Research Topics
| L C SincichSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Oriented axon projections in primary visual cortex of the monkeyL C Sincich
Program in Neuroscience and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
J Neurosci 21:4416-26. 2001..Thus local axons produce a field of monosynaptic excitation that aligns with orientation axes and reaches neurons that have receptive fields which are adjacent in visual space...
Divided by cytochrome oxidase: a map of the projections from V1 to V2 in macaquesLawrence C Sincich
Beckman Vision Center, University of California, San Francisco, San Francisco, CA 94143 0730, USA
Science 295:1734-7. 2002..Projection of interpatches to common V2 stripe types (pale and thick) merges parvo and magno inputs, making it likely that these functional channels are distributed strongly to both dorsal and ventral streams...
Pale cytochrome oxidase stripes in V2 receive the richest projection from macaque striate cortexLawrence C Sincich
Beckman Vision Center, University of California, San Francisco, San Francisco, California 94143, USA
J Comp Neurol 447:18-33. 2002..Therefore, V2 receives interleaved projections from V1 and the pulvinar. Because these projections favor different stripe types, they may target separate populations of neurons...
An albino-like decussation error in the optic chiasm revealed by anomalous ocular dominance columnsLawrence C Sincich
Beckman Vision Center, University of California San Francisco, San Francisco 94143 0730, USA
Vis Neurosci 19:541-5. 2002....
Independent projection streams from macaque striate cortex to the second visual area and middle temporal areaLawrence C Sincich
Beckman Vision Center, University of California, San Francisco, San Francisco, California 94143 0730, USA
J Neurosci 23:5684-92. 2003..The results demonstrate that primary sensory cortices can use multiple projection strategies to distribute signals to higher areas, and suggest that feedforward projections may route signals with more specificity than feedback pathways...
Bypassing V1: a direct geniculate input to area MTLawrence C Sincich
Beckman Vision Center, University of California, 10 Koret Way, San Francisco, California 94143, USA
Nat Neurosci 7:1123-8. 2004....
Thalamic filtering of retinal spike trains by postsynaptic summationMatteo Carandini
Smith Kettlewell Eye Research Institute, San Francisco, CA, USA
J Vis 7:20.1-11. 2007..This simple form of integration explains the response differences between a geniculate neuron and its main retinal driver, and thereby determines the flow of visual information to cortex...
Preserving information in neural transmissionLawrence C Sincich
Beckman Vision Center, University of California, San Francisco, California 94143, USA
J Neurosci 29:6207-16. 2009....
Resolving single cone inputs to visual receptive fieldsLawrence C Sincich
Beckman Vision Center, University of California, San Francisco, San Francisco, California, USA
Nat Neurosci 12:967-9. 2009..Parvocellular LGN neurons mapped in this manner responded with high reliability to stimulation of single cones...
Complete pattern of ocular dominance columns in human primary visual cortexDaniel L Adams
Beckman Vision Center, Program in Neuroscience, University of California, San Francisco, San Francisco, California 94143 0730, USA
J Neurosci 27:10391-403. 2007..In one subject, monocular visual loss began at age 4 months, causing shrinkage of ocular dominance columns. In V2, which had a larger surface area than V1, CO stripes were present but could not be classified as thick or thin...
Transmission of spike trains at the retinogeniculate synapseLawrence C Sincich
Beckman Vision Center, University of California, San Francisco, San Francisco, California 94143, USA
J Neurosci 27:2683-92. 2007..Hence, the timing of EPSPs arising from the primary retinal driver governs synaptic efficacy and provides the basis for successful retinogeniculate transmission...
V1 interpatch projections to v2 thick stripes and pale stripesLawrence C Sincich
Beckman Vision Center, University of California, San Francisco, San Francisco, California 94143 0730, USA
J Neurosci 30:6963-74. 2010....
The circuitry of V1 and V2: integration of color, form, and motionLawrence C Sincich
Beckman Vision Center, University of California San Francisco, San Francisco, CA 94143, USA
Annu Rev Neurosci 28:303-26. 2005..Each stream is composed of a mixture of magno, parvo, and konio geniculate signals. Further studies are required to elucidate how the patches and interpatches differ in the output they convey to extrastriate cortex...
Neurons in V1 patch columns project to V2 thin stripesLawrence C Sincich
Beckman Vision Center, University of California San Francisco, San Francisco, CA 94143 0730, USA
Cereb Cortex 17:935-41. 2007..However, multiple V1 layers innervate V2 thin stripes, and the projection from layer 5/6 does not respect the patch/interpatch dichotomy...
Complete flatmounting of the macaque cerebral cortexLawrence C Sincich
Beckman Vision Center, University of California-San Francisco, San Francisco 94143-0730, USA
Vis Neurosci 20:663-86. 2003..Flatmounting the cerebral cortex is a simple, efficient method that can be used routinely for mapping areas and connections in the macaque brain, the most widely used primate model of the human brain...
Input to V2 thin stripes arises from V1 cytochrome oxidase patchesLawrence C Sincich
Beckman Vision Center, University of California, San Francisco, California 94143, USA
J Neurosci 25:10087-93. 2005..This finding means that different signals are likely conveyed by patches and interpatches to V2...
