Janet S Sinsheimer

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Using the maternal-fetal genotype incompatibility test to assess non-inherited maternal HLA-DRB1 antigen coding alleles as rheumatoid arthritis risk factors
    Hsin Ju Hsieh
    Genentech, Inc, 1 DNA Way, South San Francisco, California 94080, USA
    BMC Proc 1:S124. 2007
  2. ncbi request reprint SNPs and snails and puppy dogs' tails: analysis of SNP haplotype data using the gamete competition model
    J S Sinsheimer
    Department of Human Genetics and Biomathematics, The University of California, Los Angeles 90095 1766, USA
    Ann Hum Genet 65:483-90. 2001
  3. pmc Estimating ethnic admixture from pedigree data
    Janet S Sinsheimer
    Department of Human Genetics, The University of California, Los Angeles, CA 90095, USA
    Am J Hum Genet 82:748-55. 2008
  4. ncbi request reprint Are you my mother? Bayesian phylogenetic inference of recombination among putative parental strains
    Janet S Sinsheimer
    Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095 1766, USA
    Appl Bioinformatics 2:131-44. 2003
  5. ncbi request reprint Detecting genotype combinations that increase risk for disease: maternal-fetal genotype incompatibility test
    Janet S Sinsheimer
    Department of Human Genetics, University of California, Los Angeles, California 90095 1766, USA
    Genet Epidemiol 24:1-13. 2003
  6. pmc Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans
    Daphna Weissglas-Volkov
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, Calif 90095 7088, USA
    Arterioscler Thromb Vasc Biol 30:353-9. 2010
  7. pmc Effect of Rhesus D incompatibility on schizophrenia depends on offspring sex
    Christina G S Palmer
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, 90095, USA
    Schizophr Res 104:135-45. 2008
  8. pmc Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples
    Daphna Weissglas-Volkov
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 7088, USA
    Circ Cardiovasc Genet 3:31-8. 2010
  9. pmc Modeling maternal-offspring gene-gene interactions: the extended-MFG test
    Erica J Childs
    Department of Biostatistics, University of California, Los Angeles, California, USA
    Genet Epidemiol 34:512-21. 2010
  10. ncbi request reprint RHD maternal-fetal genotype incompatibility and schizophrenia: extending the MFG test to include multiple siblings and birth order
    Peter Kraft
    Department of Epidemiology and Biostatistics, Harvard School of Public Health, University of California, Los Angeles, USA
    Eur J Hum Genet 12:192-8. 2004

Research Grants

Detail Information

Publications56

  1. pmc Using the maternal-fetal genotype incompatibility test to assess non-inherited maternal HLA-DRB1 antigen coding alleles as rheumatoid arthritis risk factors
    Hsin Ju Hsieh
    Genentech, Inc, 1 DNA Way, South San Francisco, California 94080, USA
    BMC Proc 1:S124. 2007
    ..We discuss possible reasons why our result conflicts with several previous studies (including one of our own) that used RA patients from northern Europe...
  2. ncbi request reprint SNPs and snails and puppy dogs' tails: analysis of SNP haplotype data using the gamete competition model
    J S Sinsheimer
    Department of Human Genetics and Biomathematics, The University of California, Los Angeles 90095 1766, USA
    Ann Hum Genet 65:483-90. 2001
    ..Because pedigree implementations of the gamete competition model can accommodate dominant as well as codominant markers, they circumvent the phase problem by including all possible phases weighted by their estimated frequencies...
  3. pmc Estimating ethnic admixture from pedigree data
    Janet S Sinsheimer
    Department of Human Genetics, The University of California, Los Angeles, CA 90095, USA
    Am J Hum Genet 82:748-55. 2008
    ..The utility of the method is demonstrated on simulated data and a real data example involving Mexican families of mixed Amerindian and Spanish ancestry...
  4. ncbi request reprint Are you my mother? Bayesian phylogenetic inference of recombination among putative parental strains
    Janet S Sinsheimer
    Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095 1766, USA
    Appl Bioinformatics 2:131-44. 2003
    ....
  5. ncbi request reprint Detecting genotype combinations that increase risk for disease: maternal-fetal genotype incompatibility test
    Janet S Sinsheimer
    Department of Human Genetics, University of California, Los Angeles, California 90095 1766, USA
    Genet Epidemiol 24:1-13. 2003
    ....
