Research Topics
| Geza SimonSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Structural vascular changes in hypertension: role of angiotensin II, dietary sodium supplementation, and sympathetic stimulation, alone and in combination in ratsG Simon
Department of Medicine, VA Medical Center, Minneapolis, MN 55417, USA
Hypertension 37:255-60. 2001..The ultimate test of the hypertensinogenic potential of pressor stimuli alone or in combination is their long-term administration in physiologically meaningful doses to experimental animals...
Pathogenesis of structural vascular changes in hypertensionGeza Simon
Department of Medicine, VA Medical Center and University of Minnesota Medical School, Minneapolis, Minnesota 55417, USA
J Hypertens 22:3-10. 2004..Progressive trophic stimulation of preglomerular resistance vessels by itself may lead to hypertension. ANG II is prime candidate for such stimulus...
Experimental evidence for blood pressure-independent vascular effects of high sodium dietGeza Simon
Department of Medicine, VA Medical Center, Minneapolis, Minnesota 55410, USA
Am J Hypertens 16:1074-8. 2003..Further experimental evidence is needed to convince the scientific community that lifelong high sodium intake expedites cardiovascular aging and reduces life expectancy independently of its effect on BP...
Altered structure and distensibility of arteries in salt-fed ratsGeza Simon
Department of Medicine, VA Medical Center, Minneapolis, MN 55417, USA
J Hypertens 21:137-43. 2003..Habitual high-sodium diet may cause stiffening of arteries. The aim of this study was to investigate the long-term effects of physiologically relevant high-sodium diet on the structure and distensibility of arteries in rats...
Development of structural vascular changes in salt-fed ratsGeza Simon
Department of Medicine, VA Medical Center, Minneapolis, Minnesota, USA
Am J Hypertens 16:488-93. 2003..The long-term administration of a high salt diet leads to structural vascular changes in normotensive rats. There are important regional and segmental variations in the long-term adaptation of arteries to a high salt diet...
Role of angiotensin II, sympathetic stimulation and salt in the development of structural vascular changes in rat kidneyGeza Simon
Department of Medicine, VA Medical Center, Minneapolis, Minnesota 55417, USA
Clin Exp Pharmacol Physiol 30:476-81. 2003..It remains to be determined whether renal cortical structural changes are the cause of, or are compensatory for, chronic changes in blood pressure...
Dilation and reduced distensibility of rat carotid artery with agingGeza Simon
Department of Medicine, VA Medical Center, Minneapolis, Minnesota 55417, USA
Clin Exp Hypertens 27:459-66. 2005..Dilation (with early recruitment of collagen fibrils during pressure rise) rather than increased stiffness of wall components appears to be the cause of reduced distensibility of rat carotid artery in the early stages of aging...
Why do treated hypertensives suffer strokes? An internist's perspectiveGeza Simon
Medical Service, VA Medical Center and University of Minnesota Medical School, Minneapolis, MN 55417, USA
J Clin Hypertens (Greenwich) 4:338-44. 2002....
[Care in hypertension: guidelines and sources of error]Geza Simon
, Bem Rakparti Rendelo, Budapest
Orv Hetil 146:849-52. 2005
[Renovascular disease: challenge to general practitioners and internists]Geza Simon
Magyar Máltai Szeretet Szolgálat, Bem Rakparti Rendelo, Budapest
Orv Hetil 146:1733-6. 2005..Patients diagnosed with non-critical renal artery stenosis (< 80%) do not need immediate intervention, only close follow-up...
Altered structure and reduced distensibility of arteries in Dahl salt-sensitive ratsMarta Jaeckel
Department of Medicine, VA Medical Center, Minneapolis, Minnesota 55417, USA
J Hypertens 21:311-9. 2003..Structural and functional adaptation to salt sensitivity may occur on what is considered a 'normal' sodium diet...
J-shaped relationship in hypertensionGeza Simon
Ann Intern Med 138:78. 2003
