the insulin-related pathway, and the risk of colorectal cancer...
  22. ncbi request reprint Physical activity and colorectal cancer
    Martha L Slattery
    University of Utah, Health Research Center, Salt Lake City, Utah 84108, USA
    Sports Med 34:239-52. 2004
    ..It has been estimated that 12-14% of colon cancer could be attributed to lack of frequent involvement in vigorous physical activity...
  23. pmc IL6 genotypes and colon and rectal cancer
    Martha L Slattery
    School of Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Cancer Causes Control 18:1095-105. 2007
    ..This study provides further support for inflammation-related factors in the etiology of CRC. Other studies are needed to explore other genes in this and other inflammation-related pathways...
  24. ncbi request reprint Genetic, anthropometric, and lifestyle factors associated with IGF-1 and IGFBP-3 levels in Hispanic and non-Hispanic white women
    M L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84117, USA
    Cancer Causes Control 16:1147-57. 2005
    ..These differences could be due to the combined effects of genetic and behavioral factors which could account for ethnic differences in the risk of breast cancer and other chronic diseases...
  25. ncbi request reprint Physical activity patterns and obesity in Hispanic and non-Hispanic white women
    Martha L Slattery
    University of Utah, Salt Lake City, UT 84108, USA
    Med Sci Sports Exerc 38:33-41. 2006
    ..In this paper, we describe physical activity patterns of Hispanic and non-Hispanic white women living in the southwestern United States and the effects of these patterns on obesity...
  26. ncbi request reprint GSTM-1 and NAT2 and genetic alterations in colon tumors
    M L Slattery
    Health Research Center, Department of Family and Preventive Medicine, 375 Chipeta Way, Suite A, University of Utah, Salt Lake City, UT 84108, USA
    Cancer Causes Control 13:527-34. 2002
    ..In this study, we evaluate associations between the GSTM-1 genotype and the NAT2-imputed phenotype and acquired mutations in tumors...
  27. ncbi request reprint Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors
    M L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, USA
    J Natl Cancer Inst 92:1831-6. 2000
    ..It is unknown whether lifestyle factors associated with colon cancer, such as physical activity, body size, cigarette smoking, or use of aspirin and/or nonsteroidal anti-inflammatory drugs, contribute to MSI in sporadic tumors...
  28. ncbi request reprint Estrogens reduce and withdrawal of estrogens increase risk of microsatellite instability-positive colon cancer
    M L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City 84108, USA
    Cancer Res 61:126-30. 2001
    ..HRT in these older women may, again, reduce the risk of unstable tumors. A model for the way in which estrogens (endogenous, exogenous, and obesity-associated) modify the risk of MSI+ tumors is proposed...
  29. ncbi request reprint Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level
    W S Samowitz
    Departments of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Cancer Epidemiol Biomarkers Prev 10:917-23. 2001
    ..We conclude that microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level...
  30. ncbi request reprint The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer
    W S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Gastroenterology 121:830-8. 2001
    ..We therefore determined by genetic criteria the colon cancer burden associated with HNPCC in a population-based study of 1066 individuals from Utah and California...
  31. pmc Microsatellite instability and survival in rectal cancer
    Wade S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Cancer Causes Control 20:1763-8. 2009
    ..Very few studies have evaluated the effect of MSI-H on rectal cancer survival. We assessed MSI-H and other genetic and epigenetic changes on survival of 990 individuals diagnosed with first primary rectal cancer...
  32. ncbi request reprint Diet activity, and lifestyle associations with p53 mutations in colon tumors
    Martha L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, Utah 84108, USA
    Cancer Epidemiol Biomarkers Prev 11:541-8. 2002
    ..These data suggest that components of a Western-style diet such as high consumption of red meat and foods that increase glycemic load are associated with a p53 disease pathway...
  33. pmc Physical activity and breast cancer risk among women in the southwestern United States
    Martha L Slattery
    Department of Medicine, University of Utah, Salt Lake City, UT 84117, USA
    Ann Epidemiol 17:342-53. 2007
    ..01), while among postmenopausal HAI women, physical activity interacted with body mass index (p value, 0.04). These data suggest that physical activity is important in reducing risk of breast cancer in both NHW and HAI women...
