Ahna R Skop

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Profiling of the mammalian mitotic spindle proteome reveals an ER protein, OSTD-1, as being necessary for cell division and ER morphology
    Mary Kate Bonner
    Laboratory of Genetics and Medical Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 8:e77051. 2013
  2. pmc Mitotic spindle proteomics in Chinese hamster ovary cells
    Mary Kate Bonner
    Department of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 6:e20489. 2011
  3. pmc Long astral microtubules and RACK-1 stabilize polarity domains during maintenance phase in Caenorhabditis elegans embryos
    Erkang Ai
    Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 6:e19020. 2011
  4. pmc Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms
    Ahna R Skop
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA
    Science 305:61-6. 2004
  5. pmc Arp2/3 mediates early endosome dynamics necessary for the maintenance of PAR asymmetry in Caenorhabditis elegans
    Jessica M Shivas
    Department of Genetics and Medical Genetics, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Biol Cell 23:1917-27. 2012
  6. pmc RACK-1 directs dynactin-dependent RAB-11 endosomal recycling during mitosis in Caenorhabditis elegans
    Erkang Ai
    Laboratory of Genetics, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Biol Cell 20:1629-38. 2009
  7. pmc Dynamin participates in the maintenance of anterior polarity in the Caenorhabditis elegans embryo
    Yuji Nakayama
    Department of Genetics, University of Wisconsin Madison, Madison, WI 53706, USA
    Dev Cell 16:889-900. 2009
  8. pmc Anterior PAR proteins function during cytokinesis and maintain DYN-1 at the cleavage furrow in Caenorhabditis elegans
    Kelly J Pittman
    Laboratory of Genetics and Medical Genetics, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Cytoskeleton (Hoboken) 69:826-39. 2012
  9. doi request reprint Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos
    Haining Zhang
    Laboratory of Genetics, University of Wisconsin, Madison, WI 53706, USA
    J Cell Sci 121:155-61. 2008
  10. pmc Cell division screens and dynamin
    Mary Kate Bonner
    Department of Genetics, University of Wisconsin Madison, 425 G Henry Mall, Madison, WI 53706, USA
    Biochem Soc Trans 36:431-5. 2008

