Research Topics
Genomes and Genes | Michael W SimsSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional studyMichael W Sims
Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Respir Res 9:13. 2008..Deficiency of this molecule induces emphysematous changes in murine lungs, but its significance in human COPD remains unclear...
Impact of pulmonary artery pressure on exercise function in severe COPDMichael W Sims
Department of Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Chest 136:412-9. 2009..Although pulmonary hypertension commonly complicates COPD, the functional consequences of increased pulmonary artery pressures in patients with this condition remain poorly defined...
Effect of single vs bilateral lung transplantation on plasma surfactant protein D levels in idiopathic pulmonary fibrosisMichael W Sims
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Chest 140:489-96. 2011..However, little is known about SP-D levels in the setting of lung transplantation...
Aerosol therapy for obstructive lung diseases: device selection and practice management issuesMichael W Sims
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Chest 140:781-8. 2011..This article reviews the aerosol devices currently available, discusses their relative merits in various clinical settings, and summarizes appropriate CPT coding for aerosol therapy...
Profile of aclidinium bromide in the treatment of chronic obstructive pulmonary diseaseMichael W Sims
Pulmonary, Allergy, and Critical Care Division, Airways Biology Initiative, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Int J Chron Obstruct Pulmon Dis 6:457-66. 2011..This article will provide a pharmacologic profile of aclidinium bromide and review the preclinical and clinical studies evaluating its safety and efficacy in the treatment of COPD...
Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13Yassine Amrani
Pulmonary, Allergy and Critical Care Division, Department of Medicine, University of Pennsylvania, TRL Suite 1200, 125 South 31st Street, Philadelphia, PA 19104, USA
Respir Res 11:104. 2010..The purpose of this study was to define the role of oxytocin in modulating human airway smooth muscle (HASMCs) function in the presence and absence of IL-13 and TNFalpha, cytokines known to be important in asthma...