  34. ncbi request reprint Diet composition and risk of overweight and obesity in women living in the southwestern United States
    Maureen A Murtaugh
    Division of Clinical Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA
    J Am Diet Assoc 107:1311-21. 2007
    ..We assessed the association of dietary patterns and macronutrient composition with overweight and obesity in Hispanic and non-Hispanic white women...
  35. ncbi request reprint Family history and colorectal cancer: predictors of risk
    M L Slattery
    Department of Family and Preventive Medicine, Health Research Center, University of Utah School of Medicine, 375 Chipeta Way, Suite A, Salt Lake City, UT 84108, USA
    Cancer Causes Control 14:879-87. 2003
    ..We also evaluate diet and lifestyle factors associated with developing colorectal cancer among participants with a positive family history...
  36. ncbi request reprint Polymorphisms in insulin-related genes predispose to specific KRAS2 and TP53 mutations in colon cancer
    Wade S Samowitz
    Department of Pathology, University of Utah, Salt Lake City, UT 84108, USA
    Mutat Res 595:117-24. 2006
    ....
  37. ncbi request reprint NAT2, GSTM-1, cigarette smoking, and risk of colon cancer
    M L Slattery
    University of Utah School of Medicine, Salt Lake City 84108, USA
    Cancer Epidemiol Biomarkers Prev 7:1079-84. 1998
    ..The lack of an association does not rule out the possibility of other genetic polymorphisms interacting with cigarette smoke to cause colon cancer, nor does it take into account individual phenotypic variability...
  38. ncbi request reprint Carotenoids and colon cancer
    M L Slattery
    University of Utah Medical School, Salt Lake City, USA
    Am J Clin Nutr 71:575-82. 2000
    ..However, except for beta-carotene, little is known about how dietary carotenoids are associated with common cancers, including colon cancer...
  39. ncbi request reprint Use of archival tissue in epidemiologic studies: collection procedures and assessment of potential sources of bias
    M L Slattery
    University of Utah, Department of Family and Preventive Medicine, School of Medicine, Salt Lake City 84117, USA
    Mutat Res 432:7-14. 2000
    ..However, we were less likely to be able to extract DNA if the case was diagnosed at a more advanced disease stage or at the earliest disease. Potential bias from exclusion of those with the most advanced disease stage is discussed...
  40. ncbi request reprint Dietary intake and microsatellite instability in colon tumors
    M L Slattery
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA
    Int J Cancer 93:601-7. 2001
    ..Most other dietary factors do not appear operate exclusively in the MSI+ disease pathway...
  41. ncbi request reprint Are dietary factors involved in DNA methylation associated with colon cancer?
    M L Slattery
    Department of Oncological Sciences, University of Utah, Salt Lake City 84108, USA
    Nutr Cancer 28:52-62. 1997
    ..4, 95% CI = 0.9-2.3; women OR = 2.0, 95% CI = 1.0-3.8). Findings from this study provide only limited support for previously reported associations between dietary factors involved in DNA methylation and risk of colon cancer...
  42. ncbi request reprint Energy balance and rectal cancer: an evaluation of energy intake, energy expenditure, and body mass index
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84108, USA
    Nutr Cancer 46:166-71. 2003
    ..However, both physical activity and energy intake were significantly associated with rectal cancer risk. These data suggest that energy expenditure and energy intake alter rectal cancer risk through mechanisms other than energy balance...
  43. ncbi request reprint Associations between smoking, passive smoking, GSTM-1, NAT2, and rectal cancer
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, Utah 84108, USA
    Cancer Epidemiol Biomarkers Prev 12:882-9. 2003
    ..This association may be influenced by GSTM-1 genotype. Furthermore, exposure to cigarette smoke of others may increase risk of rectal cancer among men who do not smoke...
  44. pmc The MLH1 -93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer
    Wade S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Genes Chromosomes Cancer 47:835-44. 2008
    ....