Collaborators

Detail Information

Publications16

  1. pmc Profiling of the mammalian mitotic spindle proteome reveals an ER protein, OSTD-1, as being necessary for cell division and ER morphology
    Mary Kate Bonner
    Laboratory of Genetics and Medical Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 8:e77051. 2013
    ..In addition, 65% of all ostd-1 RNAi-treated embryos failed to correctly position cleavage furrows, suggesting that proper ER morphology plays a necessary function during animal cell division. ..
  2. pmc Mitotic spindle proteomics in Chinese hamster ovary cells
    Mary Kate Bonner
    Department of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 6:e20489. 2011
    ..Our data represent the first mitotic spindle proteome in CHO cells, which augments the list of mitotic spindle components from mammalian cells...
  3. pmc Long astral microtubules and RACK-1 stabilize polarity domains during maintenance phase in Caenorhabditis elegans embryos
    Erkang Ai
    Laboratory of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 6:e19020. 2011
    ..We found a correlation between short astral microtubules and the instability of PAR-6 and PAR-2 domains during maintenance phase. Our data support a necessary role for astral microtubules in the maintenance phase of cell polarity...
  4. pmc Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms
    Ahna R Skop
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA
    Science 305:61-6. 2004
    ....
  5. pmc Arp2/3 mediates early endosome dynamics necessary for the maintenance of PAR asymmetry in Caenorhabditis elegans
    Jessica M Shivas
    Department of Genetics and Medical Genetics, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Biol Cell 23:1917-27. 2012
    ..We propose a model in which Arp2/3 affects the efficiency of rapid endocytic recycling of polarity cues that ultimately contributes to their stable maintenance...
  6. pmc RACK-1 directs dynactin-dependent RAB-11 endosomal recycling during mitosis in Caenorhabditis elegans
    Erkang Ai
    Laboratory of Genetics, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Biol Cell 20:1629-38. 2009
    ..Our findings suggest a mechanism by which RACK-1 directs the dynactin-dependent redistribution of recycling endosomes during the cell cycle, thus ensuring proper membrane trafficking events during cytokinesis...
  7. pmc Dynamin participates in the maintenance of anterior polarity in the Caenorhabditis elegans embryo
    Yuji Nakayama
    Department of Genetics, University of Wisconsin Madison, Madison, WI 53706, USA
    Dev Cell 16:889-900. 2009
    ..Our results demonstrate a mechanism for the spatial and temporal regulation of endocytosis in the anterior of the embryo, contributing to the precise localization and maintenance of polarity factors within a dynamic plasma membrane...
  8. pmc Anterior PAR proteins function during cytokinesis and maintain DYN-1 at the cleavage furrow in Caenorhabditis elegans
    Kelly J Pittman
    Laboratory of Genetics and Medical Genetics, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Cytoskeleton (Hoboken) 69:826-39. 2012
    ..Our data indicate that the PAR proteins are involved in the events that occur during cytokinesis and may play a role in promoting the membrane trafficking and remodeling events that occur during this time...
  9. doi request reprint Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos
    Haining Zhang
    Laboratory of Genetics, University of Wisconsin, Madison, WI 53706, USA
    J Cell Sci 121:155-61. 2008
    ..By RNAi of a weak dnc-1(ts) allele, we showed that dynactin activity was required at least for EMS spindle rotational alignment...
  10. pmc Cell division screens and dynamin
    Mary Kate Bonner
    Department of Genetics, University of Wisconsin Madison, 425 G Henry Mall, Madison, WI 53706, USA
    Biochem Soc Trans 36:431-5. 2008
    ..Our review will describe current knowledge regarding the impacts of several cell division screens and the multiple roles that dynamin may play during mitosis...
  11. pmc Polarity and endocytosis: reciprocal regulation
    Jessica M Shivas
    Laboratory of Genetics, University of Wisconsin, Madison, WI 53706, USA
    Trends Cell Biol 20:445-52. 2010
    ..Here, we review emerging evidence for the reciprocal regulation between polarity proteins and endocytic pathways, and discuss possible models for how these distinct processes could interact to create separate cellular domains...
  12. pmc SPD-3 is required for spindle alignment in Caenorhabditis elegans embryos and localizes to mitochondria
    Maria V Dinkelmann
    Laboratory of Genetics, University of Wisconsin, Madison, Wisconsin 53706, USA
    Genetics 177:1609-20. 2007
    ..elegans. To our knowledge, SPD-3 is the first example of a link between mitochondria and spindle alignment in C. elegans...
  13. pmc Dynamin and cytokinesis
    Catherine A Konopka
    Department of Biochemistry and Program in Cellular and Molecular Biology, University of Wisconsin Madison, Madison, WI 53706, USA
    Traffic 7:239-47. 2006
    ..In this review, we highlight the conserved contribution of classical dynamin and dynamin-related proteins during cytokinesis in both animal and plant systems...
  14. ncbi request reprint Spindlegate: the biological consequences of disrupting traffic
    Megan M Gnazzo
    Laboratory of Genetics and Medical Genetics, University of Wisconsin Madison, Madison, WI 53706, USA
    Dev Cell 28:480-2. 2014
    ..The function of membrane trafficking during mitosis has become the focus of increasing interest. In this issue of Developmental Cell, Hehnly and Doxsey (2014) provide new insight into the role that endosomes play during spindle assembly. ..
  15. pmc Midbodies and phragmoplasts: analogous structures involved in cytokinesis
    Marisa S Otegui
    Department of Botany, University of Wisconsin Madison, 430 Lincoln Drive, Madison, WI 53706, USA
    Trends Cell Biol 15:404-13. 2005
    ....
  16. pmc The large GTPase dynamin associates with the spindle midzone and is required for cytokinesis
    Heather M Thompson
    GI Basic Research and Department of Biochemistry and Molecular Biology, Mayo Clinic and Mayo Graduate School, Rochester, Minnesota 55905, USA
    Curr Biol 12:2111-7. 2002
    ..These findings indicate that, during mitosis, conventional dynamin is recruited to the spindle midzone and the subsequent intercellular bridge, where it plays an essential role in the final separation of dividing cells...