J K Simosky

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Clozapine improves deficient inhibitory auditory processing in DBA/2 mice, via a nicotinic cholinergic mechanism
    Johanna K Simosky
    Department of Pharmacology, University of Colorado Health Sciences Center, Campus Box C268 71, 4200 East 9th Avenue, Denver, CO 80262, USA
    Psychopharmacology (Berl) 165:386-96. 2003
  2. ncbi request reprint Nicotinic agonists and psychosis
    J K Simosky
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Curr Drug Targets CNS Neurol Disord 1:149-62. 2002
  3. ncbi request reprint Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice
    J K Simosky
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Biol Psychiatry 50:493-500. 2001
  4. ncbi request reprint Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors
    N R Zahniser
    Department of Pharmacology and Neuroscience Program, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Neurosci 20:5949-57. 2000

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Clozapine improves deficient inhibitory auditory processing in DBA/2 mice, via a nicotinic cholinergic mechanism
    Johanna K Simosky
    Department of Pharmacology, University of Colorado Health Sciences Center, Campus Box C268 71, 4200 East 9th Avenue, Denver, CO 80262, USA
    Psychopharmacology (Berl) 165:386-96. 2003
    ..The atypical antipsychotic clozapine also normalizes this deficit in schizophrenia patients, but by an unknown mechanism...
  2. ncbi request reprint Nicotinic agonists and psychosis
    J K Simosky
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Curr Drug Targets CNS Neurol Disord 1:149-62. 2002
    ..Additional avenues to the potential normalization of auditory gating deficits are also discussed, focusing on the novel efficacy of clozapine and the potential utility of allosteric modulators of nicotinic receptors...
  3. ncbi request reprint Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice
    J K Simosky
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Biol Psychiatry 50:493-500. 2001
    ..These studies agree with results from previous studies with subcutaneously administered DMXB-A...
  4. ncbi request reprint Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors
    N R Zahniser
    Department of Pharmacology and Neuroscience Program, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Neurosci 20:5949-57. 2000
    ..They also reinforce the ideas that D(2)Rs and A(2A)Rs are functionally opposed and that D(2)R-mediated effects normally predominate...