  45. pmc BAT-26 and BAT-40 instability in colorectal adenomas and carcinomas and germline polymorphisms
    W S Samowitz
    Department of Pathology, Oncological Sciences, University of Utah Health Sciences Center, Salt Lake City, Utah, USA
    Am J Pathol 154:1637-41. 1999
    ..Polymorphisms in these microsatellites, however, limit their utility in determinations of microsatellite instability without corresponding normal DNA...
  46. ncbi request reprint Risk of colon cancer associated with a family history of cancer or colorectal polyps: the diet, activity, and reproduction in colon cancer study
    R A Kerber
    Huntsman Cancer Institute and Department of Oncological Sciences, University of Utah, Salt Lake City, USA
    Int J Cancer 78:157-60. 1998
    ..A family history of colorectal polyps also increased risk by about the same amount as a family history of colorectal cancer. The increased risk associated with a family history of polyps did not appear to decrease with age...
  47. ncbi request reprint Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer
    Wade S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Gastroenterology 129:837-45. 2005
    ....
  48. ncbi request reprint Life After Cancer Epidemiology (LACE) Study: a cohort of early stage breast cancer survivors (United States)
    Bette Caan
    Division of Research, Kaiser Permanente Medical Care Program, 2000 Broadway, Oakland, CA 94612, USA
    Cancer Causes Control 16:545-56. 2005
    ..These data suggest that in the early years post-diagnosis, breast cancer survivors exhibit similar patterns to the general population in many health behaviors...
  49. ncbi request reprint A molecular variant of the APC gene at codon 1822: its association with diet, lifestyle, and risk of colon cancer
    M L Slattery
    Department of Family and Preventive Medicine University of Utah, Salt Lake City, 84112, USA
    Cancer Res 61:1000-4. 2001
    ..These results suggest that the codon 1,822 variant of the APC gene may have functional significance. Individuals who have the valine/valine variant of this gene may be at reduced risk of colon cancer if they eat a low-fat diet...
  50. ncbi request reprint Body mass index and colon cancer: an evaluation of the modifying effects of estrogen (United States)
    M L Slattery
    Health Research Center, Department of Family and Preventive Medicine, 375 Chipeta Way, Suite A, University of Utah, Salt Lake City, UT 84108, USA
    Cancer Causes Control 14:75-84. 2003
    ..The association between body mass index (BMI) and colon cancer has been reported to be different for men and women. No prior literature has examined if estrogen influences these differences...
  51. ncbi request reprint Vitamin E and colon cancer: is there an association?
    M L Slattery
    University of Utah Medical School, Salt Lake City 84108, USA
    Nutr Cancer 30:201-6. 1998
    ..80, 95% CI = 0.56-1.15). These data offer only limited support for a protective effect of vitamin E and colon cancer after adjustment for other health and life-style factors...
  52. pmc Pre-diagnosis body mass index, post-diagnosis weight change, and prognosis among women with early stage breast cancer
    Bette J Caan
    Division of Research, Kaiser Permanente Medical Program of Northern California, Oakland, CA 94612, USA
    Cancer Causes Control 19:1319-28. 2008
    ..We examined the association between body mass index (BMI) around the time of diagnosis, weight change post-diagnosis, and breast cancer prognosis in a prospective cohort study of 1,692 breast cancer survivors...
  53. pmc Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer
    W S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, 50 North Medical Dr, Salt Lake City, UT 84132, USA
    Am J Pathol 158:1517-24. 2001
    ....
  54. ncbi request reprint Uncommon TGFBRI allele is not associated with increased susceptibility to colon cancer
    W S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Genes Chromosomes Cancer 32:381-3. 2001
    ..We conclude that the 6A TGFBRI allele is not associated with an increased susceptibility to colon cancer at the population level, and that the 6A/6A homozygote is not restricted to individuals with some form of cancer...
  55. pmc A prospective cohort of American Indian and Alaska Native people: study design, methods, and implementation
    M L Slattery
    Department of Internal Medicine, The University of Utah, Salt Lake City, UT 84108, USA
    Am J Epidemiol 166:606-15. 2007
    ..The study has focused on involvement of American Indian and Alaska Native communities in development and implementation and on provision of feedback to participants and communities...
