Patricia J Simpson-Haidaris

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc A putative role for platelet-derived PPARγ in vascular homeostasis demonstrated by anti-PPARγ induction of bleeding, thrombocytopenia and compensatory megakaryocytopoiesis
    Patricia J Simpson-Haidaris
    Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Rochester, NY 14642, USA pj
    J Biotechnol 150:417-27. 2010
  2. pmc Peroxisome proliferator-activated receptor gamma ligands enhance human B cell antibody production and differentiation
    Tatiana M Garcia-Bates
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Immunol 183:6903-12. 2009
  3. ncbi request reprint Cell type-specific differential induction of the human gamma-fibrinogen promoter by interleukin-6
    Hai Ou Duan
    Department of Medicine Hematology Oncology Division, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 281:12451-7. 2006
  4. ncbi request reprint Modification of Streptococcus mutans Cnm by PgfS Contributes to Adhesion, Endothelial Cell Invasion, and Virulence
    Alejandro Avilés-Reyes
    Center for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Bacteriol 196:2789-97. 2014
  5. pmc Role of peroxisome proliferator-activated receptor gamma and its ligands in the treatment of hematological malignancies
    Tatiana M Garcia-Bates
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    PPAR Res 2008:834612. 2008
  6. ncbi request reprint Regulated de novo biosynthesis of fibrinogen in extrahepatic epithelial cells in response to inflammation
    Sarah O Lawrence
    Department of Medicine Hematology Oncology Unit, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Thromb Haemost 92:234-43. 2004
  7. ncbi request reprint The VE-cadherin binding domain of fibrinogen induces endothelial barrier permeability and enhances transendothelial migration of malignant breast epithelial cells
    Abha Sahni
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Int J Cancer 125:577-84. 2009
  8. pmc The collagen-binding protein Cnm is required for Streptococcus mutans adherence to and intracellular invasion of human coronary artery endothelial cells
    Jacqueline Abranches
    Center for Oral Biology, University of Rochester Medical Center, Box 611, 601 Elmwood Ave, Rochester, NY 14642, USA
    Infect Immun 79:2277-84. 2011

Collaborators

Detail Information

Publications8

  1. pmc A putative role for platelet-derived PPARγ in vascular homeostasis demonstrated by anti-PPARγ induction of bleeding, thrombocytopenia and compensatory megakaryocytopoiesis
    Patricia J Simpson-Haidaris
    Department of Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Rochester, NY 14642, USA pj
    J Biotechnol 150:417-27. 2010
    ..Furthermore, a major pitfall associated with MoAb production against closely related molecules is that monoclonicity does not guarantee monospecificity, an issue worth further scientific scrutiny...
  2. pmc Peroxisome proliferator-activated receptor gamma ligands enhance human B cell antibody production and differentiation
    Tatiana M Garcia-Bates
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Immunol 183:6903-12. 2009
    ..These new findings indicate that low doses of PPARgamma/RXRalpha ligands could be used as a new type of adjuvant to stimulate Ab production...
  3. ncbi request reprint Cell type-specific differential induction of the human gamma-fibrinogen promoter by interleukin-6
    Hai Ou Duan
    Department of Medicine Hematology Oncology Division, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 281:12451-7. 2006
    ..Together, the data suggest tissue-specific differences in IL-6-receptor-gp130-coupled signaling, thereby limiting the extent of Stat3 activation and gammaFBG expression during lung inflammation...
  4. ncbi request reprint Modification of Streptococcus mutans Cnm by PgfS Contributes to Adhesion, Endothelial Cell Invasion, and Virulence
    Alejandro Avilés-Reyes
    Center for Oral Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Bacteriol 196:2789-97. 2014
    ..In conclusion, this study demonstrates that Cnm is a glycoprotein and that posttranslational modification mediated by PgfS contributes to the virulence-associated phenotypes linked to Cnm. ..
  5. pmc Role of peroxisome proliferator-activated receptor gamma and its ligands in the treatment of hematological malignancies
    Tatiana M Garcia-Bates
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    PPAR Res 2008:834612. 2008
    ..Understanding the diverse properties of PPARgamma ligands is crucial for the development of new therapeutic approaches for hematological malignancies...
  6. ncbi request reprint Regulated de novo biosynthesis of fibrinogen in extrahepatic epithelial cells in response to inflammation
    Sarah O Lawrence
    Department of Medicine Hematology Oncology Unit, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Thromb Haemost 92:234-43. 2004
    ....
  7. ncbi request reprint The VE-cadherin binding domain of fibrinogen induces endothelial barrier permeability and enhances transendothelial migration of malignant breast epithelial cells
    Abha Sahni
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Int J Cancer 125:577-84. 2009
    ..Hence, Fg-beta(15-42) represents a potential molecular target for therapeutic intervention of breast cancer metastasis...
  8. pmc The collagen-binding protein Cnm is required for Streptococcus mutans adherence to and intracellular invasion of human coronary artery endothelial cells
    Jacqueline Abranches
    Center for Oral Biology, University of Rochester Medical Center, Box 611, 601 Elmwood Ave, Rochester, NY 14642, USA
    Infect Immun 79:2277-84. 2011
    ..Thus, Cnm is required for S. mutans invasion of endothelial cells and possibly represents an important virulence factor of S. mutans that may contribute to cardiovascular infections and pathologies...