Elyse J Singer

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Stability of human immunodeficiency virus type 1 RNA in cerebrospinal fluid determined with the AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive)
    Elyse J Singer
    Department of Neurology, School of Medicine, University of California at Los Angeles, 11645 Wilshire Boulevard, Suite 770, Los Angeles, CA 90025, USA
    J Clin Microbiol 40:3863-4. 2002
  2. pmc Neurologic presentations of AIDS
    Elyse J Singer
    Department of Neurology, David Geffen School of Medicine at UCLA, 11645 Wilshire Boulevard, Suite 770, Los Angeles, CA 90025, USA
    Neurol Clin 28:253-75. 2010
  3. pmc Transcriptome analysis of HIV-infected peripheral blood monocytes: gene transcripts and networks associated with neurocognitive functioning
    Andrew J Levine
    Department of Neurology, National Neurological AIDS Bank, David Geffen School of Medicine, University of California, Los Angeles, United States Electronic address
    J Neuroimmunol 265:96-105. 2013
  4. doi request reprint Coronary atherosclerotic lesions in human immunodeficiency virus-infected patients: a histopathologic study
    Robert G Micheletti
    University of California, Los Angeles, Los Angeles, CA, USA
    Cardiovasc Pathol 18:28-36. 2009
  5. ncbi request reprint Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults
    Andrew J Levine
    National Neurological AIDS Bank, Department of Neurology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 34:78-91. 2012
  6. pmc Depression, cognition, and self-appraisal of functional abilities in HIV: an examination of subjective appraisal versus objective performance
    April D Thames
    Semel Institute for Neuroscience and Human Behavior, School of Medicine, University of California Los Angeles, CA 90095, USA
    Clin Neuropsychol 25:224-43. 2011
  7. pmc Genome-wide association study of neurocognitive impairment and dementia in HIV-infected adults
    Andrew J Levine
    National Neurological AIDS Bank, Department of Neurology, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA
    Am J Med Genet B Neuropsychiatr Genet 159:669-83. 2012
  8. pmc Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer's disease
    Andrew J Levine
    Department of Neurology, National Neurological AIDS Bank, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA
    BMC Med Genomics 6:4. 2013
  9. ncbi request reprint The role of host genetics in the susceptibility for HIV-associated neurocognitive disorders
    Andrew J Levine
    National Neurological AIDS Bank, Department of Neurology, University of California Los Angeles David Geffen School of Medicine, 11645 Wilshire Blvd, Suite 770, Los Angeles, CA, 90025, USA
    AIDS Behav 13:118-32. 2009
  10. pmc An exploratory study of long-term neurocognitive outcomes following recovery from opportunistic brain infections in HIV+ adults
    Andrew J Levine
    Los Angeles National Neurological AIDS Bank, University of California, Los Angeles, CA 90025, USA
    J Clin Exp Neuropsychol 30:836-43. 2008

Detail Information

Publications24

  1. pmc Stability of human immunodeficiency virus type 1 RNA in cerebrospinal fluid determined with the AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive)
    Elyse J Singer
    Department of Neurology, School of Medicine, University of California at Los Angeles, 11645 Wilshire Boulevard, Suite 770, Los Angeles, CA 90025, USA
    J Clin Microbiol 40:3863-4. 2002
    ..5 (ultrasensitive). While a statistically significant decrease from the baseline was observed at 24 h, but not at 6 or 12 h, and with one freeze-thaw cycle, all changes were within the range of intra-assay variability...
  2. pmc Neurologic presentations of AIDS
    Elyse J Singer
    Department of Neurology, David Geffen School of Medicine at UCLA, 11645 Wilshire Boulevard, Suite 770, Los Angeles, CA 90025, USA
    Neurol Clin 28:253-75. 2010
    ....