  56. ncbi request reprint Dietary fats and colon cancer: assessment of risk associated with specific fatty acids
    M L Slattery
    University of Utah Medical School, Salt Lake City, USA
    Int J Cancer 73:670-7. 1997
    ..Similar associations with family history were noted among men diagnosed at younger ages for MFA, linolenic acid and 20-carbon PFA...
  57. ncbi request reprint Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention
    Wade S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Clin Gastroenterol Hepatol 4:894-901. 2006
    ....
  58. pmc NSAIDs and breast cancer recurrence in a prospective cohort study
    Marilyn L Kwan
    Division of Research, Kaiser Permanente, 2000 Broadway, Oakland, CA 94612, USA
    Cancer Causes Control 18:613-20. 2007
    ..We examined the association between NSAID use and breast cancer recurrence in a prospective cohort of 2,292 early-stage breast cancer survivors diagnosed from 1997 to 2000 participating in the Life After Cancer Epidemiology (LACE) Study...
  59. ncbi request reprint Thymidylate synthase polymorphisms and colon cancer: associations with tumor stage, tumor characteristics and survival
    Karen Curtin
    Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    Int J Cancer 120:2226-32. 2007
    ..This study provides some support for associations between TS genotype and colon cancer tumor characteristics...
  60. pmc MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer
    Karen Curtin
    Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Mol Carcinog 48:989-94. 2009
    ..Age at diagnosis, family history, and alcohol use did not interact with MSH6 G39E and CIMP. The MSH6 G39E germline polymorphism may be associated with CIMP+ colon cancer...
  61. ncbi request reprint MTHFR C677T and A1298C polymorphisms: diet, estrogen, and risk of colon cancer
    Karen Curtin
    University of Utah Health Sciences Center, Salt Lake City, Utah, USA
    Cancer Epidemiol Biomarkers Prev 13:285-92. 2004
    ..The possible interaction with hormone-replacement therapy warrants additional investigation...
  62. ncbi request reprint Classification tree analysis: a statistical tool to investigate risk factor interactions with an example for colon cancer (United States)
    Nicola J Camp
    Genetic Epidemiology, Department of Medical Informatics, University of Utah, and Genetic Research, Intermountain Health Care, Salt Lake City 84108, USA
    Cancer Causes Control 13:813-23. 2002
    ..Classification tree analysis is a potentially powerful tool for investigating multilevel interactions. Within the context of colon cancer etiology it may help identify disease pathways and evaluate important interactions of risk factors...
  63. ncbi request reprint Eating frequency and the risk of colon cancer
    Ashley O Coates
    Division of Research, Kaiser Permanente Medical Care Program, Oakland, CA 94612 2304, USA
    Nutr Cancer 43:121-6. 2002
    ..The increased risk of colon cancer limited to men eating less than three times per day may be due to uncontrolled confounding...
  64. pmc Physical activity and risk of recurrence and mortality in breast cancer survivors: findings from the LACE study
    Barbara Sternfeld
    Division of Research, Kaiser Permanente, 2000 Broadway, Oakland, CA 94612, USA
    Cancer Epidemiol Biomarkers Prev 18:87-95. 2009
    ..The purpose of this study was to examine the association of physical activity following diagnosis and treatment with the risk of breast cancer recurrence and mortality and all-cause mortality in women with early-stage breast cancer...
  65. ncbi request reprint Low energy reporting may increase in intervention participants enrolled in dietary intervention trials
    Bette Caan
    Division of Research, Kaiser Permanente Medical Care Program of Northern California, 2000 Broadway, Oakland, CA 94612, USA
    J Am Diet Assoc 104:357-66; quiz 491. 2004
    ..To examine differences in low energy intake reporting between intervention and control groups during a dietary intervention trial...
  66. ncbi request reprint Does nutritionist review of a self-administered food frequency questionnaire improve data quality?
    B J Caan
    Kaiser Permanente Medical Care Program of Northern California, Division of Research, Oakland, CA 94611, USA
    Public Health Nutr 2:565-9. 1999
    ....
