- Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organismsAmit U Sinha
Department of Computer Science, University of Cincinnati, Cincinnati, OH 45221, USA
BMC Bioinformatics 8:82. 2007..Therefore, existing tools and resources that facilitate identification, visualization and analysis of synteny need to be further improved to provide a flexible platform for such analysis, especially in the context of multiple genomes...
- Dissecting microregulation of a master regulatory networkAmit U Sinha
Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, USA
BMC Genomics 9:88. 2008..While it has been reported that some of the p53's functions are microRNA-mediated, it is not known as to how many other microRNAs might contribute to the p53-mediated tumorigenesis...
- H3K79 methylation profiles define murine and human MLL-AF4 leukemiasAndrei V Krivtsov
Division of Hematology Oncology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Cancer Cell 14:355-68. 2008..We thus demonstrate that ectopic H3K79 methylation is a distinguishing feature of murine and human MLL-AF4 ALLs and is important for maintenance of MLL-AF4-driven gene expression...