  3. pmc Transcriptome analysis of HIV-infected peripheral blood monocytes: gene transcripts and networks associated with neurocognitive functioning
    Andrew J Levine
    Department of Neurology, National Neurological AIDS Bank, David Geffen School of Medicine, University of California, Los Angeles, United States Electronic address
    J Neuroimmunol 265:96-105. 2013
    ..We hypothesized that transcriptome changes in peripheral blood monocytes relate to neurocognitive functioning in HIV+ individuals, and that such alterations could be useful as biomarkers of worsening HAND...
  4. doi request reprint Coronary atherosclerotic lesions in human immunodeficiency virus-infected patients: a histopathologic study
    Robert G Micheletti
    University of California, Los Angeles, Los Angeles, CA, USA
    Cardiovasc Pathol 18:28-36. 2009
    ..Studies suggest human immunodeficiency virus-positive (HIV+) patients have an increased risk of coronary artery disease (CAD), yet little is known about the histopathology, severity, or distribution of lesions...
  5. ncbi request reprint Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults
    Andrew J Levine
    National Neurological AIDS Bank, Department of Neurology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, USA
    J Clin Exp Neuropsychol 34:78-91. 2012
    ..We report analyses examining the main effects of functional polymorphisms within dopamine-modulating genes, as well as their interactive effects with disease severity, upon neurocognitive functioning in HIV+ adults...
  6. pmc Depression, cognition, and self-appraisal of functional abilities in HIV: an examination of subjective appraisal versus objective performance
    April D Thames
    Semel Institute for Neuroscience and Human Behavior, School of Medicine, University of California Los Angeles, CA 90095, USA
    Clin Neuropsychol 25:224-43. 2011
    ..Together, these results suggest that over-reliance on self-reported functional status poses risk for error when diagnoses require documentation of both cognitive impairment and associated functional disability in everyday life...
  7. pmc Genome-wide association study of neurocognitive impairment and dementia in HIV-infected adults
    Andrew J Levine
    National Neurological AIDS Bank, Department of Neurology, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA
    Am J Med Genet B Neuropsychiatr Genet 159:669-83. 2012
    ..Due to the relatively small sample size, future collaborative efforts that incorporate this dataset may still yield important findings...
  8. pmc Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer's disease
    Andrew J Levine
    Department of Neurology, National Neurological AIDS Bank, David Geffen School of Medicine at the University of California, Los Angeles, CA, USA
    BMC Med Genomics 6:4. 2013
    ..Additionally, we compare these data to those derived from brains of individuals with Alzheimer's disease (AD) in order to identify common pathways of neuropathogenesis...
  9. ncbi request reprint The role of host genetics in the susceptibility for HIV-associated neurocognitive disorders
    Andrew J Levine
    National Neurological AIDS Bank, Department of Neurology, University of California Los Angeles David Geffen School of Medicine, 11645 Wilshire Blvd, Suite 770, Los Angeles, CA, 90025, USA
    AIDS Behav 13:118-32. 2009
    ....
  10. pmc An exploratory study of long-term neurocognitive outcomes following recovery from opportunistic brain infections in HIV+ adults
    Andrew J Levine
    Los Angeles National Neurological AIDS Bank, University of California, Los Angeles, CA 90025, USA
    J Clin Exp Neuropsychol 30:836-43. 2008
    ....
  11. pmc Medication and finance management among HIV-infected adults: the impact of age and cognition
    April D Thames
    UCLA School of Medicine, Los Angeles, CA 90024
    J Clin Exp Neuropsychol 33:200-9. 2011
    ....
  12. ncbi request reprint The impact of neurobehavioral features on medication adherence in HIV: evidence from longitudinal models
    Stella E Panos
    a Department of Psychiatry and Biobehavioral Sciences, UCLA Geffen School of Medicine, Los Angeles, CA, USA
    AIDS Care 26:79-86. 2014
    ..Adherence behavior is multidetermined. Adequate assessment of these factors, combined with timely intervention, appears to be warranted in order to boost adherence rates. ..