  67. pmc Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors
    Martha L Slattery
    University of Utah, Salt Lake City, Utah 84108, USA
    Nutr Cancer 62:436-42. 2010
    ..These data support an association between calcium and rectal tumors overall as well as specifically with TP53 mutations. However, given the number of comparisons, findings need to be confirmed in other studies...
  68. ncbi request reprint p53 alterations in colon tumors: a comparison of SSCP/sequencing and immunohistochemistry
    Karen Curtin
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Appl Immunohistochem Mol Morphol 12:380-6. 2004
    ..Advantages gained by sequencing are its ability to examine specific mutations and the improved ability to discriminate between cases with p 53 mutation and wild type when evaluating associations...
  69. ncbi request reprint Associations between BMI, energy intake, energy expenditure, VDR genotype and colon and rectal cancers (United States)
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, Utah 84108, USA
    Cancer Causes Control 15:863-72. 2004
    ..01 for colon and 0.04 for rectal). These data suggest a relationship between VDR genotype and factors related to energy balance in modifying colorectal cancer risk...
  70. ncbi request reprint Oral, injected and implanted contraceptives and breast cancer risk among U.S. Hispanic and non-Hispanic white women
    Carol Sweeney
    Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Int J Cancer 121:2517-23. 2007
    ..Based on a small number of users of contraceptive implants, a significantly increased breast cancer risk was observed; continued surveillance of implant users may be warranted...
  71. ncbi request reprint Development and use of touch-screen audio computer-assisted self-interviewing in a study of American Indians
    Sandra L Edwards
    Division of Clinical Epidemiology, Department of Internal Medicine, School of Medicine, University of Utah, Salt Lake City, UT 84132, USA
    Am J Epidemiol 165:1336-42. 2007
    ..These results indicate that the ACASI questionnaire is both an acceptable and a preferable mode of data collection in this population...
  72. pmc Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet
    Karen Curtin
    Department of Internal Medicine, University of Utah Health Sciences Center, 375 Chipeta Way, Suite A, Salt Lake City, UT 84108, USA
    Carcinogenesis 28:1672-9. 2007
    ..1, 95% CI = 1.3-3.4 versus AA/high risk; P-interaction = 0.03). These results provide only limited support for a role of polymorphisms in one-carbon metabolism in the etiology of CIMP colon cancer...
  73. pmc Development, implementation, and evaluation of a computerized self-administered diet history questionnaire for use in studies of American Indian and Alaskan native people
    Martha L Slattery
    University of Utah, Internal Medicine, Salt Lake City, UT 84108, USA
    J Am Diet Assoc 108:101-9. 2008
    ..The methods developed for collection of dietary data appear to be appropriate for the targeted population and may have usefulness for other populations where collecting dietary data in a self-administered format is desirable...
  74. pmc Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors
    Carol Sweeney
    Health Sciences Center, University of Utah, Salt Lake City, UT, USA
    Genes Chromosomes Cancer 48:1-9. 2009
    ..The oncogenetic tree model assumptions are appropriate for the observed heterogeneity of colon tumors, and the model produces a useful visual schematic of the sequence of events in pathways of colon carcinogenesis...
  75. pmc Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival
    Martha L Slattery
    Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84108, USA
    Int J Cancer 128:2726-34. 2011
    ..These data suggest that genetic variation in the CRP gene influences risk of both colon and rectal cancer development...
  76. ncbi request reprint The CYP1A1 genotype may alter the association of meat consumption patterns and preparation with the risk of colorectal cancer in men and women
    Maureen A Murtaugh
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT 84101, USA
    J Nutr 135:179-86. 2005
    ..Genetic susceptibility may modify the associations of some meat or meat preparation factors with the risk of colorectal cancer...
  77. pmc A comparison of colon and rectal somatic DNA alterations
    Martha L Slattery
    Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84108, USA
    Dis Colon Rectum 52:1304-11. 2009
    ..Differences in acquired mutations in colon and rectal tumors may account for differences in risk factors. In this study, we examined similarities and differences in somatic alterations in colon and rectal tumors...