  6. pmc Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans
    Daphna Weissglas-Volkov
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, Calif 90095 7088, USA
    Arterioscler Thromb Vasc Biol 30:353-9. 2010
    ..This study attempted to determine these genetic factors...
  7. pmc Effect of Rhesus D incompatibility on schizophrenia depends on offspring sex
    Christina G S Palmer
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, 90095, USA
    Schizophr Res 104:135-45. 2008
    ..Sex differences during fetal neurodevelopment should be investigated to fully elucidate the etiology of schizophrenia...
  8. pmc Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples
    Daphna Weissglas-Volkov
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 7088, USA
    Circ Cardiovasc Genet 3:31-8. 2010
    ....
  9. pmc Modeling maternal-offspring gene-gene interactions: the extended-MFG test
    Erica J Childs
    Department of Biostatistics, University of California, Los Angeles, California, USA
    Genet Epidemiol 34:512-21. 2010
    ....
  10. ncbi request reprint RHD maternal-fetal genotype incompatibility and schizophrenia: extending the MFG test to include multiple siblings and birth order
    Peter Kraft
    Department of Epidemiology and Biostatistics, Harvard School of Public Health, University of California, Los Angeles, USA
    Eur J Hum Genet 12:192-8. 2004
    ..7, consistent with earlier estimates. Our extension of the MFG test has general application to family-based studies of maternal-genotype and MFG interaction effects...
  11. ncbi request reprint Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia
    Rebecca Mar
    Department of Human Genetics, University of California, Los Angeles, USA
    Circ Res 94:993-9. 2004
    ....
  12. pmc Galanin preproprotein is associated with elevated plasma triglycerides
    Christopher L Plaisier
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Gonda Center, 695 Charles E Young Drive South, Los Angeles, CA 90095 7088, USA
    Arterioscler Thromb Vasc Biol 29:147-52. 2009
    ..We hypothesized that variation in the galanin preproprotein (GAL) gene may contribute to hypertriglyceridemia (HTG) in humans...
  13. ncbi request reprint Allowing for missing data at highly polymorphic genes when testing for maternal, offspring and maternal-fetal genotype incompatibility effects
    Hsin Ju Hsieh
    Biostatistics, University of California, Los Angeles, CA, USA
    Hum Hered 62:165-74. 2006
    ..The MFG test using the IBS framework is immune to population stratification and efficiently uses information from incomplete families...
  14. pmc A heterozygote-homozygote test of Hardy-Weinberg equilibrium
    Jin J Zhou
    Department of Biomathematics, The University of California, Los Angeles, 90095, USA
    Eur J Hum Genet 17:1495-500. 2009
    ..No prior haplotyping is necessary. Our experience on real and simulated data suggests that the heterozygous-homozygous test has good type-one error and power...
  15. pmc Detection of intergenerational genetic effects with application to HLA-B matching as a risk factor for schizophrenia
    Erica J Childs
    Department of Biostatistics, University of California, Los Angeles, CA 90095, USA
    Hum Hered 72:161-72. 2011
    ..We apply our methods to schizophrenia pedigrees to investigate whether the previously associated mother-daughter HLA-B matching is a genuine risk or the result of bias...
  16. ncbi request reprint Models for estimating bayes factors with applications to phylogeny and tests of monophyly
    Marc A Suchard
    Department of Biomathematics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Biometrics 61:665-73. 2005
    ..The second example focuses on HIV recombination detection. For potential clinical application, these types of analyses must be completed as efficiently as possible...
  17. ncbi request reprint USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease
    Jenny C Lee
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Arterioscler Thromb Vasc Biol 27:2222-7. 2007
    ..Here we examined the previously associated rs3737787 SNP in extended Dutch FCHL families (n=532) and in a cohort of US subjects who underwent diagnostic coronary angiography (n=1533)...
  18. ncbi request reprint Oh brother, where art thou? A Bayes factor test for recombination with uncertain heritage
    Marc A Suchard
    Department of Biomathematics, School of Medicine, University of California, Los Angeles, California 90095 1766, USA
    Syst Biol 51:715-28. 2002
    ..We employed scaled regeneration quantile plots to assess convergence and found this approach convenient to use even for our variable dimensional model parameter space...
  19. pmc Expression quantitative trait loci: replication, tissue- and sex-specificity in mice
    Atila Van Nas
    Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
    Genetics 185:1059-68. 2010
    ..We conclude that most local eQTL are highly replicable between mouse crosses, tissues, and sex as compared to distal eQTL, which exhibited modest replicability...