  13. ncbi request reprint A case of primary HIV type 1 and cytomegalovirus coinfection presenting with widespread clinical disease
    Joseph Y Kim
    Department of Internal Medicine, Division of Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
    J Int Assoc Provid AIDS Care 13:196-9. 2014
    ..This and other similar cases demonstrate the need to consider CMV coinfection in acute HIV-1 disease, particularly in situations with significant end-organ damage. ..
  14. pmc HIV stroke risk: evidence and implications
    Elyse J Singer
    National Neurological AIDS Bank, Department of Neurology, David Geffen School of Medicine at UCLA, 11645 Wilshire Blvd, Suite 770, Los Angeles, CA 90025, USA
    Ther Adv Chronic Dis 4:61-70. 2013
    ..New prevention and treatment strategies tailored to the needs of the HIV+ population are needed to address this issue...
  15. pmc Neurocognition in individuals co-infected with HIV and hepatitis C
    Charles H Hinkin
    David Geffen School of Medicine, University of California, Los Angeles, 760 Westwood Plaza, Room C8 747, Los Angeles, CA 90024, USA
    J Addict Dis 27:11-7. 2008
    ..Finally, we discuss implications of these findings and potential future directions for research in this area...
  16. ncbi request reprint NeuroAIDS: characteristics and diagnosis of the neurological complications of AIDS
    Alireza Minagar
    Department of Neurology, Louisiana State University Health Sciences Center Shreveport, Shreveport, Louisiana, USA
    Mol Diagn Ther 12:25-43. 2008
    ....
  17. pmc Hormone replacement therapy and risk for neurodegenerative diseases
    Richelin V Dye
    Longevity Center, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at the University of California, Los Angeles, CA 90025, USA
    Int J Alzheimers Dis 2012:258454. 2012
    ..Limits to the existing research are discussed, along with proposed future directions for the investigation of HRT and neurodegenerative diseases...
  18. pmc HIV-1 Antigens in Neurons of Cocaine-Abusing Patients
    Milan Fiala
    Departments of Medicine, UCLA School of Medicine, Los Angeles, California, USA
    Open Virol J 2:24-31. 2008
    ..Cocaine effects may be important in vivo since the neurons of drug abusing patients with HIV-1 associated dementia displayed gp120, p24 and Nef...
  19. ncbi request reprint Calcification of the internal elastic lamina of coronary arteries
    Robert G Micheletti
    Department of Medicine, Division of Infectious Diseases, University of California at Los Angeles, Los Angeles, CA 90035, USA
    Mod Pathol 21:1019-28. 2008
    ..Internal elastic lamina calcification may result from premature aging due to HIV disease and chronic illness or from metabolic disorders in HIV+ patients...
  20. ncbi request reprint Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV
    Steven Paul Woods
    University of California, San Diego, CA 92103, USA
    J Clin Exp Neuropsychol 26:759-78. 2004
    ..Not surprisingly, most diagnostic disagreements concerned the etiology of impairments in persons with medical and neuropsychiatric risk factors in addition to HIV...
  21. ncbi request reprint Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study
    Giovanni Schifitto
    University of Rochester, Rochester, New York 14620, USA
    AIDS 21:1877-86. 2007
    ..To assess the safety and efficacy of memantine, an uncompetitive antagonist of the N-methyl-D-aspartate receptor as treatment of HIV-associated cognitive impairment...
  22. ncbi request reprint A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy
    Giovanni Schifitto
    University of Rochester, Rochester, New York 14620, USA
    J Neurovirol 12:328-31. 2006
    ..Results were similar to those of other pilot studies of memantine for neuropathic pain unrelated to HIV, suggesting that memantine is ineffective for the symptomatic treatment of HIV-associated SDSP...
  23. pmc Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients
    Petronela Ancuta
    Dana Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 3:e2516. 2008
    ....
  24. ncbi request reprint Patient page. A new clue in the mystery of neuro-AIDS
    Elyse J Singer
    Neurology 60:E12-3. 2003