  78. ncbi request reprint Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers
    Wade S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City 84132, USA
    Cancer Res 65:6063-9. 2005
    ....
  79. doi request reprint Analysis of dietary patterns in epidemiological research
    Martha L Slattery
    Department of Medicine, University of Utah, 375 Chipeta Way, Salt Lake City, UT 84108, USA
    Appl Physiol Nutr Metab 35:207-10. 2010
    ..Additionally, the utilization of dietary patterns as a tool for public health messages is a topic that is unresolved. These issues are discussed in this paper...
  80. pmc Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes
    Martha L Slattery
    Department of Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Cancer Causes Control 21:1237-45. 2010
    ..68 95% CI 0.47, 0.98; p linear trend 0.03). These data suggest that diet and lifestyle factors are associated with specific types of rectal tumor mutations and epigenetic changes. Findings need confirmation in other studies...
  81. pmc Increased risk of colon cancer associated with a genetic polymorphism of SMAD7
    Martha L Slattery
    Departments of Internal Medicine and Pathology, University of Utah School of Medicine, 375 Chipeta Way, Suite A, Salt Lake City, UT 84108, USA
    Cancer Res 70:1479-85. 2010
    ..No significant associations were observed for the rs4464148 SNP or other SNPs evaluated in the SMAD7. These results corroborate the findings of GWAS in colon cancer pointing to SMAD7 and reinforce interest in SNPs in this gene...
  82. pmc Validation of a dietary history questionnaire for American Indian and Alaska Native people
    Maureen A Murtaugh
    Division of Epidemiology, Department of Internal Medicine, University of Utah, 295 Chipeta Way, Salt Lake City, Utah 84132, USA
    Ethn Dis 20:429-36. 2010
    ....
  83. ncbi request reprint Genetic admixture among Hispanics and candidate gene polymorphisms: potential for confounding in a breast cancer study?
    Carol Sweeney
    Department of Internal Medicine Health Research Center, University of Utah, Salt Lake City, Utah, USA
    Cancer Epidemiol Biomarkers Prev 16:142-50. 2007
    ..CRRs from simulated scenarios indicated that appreciable confounding by admixture would occur only when within-group candidate SNP allele frequency differences are much larger than any that we observed...
  84. ncbi request reprint Associations between vitamin D, vitamin D receptor gene and the androgen receptor gene with colon and rectal cancer
    Martha L Slattery
    University of Utah, Health Research Center, Salt Lake City, USA
    Int J Cancer 118:3140-6. 2006
    ..05) relative to men with fewer than 23 CAG repeats of the AR gene. These data provide support for the role of vitamin D and sunshine exposure in the etiology of colorectal cancer and suggest that AR gene may modulate the association...
  85. ncbi request reprint Associations between ERalpha, ERbeta, and AR genotypes and colon and rectal cancer
    Martha L Slattery
    Health Research Center, School of Medicine, University of Utah, 375 Chipeta Way, Suite A, Salt Lake City, UT 84108, USA
    Cancer Epidemiol Biomarkers Prev 14:2936-42. 2005
    ..71; 95% CI, 2.89-15.6). Our results suggest that the ERbeta gene is more important than ERalpha in the etiology of colorectal cancer...
  86. ncbi request reprint Post-diagnosis weight gain and breast cancer recurrence in women with early stage breast cancer
    Bette J Caan
    Division of Research, Kaiser Permanente Medical Group, 2000 Broadway, 94612 Oakland, CA, USA
    Breast Cancer Res Treat 99:47-57. 2006
    ..To examine whether weight gain after diagnosis of breast cancer affects the risk of breast cancer recurrence...
  87. ncbi request reprint APC mutations and other genetic and epigenetic changes in colon cancer
    Wade S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Mol Cancer Res 5:165-70. 2007
    ..The relationships of APC mutations to other genetic and epigenetic alterations add to the already impressive genetic heterogeneity of colon cancer...
  88. ncbi request reprint Prognostic significance of p53 mutations in colon cancer at the population level
    Wade S Samowitz
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Int J Cancer 99:597-602. 2002
    ..However, specific classes of mutations, namely, the G245 hot spot mutation and mutations in proximal tumors, are related to significantly worse survival even after adjusting for age and stage...