  20. pmc Prioritizing GWAS results: A review of statistical methods and recommendations for their application
    Rita M Cantor
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Am J Hum Genet 86:6-22. 2010
    ..Reviews of published methods with recommendations for their application are provided within the framework for each approach...
  21. ncbi request reprint The v-MFG test: investigating maternal, offspring and maternal-fetal genetic incompatibility effects on disease and viability
    Hsin Ju Hsieh
    Biostatistics, University of California, Los Angeles, CA, USA
    Genet Epidemiol 30:333-47. 2006
    ....
  22. pmc HLA-B maternal-fetal genotype matching increases risk of schizophrenia
    Christina G S Palmer
    Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA 90095, USA
    Am J Hum Genet 79:710-5. 2006
    ..Our approach demonstrates how genetic markers can be used to characterize the biology of prenatal risk factors of schizophrenia...
  23. pmc The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans
    Daphna Weissglas-Volkov
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 7088, USA
    J Clin Invest 121:3062-71. 2011
    ..Our findings suggest that modulation of MYLIP activity can affect LDL-C levels and that pharmacologic inhibition of MYLIP activity might be a useful strategy in the treatment of dyslipidemia and ASCVD...
  24. pmc RHD maternal-fetal genotype incompatibility increases schizophrenia susceptibility
    Christina G S Palmer
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, 90095, USA
    Am J Hum Genet 71:1312-9. 2002
    ..This is the first candidate-gene study to explicitly test for and provide evidence of a maternal-fetal genotype incompatibility mechanism in schizophrenia...
  25. ncbi request reprint An exact maternal-fetal genotype incompatibility (MFG) test
    Sonia L Minassian
    Department of Biostatistics, University of California, Los Angeles, California 90095 1766, USA
    Genet Epidemiol 28:83-95. 2005
    ..Under these conditions, the exact test is clearly preferred over the asymptotic test. Under all other conditions that we tested, the user can safely choose either the exact test or the asymptotic test...
  26. pmc Extinction models for cancer stem cell therapy
    Mary Sehl
    Department of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Math Biosci 234:132-46. 2011
    ..The current cancer models demonstrate the virtue of attacking the same quantitative questions from a variety of modeling, mathematical, and computational perspectives...
  27. pmc Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women
    Carolyn J Crandall
    Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, UCLA Medicine GIM, 911 Broxton Ave, 1st Floor, Los Angeles, CA 90024, USA
    Breast Cancer Res 11:R51. 2009
    ....
  28. ncbi request reprint Hierarchical phylogenetic models for analyzing multipartite sequence data
    Marc A Suchard
    Department of Biomathematics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095 1766, USA
    Syst Biol 52:649-64. 2003
    ..Preliminary results suggest evolution and not reemergence...
  29. ncbi request reprint Association testing with Mendel
    Kenneth Lange
    Department of Biomathematics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 7088, USA
    Genet Epidemiol 29:36-50. 2005
    ..This report explains how Mendel imputes allele counts and conducts both asymptotic and permutation tests in the measured genotype framework...
  30. ncbi request reprint Testing a molecular clock without an outgroup: derivations of induced priors on branch-length restrictions in a Bayesian framework
    Marc A Suchard
    Department of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, California 90095 1766, USA
    Syst Biol 52:48-54. 2003
    ..These derivations also have more general applicability to the examination of prior assumptions in Bayesian phylogenetics...
  31. doi request reprint Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci
    Daphna Weissglas-Volkov
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Gonda Center, Room 6335B, 695 Charles E Young Drive South, Los Angeles, CA 90095 7088, USA
    J Med Genet 50:298-308. 2013
    ..Yet, these populations remain underinvestigated by genomic studies, and to date, no genome-wide association (GWA) studies have been reported for lipids in these rapidly expanding populations...
  32. pmc Exome sequencing identifies 2 rare variants for low high-density lipoprotein cholesterol in an extended family
    M V Prasad Linga Reddy
    Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Circ Cardiovasc Genet 5:538-46. 2012
    ..Less is known about its feasibility to identify genes for complex traits. We used exome sequencing to search for rare variants responsible for a complex trait, low levels of serum high-density lipoprotein cholesterol (HDL-C)...
