Manvendra K Singh

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development
    Manvendra K Singh
    Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 286:41036-45. 2011
  2. pmc Semaphorin 3d signaling defects are associated with anomalous pulmonary venous connections
    Karl Degenhardt
    Department of Pediatrics, Division of Cardiology, Children s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Nat Med 19:760-5. 2013
  3. pmc Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects
    Ying Zhang
    Department of Cell and Developmental Biology, Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA
    Dev Biol 325:82-93. 2009
  4. pmc Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice
    Manvendra K Singh
    Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Biol Chem 285:1765-72. 2010
  5. pmc New approaches under development: cardiovascular embryology applied to heart disease
    Karl Degenhardt
    Division of Cardiology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Clin Invest 123:71-4. 2013
  6. pmc Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression
    Nikhil Singh
    Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Dev Biol 377:333-44. 2013

Collaborators

Detail Information

Publications6

  1. pmc MicroRNA-processing enzyme Dicer is required in epicardium for coronary vasculature development
    Manvendra K Singh
    Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 286:41036-45. 2011
    ..These results demonstrate a critical role for Dicer, and by implication miRNAs, in murine epicardial development...
  2. pmc Semaphorin 3d signaling defects are associated with anomalous pulmonary venous connections
    Karl Degenhardt
    Department of Pediatrics, Division of Cardiology, Children s Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Nat Med 19:760-5. 2013
    ..These results identify Sema3d as a crucial pulmonary venous patterning cue and provide experimental evidence for an alternate developmental model to explain abnormal pulmonary venous connections...
  3. pmc Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects
    Ying Zhang
    Department of Cell and Developmental Biology, Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA
    Dev Biol 325:82-93. 2009
    ..These results demonstrate an important role for PlexinD1 in embryonic and adult vasculature...
  4. pmc Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice
    Manvendra K Singh
    Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Biol Chem 285:1765-72. 2010
    ..These results demonstrate functional redundancy between Gata4 and Gata5 during cardiac development and implicate Gata5 as a candidate modifier gene for congenital heart disease...
  5. pmc New approaches under development: cardiovascular embryology applied to heart disease
    Karl Degenhardt
    Division of Cardiology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    J Clin Invest 123:71-4. 2013
    ..In particular, research in stem cell biology, the cardiomyocyte lineage, and the interactions of the myocardium and epicardium have opened the door to new approaches for healing the injured heart...
  6. pmc Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression
    Nikhil Singh
    Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Dev Biol 377:333-44. 2013
    ..These results suggest that Hdac3 serves as a critical regulator of craniofacial morphogenesis, in part by repressing core apoptotic pathways in cranial neural crest cells...