  89. ncbi request reprint Antioxidants, carotenoids, and risk of rectal cancer
    Maureen A Murtaugh
    Health Research Center, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Am J Epidemiol 159:32-41. 2004
    ..Associations differed by estrogen status for beta-carotene, lycopene, and vitamin E. These results suggest that vitamin E and lycopene may modestly reduce the risk of rectal cancer in women...
  90. pmc Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways
    Martha L Slattery
    Department of Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Mutat Res 660:12-21. 2009
    ..The important modifying effects of aspirin/NSAIDs on associations with genetic polymorphisms reinforce the underlying role of inflammation in the etiology of colon cancer...
  91. ncbi request reprint IL6, aspirin, nonsteroidal anti-inflammatory drugs, and breast cancer risk in women living in the southwestern United States
    Martha L Slattery
    Health Research Center, University of Utah, Salt Lake City, UT 84117, USA
    Cancer Epidemiol Biomarkers Prev 16:747-55. 2007
    ..04 (for Hispanic/Native American) and SNP rs1800796 or -572G>C]. These data suggest that IL6 is associated with breast cancer risk and modifies the association between estrogen and aspirin and breast cancer risk...
  92. ncbi request reprint Intake of fluids and methylxanthine-containing beverages: association with colon cancer
    M L Slattery
    University of Utah School of Medicine, Salt Lake City 84108, USA
    Int J Cancer 81:199-204. 1999
    ..68, 95% CI 0.49-0.96). Assessment of the impact of smoking on associations between colon cancer and coffee showed a significant interaction between smoking and coffee for both men and women...
  93. ncbi request reprint Contacting controls: are we working harder for similar response rates, and does it make a difference?
    A Rogers
    Health Research Center, Department of Family and Preventive Medicine, School of Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Am J Epidemiol 160:85-90. 2004
    ..The amount of effort required to achieve similar or slightly lower response rates increased over time. This finding may in part depend on demographic characteristics of the population studied...
  94. ncbi request reprint Environmental determinants of urinary kallikrein excretion
    S C Hunt
    Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City
    Am J Hypertens 6:226-33. 1993
    ....
  95. ncbi request reprint Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer
    Cornelia M Ulrich
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 B402 Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 14:2509-16. 2005
    ..A pathway-based approach to data analysis is needed to help discern the independent and combined effects of dietary intakes and genetic variability in folate metabolism...
  96. ncbi request reprint Prostate cancer risk and IRS1, IRS2, IGF1, and INS polymorphisms: strong association of IRS1 G972R variant and cancer risk
    Susan L Neuhausen
    Department of Medicine, Division of Epidemiology, University of California Irvine, Irvine, CA 92697 7550, USA
    Prostate 64:168-74. 2005
    ..We hypothesized that functional polymorphisms in INS, IRS1, IRS2, and IGF1 may be associated with prostate cancer...
  97. ncbi request reprint The association of calcium and vitamin D with risk of colorectal adenomas
    Terryl J Hartman
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA
    J Nutr 135:252-9. 2005
    ..14) on risk for adenoma recurrence. This trial cohort provides some evidence that calcium and vitamin D may be inversely associated with adenoma recurrence...
  98. ncbi request reprint Adenomatous polyp recurrence and physical activity in the Polyp Prevention Trial (United States)
    Lisa H Colbert
    National Institute on Aging, Bethesda, MD, USA
    Cancer Causes Control 13:445-53. 2002
    ..To examine prospectively the association between physical activity and adenomatous polyp recurrence...
  99. ncbi request reprint Fast-food habits, weight gain, and insulin resistance (the CARDIA study): 15-year prospective analysis
    Mark A Pereira
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Lancet 365:36-42. 2005
    ..We aimed to investigate the association between reported fast-food habits and changes in bodyweight and insulin resistance over a 15-year period in the USA...
  100. ncbi request reprint Microsomal epoxide hydrolase polymorphisms are not associated with colon cancer risk
    Kim Robien
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, P O Box 19024, M4 B402, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 14:1350-2. 2005