  33. pmc Does history repeat itself? Wavelets and the phylodynamics of influenza A
    Jennifer A Tom
    Department of Biostatistics, School of Public Health, University of California, Los Angeles, CA, USA
    Mol Biol Evol 29:1367-77. 2012
    ..We also address hypotheses regarding intersegment dynamics within a formal statistical framework that accounts for correlation between segment-specific parameters...
  34. ncbi request reprint Applications of codon and rate variation models in molecular phylogeny
    Eric E Schadt
    Department of Biomathematics, UCLA School of Medicine, Los Angeles, USA
    Mol Biol Evol 19:1550-62. 2002
    ..All the new statistical algorithms applied are incorporated in our phylogeny software LINNAEUS, which is tuned for performance and modeling flexibility...
  35. doi request reprint Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women
    Robin L Seitzman
    Department of Ophthalmology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 92122, USA
    Am J Epidemiol 167:1217-25. 2008
    ..02). The MMP2 rs2287074 A allele may be associated with a lower likelihood of ARM in older Caucasian women, particularly those who have never used hormone therapy. The role of MMP2 rs2287074 in ARM should be further elucidated...
  36. pmc Mendel: the Swiss army knife of genetic analysis programs
    Kenneth Lange
    Department of Human Genetics and Department of Biomathematics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA, Department of Statistics, Department of Biostatistics, Fielding School of Public Health, UCLA, Los Angeles, CA 90095, USA and Department of Statistics, North Carolina State University, Raleigh, NC 27695, USA
    Bioinformatics 29:1568-70. 2013
    ..Compared with earlier versions, Mendel is faster and easier to use and has a wider range of applications. Supported platforms include Linux, MacOS and Windows. Availability: Free from www.genetics.ucla.edu/software/mendel..
  37. pmc Differential destruction of stem cells: implications for targeted cancer stem cell therapy
    Mary E Sehl
    Division of Hematology Oncology, Department of Medicine, University of California, Los Angeles, California 90095 7059, USA
    Cancer Res 69:9481-9. 2009
    ..We anticipate that in conjunction with experimental observation of cancer stem cell killing rates, our results will be useful in screening targeted therapies for both hematologic and solid tumor malignancies...
  38. ncbi request reprint The pedigree trimming problem
    Kenneth Lange
    Department of Biomathematics, University of California, Los Angeles, CA 90095 1766, USA
    Hum Hered 58:108-11. 2004
    ..Of course, each pedigree of interest will have some core people who must be retained. The described algorithm retains just enough of the pedigree to maintain the proper relationships among the core people...
  39. pmc Association screening of common and rare genetic variants by penalized regression
    Hua Zhou
    Department of Statistics, North Carolina State University, Raleigh, NC 27695 8203, USA
    Bioinformatics 26:2375-82. 2010
    ..This article extends our recent research on penalized estimation methods in genome-wide association studies to the realm of rare variants...
  40. pmc Associations between single nucleotide polymorphisms in double-stranded DNA repair pathway genes and familial breast cancer
    Mary E Sehl
    Divisions of Hematology and Oncology and Geriatrics, Department of Medicine, David Geffen School of Medicine at University of California at Los Angeles, USA
    Clin Cancer Res 15:2192-203. 2009
    ..DNA damage recognition and repair play a major role in risk for breast cancer. We investigated 104 single nucleotide polymorphisms (SNP) in 17 genes whose protein products are involved in double-stranded break repair (DSBR)...
  41. pmc Graph hierarchies for phylogeography
    Gabriela B Cybis
    Department of Biomathematics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    Philos Trans R Soc Lond B Biol Sci 368:20120206. 2013
    ..We first examine the evolutionary history of multiple serotypes of dengue virus in the Americas to showcase our method. Additionally, we explore an application to intrahost HIV evolution across multiple patients...
  42. doi request reprint Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults
    Andrew J Levine
    National Neurological AIDS Bank, Department of Neurology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 34:78-91. 2012
    ..We report analyses examining the main effects of functional polymorphisms within dopamine-modulating genes, as well as their interactive effects with disease severity, upon neurocognitive functioning in HIV+ adults...
  43. pmc Epigenetic predictor of age
    Sven Bocklandt
    Department of Human Genetics, University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 6:e14821. 2011
    ....
  44. pmc Replication of GWAS associations for GAK and MAPT in Parkinson's disease
    Shannon L Rhodes
    Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095 1772, USA
    Ann Hum Genet 75:195-200. 2011
    ..14) did not replicate in our study population. While MAPT has been considered a PD candidate gene and has been observed in association with PD in other GWAS, GAK is a new candidate for investigation in future studies...
  45. ncbi request reprint Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease
    Angelika D Wahner
    Department of Epidemiology, UCLA School of Public Health, University of California, Los Angeles, CA 90095 1772, USA
    Arch Neurol 64:836-40. 2007
    ....
  46. pmc A high-throughput method for cloning and sequencing human immunodeficiency virus type 1 integration sites
    Sanggu Kim
    Department of Molecular and Medical Pharmacology, Molecular Biology Institute, and UCLA AIDS Institute, UCLA School of Medicine, Los Angeles, CA 90095, USA
    J Virol 80:11313-21. 2006
    ....
  47. ncbi request reprint Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1)
    Paivi Pajukanta
    Department of Human Genetics, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California 90095 7088, USA
    Nat Genet 36:371-6. 2004
    ..USF1 encodes a transcription factor known to regulate several genes of glucose and lipid metabolism...
  48. pmc The chromosome 11 region from strain 129 provides protection from sex reversal in XYPOS mice
    Ganka Nikolova
    Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Genetics 179:419-27. 2008
    ..We conclude that a chromosome 11 locus derived from 129Sl/SvImJ essentially protects against sex reversal in XYPOS mice. A number of genes located in this chromosome 11 region are discussed as potential candidates...
  49. pmc Female mate preference explains countergradient variation in the sexual coloration of guppies (Poecilia reticulata)
    Kerry A Deere
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA
    Proc Biol Sci 279:1684-90. 2012
    ..To our knowledge, this is the first direct evidence for a hypothesized agent of countergradient sexual selection...
  50. pmc Effect of pre-test genetic counseling for deaf adults on knowledge of genetic testing
    Erin E Baldwin
    Department of Psychiatry and Biobehavioral Sciences, UCLA, 760 Westwood Plaza, Room 47 422, Los Angeles, CA 90095, USA
    J Genet Couns 21:256-72. 2012
    ..Culturally and linguistically appropriate pre-test genetic counseling significantly improved deaf individuals' genetics knowledge. Assessing deaf individuals' prior beliefs is important for enhancing genetics knowledge...
  51. ncbi request reprint Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population
    Zehra Mustafa
    Botnar Research Centre, Institute of Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford OX3 7LD, UK
    Arthritis Rheum 52:3502-6. 2005
    ..Our objective was to assess whether the D repeat is associated with OA in UK Caucasians...
  52. pmc A genomewide screen for autism-spectrum disorders: evidence for a major susceptibility locus on chromosome 3q25-27
    Mari Auranen
    Department of Molecular Medicine, National Public Health Institute, University of Helsinki, Finland
    Am J Hum Genet 71:777-90. 2002
    ....
  53. pmc Genetic association analysis of RHOB and TXNDC3 in osteoarthritis
    John Loughlin
    Am J Hum Genet 80:383-6; author reply 386-7. 2007
  54. ncbi request reprint Long-term survivors in Nairobi: complete HIV-1 RNA sequences and immunogenetic associations
    Guowei Fang
    Wadsworth Center, NY State Department of Health, Albany, New York 12208, USA
    J Infect Dis 190:697-701. 2004
    ..0048). Studying the interaction among immunogenetics, immune responses, and viral sequences from all HIV-1 subtypes may increase our understanding of slow HIV-1 disease progression...
  55. ncbi request reprint Presence of a primary hip osteoarthritis susceptibility locus on chromosome 6: comment on the article by Meenagh et al
    Kay Chapman
    Arthritis Rheum 54:1026-7. 2006
  56. ncbi request reprint Site and gender specificity of inheritance of bone mineral density
    Emma L Duncan
    Metabolic Bone Unit, Nuffield Orthopaedic Centre, Oxford, United Kingdom
    J Bone Miner Res 18:1531-8. 2003
    ..Spine BMD correlated more strongly in male-male comparisons and hip BMD in female-female comparisons, consistent with gender- and site-specificity of BMD heritability...

Research Grants1

  1. Maternal/fetal genotype incompatibility in schizophrenia
    Janet Sinsheimer; Fiscal Year: 2003
    ..This proposal is important because it could lead to a concrete research model in which the essential genetic and environmental elements involved in the etiology of schizophrenia could be studied precisely. ..